메뉴 건너뛰기




Volumn 18, Issue 1, 2015, Pages 57-89

Exercise attenuates the major hallmarks of aging

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC METABOLISM; AGING; ARTICLE; CARDIORESPIRATORY FITNESS; CELL COMMUNICATION; EXERCISE; FITNESS; FRAIL ELDERLY; GENOMIC INSTABILITY; HUMAN; MICROCIRCULATION; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; NERVE DEGENERATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; RESISTANCE TRAINING; SENESCENCE; TELOMERE; WALKING; AGED; CARDIOVASCULAR SYSTEM; CELL AGING; CYTOLOGY; DEGENERATIVE DISEASE; GENETIC EPIGENESIS; METABOLISM; MITOCHONDRION; MUSCLE; PHYSIOLOGY; QUALITY OF LIFE; SIGNAL TRANSDUCTION; STEM CELL; ULTRASTRUCTURE; VERY ELDERLY;

EID: 84923357729     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2014.1623     Document Type: Article
Times cited : (274)

References (410)
  • 1
    • 79959902659 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise
    • Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP, American College of Sports M. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise. Med Sci Sports Exerc 2011;43:1334-1359.
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1334-1359
    • American College of Sports M1    Garber, C.E.2    Blissmer, B.3    Deschenes, M.R.4    Franklin, B.A.5    Lamonte, M.J.6    Lee, I.M.7    Nieman, D.C.8    Swain, D.P.9
  • 5
    • 66349125143 scopus 로고    scopus 로고
    • Maximal oxygen intake and independence in old age
    • Shephard RJ. Maximal oxygen intake and independence in old age. Br J Sports Med 2009;43:342-346.
    • (2009) Br J Sports Med , vol.43 , pp. 342-346
    • Shephard, R.J.1
  • 8
    • 0028328457 scopus 로고
    • Cardiovascular responses to exercise. Effects of aging and exercise training in healthy men
    • Stratton JR, Levy WC, Cerqueira MD, Schwartz RS, Abrass IB. Cardiovascular responses to exercise. Effects of aging and exercise training in healthy men. Circulation 1994;89:1648-1655.
    • (1994) Circulation , vol.89 , pp. 1648-1655
    • Stratton, J.R.1    Levy, W.C.2    Cerqueira, M.D.3    Schwartz, R.S.4    Abrass, I.B.5
  • 9
    • 0034787645 scopus 로고    scopus 로고
    • A longitudinal assessment of change in VO2max and maximal heart rate in master athletes
    • Hawkins SA, Marcell TJ, Victoria Jaque S, Wiswell RA. A longitudinal assessment of change in VO2max and maximal heart rate in master athletes. Med Sci Sports Exerc 2001;33:1744-1750.
    • (2001) Med Sci Sports Exerc , vol.33 , pp. 1744-1750
    • Hawkins, S.A.1    Marcell, T.J.2    Victoria Jaque, S.3    Wiswell, R.A.4
  • 10
    • 0036081852 scopus 로고    scopus 로고
    • Changes in maximal aerobic capacity with age in endurancetrained women: 7-yr follow-up
    • Eskurza I, Donato AJ, Moreau KL, Seals DR, Tanaka H. Changes in maximal aerobic capacity with age in endurancetrained women: 7-yr follow-up. J Appl Physiol 2002;92:2303-2308.
    • (2002) J Appl Physiol , vol.92 , pp. 2303-2308
    • Eskurza, I.1    Donato, A.J.2    Moreau, K.L.3    Seals, D.R.4    Tanaka, H.5
  • 11
    • 0019935632 scopus 로고
    • Maximal cardiac function in sedentary normal men and women: Comparison of agerelated changes
    • Hossack KF, Bruce RA. Maximal cardiac function in sedentary normal men and women: Comparison of agerelated changes. J Appl Physiol 1982;53:799-804.
    • (1982) J Appl Physiol , vol.53 , pp. 799-804
    • Hossack, K.F.1    Bruce, R.A.2
  • 13
    • 0032941024 scopus 로고    scopus 로고
    • Exercise cardiac function in young through elderly endurance trained women
    • Wiebe CG, Gledhill N, Jamnik VK, Ferguson S. Exercise cardiac function in young through elderly endurance trained women. Med Sci Sports Exerc 1999;31:684-691.
    • (1999) Med Sci Sports Exerc , vol.31 , pp. 684-691
    • Wiebe, C.G.1    Gledhill, N.2    Jamnik, V.K.3    Ferguson, S.4
  • 14
    • 0030911583 scopus 로고    scopus 로고
    • Skeletal muscle mass and the reduction of VO2max in trained older subjects
    • Proctor DN, Joyner MJ. Skeletal muscle mass and the reduction of VO2max in trained older subjects. J Appl Physiol 1997;82:1411-1415.
    • (1997) J Appl Physiol , vol.82 , pp. 1411-1415
    • Proctor, D.N.1    Joyner, M.J.2
  • 15
    • 0027939622 scopus 로고
    • Contribution of body composition and physical activity to agerelated decline in peak VO2 in men and women
    • Toth MJ, Gardner AW, Ades PA, Poehlman ET. Contribution of body composition and physical activity to agerelated decline in peak VO2 in men and women. J Appl Physiol 1994;77:647-652.
    • (1994) J Appl Physiol , vol.77 , pp. 647-652
    • Toth, M.J.1    Gardner, A.W.2    Ades, P.A.3    Poehlman, E.T.4
  • 16
    • 0037422592 scopus 로고    scopus 로고
    • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part I: Aging arteries: A "set up" for vascular disease
    • Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: Aging arteries: a "set up" for vascular disease. Circulation 2003;107:139-146.
    • (2003) Circulation , vol.107 , pp. 139-146
    • Lakatta, E.G.1    Levy, D.2
  • 18
    • 33846979103 scopus 로고    scopus 로고
    • Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans
    • Schrage WG, Eisenach JH, Joyner MJ. Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans. J Physiol 2007;579:227-236.
    • (2007) J Physiol , vol.579 , pp. 227-236
    • Schrage, W.G.1    Eisenach, J.H.2    Joyner, M.J.3
  • 19
    • 0032413531 scopus 로고    scopus 로고
    • Age-related changes in the microcirculation of skeletal muscle
    • Degens H. Age-related changes in the microcirculation of skeletal muscle. Adv Exp Med Biol 1998;454:343-348.
    • (1998) Adv Exp Med Biol , vol.454 , pp. 343-348
    • Degens, H.1
  • 20
    • 0034234773 scopus 로고    scopus 로고
    • Oxidative capacity and ageing in human muscle
    • Conley KE, Jubrias SA, Esselman PC. Oxidative capacity and ageing in human muscle. J Physiol 2000;526(Pt 1):203-210.
    • (2000) J Physiol , vol.526 , pp. 203-210
    • Conley, K.E.1    Jubrias, S.A.2    Esselman, P.C.3
  • 21
    • 0033927851 scopus 로고    scopus 로고
    • Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr
    • Janssen I, Heymsfield SB, Wang ZM, Ross R. Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr. J Appl Physiol. 2000;89:81-88.
    • (2000) J Appl Physiol , vol.89 , pp. 81-88
    • Janssen, I.1    Heymsfield, S.B.2    Wang, Z.M.3    Ross, R.4
  • 22
    • 0023856536 scopus 로고
    • What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
    • Lexell J, Taylor CC, Sjostrom M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J Neurol Sci 1988;84:275-294.
    • (1988) J Neurol Sci , vol.84 , pp. 275-294
    • Lexell, J.1    Taylor, C.C.2    Sjostrom, M.3
  • 30
    • 7544233112 scopus 로고    scopus 로고
    • Effects of aging on muscle fibre type and size
    • Deschenes MR. Effects of aging on muscle fibre type and size. Sports Med 2004;34:809-824.
    • (2004) Sports Med , vol.34 , pp. 809-824
    • Deschenes, M.R.1
  • 34
    • 0141566914 scopus 로고    scopus 로고
    • Invited review: Aging and sarcopenia
    • Doherty TJ. Invited review: Aging and sarcopenia. J Appl Physiol 2003;95:1717-1727.
    • (2003) J Appl Physiol , vol.95 , pp. 1717-1727
    • Doherty, T.J.1
  • 35
    • 0141958058 scopus 로고    scopus 로고
    • Sarcopenia and aging
    • Kamel HK. Sarcopenia and aging. Nutr Rev 2003;61:157-167.
    • (2003) Nutr Rev , vol.61 , pp. 157-167
    • Kamel, H.K.1
  • 37
    • 0036239678 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations: A causal role in sarcopenia
    • McKenzie D, Bua E, McKiernan S, Cao Z, Aiken JM. Mitochondrial DNA deletion mutations: A causal role in sarcopenia. Eur J Biochem 2002;269:2010-2015.
    • (2002) Eur J Biochem , vol.269 , pp. 2010-2015
    • McKenzie, D.1    Bua, E.2    McKiernan, S.3    Cao, Z.4    Aiken, J.M.5
  • 38
    • 0042386022 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging
    • Pak JW, Herbst A, Bua E, Gokey N, McKenzie D, Aiken JM. Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging. Aging Cell 2003;2:1-7.
    • (2003) Aging Cell , vol.2 , pp. 1-7
    • Pak, J.W.1    Herbst, A.2    Bua, E.3    Gokey, N.4    McKenzie, D.5    Aiken, J.M.6
  • 39
    • 0035127889 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia
    • Wanagat J, Cao Z, Pathare P, Aiken JM. Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia. FASEB J 2001;15:322-332.
    • (2001) FASEB J , vol.15 , pp. 322-332
    • Wanagat, J.1    Cao, Z.2    Pathare, P.3    Aiken, J.M.4
  • 41
    • 50049116996 scopus 로고    scopus 로고
    • Target population for clinical trials on sarcopenia
    • Cesari M, Pahor M. Target population for clinical trials on sarcopenia. J Nutr Health Aging 2008;12:470-478.
    • (2008) J Nutr Health Aging , vol.12 , pp. 470-478
    • Cesari, M.1    Pahor, M.2
  • 43
    • 79952705322 scopus 로고    scopus 로고
    • Severe osteopenia and osteoporosis, sarcopenia, and frailty status in community-dwelling older women: Results from the Women's Health and Aging Study (WHAS) II
    • Frisoli A, Jr., Chaves PH, Ingham SJ, Fried LP. Severe osteopenia and osteoporosis, sarcopenia, and frailty status in community-dwelling older women: Results from the Women's Health and Aging Study (WHAS) II. Bone 2011;48:952-957.
    • (2011) Bone , vol.48 , pp. 952-957
    • Frisoli, A.1    Chaves, P.H.2    Ingham, S.J.3    Fried, L.P.4
  • 44
    • 33645141176 scopus 로고    scopus 로고
    • Influence of sarcopenia on the development of physical disability: The Cardiovascular Health Study
    • Janssen I. Influence of sarcopenia on the development of physical disability: The Cardiovascular Health Study. J Am Geriatr Soc 2006;54:56-62.
    • (2006) J Am Geriatr Soc , vol.54 , pp. 56-62
    • Janssen, I.1
  • 45
    • 0036246979 scopus 로고    scopus 로고
    • Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    • Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 2002;50:889-896.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 889-896
    • Janssen, I.1    Heymsfield, S.B.2    Ross, R.3
  • 49
    • 34347390805 scopus 로고    scopus 로고
    • Pharmacological treatment of geriatric cachexia: Evidence and safety in perspective
    • Yeh SS, Lovitt S, Schuster MW. Pharmacological treatment of geriatric cachexia: Evidence and safety in perspective. J Am Med Dir Assoc 2007;8:363-377.
    • (2007) J Am Med Dir Assoc , vol.8 , pp. 363-377
    • Yeh, S.S.1    Lovitt, S.2    Schuster, M.W.3
  • 53
    • 84868365309 scopus 로고    scopus 로고
    • Sarcopenia: A novel clinical condition or still a matter for research?
    • Cesari M, Vellas B. Sarcopenia: A novel clinical condition or still a matter for research? J Am Med Dir Assoc 2012;13:766-767.
    • (2012) J Am Med Dir Assoc , vol.13 , pp. 766-767
    • Cesari, M.1    Vellas, B.2
  • 54
    • 79955612531 scopus 로고    scopus 로고
    • An overview of sarcopenia: Facts and numbers on prevalence and clinical impact
    • Von Haehling S, Morley JE, Anker SD. An overview of sarcopenia: Facts and numbers on prevalence and clinical impact. J Cachexia Sarcopenia Muscle 2010;1:129-133.
    • (2010) J Cachexia Sarcopenia Muscle , vol.1 , pp. 129-133
    • Von Haehling, S.1    Morley, J.E.2    Anker, S.D.3
  • 55
    • 84858375770 scopus 로고    scopus 로고
    • The frailty syndrome: A comprehensive review
    • Heuberger RA. The frailty syndrome: A comprehensive review. J Nutr Gerontol Geriatr 2011;30:315-368.
    • (2011) J Nutr Gerontol Geriatr , vol.30 , pp. 315-368
    • Heuberger, R.A.1
  • 57
    • 16544391075 scopus 로고    scopus 로고
    • Operationalizing a frailty index from a standardized comprehensive geriatric assessment
    • Jones DM, Song X, Rockwood K. Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc 2004;52:1929-1933.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 1929-1933
    • Jones, D.M.1    Song, X.2    Rockwood, K.3
  • 60
  • 63
    • 1642329318 scopus 로고    scopus 로고
    • Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care
    • Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004;59:255-263.
