메뉴 건너뛰기




Volumn 205, Issue 13, 2008, Pages 3173-3185

Control of the adaptive response of the heart to stress via the Notchl receptor pathway

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH1 RECEPTOR; ALANINE; AZEPINE DERIVATIVE; DRUG DERIVATIVE; N2 ((2S) 2 (3,5 DIFLUOROPHENYL) 2 HYDROXYETHANOYL) N1 ((7S) 5 METHYL 6 OXO 6,7 DIHYDRO 5H DIBENZO(B,D)AZEPIN 7 YL) L ALANINAMIDE; N2-((2S)-2-(3,5-DIFLUOROPHENYL)-2-HYDROXYETHANOYL)-N1-((7S)-5-METHYL-6-OXO-6,7-DIHYDRO-5H-DIBENZO(B,D)AZEPIN-7-YL)-L-ALANINAMIDE; SECRETASE; UNCLASSIFIED DRUG;

EID: 59649083972     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20081427     Document Type: Article
Times cited : (122)

References (48)
  • 1
    • 0031789272 scopus 로고    scopus 로고
    • The global burden of disease, 1990-2020
    • Lopez, A.D., and C.C. Murray. 1998. The global burden of disease, 1990-2020. Nat. Med. 4:1241-1243.
    • (1998) Nat. Med , vol.4 , pp. 1241-1243
    • Lopez, A.D.1    Murray, C.C.2
  • 2
    • 0037050022 scopus 로고    scopus 로고
    • The failing heart
    • Towbin, J.A., and N.E. Bowles. 2002. The failing heart. Nature. 415:227-233.
    • (2002) Nature , vol.415 , pp. 227-233
    • Towbin, J.A.1    Bowles, N.E.2
  • 3
    • 0033520388 scopus 로고    scopus 로고
    • Stress pathways and heart failure
    • Chien, K.R. 1999. Stress pathways and heart failure. Cell. 98:555-558.
    • (1999) Cell , vol.98 , pp. 555-558
    • Chien, K.R.1
  • 7
    • 22144455675 scopus 로고    scopus 로고
    • FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes
    • Rosenblatt-Velin, N., M.G. Lepore, C. Cartoni, F. Beermann, and T. Pedrazzini. 2005. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J. Clin. Invest. 115:1724-1733.
    • (2005) J. Clin. Invest , vol.115 , pp. 1724-1733
    • Rosenblatt-Velin, N.1    Lepore, M.G.2    Cartoni, C.3    Beermann, F.4    Pedrazzini, T.5
  • 9
    • 1542317449 scopus 로고    scopus 로고
    • Notch regulation of lymphocyte development and function
    • Radtke, F., A. Wilson, S.J. Mancini, and H.R. Macdonald. 2004. Notch regulation of lymphocyte development and function. Nat. Immunol. 5:247-253.
    • (2004) Nat. Immunol , vol.5 , pp. 247-253
    • Radtke, F.1    Wilson, A.2    Mancini, S.J.3    Macdonald, H.R.4
  • 10
    • 33646551228 scopus 로고    scopus 로고
    • Multiple functions of Notch signaling in self-renewing organs and cancer
    • Wilson, A., and F. Radtke. 2006. Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett. 580:2860-2868.
    • (2006) FEBS Lett , vol.580 , pp. 2860-2868
    • Wilson, A.1    Radtke, F.2
  • 11
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray, S.J. 2006. Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7:678-689.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 12
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso, T., L. Kedes, and Y. Hamamori. 2003. HES and HERP families: multiple effectors of the Notch signaling pathway. J. Cell. Physiol. 194:237-255.
    • (2003) J. Cell. Physiol , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 13
    • 30444457864 scopus 로고    scopus 로고
    • Notch signaling in hematopoiesis and lymphopoiesis: Lessons from Drosophila
    • Radtke, F., A. Wilson, and H.R. Macdonald. 2005. Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila. Bioessays. 27:1117-1128.
    • (2005) Bioessays , vol.27 , pp. 1117-1128
    • Radtke, F.1    Wilson, A.2    Macdonald, H.R.3
  • 14
    • 34548164780 scopus 로고    scopus 로고
    • Notch signaling in vascular development and physiology
