Melatonin prevents adverse myocardial infarction remodeling via Notch1/Mfn2 pathway

Free Radical Biology and Medicine

Volumn 97, Issue , 2016, Pages 408-417

  Pei, Haifeng ^a,b   Du, Jin ^a   Song, Xiaofeng ^a   He, Lei ^a   Zhang, Yufei ^c   Li, Xiuchuan ^a   Qiu, Chenming ^a   Zhang, Yangyang ^d   Hou, Juanni ^a   Feng, Juan ^a   Gao, Erhe ^e   Li, De ^a   Yang, Yongjian ^a,b  

^a CHENGDU MILITARY GENERAL HOSPITAL   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Melatonin; Mfn2; Mitochondria; Myocardial infarction; Notch1; ROS

Indexed keywords

CASPASE 3; JAGGED1; LUZINDOLE; MELATONIN; MITOFUSIN 2; NOTCH1 RECEPTOR; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; CARDIOTONIC AGENT; GUANOSINE TRIPHOSPHATASE; JAG1 PROTEIN, MOUSE; MFN2 PROTEIN, MOUSE; NOTCH1 PROTEIN, MOUSE; PROTEIN JAGGED 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC MUSCLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUPPLEMENTATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; HEART VENTRICLE REMODELING; METABOLISM; PATHOLOGY; PRECLINICAL STUDY;

ANIMALS; CARDIOTONIC AGENTS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GTP PHOSPHOHYDROLASES; JAGGED-1 PROTEIN; MALE; MELATONIN; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; VENTRICULAR REMODELING;

EID: 84978496414     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.06.015     Document Type: Article

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