    • (2004) J Gerontol a Biol Sci Med Sci , vol.59 , pp. 255-263
    • Fried, L.P.1    Ferrucci, L.2    Darer, J.3    Williamson, J.D.4    Anderson, G.5
  • 65
    • 0034687139 scopus 로고    scopus 로고
    • Regular aerobic exercise prevents and restores age-related declines in endotheliumdependent vasodilation in healthy men
    • De Souza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, Seals DR. Regular aerobic exercise prevents and restores age-related declines in endotheliumdependent vasodilation in healthy men. Circulation 2000;102:1351-1357.
    • (2000) Circulation , vol.102 , pp. 1351-1357
    • De Souza, C.A.1    Shapiro, L.F.2    Clevenger, C.M.3    Dinenno, F.A.4    Monahan, K.D.5    Tanaka, H.6    Seals, D.R.7
  • 66
    • 9244228465 scopus 로고    scopus 로고
    • Effect of exercise training on endothelium-derived nitric oxide function in humans
    • Green DJ, Maiorana A, O'Driscoll G, Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 2004;561:1-25.
    • (2004) J Physiol , vol.561 , pp. 1-25
    • Green, D.J.1    Maiorana, A.2    O'Driscoll, G.3    Taylor, R.4
  • 67
    • 0141761438 scopus 로고    scopus 로고
    • Effects of exercise training on conduit and resistance vessel function in treated and untreated hypercholesterolaemic subjects
    • Walsh JH, Yong G, Cheetham C, Watts GF, O'Driscoll GJ, Taylor RR, Green DJ. Effects of exercise training on conduit and resistance vessel function in treated and untreated hypercholesterolaemic subjects. Eur Heart J 2003;24:1681-1689.
    • (2003) Eur Heart J , vol.24 , pp. 1681-1689
    • Walsh, J.H.1    Yong, G.2    Cheetham, C.3    Watts, G.F.4    O'Driscoll, G.J.5    Taylor, R.R.6    Green, D.J.7
  • 68
    • 80052215318 scopus 로고    scopus 로고
    • Exercise-induced modulation of endothelial nitric oxide production
    • Gielen S, Sandri M, Erbs S, Adams V. Exercise-induced modulation of endothelial nitric oxide production. Curr Pharmaceut Biotech 2011;12:1375-1384.
    • (2011) Curr Pharmaceut Biotech , vol.12 , pp. 1375-1384
    • Gielen, S.1    Sandri, M.2    Erbs, S.3    Adams, V.4
  • 72
    • 70349629016 scopus 로고    scopus 로고
    • Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: Effect of endurance exercise training
    • Billman GE. Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: Effect of endurance exercise training. Am J Physiol Heart Circ Physiol 2009;297:H1171-H1193.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , pp. H1171-H1193
    • Billman, G.E.1
  • 73
    • 7244247007 scopus 로고    scopus 로고
    • Collateral damage: Cardiovascular consequences of chronic sympathetic activation with human aging
    • Seals DR, Dinenno FA. Collateral damage: Cardiovascular consequences of chronic sympathetic activation with human aging. Am J Physiol Heart Circ Physiol 2004;287:H1895-H1905.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , pp. H1895-H1905
    • Seals, D.R.1    Dinenno, F.A.2
  • 74
    • 0025311912 scopus 로고
    • Reduced postprandial skeletal muscle blood flow contributes to glucose intolerance in human obesity
    • Baron AD, Laakso M, Brechtel G, Hoit B, Watt C, Edelman SV. Reduced postprandial skeletal muscle blood flow contributes to glucose intolerance in human obesity. J Clin Endocrinol Metab 1990;70:1525-1533.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1525-1533
    • Baron, A.D.1    Laakso, M.2    Brechtel, G.3    Hoit, B.4    Watt, C.5    Edelman, S.V.6
  • 75
    • 0027195457 scopus 로고
    • Decreased peripheral blood flow in the pathogenesis of the metabolic syndrome comprising hypertension, hyperlipidemia, and hyperinsulinemia
    • Lind L, Lithell H. Decreased peripheral blood flow in the pathogenesis of the metabolic syndrome comprising hypertension, hyperlipidemia, and hyperinsulinemia. Am Heart J 1993;125:1494-1497.
    • (1993) Am Heart J , vol.125 , pp. 1494-1497
    • Lind, L.1    Lithell, H.2
  • 76
    • 0034669001 scopus 로고    scopus 로고
    • Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men
    • Monahan KD, Dinenno FA, Tanaka H, Clevenger CM, De Souza CA, Seals DR. Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men. J Physiol 2000;529(Pt 1):263-271.
    • (2000) J Physiol , vol.529 , pp. 263-271
    • Monahan, K.D.1    Dinenno, F.A.2    Tanaka, H.3    Clevenger, C.M.4    De Souza, C.A.5    Seals, D.R.6
  • 77
    • 55249104128 scopus 로고    scopus 로고
    • Effects of drug, biobehavioral and exercise therapies on heart rate variability in coronary artery disease: A systematic review
    • Nolan RP, Jong P, Barry-Bianchi SM, Tanaka TH, Floras JS. Effects of drug, biobehavioral and exercise therapies on heart rate variability in coronary artery disease: A systematic review. Eur J Cardiovasc Prev Rehabil 2008;15:386-396.
    • (2008) Eur J Cardiovasc Prev Rehabil , vol.15 , pp. 386-396
    • Nolan, R.P.1    Jong, P.2    Barry-Bianchi, S.M.3    Tanaka, T.H.4    Floras, J.S.5
  • 79
    • 70049106960 scopus 로고    scopus 로고
    • Progressive resistance strength training for improving physical function in older adults
    • Liu CJ, Latham NK. Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev 2009 CD002759.
    • (2009) Cochrane Database Syst Rev , pp. CD002759
    • Liu, C.J.1    Latham, N.K.2
  • 81
    • 34548209954 scopus 로고    scopus 로고
    • Physical activity and public health in older adults: Recommendation from the American College of Sports Medicine and the American Heart Association
    • Nelson ME, Rejeski WJ, Blair SN, Duncan PW, Judge JO, King AC, Macera CA, Castaneda-Sceppa C. Physical activity and public health in older adults: Recommendation from the American College of Sports Medicine and the American Heart Association. Circulation 2007;116:1094-1105.
    • (2007) Circulation , vol.116 , pp. 1094-1105
    • Nelson, M.E.1    Rejeski, W.J.2    Blair, S.N.3    Duncan, P.W.4    Judge, J.O.5    King, A.C.6    Macera, C.A.7    Castaneda-Sceppa, C.8
  • 82
    • 0034931287 scopus 로고    scopus 로고
    • Velocity training induces power-specific adaptations in highly functioning older adults
    • Earles DR, Judge JO, Gunnarsson OT. Velocity training induces power-specific adaptations in highly functioning older adults. Arch Phys Med Rehabil 2001;82:872-878.
    • (2001) Arch Phys Med Rehabil , vol.82 , pp. 872-878
    • Earles, D.R.1    Judge, J.O.2    Gunnarsson, O.T.3
  • 83
    • 0037250425 scopus 로고    scopus 로고
    • High-velocity resistance training for increasing peak muscle power in elderly women
    • Evans WJ. High-velocity resistance training for increasing peak muscle power in elderly women. Clin J Sport Med 2003;13:66.
    • (2003) Clin J Sport Med , vol.13 , pp. 66
    • Evans, W.J.1
  • 84
    • 56849083271 scopus 로고    scopus 로고
    • Explosive heavy-resistance training in old and very old adults: Changes in rapid muscle force, strength and power
    • Caserotti P, Aagaard P, Larsen JB, Puggaard L. Explosive heavy-resistance training in old and very old adults: Changes in rapid muscle force, strength and power. Scand J Med Sci Sports 2008;18:773-782.
    • (2008) Scand J Med Sci Sports , vol.18 , pp. 773-782
    • Caserotti, P.1    Aagaard, P.2    Larsen, J.B.3    Puggaard, L.4
  • 87
    • 0027167130 scopus 로고
    • The effect of a weighted vest on perceived health status and bone density in older persons
    • Greendale GA, Hirsch SH, Hahn TJ. The effect of a weighted vest on perceived health status and bone density in older persons. Qual Life Res 1993;2:141-152.
    • (1993) Qual Life Res , vol.2 , pp. 141-152
    • Greendale, G.A.1    Hirsch, S.H.2    Hahn, T.J.3
  • 88
    • 0031608210 scopus 로고    scopus 로고
    • Weighted vest exercise improves indices of fall risk in older women
    • Shaw JM, Snow CM. Weighted vest exercise improves indices of fall risk in older women. J Gerontol A Biol Sci Med Sci 1998;53:M53-M58.
    • (1998) J Gerontol a Biol Sci Med Sci , vol.53 , pp. M53-M58
    • Shaw, J.M.1    Snow, C.M.2
  • 90
    • 0034023498 scopus 로고    scopus 로고
    • A randomized trial of weighted vest use in ambulatory older adults: Strength, performance, and quality of life outcomes
    • Greendale GA, Salem GJ, Young JT, Damesyn M, Marion M, Wang MY, Reuben DB. A randomized trial of weighted vest use in ambulatory older adults: Strength, performance, and quality of life outcomes. J Am Geriatr Soc 2000;48:305-311.
    • (2000) J Am Geriatr Soc , vol.48 , pp. 305-311
    • Greendale, G.A.1    Salem, G.J.2    Young, J.T.3    Damesyn, M.4    Marion, M.5    Wang, M.Y.6    Reuben, D.B.7
  • 91
    • 33745236879 scopus 로고    scopus 로고
    • Effects of exercise programs on falls and mobility in frail and pre-frail older adults: A multicenter randomized controlled trial
    • Faber MJ, Bosscher RJ, Chin A P MJ, Van Wieringen PC. Effects of exercise programs on falls and mobility in frail and pre-frail older adults: A multicenter randomized controlled trial. Arch Phys Med Rehabil 2006;87:885-896.
    • (2006) Arch Phys Med Rehabil , vol.87 , pp. 885-896
    • Faber, M.J.1    Bosscher, R.J.2    Chin, A.P.M.J.3    Van Wieringen, P.C.4
  • 93
    • 80052604144 scopus 로고    scopus 로고
    • Impact of resistance exercise program on functional capacity and muscular strength of knee extensor in pre-frail community-dwelling older women: A randomized crossover trial
    • Lustosa LP, Silva JP, Coelho FM, Pereira DS, Parentoni AN, Pereira LS. Impact of resistance exercise program on functional capacity and muscular strength of knee extensor in pre-frail community-dwelling older women: A randomized crossover trial. Rev Bras Fisioter 2011;15:318-324.
    • (2011) Rev Bras Fisioter , vol.15 , pp. 318-324
    • Lustosa, L.P.1    Silva, J.P.2    Coelho, F.M.3    Pereira, D.S.4    Parentoni, A.N.5    Pereira, L.S.6
  • 94
    • 33845964997 scopus 로고    scopus 로고
    • Effects of muscle strength training and megestrol acetate on strength, muscle mass, and function in frail older people
    • Sullivan DH, Roberson PK, Smith ES, Price JA, Bopp MM. Effects of muscle strength training and megestrol acetate on strength, muscle mass, and function in frail older people. J Am Geriatr Soc 2007;55:20-28.
    • (2007) J Am Geriatr Soc , vol.55 , pp. 20-28
    • Sullivan, D.H.1    Roberson, P.K.2    Smith, E.S.3    Price, J.A.4    Bopp, M.M.5
  • 96
    • 79551496279 scopus 로고    scopus 로고
    • Regular multicomponent exercise increases physical fitness and muscle protein anabolism in frail, obese, older adults
    • Villareal DT, Smith GI, Sinacore DR, Shah K, Mittendorfer B. Regular multicomponent exercise increases physical fitness and muscle protein anabolism in frail, obese, older adults. Obesity (Silver Spring) 2011;19:312-318.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 312-318
    • Villareal, D.T.1    Smith, G.I.2    Sinacore, D.R.3    Shah, K.4    Mittendorfer, B.5
  • 97
    • 0346750736 scopus 로고    scopus 로고
    • The effect of group exercise on physical functioning and falls in frail older people living in retirement villages: A randomized, controlled trial
    • Lord SR, Castell S, Corcoran J, Dayhew J, Matters B, Shan A, Williams P. The effect of group exercise on physical functioning and falls in frail older people living in retirement villages: A randomized, controlled trial. J Am Geriatr Soc 2003;51:1685-1692.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 1685-1692
    • Lord, S.R.1    Castell, S.2    Corcoran, J.3    Dayhew, J.4    Matters, B.5    Shan, A.6    Williams, P.7
  • 99
    • 83855162141 scopus 로고    scopus 로고
    • Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: A meta-analysis
    • De Vries NM, Van Ravensberg CD, Hobbelen JS, Olde Rikkert MG, Staal JB, Nijhuis-van Der Sanden MW. Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: A meta-analysis. Ageing Res Rev 2012;11:136-149.
    • (2012) Ageing Res Rev , vol.11 , pp. 136-149
    • De Vries, N.M.1    Van Ravensberg, C.D.2    Hobbelen, J.S.3    Olde Rikkert, M.G.4    Staal, J.B.5    Nijhuis-van Der Sanden, M.W.6
  • 100
    • 0035986085 scopus 로고    scopus 로고
    • Invited review: Intracellular signaling in contracting skeletal muscle
    • Sakamoto K, Goodyear LJ. Invited review: Intracellular signaling in contracting skeletal muscle. J Appl Physiol 2002;93:369-383.