    • Gridley, T. 2007. Notch signaling in vascular development and physiology. Development. 134:2709-2718.
    • (2007) Development , vol.134 , pp. 2709-2718
    • Gridley, T.1
  • 15
    • 34047097013 scopus 로고    scopus 로고
    • Control of cardiogenesis by the notch pathway
    • Pedrazzini, T. 2007. Control of cardiogenesis by the notch pathway. Trends Cardiovasc. Med. 17:83-90.
    • (2007) Trends Cardiovasc. Med , vol.17 , pp. 83-90
    • Pedrazzini, T.1
  • 16
    • 37449010541 scopus 로고    scopus 로고
    • The multifaceted role of Notch in cardiac development and disease
    • High, F.A., and J.A. Epstein. 2008. The multifaceted role of Notch in cardiac development and disease. Nat. Rev. Genet. 9:49-61.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 49-61
    • High, F.A.1    Epstein, J.A.2
  • 18
    • 13244298117 scopus 로고    scopus 로고
    • Notch and epithelial-mesenchyme transition in development and tumor progression: Another turn of the screw
    • Grego-Bessa, J., J. Diez, L. Timmerman, and J.L. De La Pompa. 2004. Notch and epithelial-mesenchyme transition in development and tumor progression: another turn of the screw. Cell Cycle. 3:718-721.
    • (2004) Cell Cycle , vol.3 , pp. 718-721
    • Grego-Bessa, J.1    Diez, J.2    Timmerman, L.3    De La Pompa, J.L.4
  • 20
    • 0036808790 scopus 로고    scopus 로고
    • Characterization of Notch receptor expression in the developing mammalian heart and liver. Am. J. Med. Genet. 112:181-189.
    • Characterization of Notch receptor expression in the developing mammalian heart and liver. Am. J. Med. Genet. 112:181-189.
  • 24
    • 0031811360 scopus 로고    scopus 로고
    • Mazzolai, L., J . Nussberger, J .F. Aubert, D.B. Brunner, G. Gabbiani, H.R. Brunner, and T. Pedrazzini. 1998. Blood pressure-independentcardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension. 31:1324-1330.
    • Mazzolai, L., J . Nussberger, J .F. Aubert, D.B. Brunner, G. Gabbiani, H.R. Brunner, and T. Pedrazzini. 1998. Blood pressure-independentcardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension. 31:1324-1330.
  • 25
    • 23244440907 scopus 로고    scopus 로고
    • Angiotensin II-mediated phenotypic cardio-myocyte remodeling leads to age-dependent cardiac dysfunction and failure
    • Domenighetti, A.A., Q. Wang, M. Egger, S.M. Richards, T. Pedrazzini, and L.M. Delbridge. 2005. Angiotensin II-mediated phenotypic cardio-myocyte remodeling leads to age-dependent cardiac dysfunction and failure. Hypertension. 46:426-432.
    • (2005) Hypertension , vol.46 , pp. 426-432
    • Domenighetti, A.A.1    Wang, Q.2    Egger, M.3    Richards, S.M.4    Pedrazzini, T.5    Delbridge, L.M.6
  • 26
    • 33751160615 scopus 로고    scopus 로고
    • Studies to investigate the in vivo therapeutic window of the gamma-secretase inhibitor N2-[(2S)-2-(3,5- difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo -6,7-dihydro-5H- dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY411,575) in the CRND8 mouse
    • Hyde, L.A., N.A. McHugh, J. Chen, Q. Zhang, D. Manfra, A.A. Nomeir, H. Josien, T. Bara, J.W. Clader, L. Zhang, et al. 2006. Studies to investigate the in vivo therapeutic window of the gamma-secretase inhibitor N2-[(2S)-2-(3,5- difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo -6,7-dihydro-5H- dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY411,575) in the CRND8 mouse. J. Pharmacol. Exp. Ther. 319:1133-1143.
    • (2006) J. Pharmacol. Exp. Ther , vol.319 , pp. 1133-1143
    • Hyde, L.A.1    McHugh, N.A.2    Chen, J.3    Zhang, Q.4    Manfra, D.5    Nomeir, A.A.6    Josien, H.7    Bara, T.8    Clader, J.W.9    Zhang, L.10
