Amyloid β protein aggravates neuronal senescence and cognitive deficits in 5XFAD mouse model of Alzheimer’s disease

Chinese Medical Journal

Volumn 129, Issue 15, 2016, Pages 1835-1844

  Wei, Zhen ^a   Chen, Xiao Chun ^a   Song, Yue ^a   Pan, Xiao Dong ^a   Dai, Xiao Man ^a   Zhang, Jing ^a   Cui, Xiao Li ^a   Wu, Xi Lin ^a   Zhu, Yuan Gui ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer s disease; Amyloid ; Cognition; P16; Senescence

Indexed keywords

AMYLOID BETA PROTEIN; CHLORAL HYDRATE; PHOSPHATE BUFFERED SALINE; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; SECRETASE;

5XFAD MOUSE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; GENE; HIPPOCAMPAL TISSUE; IMMUNOFLUORESCENCE; MALE; MORRIS WATER MAZE TEST; MOUSE; NERVE CELL CULTURE; NONHUMAN; P16 GENE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; WESTERN BLOTTING; Y-MAZE TEST; ANIMAL; BRAIN; C57BL MOUSE; CELL AGING; CELL CULTURE; COGNITION; DISEASE MODEL; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CELL AGING; CELLS, CULTURED; COGNITION; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84978646178     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.4103/0366-6999.186646     Document Type: Article

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