    • (2002) J Appl Physiol , vol.93 , pp. 369-383
    • Sakamoto, K.1    Goodyear, L.J.2
  • 101
    • 5044227528 scopus 로고    scopus 로고
    • Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle
    • Ji LL, Gomez-Cabrera MC, Steinhafel N, Vina J. Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle. FASEB J 2004;18:1499-1506.
    • (2004) FASEB J , vol.18 , pp. 1499-1506
    • Ji, L.L.1    Gomez-Cabrera, M.C.2    Steinhafel, N.3    Vina, J.4
  • 103
    • 84873378527 scopus 로고    scopus 로고
    • Exercise metabolism and the molecular regulation of skeletal muscle adaptation
    • Egan B, Zierath JR. Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab 2013;17:162-184.
    • (2013) Cell Metab , vol.17 , pp. 162-184
    • Egan, B.1    Zierath, J.R.2
  • 104
    • 0037322888 scopus 로고    scopus 로고
    • Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle
    • Pilegaard H, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 2003;546:851-858.
    • (2003) J Physiol , vol.546 , pp. 851-858
    • Pilegaard, H.1    Saltin, B.2    Neufer, P.D.3
  • 105
    • 24644478044 scopus 로고    scopus 로고
    • Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
    • Mahoney DJ, Parise G, Melov S, Safdar A, Tarnopolsky MA. Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. FASEB J 2005;19:1498-1500.
    • (2005) FASEB J , vol.19 , pp. 1498-1500
    • Mahoney, D.J.1    Parise, G.2    Melov, S.3    Safdar, A.4    Tarnopolsky, M.A.5
  • 107
    • 35648972666 scopus 로고    scopus 로고
    • Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle
    • Louis E, Raue U, Yang Y, Jemiolo B, Trappe S. Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle. J Appl Physiol 2007;103:1744-1751.
    • (2007) J Appl Physiol , vol.103 , pp. 1744-1751
    • Louis, E.1    Raue, U.2    Yang, Y.3    Jemiolo, B.4    Trappe, S.5
  • 108
    • 72549083582 scopus 로고    scopus 로고
    • Exerciseinduced histone modifications in human skeletal muscle
    • McGee SL, Fairlie E, Garnham AP, Hargreaves M. Exerciseinduced histone modifications in human skeletal muscle. J Physiol 2009;587:5951-5958.
    • (2009) J Physiol , vol.587 , pp. 5951-5958
    • McGee, S.L.1    Fairlie, E.2    Garnham, A.P.3    Hargreaves, M.4
  • 110
    • 33846992686 scopus 로고    scopus 로고
    • Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression
    • Wright DC, Han DH, Garcia-Roves PM, Geiger PC, Jones TE, Holloszy JO. Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression. J Biol Chem 2007;282:194-199.
    • (2007) J Biol Chem , vol.282 , pp. 194-199
    • Wright, D.C.1    Han, D.H.2    Garcia-Roves, P.M.3    Geiger, P.C.4    Jones, T.E.5    Holloszy, J.O.6
  • 112
    • 0033939421 scopus 로고    scopus 로고
    • Calcium ion in skeletal muscle: Its crucial role for muscle function, plasticity, and disease
    • Berchtold MW, Brinkmeier H, Muntener M. Calcium ion in skeletal muscle: Its crucial role for muscle function, plasticity, and disease. Physiol Rev 2000;80:1215-1265.
    • (2000) Physiol Rev , vol.80 , pp. 1215-1265
    • Berchtold, M.W.1    Brinkmeier, H.2    Muntener, M.3
  • 113
    • 0842288475 scopus 로고    scopus 로고
    • Ca2 + and AMPK both mediate stimulation of glucose transport by muscle contractions
    • Wright DC, Hucker KA, Holloszy JO, Han DH. Ca2 + and AMPK both mediate stimulation of glucose transport by muscle contractions. Diabetes 2004;53:330-335.
    • (2004) Diabetes , vol.53 , pp. 330-335
    • Wright, D.C.1    Hucker, K.A.2    Holloszy, J.O.3    Han, D.H.4
  • 114
    • 45149088263 scopus 로고    scopus 로고
    • Evidence for the involvement of CaMKII and AMPK in Ca2+ -dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle
    • Raney MA, Turcotte LP. Evidence for the involvement of CaMKII and AMPK in Ca2+ -dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle. J Appl Physiol 2008;104:1366-1373.
    • (2008) J Appl Physiol , vol.104 , pp. 1366-1373
    • Raney, M.A.1    Turcotte, L.P.2
  • 116
    • 0029745782 scopus 로고    scopus 로고
    • Effects of exercise and insulin on mitogenactivated protein kinase signaling pathways in rat skeletal muscle
    • Goodyear LJ, Chang PY, Sherwood DJ, Dufresne SD, Moller DE. Effects of exercise and insulin on mitogenactivated protein kinase signaling pathways in rat skeletal muscle. Am J Physiol 1996;271:E403-E408.
    • (1996) Am J Physiol , vol.271 , pp. E403-E408
    • Goodyear, L.J.1    Chang, P.Y.2    Sherwood, D.J.3    Dufresne, S.D.4    Moller, D.E.5
  • 117
    • 23844540597 scopus 로고    scopus 로고
    • Decreasing xanthine oxidase mediated oxidative stress prevents useful cellular adaptations to exercise in rats
    • Gomez-Cabrera MC, Borras C, Pallardo FV, Sastre J, Ji LL, Vina J. Decreasing xanthine oxidase mediated oxidative stress prevents useful cellular adaptations to exercise in rats. J Physiol 2005;567(Pt 1):113-120.
    • (2005) J Physiol , vol.567 , pp. 113-120
    • Gomez-Cabrera, M.C.1    Borras, C.2    Pallardo, F.V.3    Sastre, J.4    Ji, L.L.5    Vina, J.6
  • 118
    • 21244477127 scopus 로고    scopus 로고
    • Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway
    • Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS, Yan Z. Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem 2005;280:19587-19593.
    • (2005) J Biol Chem , vol.280 , pp. 19587-19593
    • Akimoto, T.1    Pohnert, S.C.2    Li, P.3    Zhang, M.4    Gumbs, C.5    Rosenberg, P.B.6    Williams, R.S.7    Yan, Z.8
  • 119
    • 2942746692 scopus 로고    scopus 로고
    • Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle
    • Long YC, Widegren U, Zierath JR. Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle. Proc Nutr Soc 2004;63:227-232.
    • (2004) Proc Nutr Soc , vol.63 , pp. 227-232
    • Long, Y.C.1    Widegren, U.2    Zierath, J.R.3
  • 120
    • 0020660520 scopus 로고
    • Endurance training reduces the susceptibility of mouse skeletal muscle to lipid peroxidation in vitro
    • Salminen A, Vihko V. Endurance training reduces the susceptibility of mouse skeletal muscle to lipid peroxidation in vitro. Acta Physiol Scand 1983;117:109-113.
    • (1983) Acta Physiol Scand , vol.117 , pp. 109-113
    • Salminen, A.1    Vihko, V.2
  • 121
    • 37849021505 scopus 로고    scopus 로고
    • Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training
    • Gomez-Cabrera MC, Domenech E, Vina J. Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training. Free Radic Biol Med 2008;44:126-131.
    • (2008) Free Radic Biol Med , vol.44 , pp. 126-131
    • Gomez-Cabrera, M.C.1    Domenech, E.2    Vina, J.3
  • 122
    • 74049129489 scopus 로고    scopus 로고
    • Reactive oxygen species are signalling molecules for skeletal muscle adaptation
    • Powers SK, Duarte J, Kavazis AN, Talbert EE. Reactive oxygen species are signalling molecules for skeletal muscle adaptation. Exp Physiol 2010;95:1-9.
    • (2010) Exp Physiol , vol.95 , pp. 1-9
    • Powers, S.K.1    Duarte, J.2    Kavazis, A.N.3    Talbert, E.E.4
  • 124
    • 84864283300 scopus 로고    scopus 로고
    • Muscles, exercise and obesity: Skeletal muscle as a secretory organ
    • Pedersen BK, Febbraio MA. Muscles, exercise and obesity: Skeletal muscle as a secretory organ. Nat Rev Endocrinol 2012;8:457-465.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 457-465
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 126
    • 0024335432 scopus 로고
    • The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase
    • Carling D, Hardie DG. The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase. Biochim Biophys Acta 1989;1012:81-86.
    • (1989) Biochim Biophys Acta , vol.1012 , pp. 81-86
    • Carling, D.1    Hardie, D.G.2
  • 128
    • 34547545892 scopus 로고    scopus 로고
    • AMPactivated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager S, Handschin C, St-Pierre J, Spiegelman BM. AMPactivated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci USA 2007;104:12017-12022.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 129
    • 20844451123 scopus 로고    scopus 로고
    • AMPactivated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn BB, Alquier T, Carling D, Hardie DG. AMPactivated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005;1:15-25.
    • (2005) Cell Metab , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 131
    • 84889681863 scopus 로고    scopus 로고
    • Sestrins orchestrate cellular metabolism to attenuate aging
    • Lee JH, Budanov AV, Karin M. Sestrins orchestrate cellular metabolism to attenuate aging. Cell Metab 2013;18:792-801.
    • (2013) Cell Metab , vol.18 , pp. 792-801
    • Lee, J.H.1    Budanov, A.V.2    Karin, M.3
  • 132
    • 84876726226 scopus 로고    scopus 로고
    • Sestrins: Novel antioxidant and AMPK-modulating functions regulated by exercise?
    • Sanchis-Gomar F. Sestrins: Novel antioxidant and AMPK-modulating functions regulated by exercise? J Cell Physiol 2013;228:1647-1650.
    • (2013) J Cell Physiol , vol.228 , pp. 1647-1650
    • Sanchis-Gomar, F.1
  • 133
    • 38649123072 scopus 로고    scopus 로고
    • Conserved metabolic regulatory functions of sirtuins
    • Schwer B, Verdin E. Conserved metabolic regulatory functions of sirtuins. Cell Metab 2008;7:104-112.
    • (2008) Cell Metab , vol.7 , pp. 104-112
    • Schwer, B.1    Verdin, E.2
  • 137
    • 49049083353 scopus 로고    scopus 로고
    • Signaling in muscle atrophy and hypertrophy
    • Sandri M. Signaling in muscle atrophy and hypertrophy. Physiology (Bethesda). 2008;23:160-170.
    • (2008) Physiology (Bethesda) , vol.23 , pp. 160-170
    • Sandri, M.1
  • 138
  • 140
    • 48549107440 scopus 로고    scopus 로고
    • Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
    • Wilkinson SB, Phillips SM, Atherton PJ, Patel R, Yarasheski KE, Tarnopolsky MA, Rennie MJ. Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol 2008;586:3701-3717.
    • (2008) J Physiol , vol.586 , pp. 3701-3717
    • Wilkinson, S.B.1    Phillips, S.M.2    Atherton, P.J.3    Patel, R.4    Yarasheski, K.E.5    Tarnopolsky, M.A.6    Rennie, M.J.7
  • 141
    • 79851497642 scopus 로고    scopus 로고
    • Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1
    • Philp A, Hamilton DL, Baar K. Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1. J Appl Physiol 2011;110:561-568.
    • (2011) J Appl Physiol , vol.110 , pp. 561-568
    • Philp, A.1    Hamilton, D.L.2    Baar, K.3
  • 142
    • 29944442461 scopus 로고    scopus 로고
    • Endurance training modulates the muscular transcriptome response to acute exercise
    • Schmutz S, Dapp C, Wittwer M, Vogt M, Hoppeler H, Fluck M. Endurance training modulates the muscular transcriptome response to acute exercise. Pflugers Arch 2006;451:678-687.
    • (2006) Pflugers Arch , vol.451 , pp. 678-687
    • Schmutz, S.1    Dapp, C.2    Wittwer, M.3    Vogt, M.4    Hoppeler, H.5    Fluck, M.6
  • 143
    • 38149059911 scopus 로고    scopus 로고
    • Mitochondria and cellular oxygen sensing in the HIF pathway
    • Taylor CT. Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem J 2008;409:19-26.
    • (2008) Biochem J , vol.409 , pp. 19-26
    • Taylor, C.T.1
  • 144
    • 84904987988 scopus 로고    scopus 로고
    • Exercise, nutrition and the brain
    • Meeusen R. Exercise, nutrition and the brain. Sports Med 2014;44(Suppl 1):S47-S56.
    • (2014) Sports Med , vol.44 , pp. S47-S56
    • Meeusen, R.1
  • 145
    • 84880227576 scopus 로고    scopus 로고
    • Physical activity behavior change in persons with neurologic disorders: Overview and examples from Parkinson disease and multiple sclerosis
    • Ellis T, Motl RW. Physical activity behavior change in persons with neurologic disorders: Overview and examples from Parkinson disease and multiple sclerosis. J Neurol Phys Ther 2013;37:85-90.
    • (2013) J Neurol Phys Ther , vol.37 , pp. 85-90
    • Ellis, T.1    Motl, R.W.2
  • 147
    • 79954537038 scopus 로고    scopus 로고
    • Exercise is beneficial for patients with Alzheimer's disease: A call for action
    • Lucia A, Ruiz JR. Exercise is beneficial for patients with Alzheimer's disease: A call for action. Br J Sports Med 2011;45:468-469.
