Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells

Journal of the Neurological Sciences

Volumn 368, Issue , 2016, Pages 223-230

  Wang, Yumin ^a   Miao, Yingchun ^b   Mir, Aamina Zia ^a   Cheng, Long ^c   Wang, Lina ^a   Zhao, Linan ^a   Cui, Qifu ^a   Zhao, Weili ^a   Wang, Hongquan ^a  

^a Chifeng University   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Alzheimer's disease; Beta amyloid; Heme oxygenase 1; Neuroprotection; Nrf2; Pinocembrin

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CASPASE 3; CYTOCHROME C; HEME OXYGENASE 1; NEUROPROTECTIVE AGENT; PINOCEMBRINE; PROTEIN BAX; PROTEIN BCL 2; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (25-35); FLAVANONE DERIVATIVE; HMOX1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; PEPTIDE FRAGMENT;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG INHIBITION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL LINE; NEUROPROTECTION; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; RNA INTERFERENCE; SH SY5Y CELL LINE; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; APOPTOSIS; CELL LINE, TUMOR; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVANONES; GENE EXPRESSION REGULATION, NEOPLASTIC; HEME OXYGENASE-1; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PEPTIDE FRAGMENTS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84978872515     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2016.07.010     Document Type: Article

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