Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: In vivo and in vitro studies

Journal of Pineal Research

Volumn 59, Issue 4, 2015, Pages 420-433

  Yu, Liming ^a   Liang, Hongliang ^a   Lu, Zhihong ^a   Zhao, Guolong ^b   Zhai, Mengen ^a   Yang, Yang ^c   Yang, Jian ^a   Yi, Dinghua ^a   Chen, Wensheng ^a   Wang, Xiaowu ^a   Duan, Weixun ^a   Jin, Zhenxiao ^a   Yu, Shiqiang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

melatonin; melatonin receptor; myocardial ischemia reperfusion; Notch1 signaling; oxidative stress

Indexed keywords

LUZINDOLE; MALONALDEHYDE; MELATONIN; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN KINASE B; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR HES 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CASPASE 3; HES1 PROTEIN, RAT; HOMEODOMAIN PROTEIN; MELATONIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; MYOCARDIAL REPERFUSION INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CASPASE 3; CELL LINE; HOMEODOMAIN PROTEINS; MALE; MELATONIN; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, NOTCH1; RECEPTORS, MELATONIN; SIGNAL TRANSDUCTION;

EID: 84946482378     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12272     Document Type: Article

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