    • (2011) Br J Sports Med , vol.45 , pp. 468-469
    • Lucia, A.1    Ruiz, J.R.2
  • 151
    • 56349145099 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease: A reappraisal
    • Pratico D. Oxidative stress hypothesis in Alzheimer's disease: A reappraisal. Trends Pharmacol Sci 2008;29:609-615.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 609-615
    • Pratico, D.1
  • 152
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery WR. Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 1997;23:134-147.
    • (1997) Free Radic Biol Med , vol.23 , pp. 134-147
    • Markesbery, W.R.1
  • 154
    • 0028129137 scopus 로고
    • Evidence of an oxidative challenge in the Alzheimer's brain
    • Balazs L, Leon M. Evidence of an oxidative challenge in the Alzheimer's brain. Neurochem Res 1994;19:1131-1137.
    • (1994) Neurochem Res , vol.19 , pp. 1131-1137
    • Balazs, L.1    Leon, M.2
  • 155
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993;262:689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 156
    • 0026643279 scopus 로고
    • Reactive oxygen species: Relation to aging and neurotoxic damage
    • Bondy SC. Reactive oxygen species: Relation to aging and neurotoxic damage. Neurotoxicology 1992;13:87-100.
    • (1992) Neurotoxicology , vol.13 , pp. 87-100
    • Bondy, S.C.1
  • 157
    • 0025981361 scopus 로고
    • Protein, lipid and DNA repair systems in oxidative stress: The free-radical theory of aging revisited
    • Pacifici RE, Davies KJ. Protein, lipid and DNA repair systems in oxidative stress: The free-radical theory of aging revisited. Gerontology 1991;37:166-180.
    • (1991) Gerontology , vol.37 , pp. 166-180
    • Pacifici, R.E.1    Davies, K.J.2
  • 158
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery WR, Carney JM. Oxidative alterations in Alzheimer's disease. Brain Pathol 1999;9:133-146.
    • (1999) Brain Pathol , vol.9 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 159
    • 0030844416 scopus 로고    scopus 로고
    • Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats
    • Hara M, Iigo M, Ohtani-Kaneko R, Nakamura N, Suzuki T, Reiter RJ, Hirata K. Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats. Biol Signals 1997;6:90-100.
    • (1997) Biol Signals , vol.6 , pp. 90-100
    • Hara, M.1    Iigo, M.2    Ohtani-Kaneko, R.3    Nakamura, N.4    Suzuki, T.5    Reiter, R.J.6    Hirata, K.7
  • 160
    • 0028951135 scopus 로고
    • Effect of exercise training on antioxidant system in brain regions of rat
    • Somani SM, Ravi R, Rybak LP. Effect of exercise training on antioxidant system in brain regions of rat. Pharmacol Biochem Behav 1995;50:635-639.
    • (1995) Pharmacol Biochem Behav , vol.50 , pp. 635-639
    • Somani, S.M.1    Ravi, R.2    Rybak, L.P.3
  • 162
    • 77955948750 scopus 로고    scopus 로고
    • Neuroplasticity - Exercise-induced response of peripheral brain-derived neurotrophic factor: A systematic review of experimental studies in human subjects
    • Knaepen K, Goekint M, Heyman EM, Meeusen R. Neuroplasticity - exercise-induced response of peripheral brain-derived neurotrophic factor: A systematic review of experimental studies in human subjects. Sports Med 2010;40:765-801.
    • (2010) Sports Med , vol.40 , pp. 765-801
    • Knaepen, K.1    Goekint, M.2    Heyman, E.M.3    Meeusen, R.4
  • 164
    • 34147095845 scopus 로고    scopus 로고
    • The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function
    • Ferris LT, Williams JS, Shen CL. The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Med Sci Sports Exerc 2007;39:728-734.
    • (2007) Med Sci Sports Exerc , vol.39 , pp. 728-734
    • Ferris, L.T.1    Williams, J.S.2    Shen, C.L.3
  • 165
    • 84866320261 scopus 로고    scopus 로고
    • Kinetics of serum brainderived neurotrophic factor following low-intensity versus high-intensity exercise in men and women
    • Schmidt-Kassow M, Schadle S, Otterbein S, Thiel C, Doehring A, Lotsch J, Kaiser J. Kinetics of serum brainderived neurotrophic factor following low-intensity versus high-intensity exercise in men and women. Neuroreport 2012;23:889-893.
    • (2012) Neuroreport , vol.23 , pp. 889-893
    • Schmidt-Kassow, M.1    Schadle, S.2    Otterbein, S.3    Thiel, C.4    Doehring, A.5    Lotsch, J.6    Kaiser, J.7
  • 167
    • 0036602967 scopus 로고    scopus 로고
    • Exercise: A behavioral intervention to enhance brain health and plasticity
    • Cotman CW, Berchtold NC. Exercise: A behavioral intervention to enhance brain health and plasticity. Trends Neurosci 2002;25:295-301.
    • (2002) Trends Neurosci , vol.25 , pp. 295-301
    • Cotman, C.W.1    Berchtold, N.C.2
  • 168
    • 0036850342 scopus 로고    scopus 로고
    • Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity
    • Gomez-Pinilla F, Ying Z, Roy RR, Molteni R, Edgerton VR. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J Neurophysiol 2002;88:2187-2195.
    • (2002) J Neurophysiol , vol.88 , pp. 2187-2195
    • Gomez-Pinilla, F.1    Ying, Z.2    Roy, R.R.3    Molteni, R.4    Edgerton, V.R.5
  • 169
    • 2942685961 scopus 로고    scopus 로고
    • BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury
    • Mousavi K, Parry DJ, Jasmin BJ. BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury. Am J Physiol Cell Physiol 2004;287:C22-C29.
    • (2004) Am J Physiol Cell Physiol , vol.287 , pp. C22-C29
    • Mousavi, K.1    Parry, D.J.2    Jasmin, B.J.3
  • 170
    • 9644270414 scopus 로고    scopus 로고
    • Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
    • Vaynman S, Ying Z, Gomez-Pinilla F. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur J Neurosci 2004;20:2580-2590.
    • (2004) Eur J Neurosci , vol.20 , pp. 2580-2590
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 171
    • 0031036208 scopus 로고    scopus 로고
    • Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein
    • Murphy DD, Segal M. Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein. Proc Natl Acad Sci USA 1997;94:1482-1487.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1482-1487
    • Murphy, D.D.1    Segal, M.2
  • 172
    • 33747627893 scopus 로고    scopus 로고
    • Molecular mechanism of neuronal plasticity: Induction and maintenance of long-term potentiation in the hippocampus
    • Miyamoto E. Molecular mechanism of neuronal plasticity: Induction and maintenance of long-term potentiation in the hippocampus. J Pharmacol Sci. 2006;100:433-442.
    • (2006) J Pharmacol Sci , vol.100 , pp. 433-442
    • Miyamoto, E.1
  • 175
    • 0242653760 scopus 로고    scopus 로고
    • Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity
    • Vaynman S, Ying Z, Gomez-Pinilla F. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience 2003;122:647-657.
    • (2003) Neuroscience , vol.122 , pp. 647-657
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 176
    • 18844460905 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant activity
    • Russo-Neustadt AA, Chen MJ. Brain-derived neurotrophic factor and antidepressant activity. Curr Pharm Des 2005;11:1495-1510.
    • (2005) Curr Pharm Des , vol.11 , pp. 1495-1510
    • Russo-Neustadt, A.A.1    Chen, M.J.2
  • 177
    • 33646819345 scopus 로고    scopus 로고
    • Insulin-like growth factor I interfaces with brainderived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function
    • Ding Q, Vaynman S, Akhavan M, Ying Z, Gomez-Pinilla F. Insulin-like growth factor I interfaces with brainderived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function. Neuroscience 2006;140:823-833.
    • (2006) Neuroscience , vol.140 , pp. 823-833
    • Ding, Q.1    Vaynman, S.2    Akhavan, M.3    Ying, Z.4    Gomez-Pinilla, F.5
  • 179
    • 33748954225 scopus 로고    scopus 로고
    • Insulin-like growth factor-I enhances the biological activity of brain-derived neurotrophic factor on cerebrocortical neurons
    • McCusker RH, McCrea K, Zunich S, Dantzer R, Broussard SR, Johnson RW, Kelley KW. Insulin-like growth factor-I enhances the biological activity of brain-derived neurotrophic factor on cerebrocortical neurons. J Neuroimmunol 2006;179:186-190.
    • (2006) J Neuroimmunol , vol.179 , pp. 186-190
    • McCusker, R.H.1    McCrea, K.2    Zunich, S.3    Dantzer, R.4    Broussard, S.R.5    Johnson, R.W.6    Kelley, K.W.7
  • 181
    • 0010330438 scopus 로고    scopus 로고
    • Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
    • Neeper SA, Gomez-Pinilla F, Choi J, Cotman CW. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res 1996;726:49-56.
    • (1996) Brain Res , vol.726 , pp. 49-56
    • Neeper, S.A.1    Gomez-Pinilla, F.2    Choi, J.3    Cotman, C.W.4
  • 182
    • 84894180246 scopus 로고    scopus 로고
    • Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain
    • Revilla S, Sunol C, Garcia-Mesa Y, Gimenez-Llort L, Sanfeliu C, Cristofol R. Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain. Neuropharmacology 2014;81:55-63.
    • (2014) Neuropharmacology , vol.81 , pp. 55-63
    • Revilla, S.1    Sunol, C.2    Garcia-Mesa, Y.3    Gimenez-Llort, L.4    Sanfeliu, C.5    Cristofol, R.6
  • 183
    • 84886801248 scopus 로고    scopus 로고
    • Spontaneous Wheel running exercise induces brain recovery via neurotrophin-3 expression following experimental traumatic brain injury in rats
    • Koo HM, Lee SM, Kim MH. Spontaneous Wheel running exercise induces brain recovery via neurotrophin-3 expression following experimental traumatic brain injury in rats. J Phys Ther Sci 2013;25:1103-1107.
    • (2013) J Phys Ther Sci , vol.25 , pp. 1103-1107
    • Koo, H.M.1    Lee, S.M.2    Kim, M.H.3
  • 184
    • 84875069592 scopus 로고    scopus 로고
    • Increased expression of neurotrophin 4 following focal cerebral ischemia in adult rat brain with treadmill exercise
    • Chung JY, Kim MW, Bang MS, Kim M. Increased expression of neurotrophin 4 following focal cerebral ischemia in adult rat brain with treadmill exercise. PLoS One 2013;8:e52461.
    • (2013) PLoS One , vol.8 , pp. e52461
    • Chung, J.Y.1    Kim, M.W.2    Bang, M.S.3    Kim, M.4
  • 186
    • 84891701025 scopus 로고    scopus 로고
    • All about running: Synaptic plasticity, growth factors and adult hippocampal neurogenesis
    • Vivar C, Potter MC, Van Praag H. All about running: Synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr Top Behav Neurosci 2013;15:189-210.
    • (2013) Curr Top Behav Neurosci , vol.15 , pp. 189-210
    • Vivar, C.1    Potter, M.C.2    Van Praag, H.3
  • 187
  • 189
    • 84864321286 scopus 로고    scopus 로고
    • BDNF control of adult SVZ neurogenesis
    • Bath KG, Akins MR, Lee FS. BDNF control of adult SVZ neurogenesis. Dev Psychobiol 2012;54:578-589.
    • (2012) Dev Psychobiol , vol.54 , pp. 578-589
    • Bath, K.G.1    Akins, M.R.2    Lee, F.S.3
  • 190
    • 63349097497 scopus 로고    scopus 로고
    • Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis
    • Llorens-Martin M, Torres-Aleman I, Trejo JL. Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis. Neuroscientist 2009;15:134-148.
    • (2009) Neuroscientist , vol.15 , pp. 134-148
    • Llorens-Martin, M.1    Torres-Aleman, I.2    Trejo, J.L.3
  • 193
    • 84878114130 scopus 로고    scopus 로고
    • Tau degradation: The ubiquitin-proteasome system versus the autophagylysosome system
    • Lee MJ, Lee JH, Rubinsztein DC. Tau degradation: The ubiquitin-proteasome system versus the autophagylysosome system. Prog Neurobiol 2013;105:49-59.
    • (2013) Prog Neurobiol , vol.105 , pp. 49-59
    • Lee, M.J.1    Lee, J.H.2    Rubinsztein, D.C.3
  • 195
    • 33646918035 scopus 로고    scopus 로고
    • Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses
    • Karpova A, Mikhaylova M, Thomas U, Knopfel T, Behnisch T. Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses. J Neurosci 2006;26:4949-4955.
    • (2006) J Neurosci , vol.26 , pp. 4949-4955
    • Karpova, A.1    Mikhaylova, M.2    Thomas, U.3    Knopfel, T.4    Behnisch, T.5
  • 199
    • 14844311928 scopus 로고    scopus 로고
    • Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults
    • Parise G, Brose AN, Tarnopolsky MA. Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults. Exp Gerontol 2005;40:173-180.
    • (2005) Exp Gerontol , vol.40 , pp. 173-180
    • Parise, G.1    Brose, A.N.2    Tarnopolsky, M.A.3
  • 200
    • 0036452555 scopus 로고    scopus 로고
    • Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle
    • Radak Z, Naito H, Kaneko T, Tahara S, Nakamoto H, Takahashi R, Cardozo-Pelaez F, Goto S. Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers Archiv 2002;445:273-278.
    • (2002) Pflugers Archiv , vol.445 , pp. 273-278
    • Radak, Z.1    Naito, H.2    Kaneko, T.3    Tahara, S.4    Nakamoto, H.5    Takahashi, R.6    Cardozo-Pelaez, F.7    Goto, S.8
  • 201
    • 77951093550 scopus 로고    scopus 로고
    • PGC-1alpha is required for training-induced prevention of ageassociated decline in mitochondrial enzymes in mouse skeletal muscle
    • Leick L, Lyngby SS, Wojtaszewski JF, Pilegaard H. PGC-1alpha is required for training-induced prevention of ageassociated decline in mitochondrial enzymes in mouse skeletal muscle. Exp Gerontol 2010;45:336-342.
    • (2010) Exp Gerontol , vol.45 , pp. 336-342
    • Leick, L.1    Lyngby, S.S.2    Wojtaszewski, J.F.3    Pilegaard, H.4
  • 202
  • 203
    • 0035256310 scopus 로고    scopus 로고
    • Telomere length as an indicator of biological aging: The gender effect and relation with pulse pressure and pulse wave velocity
    • Benetos A, Okuda K, Lajemi M, Kimura M, Thomas F, Skurnick J, Labat C, Bean K, Aviv A. Telomere length as an indicator of biological aging: The gender effect and relation with pulse pressure and pulse wave velocity. Hypertension 2001;37:381-385.
    • (2001) Hypertension , vol.37 , pp. 381-385
    • Benetos, A.1    Okuda, K.2    Lajemi, M.3    Kimura, M.4    Thomas, F.5    Skurnick, J.6    Labat, C.7    Bean, K.8    Aviv, A.9
  • 207
    • 1242272818 scopus 로고    scopus 로고
    • Telomere length and possible link to X chromosome
    • Nawrot TS, Staessen JA, Gardner JP, Aviv A. Telomere length and possible link to X chromosome. Lancet 2004;363:507-510.
    • (2004) Lancet , vol.363 , pp. 507-510
    • Nawrot, T.S.1    Staessen, J.A.2    Gardner, J.P.3    Aviv, A.4
  • 213
    • 77249132506 scopus 로고    scopus 로고
    • Leukocyte telomere length is preserved with aging in endurance exercisetrained adults and related to maximal aerobic capacity
    • La Rocca TJ, Seals DR, Pierce GL. Leukocyte telomere length is preserved with aging in endurance exercisetrained adults and related to maximal aerobic capacity. Mech Ageing Dev 2010;131:165-167.
    • (2010) Mech Ageing Dev , vol.131 , pp. 165-167
    • La Rocca, T.J.1    Seals, D.R.2    Pierce, G.L.3
  • 215
    • 77955845440 scopus 로고    scopus 로고
    • The power of exercise: Buffering the effect of chronic stress on telomere length
    • Puterman E, Lin J, Blackburn E, O'Donovan A, Adler N, Epel E. The power of exercise: Buffering the effect of chronic stress on telomere length. PLoS One 2010;5:e10837.
    • (2010) PLoS One , vol.5 , pp. e10837
    • Puterman, E.1    Lin, J.2    Blackburn, E.3    O'Donovan, A.4    Adler, N.5    Epel, E.6
  • 217
    • 84859560875 scopus 로고    scopus 로고
    • Increased shelterin mRNA expression in peripheral blood mononuclear cells and skeletal muscle following an ultra-long-distance running event
    • Laye MJ, Solomon TP, Karstoft K, Pedersen KK, Nielsen SD, Pedersen BK. Increased shelterin mRNA expression in peripheral blood mononuclear cells and skeletal muscle following an ultra-long-distance running event. J Appl Physiol 2012;112:773-781.
    • (2012) J Appl Physiol , vol.112 , pp. 773-781
    • Laye, M.J.1    Solomon, T.P.2    Karstoft, K.3    Pedersen, K.K.4    Nielsen, S.D.5    Pedersen, B.K.6
  • 220
  • 222
    • 38449105997 scopus 로고    scopus 로고
    • The aging process and potential interventions to extend life expectancy
    • Tosato M, Zamboni V, Ferrini A, Cesari M. The aging process and potential interventions to extend life expectancy. Clin Interv Aging 2007;2:401-412.
    • (2007) Clin Interv Aging , vol.2 , pp. 401-412
    • Tosato, M.1    Zamboni, V.2    Ferrini, A.3    Cesari, M.4
  • 223
    • 84855305520 scopus 로고    scopus 로고
    • Physical activity and telomere biology: Exploring the link with aging-related disease prevention
    • Ludlow AT, Roth SM. Physical activity and telomere biology: Exploring the link with aging-related disease prevention. J Aging Res 2011;2011:790378.
    • (2011) J Aging Res , vol.2011 , pp. 790378
    • Ludlow, A.T.1    Roth, S.M.2
  • 226
    • 84897471315 scopus 로고    scopus 로고
    • Physical exercise and epigenetic modulation: Elucidating intricate mechanisms
    • Pareja-Galeano H, Sanchis-Gomar F, Garcia-Gimenez JL. Physical exercise and epigenetic modulation: Elucidating intricate mechanisms. Sports Med 2014;44:429-436.
    • (2014) Sports Med , vol.44 , pp. 429-436
    • Pareja-Galeano, H.1    Sanchis-Gomar, F.2    Garcia-Gimenez, J.L.3
  • 227
    • 84903786303 scopus 로고    scopus 로고
    • Epigenetic adaptation to regular exercise in humans
    • Ling C, Ronn T. Epigenetic adaptation to regular exercise in humans. Drug Discov Today 2014; doi:10.1016/j.drudis. 2014.03.006.
    • (2014) Drug Discov Today
    • Ling, C.1    Ronn, T.2
  • 229
    • 79957567315 scopus 로고    scopus 로고
    • Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia
    • Wolf SA, Melnik A, Kempermann G. Physical exercise increases adult neurogenesis and telomerase activity, and improves behavioral deficits in a mouse model of schizophrenia. Brain Behav Immun 2011;25:971-980.
    • (2011) Brain Behav Immun , vol.25 , pp. 971-980
    • Wolf, S.A.1    Melnik, A.2    Kempermann, G.3
  • 231
    • 78649710608 scopus 로고    scopus 로고
    • Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle
    • Perry CG, Lally J, Holloway GP, Heigenhauser GJ, Bonen A, Spriet LL. Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle. J Physiol 2010;588:4795-4810.
    • (2010) J Physiol , vol.588 , pp. 4795-4810
    • Perry, C.G.1    Lally, J.2    Holloway, G.P.3    Heigenhauser, G.J.4    Bonen, A.5    Spriet, L.L.6
  • 232
    • 0021343295 scopus 로고
    • Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
    • Holloszy JO, Coyle EF. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 1984;56:831-838.
    • (1984) J Appl Physiol , vol.56 , pp. 831-838
    • Holloszy, J.O.1    Coyle, E.F.2
  • 233
    • 0025782887 scopus 로고
    • Molecular and cellular adaptation of muscle in response to exercise: Perspectives of various models
    • Booth FW, Thomason DB. Molecular and cellular adaptation of muscle in response to exercise: Perspectives of various models. Physiol Rev 1991;71:541-585.
    • (1991) Physiol Rev , vol.71 , pp. 541-585
    • Booth, F.W.1    Thomason, D.B.2
  • 234
    • 84903758478 scopus 로고    scopus 로고
    • Dynamic epigenetic responses to muscle contraction
    • Rasmussen M, Zierath JR, Barres R. Dynamic epigenetic responses to muscle contraction. Drug Discov Today 2014;19:1010-1014.
    • (2014) Drug Discov Today , vol.19 , pp. 1010-1014
    • Rasmussen, M.1    Zierath, J.R.2    Barres, R.3
  • 237
    • 84876458561 scopus 로고    scopus 로고
    • Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets
    • Dayeh TA, Olsson AH, Volkov P, Almgren P, Ronn T, Ling C. Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets. Diabetologia 2013;56:1036-1046.
    • (2013) Diabetologia , vol.56 , pp. 1036-1046
    • Dayeh, T.A.1    Olsson, A.H.2    Volkov, P.3    Almgren, P.4    Ronn, T.5    Ling, C.6
  • 244
    • 33745813868 scopus 로고    scopus 로고
    • Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women
    • Raue U, Slivka D, Jemiolo B, Hollon C, Trappe S. Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women. J Appl Physiol 2006;101:53-59.
    • (2006) J Appl Physiol , vol.101 , pp. 53-59
    • Raue, U.1    Slivka, D.2    Jemiolo, B.3    Hollon, C.4    Trappe, S.5
  • 245
    • 79251578642 scopus 로고    scopus 로고
    • Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation
    • Gomez-Pinilla F, Zhuang Y, Feng J, Ying Z, Fan G. Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation. Eur J Neurosci 2011;33:383-390.
    • (2011) Eur J Neurosci , vol.33 , pp. 383-390
    • Gomez-Pinilla, F.1    Zhuang, Y.2    Feng, J.3    Ying, Z.4    Fan, G.5
  • 246
    • 79251498807 scopus 로고    scopus 로고
    • Protein homeostasis and aging: The importance of exquisite quality control
    • Koga H, Kaushik S, Cuervo AM. Protein homeostasis and aging: The importance of exquisite quality control. Ageing Res Rev 2010;10:205-215.
    • (2010) Ageing Res Rev , vol.10 , pp. 205-215
    • Koga, H.1    Kaushik, S.2    Cuervo, A.M.3
  • 250
    • 79956095420 scopus 로고    scopus 로고
    • Autophagosome formation and molecular mechanism of autophagy
    • Tanida I. Autophagosome formation and molecular mechanism of autophagy. Antioxid Redox Signal 2010;14:2201-2214.
    • (2010) Antioxid Redox Signal , vol.14 , pp. 2201-2214
    • Tanida, I.1
  • 251
    • 84867249241 scopus 로고    scopus 로고
    • Exercise induces autophagy in peripheral tissues and in the brain
    • He C, Sumpter R, Jr., Levine B. Exercise induces autophagy in peripheral tissues and in the brain. Autophagy 2012;8:1548-1551.
    • (2012) Autophagy , vol.8 , pp. 1548-1551
    • He, C.1    Sumpter, R.2    Levine, B.3
  • 253
    • 84888428419 scopus 로고    scopus 로고
    • Autophagic response to exercise training in skeletal muscle with age
    • Kim YA, Kim YS, Oh SL, Kim HJ, Song W. Autophagic response to exercise training in skeletal muscle with age. J Physiol Biochem 2013;69:697-705.
    • (2013) J Physiol Biochem , vol.69 , pp. 697-705
    • Kim, Y.A.1    Kim, Y.S.2    Oh, S.L.3    Kim, H.J.4    Song, W.5
  • 254
    • 84874765168 scopus 로고    scopus 로고
    • Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats
    • Luo L, Lu AM, Wang Y, Hong A, Chen Y, Hu J, Li X, Qin ZH. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Exp Gerontol 2013;48:427-436.
    • (2013) Exp Gerontol , vol.48 , pp. 427-436
    • Luo, L.1    Lu, A.M.2    Wang, Y.3    Hong, A.4    Chen, Y.5    Hu, J.6    Li, X.7    Qin, Z.H.8
  • 259
    • 84918818926 scopus 로고    scopus 로고
    • Can enhanced autophagy be associated with human longevity? Serum levels of the autophagy biomarker beclin-1 are increased in healthy centenarians
    • Emanuele E, Minoretti P, Sanchis-Gomar F, Pareja-Galeano H, Yilmaz Y, Garatachea N, Lucia A. Can enhanced autophagy be associated with human longevity? Serum levels of the autophagy biomarker beclin-1 are increased in healthy centenarians. Rejuvenation Res 2014;17:518-524.
    • (2014) Rejuvenation Res , vol.17 , pp. 518-524
    • Emanuele, E.1    Minoretti, P.2    Sanchis-Gomar, F.3    Pareja-Galeano, H.4    Yilmaz, Y.5    Garatachea, N.6    Lucia, A.7
  • 261
    • 75049085555 scopus 로고    scopus 로고
    • Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
    • Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise. Exp Gerontol 2010;45:138-148.
    • (2010) Exp Gerontol , vol.45 , pp. 138-148
    • Wohlgemuth, S.E.1    Seo, A.Y.2    Marzetti, E.3    Lees, H.A.4    Leeuwenburgh, C.5
  • 265
    • 77649178910 scopus 로고    scopus 로고
    • Effect of physical training on agerelated reduction of GH secretion during exercise in normally cycling women
    • Coiro V, Volpi R, Gramellini D, Maffei ML, Volta E, Melani A, Chiodera P. Effect of physical training on agerelated reduction of GH secretion during exercise in normally cycling women. Maturitas 2010;65:392-395.
    • (2010) Maturitas , vol.65 , pp. 392-395
    • Coiro, V.1    Volpi, R.2    Gramellini, D.3    Maffei, M.L.4    Volta, E.5    Melani, A.6    Chiodera, P.7
  • 266
    • 34249678700 scopus 로고    scopus 로고
    • Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
    • Fujita S, Rasmussen BB, Cadenas JG, Drummond MJ, Glynn EL, Sattler FR, Volpi E. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes 2007;56:1615-1622.
    • (2007) Diabetes , vol.56 , pp. 1615-1622
    • Fujita, S.1    Rasmussen, B.B.2    Cadenas, J.G.3    Drummond, M.J.4    Glynn, E.L.5    Sattler, F.R.6    Volpi, E.7
  • 267
    • 72749098121 scopus 로고    scopus 로고
    • Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
    • Mayhew DL, Kim JS, Cross JM, Ferrando AA, Bamman MM. Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans. J Appl Physiol 2009;107:1655-1662.
    • (2009) J Appl Physiol , vol.107 , pp. 1655-1662
    • Mayhew, D.L.1    Kim, J.S.2    Cross, J.M.3    Ferrando, A.A.4    Bamman, M.M.5
  • 268
    • 84864348386 scopus 로고    scopus 로고
    • Exercise and amino acid anabolic cell signaling and the regulation of skeletal muscle mass
    • Pasiakos SM. Exercise and amino acid anabolic cell signaling and the regulation of skeletal muscle mass. Nutrients 2012;4:740-758.
    • (2012) Nutrients , vol.4 , pp. 740-758
    • Pasiakos, S.M.1
  • 272
    • 0023227784 scopus 로고
    • Physiologic responses to heavy-resistance exercise with very short rest periods
    • Kraemer WJ, Noble BJ, Clark MJ, Culver BW. Physiologic responses to heavy-resistance exercise with very short rest periods. Int J Sports Med 1987;8:247-252.
    • (1987) Int J Sports Med , vol.8 , pp. 247-252
    • Kraemer, W.J.1    Noble, B.J.2    Clark, M.J.3    Culver, B.W.4
  • 273
    • 17844384537 scopus 로고    scopus 로고
    • Hormonal responses and adaptations to resistance exercise and training
    • Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med 2005;35:339-361.
    • (2005) Sports Med , vol.35 , pp. 339-361
    • Kraemer, W.J.1    Ratamess, N.A.2
  • 275
    • 33846032621 scopus 로고    scopus 로고
    • Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young males
    • Hartman JW, Moore DR, Phillips SM. Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young males. Appl Physiol Nutr Metab 2006;31:557-564.
    • (2006) Appl Physiol Nutr Metab , vol.31 , pp. 557-564
    • Hartman, J.W.1    Moore, D.R.2    Phillips, S.M.3
  • 276
    • 0027202154 scopus 로고
    • Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women
    • Yarasheski KE, Zachwieja JJ, Bier DM. Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women. Am J Physiol 1993;265:E210-E214.
    • (1993) Am J Physiol , vol.265 , pp. E210-E214
    • Yarasheski, K.E.1    Zachwieja, J.J.2    Bier, D.M.3
  • 277
    • 0032768450 scopus 로고    scopus 로고
    • Resistance exercise training increases mixed muscle protein synthesis rate in frail women and men >/= 76 yr old
    • Yarasheski KE, Pak-Loduca J, Hasten DL, Obert KA, Brown MB, Sinacore DR. Resistance exercise training increases mixed muscle protein synthesis rate in frail women and men >/= 76 yr old. Am J Physiol 1999;277:E118-E125.
    • (1999) Am J Physiol , vol.277 , pp. E118-E125
    • Yarasheski, K.E.1    Pak-Loduca, J.2    Hasten, D.L.3    Obert, K.A.4    Brown, M.B.5    Sinacore, D.R.6
  • 278
    • 0035881047 scopus 로고    scopus 로고
    • Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans
    • Esmarck B, Andersen JL, Olsen S, Richter EA, Mizuno M, Kjaer M. Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans. J Physiol 2001;535:301-311.
    • (2001) J Physiol , vol.535 , pp. 301-311
    • Esmarck, B.1    Andersen, J.L.2    Olsen, S.3    Richter, E.A.4    Mizuno, M.5    Kjaer, M.6
  • 279
    • 33746691931 scopus 로고    scopus 로고
    • Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs older adults
    • Kosek DJ, Kim JS, Petrella JK, Cross JM, Bamman MM. Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults. J Appl Physiol 2006;101:531-544.
    • (2006) J Appl Physiol , vol.101 , pp. 531-544
    • Kosek, D.J.1    Kim, J.S.2    Petrella, J.K.3    Cross, J.M.4    Bamman, M.M.5
  • 281
    • 0028913909 scopus 로고
    • Myofibrillar protein synthesis in young and old human subjects after three months of resistance training
    • Welle S, Thornton C, Statt M. Myofibrillar protein synthesis in young and old human subjects after three months of resistance training. Am J Physiol 1995;268:E422-E427.
    • (1995) Am J Physiol , vol.268 , pp. E422-E427
    • Welle, S.1    Thornton, C.2    Statt, M.3
  • 282
    • 0019270789 scopus 로고
    • Isometric and isokinetic quadriceps muscle strength in 70-year-old men and women
    • Aniansson A, Grimby G, Rundgren A. Isometric and isokinetic quadriceps muscle strength in 70-year-old men and women. Scand J Rehabil Med 1980;12:161-168.
    • (1980) Scand J Rehabil Med , vol.12 , pp. 161-168
    • Aniansson, A.1    Grimby, G.2    Rundgren, A.3
  • 284
    • 0025674177 scopus 로고
    • Detection of a specific mitochondrial DNA deletion in tissues of older humans
    • Cortopassi GA, Arnheim N. Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res 1990;18:6927-6933.
    • (1990) Nucleic Acids Res , vol.18 , pp. 6927-6933
    • Cortopassi, G.A.1    Arnheim, N.2
  • 285
    • 0026732706 scopus 로고
    • A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
    • Cortopassi GA, Shibata D, Soong NW, Arnheim N. A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci USA 1992;89:7370-7374.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7370-7374
    • Cortopassi, G.A.1    Shibata, D.2    Soong, N.W.3    Arnheim, N.4
  • 288
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: A theory based on free radical and radiation chemistry. J Gerontol 1956;11:298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 289
    • 77956181349 scopus 로고    scopus 로고
    • Mitochondrial DNA alterations and reduced mitochondrial function in aging
    • Hebert SL, Lanza IR, Nair KS. Mitochondrial DNA alterations and reduced mitochondrial function in aging. Mech Ageing Dev 2010;131:451-462.
    • (2010) Mech Ageing Dev , vol.131 , pp. 451-462
    • Hebert, S.L.1    Lanza, I.R.2    Nair, K.S.3
  • 292
    • 0030451773 scopus 로고    scopus 로고
    • Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle
    • Rooyackers OE, Adey DB, Ades PA, Nair KS. Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA 1996;93:15364-15369.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15364-15369
    • Rooyackers, O.E.1    Adey, D.B.2    Ades, P.A.3    Nair, K.S.4
  • 293
    • 0033942574 scopus 로고    scopus 로고
    • High-abundance mRNAs in human muscle: Comparison between young and old
    • Welle S, Bhatt K, Thornton CA. High-abundance mRNAs in human muscle: Comparison between young and old. J Appl Physiol 2000;89:297-304.
    • (2000) J Appl Physiol , vol.89 , pp. 297-304
    • Welle, S.1    Bhatt, K.2    Thornton, C.A.3
  • 296
    • 0031885843 scopus 로고    scopus 로고
    • Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
    • Brierley EJ, Johnson MA, Lightowlers RN, James OF, Turnbull DM. Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle. Ann Neurol 1998;43:217-223.
    • (1998) Ann Neurol , vol.43 , pp. 217-223
    • Brierley, E.J.1    Johnson, M.A.2    Lightowlers, R.N.3    James, O.F.4    Turnbull, D.M.5
  • 297
    • 33748643416 scopus 로고    scopus 로고
    • Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers
    • Bua E, Johnson J, Herbst A, Delong B, McKenzie D, Salamat S, Aiken JM. Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers. Am J Hum Genet 2006;79:469-480.
    • (2006) Am J Hum Genet , vol.79 , pp. 469-480
    • Bua, E.1    Johnson, J.2    Herbst, A.3    Delong, B.4    McKenzie, D.5    Salamat, S.6    Aiken, J.M.7
  • 298
    • 0036089622 scopus 로고    scopus 로고
    • Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia
    • Bua EA, McKiernan SH, Wanagat J, McKenzie D, Aiken JM. Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia. J Appl Physiol 2002;92:2617-2624.
    • (2002) J Appl Physiol , vol.92 , pp. 2617-2624
    • Bua, E.A.1    McKiernan, S.H.2    Wanagat, J.3    McKenzie, D.4    Aiken, J.M.5
  • 299
    • 67651231036 scopus 로고    scopus 로고
    • Mitochondrial DNA shifting in older adults following resistance exercise training
    • Tarnopolsky MA. Mitochondrial DNA shifting in older adults following resistance exercise training. Appl Physiol Nutr Metabolism 2009;34:348-354.
    • (2009) Appl Physiol Nutr Metabolism , vol.34 , pp. 348-354
    • Tarnopolsky, M.A.1
  • 301
    • 0021906677 scopus 로고
    • Influences of endurance training on the ultrastructural composition of the different muscle fiber types in humans
    • Howald H, Hoppeler H, Claassen H, Mathieu O, Straub R. Influences of endurance training on the ultrastructural composition of the different muscle fiber types in humans. Pflugers Arch 1985;403:369-376.
    • (1985) Pflugers Arch , vol.403 , pp. 369-376
    • Howald, H.1    Hoppeler, H.2    Claassen, H.3    Mathieu, O.4    Straub, R.5
  • 302
    • 77957962904 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor-an exercise-induced myokine
    • Broholm C, Pedersen BK. Leukaemia inhibitory factor-an exercise-induced myokine. Exercise Immunol Rev 2010;16:77-85.
    • (2010) Exercise Immunol Rev , vol.16 , pp. 77-85
    • Broholm, C.1    Pedersen, B.K.2
  • 303
    • 84881186271 scopus 로고    scopus 로고
    • Can exercise-related improvements in immunity influence cancer prevention and prognosis in the elderly?
    • Bigley AB, Spielmann G, La Voy EC, Simpson RJ. Can exercise-related improvements in immunity influence cancer prevention and prognosis in the elderly? Maturitas 2013;76:51-56.
    • (2013) Maturitas , vol.76 , pp. 51-56
    • Bigley, A.B.1    Spielmann, G.2    La Voy, E.C.3    Simpson, R.J.4
  • 304
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 1996;93:13742-13747.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5    Barrett, J.C.6
  • 305
    • 0033013980 scopus 로고    scopus 로고
    • Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
    • Stein GH, Drullinger LF, Soulard A, Dulic V. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts. Mol Cell Biol 1999;19:2109-2117.
    • (1999) Mol Cell Biol , vol.19 , pp. 2109-2117
    • Stein, G.H.1    Drullinger, L.F.2    Soulard, A.3    Dulic, V.4
  • 306
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16 (INK4a)
    • Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy JM. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16 (INK4a). Mol Cell 2004;14:501-513.
    • (2004) Mol Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.M.5
  • 308
    • 84904607485 scopus 로고    scopus 로고
    • P16INK4a, NAD, and sestrins: New targets for combating agingrelated chronic illness?
    • Pareja-Galeano H, Sanchis-Gomar F, Lucia A. p16INK4a, NAD, and sestrins: New targets for combating agingrelated chronic illness? J Cell Physiol 2014;229:1575-1576.
    • (2014) J Cell Physiol , vol.229 , pp. 1575-1576
    • Pareja-Galeano, H.1    Sanchis-Gomar, F.2    Lucia, A.3
  • 311
    • 84904990966 scopus 로고    scopus 로고
    • Inside and out: The activities of senescence in cancer
    • Perez-Mancera PA, Young AR, Narita M. Inside and out: The activities of senescence in cancer. Nat Rev Cancer 2014;14:547-558.
    • (2014) Nat Rev Cancer , vol.14 , pp. 547-558
    • Perez-Mancera, P.A.1    Young, A.R.2    Narita, M.3
  • 312
    • 77949881221 scopus 로고    scopus 로고
    • The senescenceassociated secretory phenotype: The dark side of tumor suppression
    • Coppe JP, Desprez PY, Krtolica A, Campisi J. The senescenceassociated secretory phenotype: The dark side of tumor suppression. Annu Rev Pathol 2010;5:99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppe, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 313
    • 84901288438 scopus 로고    scopus 로고
    • The role of senescent cells in ageing
    • Van Deursen JM. The role of senescent cells in ageing. Nature 2014;509:439-446.
    • (2014) Nature , vol.509 , pp. 439-446
    • Van Deursen, J.M.1
  • 314
    • 58849154235 scopus 로고    scopus 로고
    • Senescence-messaging secretome: SMS-ing cellular stress
    • Kuilman T, Peeper DS. Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer 2009;9:81-94.
    • (2009) Nat Rev Cancer , vol.9 , pp. 81-94
    • Kuilman, T.1    Peeper, D.S.2
  • 315
    • 84874603171 scopus 로고    scopus 로고
    • Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
    • Tchkonia T, Zhu Y, Van Deursen J, Campisi J, Kirkland JL. Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities. J Clin Invest 2013;123:966-972.
    • (2013) J Clin Invest , vol.123 , pp. 966-972
    • Tchkonia, T.1    Zhu, Y.2    Van Deursen, J.3    Campisi, J.4    Kirkland, J.L.5
  • 317
    • 84855836122 scopus 로고    scopus 로고
    • Physical exercise attenuates age-associated reduction in endotheliumreparative capacity of endothelial progenitor cells by increasing CXCR4/JAK-2 signaling in healthy men
    • Xia WH, Li J, Su C, Yang Z, Chen L, Wu F, Zhang YY, Yu BB, Qiu YX, Wang SM, Tao J. Physical exercise attenuates age-associated reduction in endotheliumreparative capacity of endothelial progenitor cells by increasing CXCR4/JAK-2 signaling in healthy men. Aging Cell 2012;11:111-119.
    • (2012) Aging Cell , vol.11 , pp. 111-119
    • Xia, W.H.1    Li, J.2    Su, C.3    Yang, Z.4    Chen, L.5    Wu, F.6    Zhang, Y.Y.7    Yu, B.B.8    Qiu, Y.X.9    Wang, S.M.10    Tao, J.11
  • 321
    • 47349116339 scopus 로고    scopus 로고
    • Stem cell review series: Aging of the skeletal muscle stem cell niche
    • Gopinath SD, Rando TA. Stem cell review series: Aging of the skeletal muscle stem cell niche. Aging Cell 2008;7:590-598.
    • (2008) Aging Cell , vol.7 , pp. 590-598
    • Gopinath, S.D.1    Rando, T.A.2
  • 323
    • 78149443609 scopus 로고    scopus 로고
    • Reduced satellite cell numbers and myogenic capacity in aging can be alleviated by endurance exercise
    • Shefer G, Rauner G, Yablonka-Reuveni Z, Benayahu D. Reduced satellite cell numbers and myogenic capacity in aging can be alleviated by endurance exercise. PLoS One 2010;5:e13307.
    • (2010) PLoS One , vol.5 , pp. e13307
    • Shefer, G.1    Rauner, G.2    Yablonka-Reuveni, Z.3    Benayahu, D.4
  • 324
    • 84882658142 scopus 로고    scopus 로고
    • Moderate-intensity treadmill running promotes expansion of the satellite cell pool in young and old mice
    • Shefer G, Rauner G, Stuelsatz P, Benayahu D, Yablonka-Reuveni Z. Moderate-intensity treadmill running promotes expansion of the satellite cell pool in young and old mice. FEBS J 2013;280:4063-4073.
    • (2013) FEBS J , vol.280 , pp. 4063-4073
    • Shefer, G.1    Rauner, G.2    Stuelsatz, P.3    Benayahu, D.4    Yablonka-Reuveni, Z.5
  • 326
    • 0034918907 scopus 로고    scopus 로고
    • Myogenic satellite cells: Physiology to molecular biology
    • Hawke TJ, Garry DJ. Myogenic satellite cells: Physiology to molecular biology. J Appl Physiol 2001;91:534-551.
    • (2001) J Appl Physiol , vol.91 , pp. 534-551
    • Hawke, T.J.1    Garry, D.J.2
  • 330
    • 64849110613 scopus 로고    scopus 로고
    • Skeletal muscle hypertrophy following resistance training is accompanied by a fiber type-specific increase in satellite cell content in elderly men
    • Verdijk LB, Gleeson BG, Jonkers RA, Meijer K, Savelberg HH, Dendale P, Van Loon LJ. Skeletal muscle hypertrophy following resistance training is accompanied by a fiber type-specific increase in satellite cell content in elderly men. J Gerontol A Biol Sci Med Sci 2009;64:332-339.
    • (2009) J Gerontol a Biol Sci Med Sci , vol.64 , pp. 332-339
    • Verdijk, L.B.1    Gleeson, B.G.2    Jonkers, R.A.3    Meijer, K.4    Savelberg, H.H.5    Dendale, P.6    Van Loon, L.J.7
  • 333
    • 84861771804 scopus 로고    scopus 로고
    • Myostatin is associated with age-related human muscle stem cell dysfunction
    • McKay BR, Ogborn DI, Bellamy LM, Tarnopolsky MA, Parise G. Myostatin is associated with age-related human muscle stem cell dysfunction. FASEB J 2012;26:2509-2521.
    • (2012) FASEB J , vol.26 , pp. 2509-2521
    • McKay, B.R.1    Ogborn, D.I.2    Bellamy, L.M.3    Tarnopolsky, M.A.4    Parise, G.5
  • 335
    • 84863329778 scopus 로고    scopus 로고
    • Inflammaging: Disturbed interplay between autophagy and inflammasomes
    • Salminen A, Kaarniranta K, Kauppinen A. Inflammaging: Disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) 2012;4:166-175.
    • (2012) Aging (Albany NY) , vol.4 , pp. 166-175
    • Salminen, A.1    Kaarniranta, K.2    Kauppinen, A.3
  • 336
    • 79959354999 scopus 로고    scopus 로고
    • Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
    • Green DR, Galluzzi L, Kroemer G. Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 2011;333:1109-1112.
    • (2011) Science , vol.333 , pp. 1109-1112
    • Green, D.R.1    Galluzzi, L.2    Kroemer, G.3
  • 338
    • 84863842721 scopus 로고    scopus 로고
    • MRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription
    • Pont AR, Sadri N, Hsiao SJ, Smith S, Schneider RJ. mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription. Mol Cell 2012;47:5-15.
    • (2012) Mol Cell , vol.47 , pp. 5-15
    • Pont, A.R.1    Sadri, N.2    Hsiao, S.J.3    Smith, S.4    Schneider, R.J.5
  • 339
    • 77953796856 scopus 로고    scopus 로고
    • Effect of chronic contractile activity on mRNA stability in skeletal muscle
    • Lai RY, Ljubicic V, D'Souza D, Hood DA. Effect of chronic contractile activity on mRNA stability in skeletal muscle. Am J Physiol Cell Physiol 2010;299:C155-C163.
    • (2010) Am J Physiol Cell Physiol , vol.299 , pp. C155-C163
    • Lai, R.Y.1    Ljubicic, V.2    D'Souza, D.3    Hood, D.A.4
  • 341
    • 84857638454 scopus 로고    scopus 로고
    • Muscular interleukin-6 and its role as an energy sensor
    • Pedersen BK. Muscular interleukin-6 and its role as an energy sensor. Med Sci Sports Exerc 2012;44:392-396.
    • (2012) Med Sci Sports Exerc , vol.44 , pp. 392-396
    • Pedersen, B.K.1
  • 342
    • 0034537933 scopus 로고    scopus 로고
    • Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise
    • Ostrowski K, Schjerling P, Pedersen BK. Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise. Eur J Appl Physiol 2000;83:512-515.
    • (2000) Eur J Appl Physiol , vol.83 , pp. 512-515
    • Ostrowski, K.1    Schjerling, P.2    Pedersen, B.K.3
  • 343
    • 33947529793 scopus 로고    scopus 로고
    • Interleukin-6 in acute exercise and training: What is the biological relevance?
    • Fischer CP. Interleukin-6 in acute exercise and training: What is the biological relevance? Exerc Immunol Rev 2006;12:6-33.
    • (2006) Exerc Immunol Rev , vol.12 , pp. 6-33
    • Fischer, C.P.1
  • 344
    • 55949119252 scopus 로고    scopus 로고
    • Muscle as an endocrine organ: Focus on muscle-derived interleukin-6
    • Pedersen BK, Febbraio MA. Muscle as an endocrine organ: Focus on muscle-derived interleukin-6. Physiol Rev 2008;88:1379-1406.
    • (2008) Physiol Rev , vol.88 , pp. 1379-1406
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 345
    • 84891309567 scopus 로고    scopus 로고
    • Muscle as a secretory organ
    • Pedersen BK. Muscle as a secretory organ. Compr Physiol 2013;3:1337-1362.
    • (2013) Compr Physiol , vol.3 , pp. 1337-1362
    • Pedersen, B.K.1
  • 348
    • 70349663748 scopus 로고    scopus 로고
    • Exercise training as a treatment for chronic inflammation in the elderly
    • Nicklas BJ, Brinkley TE. Exercise training as a treatment for chronic inflammation in the elderly. Exerc Sport Sci Rev 2009;37:165-170.
    • (2009) Exerc Sport Sci Rev , vol.37 , pp. 165-170
    • Nicklas, B.J.1    Brinkley, T.E.2
  • 349
    • 77954192215 scopus 로고    scopus 로고
    • Effect of exercise training on chronic inflammation
    • Beavers KM, Brinkley TE, Nicklas BJ. Effect of exercise training on chronic inflammation. Clin Chim Acta 2010;411:785-793.
    • (2010) Clin Chim Acta , vol.411 , pp. 785-793
    • Beavers, K.M.1    Brinkley, T.E.2    Nicklas, B.J.3
  • 354
    • 84864049574 scopus 로고    scopus 로고
    • Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy
    • Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT. Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy. Lancet 2012;380:219-229.
    • (2012) Lancet , vol.380 , pp. 219-229
    • Lee, I.M.1    Shiroma, E.J.2    Lobelo, F.3    Puska, P.4    Blair, S.N.5    Katzmarzyk, P.T.6
  • 355
    • 79955131355 scopus 로고    scopus 로고
    • Why physiology matters in medicine
    • Joyner MJ. Why physiology matters in medicine. Physiology (Bethesda) 2011;26:72-75.
    • (2011) Physiology (Bethesda) , vol.26 , pp. 72-75
    • Joyner, M.J.1
  • 356
    • 4043149218 scopus 로고    scopus 로고
    • Effects of extended outpatient rehabilitation after hip fracture: A randomized controlled trial
    • Binder EF, Brown M, Sinacore DR, Steger-May K, Yarasheski KE, Schechtman KB. Effects of extended outpatient rehabilitation after hip fracture: A randomized controlled trial. JAMA 2004;292:837-846.
    • (2004) JAMA , vol.292 , pp. 837-846
    • Binder, E.F.1    Brown, M.2    Sinacore, D.R.3    Steger-May, K.4    Yarasheski, K.E.5    Schechtman, K.B.6
  • 357
    • 1242306999 scopus 로고    scopus 로고
    • Muscle strength after resistance training is inversely correlated with baseline levels of soluble tumor necrosis factor receptors in the oldest old
    • Bruunsgaard H, Bjerregaard E, Schroll M, Pedersen BK. Muscle strength after resistance training is inversely correlated with baseline levels of soluble tumor necrosis factor receptors in the oldest old. J Am Geriatr Soc 2004;52:237-241.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 237-241
    • Bruunsgaard, H.1    Bjerregaard, E.2    Schroll, M.3    Pedersen, B.K.4
  • 358
    • 84898843190 scopus 로고    scopus 로고
    • Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians
    • Cadore EL, Casas-Herrero A, Zambom-Ferraresi F, Idoate F, Millor N, Gomez M, Rodriguez-Manas L, Izquierdo M. Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians. Age 2014;36:773-785.
    • (2014) Age , vol.36 , pp. 773-785
    • Cadore, E.L.1    Casas-Herrero, A.2    Zambom-Ferraresi, F.3    Idoate, F.4    Millor, N.5    Gomez, M.6    Rodriguez-Manas, L.7    Izquierdo, M.8
  • 359
    • 84865249725 scopus 로고    scopus 로고
    • Integration of balance and strength training into daily life activity to reduce rate of falls in older people (the LiFE study): Randomised parallel trial
    • Clemson L, Fiatarone Singh MA, Bundy A, Cumming RG, Manollaras K, O'Loughlin P, Black D. Integration of balance and strength training into daily life activity to reduce rate of falls in older people (the LiFE study): Randomised parallel trial. BMJ 2012;345:e4547.
    • (2012) BMJ , vol.345 , pp. e4547
    • Clemson, L.1    Fiatarone Singh, M.A.2    Bundy, A.3    Cumming, R.G.4    Manollaras, K.5    O'Loughlin, P.6    Black, D.7
  • 360
    • 37349116969 scopus 로고    scopus 로고
    • The effect of structured strength and balance training on cognitive function in frail, cognitive impaired elderly long-term care residents
    • Dorner T, Kranz A, Zettl-Wiedner K, Ludwig C, Rieder A, Gisinger C. The effect of structured strength and balance training on cognitive function in frail, cognitive impaired elderly long-term care residents. Aging Clin Exp Res 2007;19:400-405.
    • (2007) Aging Clin Exp Res , vol.19 , pp. 400-405
    • Dorner, T.1    Kranz, A.2    Zettl-Wiedner, K.3    Ludwig, C.4    Rieder, A.5    Gisinger, C.6
  • 362
    • 77956387777 scopus 로고    scopus 로고
    • Effects of traditional physical training and visual computer feedback training in frail elderly patients. A randomized intervention study
    • Hagedorn DK, Holm E. Effects of traditional physical training and visual computer feedback training in frail elderly patients. A randomized intervention study. Eur J Phys Rehab Medi 2010;46:159-168.
    • (2010) Eur J Phys Rehab Medi , vol.46 , pp. 159-168
    • Hagedorn, D.K.1    Holm, E.2
  • 363
    • 0035123736 scopus 로고    scopus 로고
    • Exercise training for rehabilitation and secondary prevention of falls in geriatric patients with a history of injurious falls
    • Hauer K, Rost B, Rutschle K, Opitz H, Specht N, Bartsch P, Oster P, Schlierf G. Exercise training for rehabilitation and secondary prevention of falls in geriatric patients with a history of injurious falls. J Am Geriatr Soc 2001;49:10-20.
    • (2001) J Am Geriatr Soc , vol.49 , pp. 10-20
    • Hauer, K.1    Rost, B.2    Rutschle, K.3    Opitz, H.4    Specht, N.5    Bartsch, P.6    Oster, P.7    Schlierf, G.8
  • 364
    • 84855828622 scopus 로고    scopus 로고
    • Physical training improves motor performance in people with dementia: A randomized controlled trial
    • Hauer K, Schwenk M, Zieschang T, Essig M, Becker C, Oster P. Physical training improves motor performance in people with dementia: A randomized controlled trial. J Am Geriatr Soc 2012;60:8-15.
    • (2012) J Am Geriatr Soc , vol.60 , pp. 8-15
    • Hauer, K.1    Schwenk, M.2    Zieschang, T.3    Essig, M.4    Becker, C.5    Oster, P.6
  • 365
    • 34547158136 scopus 로고    scopus 로고
    • Resistance training in the oldest old: Consequences for muscle strength, fiber types, fiber size, and MHC isoforms
    • Kryger AI, Andersen JL. Resistance training in the oldest old: Consequences for muscle strength, fiber types, fiber size, and MHC isoforms. Scand J Med Sci Sports 2007;17:422-430.
    • (2007) Scand J Med Sci Sports , vol.17 , pp. 422-430
    • Kryger, A.I.1    Andersen, J.L.2
  • 367
    • 0030070019 scopus 로고    scopus 로고
    • A walking program for nursing home residents: Effects on walk endurance, physical activity, mobility, and quality of life
    • MacRae PG, Asplund LA, Schnelle JF, Ouslander JG, Abrahamse A, Morris C. A walking program for nursing home residents: Effects on walk endurance, physical activity, mobility, and quality of life. J Am Geriatr Soc 1996;44:175-180.
    • (1996) J Am Geriatr Soc , vol.44 , pp. 175-180
    • MacRae, P.G.1    Asplund, L.A.2    Schnelle, J.F.3    Ouslander, J.G.4    Abrahamse, A.5    Morris, C.6
  • 368
    • 0028359203 scopus 로고
    • Improvements in quadriceps strength with regular seated exercise in the institutionalized elderly
    • McMurdo ME, Rennie LM. Improvements in quadriceps strength with regular seated exercise in the institutionalized elderly. Arch Phys Med Rehab 1994;75:600-603.
    • (1994) Arch Phys Med Rehab , vol.75 , pp. 600-603
    • McMurdo, M.E.1    Rennie, L.M.2
  • 369
    • 0029145353 scopus 로고
    • A randomized controlled trial of a home exercise programme for elderly people with poor mobility
    • McMurdo ME, Johnstone R. A randomized controlled trial of a home exercise programme for elderly people with poor mobility. Age Ageing 1995;24:425-428.
    • (1995) Age Ageing , vol.24 , pp. 425-428
    • McMurdo, M.E.1    Johnstone, R.2
  • 370
    • 84866354827 scopus 로고    scopus 로고
    • Whole-body vibration in addition to strength and balance exercise for falls-related functional mobility of frail older adults: A single-blind randomized controlled trial
    • Pollock RD, Martin FC, Newham DJ. Whole-body vibration in addition to strength and balance exercise for falls-related functional mobility of frail older adults: A single-blind randomized controlled trial. Clin Rehab 2012;26:915-923.
    • (2012) Clin Rehab , vol.26 , pp. 915-923
    • Pollock, R.D.1    Martin, F.C.2    Newham, D.J.3
  • 371
    • 0036718641 scopus 로고    scopus 로고
    • Translating clinical research into practice: A randomized controlled trial of exercise and incontinence care with nursing home residents
    • Schnelle JF, Alessi CA, Simmons SF, Al-Samarrai NR, Beck JC, Ouslander JG. Translating clinical research into practice: A randomized controlled trial of exercise and incontinence care with nursing home residents. J Am Geriatr Soc 2002;50:1476-1483.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1476-1483
    • Schnelle, J.F.1    Alessi, C.A.2    Simmons, S.F.3    Al-Samarrai, N.R.4    Beck, J.C.5    Ouslander, J.G.6
  • 372
    • 33645633884 scopus 로고    scopus 로고
    • Effects of a group-based exercise program on functional abilities in frail older women after hospital discharge
    • Timonen L, Rantanen T, Makinen E, Timonen TE, Tormakangas T, Sulkava R. Effects of a group-based exercise program on functional abilities in frail older women after hospital discharge. Aging Clin Exp Res 2006;18:50-56.
    • (2006) Aging Clin Exp Res , vol.18 , pp. 50-56
    • Timonen, L.1    Rantanen, T.2    Makinen, E.3    Timonen, T.E.4    Tormakangas, T.5    Sulkava, R.6
  • 374
    • 78651274000 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
    • Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, Craft S. Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 2011;68:51-57.
    • (2011) Arch Neurol , vol.68 , pp. 51-57
    • Baker, L.D.1    Cross, D.J.2    Minoshima, S.3    Belongia, D.4    Watson, G.S.5    Craft, S.6
  • 379
    • 79952219344 scopus 로고    scopus 로고
    • Resistance exercise training-induced muscle hypertrophy was associated with reduction of inflammatory markers in elderly women
    • Ogawa K, Sanada K, Machida S, Okutsu M, Suzuki K. Resistance exercise training-induced muscle hypertrophy was associated with reduction of inflammatory markers in elderly women. Mediators Inflamm 2010;2010:171023.
    • (2010) Mediators Inflamm , vol.2010 , pp. 171023
    • Ogawa, K.1    Sanada, K.2    Machida, S.3    Okutsu, M.4    Suzuki, K.5
  • 380
    • 78649573291 scopus 로고    scopus 로고
    • The effect of combined exercise training on carotid artery structure and function and vascular endothelial growth factor VEGF in obese older women
    • Park J, Nakamura Y, Kwon Y, Park H, Kim E, Park S. The effect of combined exercise training on carotid artery structure and function and vascular endothelial growth factor VEGF in obese older women. Japanese J Phys Fitness Sports Med 2010;59:495-504.
    • (2010) Japanese J Phys Fitness Sports Med , vol.59 , pp. 495-504
    • Park, J.1    Nakamura, Y.2    Kwon, Y.3    Park, H.4    Kim, E.5    Park, S.6
  • 384
    • 84911123407 scopus 로고    scopus 로고
    • The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: A randomised controlled trial
    • Vaughan S, Wallis M, Polit D, Steele M, Shum D, Morris N. The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: A randomised controlled trial. Age Ageing 2014;43:623-629.
    • (2014) Age Ageing , vol.43 , pp. 623-629
    • Vaughan, S.1    Wallis, M.2    Polit, D.3    Steele, M.4    Shum, D.5    Morris, N.6
  • 386
    • 33845387564 scopus 로고    scopus 로고
    • Effect of training on the response of plasma vascular endothelial growth factor to exercise in patients with peripheral arterial disease
    • Wood RE, Sanderson BE, Askew CD, Walker PJ, Green S, Stewart IB. Effect of training on the response of plasma vascular endothelial growth factor to exercise in patients with peripheral arterial disease. Clin Sci (Lond) 2006;111:401-409.
    • (2006) Clin Sci (Lond) , vol.111 , pp. 401-409
    • Wood, R.E.1    Sanderson, B.E.2    Askew, C.D.3    Walker, P.J.4    Green, S.5    Stewart, I.B.6
  • 387
    • 0037726553 scopus 로고    scopus 로고
    • IL-4 acts as a myoblast recruitment factor during mammalian muscle growth
    • Horsley V, Jansen KM, Mills ST, Pavlath GK. IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell 2003;113:483-494.
    • (2003) Cell , vol.113 , pp. 483-494
    • Horsley, V.1    Jansen, K.M.2    Mills, S.T.3    Pavlath, G.K.4
  • 388
    • 33645229678 scopus 로고    scopus 로고
    • Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo
    • Lafreniere JF, Mills P, Bouchentouf M, Tremblay JP. Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo. Exp Cell Res 2006;312:1127-1141.
    • (2006) Exp Cell Res , vol.312 , pp. 1127-1141
    • Lafreniere, J.F.1    Mills, P.2    Bouchentouf, M.3    Tremblay, J.P.4
  • 389
    • 33947311987 scopus 로고    scopus 로고
    • IL-13 mediates the recruitment of reserve cells for fusion during IGF-1-induced hypertrophy of human myotubes
    • Jacquemin V, Butler-Browne GS, Furling D, Mouly V. IL-13 mediates the recruitment of reserve cells for fusion during IGF-1-induced hypertrophy of human myotubes. J Cell Sci 2007;120:670-681.
    • (2007) J Cell Sci , vol.120 , pp. 670-681
    • Jacquemin, V.1    Butler-Browne, G.S.2    Furling, D.3    Mouly, V.4
  • 390
    • 42549159606 scopus 로고    scopus 로고
    • Beneficial synergistic interactions of TNF-alpha and IL-6 in C2 skeletal myoblasts-potential cross-talk with IGF system
    • Al-Shanti N, Saini A, Faulkner SH, Stewart CE. Beneficial synergistic interactions of TNF-alpha and IL-6 in C2 skeletal myoblasts-potential cross-talk with IGF system. Growth Factors 2008;26:61-73.
    • (2008) Growth Factors , vol.26 , pp. 61-73
    • Al-Shanti, N.1    Saini, A.2    Faulkner, S.H.3    Stewart, C.E.4
  • 393
    • 37449022587 scopus 로고    scopus 로고
    • Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy
    • Serrano AL, Baeza-Raja B, Perdiguero E, Jardi M, Munoz-Canoves P. Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab 2008;7:33-44.
    • (2008) Cell Metab , vol.7 , pp. 33-44
    • Serrano, A.L.1    Baeza-Raja, B.2    Perdiguero, E.3    Jardi, M.4    Munoz-Canoves, P.5
  • 395
    • 84866140306 scopus 로고    scopus 로고
    • Interleukin-15, IL-15 receptoralpha, and obesity: Concordance of laboratory animal and human genetic studies
    • Quinn LS, Anderson BG. Interleukin-15, IL-15 receptoralpha, and obesity: Concordance of laboratory animal and human genetic studies. J Obes 2011;2011:456347.
    • (2011) J Obes , vol.2011 , pp. 456347
    • Quinn, L.S.1    Anderson, B.G.2
  • 397
    • 23044481429 scopus 로고    scopus 로고
    • Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: Evidence for a skeletal muscle-tofat signaling pathway
    • Quinn LS, Strait-Bodey L, Anderson BG, Argiles JM, Havel PJ. Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: Evidence for a skeletal muscle-tofat signaling pathway. Cell Biol Int 2005;29:449-457.
    • (2005) Cell Biol Int , vol.29 , pp. 449-457
    • Quinn, L.S.1    Strait-Bodey, L.2    Anderson, B.G.3    Argiles, J.M.4    Havel, P.J.5
  • 399
    • 0030593489 scopus 로고    scopus 로고
    • Leukaemia inhibitory factor treatment stimulates muscle regeneration in the mdx mouse
    • Kurek J, Bower J, Romanella M, Austin L. Leukaemia inhibitory factor treatment stimulates muscle regeneration in the mdx mouse. Neurosci Lett 1996;212:167-170.
    • (1996) Neurosci Lett , vol.212 , pp. 167-170
    • Kurek, J.1    Bower, J.2    Romanella, M.3    Austin, L.4
  • 400
    • 33745819635 scopus 로고    scopus 로고
    • Leukemia inhibitory factor restores the hypertrophic response to increased loading in the LIF (-/-) mouse
    • Spangenburg EE, Booth FW. Leukemia inhibitory factor restores the hypertrophic response to increased loading in the LIF (-/-) mouse. Cytokine 2006;34:125-130.
    • (2006) Cytokine , vol.34 , pp. 125-130
    • Spangenburg, E.E.1    Booth, F.W.2
  • 401
    • 0035037449 scopus 로고    scopus 로고
    • Leukemia inhibitory factor enhances regeneration in skeletal muscles after myoblast transplantation
    • White JD, Bower JJ, Kurek JB, Austin L. Leukemia inhibitory factor enhances regeneration in skeletal muscles after myoblast transplantation. Muscle Nerve 2001;24:695-697.
    • (2001) Muscle Nerve , vol.24 , pp. 695-697
    • White, J.D.1    Bower, J.J.2    Kurek, J.B.3    Austin, L.4
  • 404
    • 79960831814 scopus 로고    scopus 로고
    • Novel events in the molecular regulation of muscle mass in critically ill patients
    • Constantin D, McCullough J, Mahajan RP, Greenhaff PL. Novel events in the molecular regulation of muscle mass in critically ill patients. J Physiol 2011;589:3883-3895.
    • (2011) J Physiol , vol.589 , pp. 3883-3895
    • Constantin, D.1    McCullough, J.2    Mahajan, R.P.3    Greenhaff, P.L.4
  • 406
    • 0036200822 scopus 로고    scopus 로고
    • Suppression of body fat accumulation in myostatin-deficient mice
    • McPherron AC, Lee SJ. Suppression of body fat accumulation in myostatin-deficient mice. J Clin Invest 2002;109:595-601.
    • (2002) J Clin Invest , vol.109 , pp. 595-601
    • McPherron, A.C.1    Lee, S.J.2
  • 409
    • 79961014704 scopus 로고    scopus 로고
    • Visfatin inhibits apoptosis of pancreatic beta-cell line, MIN6, via the mitogen-activated protein kinase/phosphoinositide 3-kinase pathway
    • Cheng Q, Dong W, Qian L, Wu J, Peng Y. Visfatin inhibits apoptosis of pancreatic beta-cell line, MIN6, via the mitogen-activated protein kinase/phosphoinositide 3-kinase pathway. J Mol Endocrinol 2011;47:13-21.
    • (2011) J Mol Endocrinol , vol.47 , pp. 13-21
    • Cheng, Q.1    Dong, W.2    Qian, L.3    Wu, J.4    Peng, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.