  • 28
    • 0030940061 scopus 로고    scopus 로고
    • Two-kidney, one clip and one-kidney, one clip hypertension in mice
    • Wiesel, P., L. Mazzolai, J. Nussberger, and T. Pedrazzini. 1997. Two-kidney, one clip and one-kidney, one clip hypertension in mice. Hypertension. 29:1025-1030.
    • (1997) Hypertension , vol.29 , pp. 1025-1030
    • Wiesel, P.1    Mazzolai, L.2    Nussberger, J.3    Pedrazzini, T.4
  • 29
    • 0031799964 scopus 로고    scopus 로고
    • Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis
    • Chen, J ., S.W. Kubalak, and K.R. Chien. 1998. Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development. 125:1943-1949.
    • (1998) Development , vol.125 , pp. 1943-1949
    • Chen, J.1    Kubalak, S.W.2    Chien, K.R.3
  • 30
    • 0033136717 scopus 로고    scopus 로고
    • Radtke, F., A. Wilson, G. Stark, M. Bauer, J . van Meerwijk, H.R. Macdonald, and M. Aguet. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity. 10:547-558.
    • Radtke, F., A. Wilson, G. Stark, M. Bauer, J . van Meerwijk, H.R. Macdonald, and M. Aguet. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity. 10:547-558.
  • 32
    • 26444558081 scopus 로고    scopus 로고
    • Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts
    • Fischer, A., J. Klattig, B. Kneitz, H. Diez, M. Maier, B. Holtmann, C. Englert, and M. Gessler. 2005. Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol. Cell. Biol. 25:8960-8970.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 8960-8970
    • Fischer, A.1    Klattig, J.2    Kneitz, B.3    Diez, H.4    Maier, M.5    Holtmann, B.6    Englert, C.7    Gessler, M.8
  • 33
    • 34249932672 scopus 로고    scopus 로고
    • Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
    • Xin, M., E.M. Small, E. van Rooij, X. Qi, J.A. Richardson, D. Srivastava, O. Nakagawa, and E.N. Olson. 2007. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc. Natl. Acad. Sci. USA. 104:7975-7980.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7975-7980
    • Xin, M.1    Small, E.M.2    van Rooij, E.3    Qi, X.4    Richardson, J.A.5    Srivastava, D.6    Nakagawa, O.7    Olson, E.N.8
  • 34
    • 33646415903 scopus 로고    scopus 로고
    • Xiang, F., Y. Sakata, L. Cui, J .M. Youngblood, H. Nakagami, J .K. Liao, R. Liao, and M.T. Chin. 2006. Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4. Am. J. Physiol. Heart Circ. Physiol. 290:H1997-H2006.
    • Xiang, F., Y. Sakata, L. Cui, J .M. Youngblood, H. Nakagami, J .K. Liao, R. Liao, and M.T. Chin. 2006. Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4. Am. J. Physiol. Heart Circ. Physiol. 290:H1997-H2006.
  • 36
    • 34547863871 scopus 로고    scopus 로고
    • Cardiovascular regeneration in non-mammalian model systems: What are the differences between newts and man?
    • Borchardt, T., and T. Braun. 2007. Cardiovascular regeneration in non-mammalian model systems: what are the differences between newts and man? Thromb. Haemost. 98:311-318.
    • (2007) Thromb. Haemost , vol.98 , pp. 311-318
    • Borchardt, T.1    Braun, T.2
  • 37
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • Poss, K.D., L.G. Wilson, and M.T. Keating. 2002. Heart regeneration in zebrafish. Science. 298:2188-2190.
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 39
    • 33646182727 scopus 로고    scopus 로고
    • Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control
    • Crosnier, C., D. Stamataki, and J. Lewis. 2006. Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nat. Rev. Genet. 7:349-359.
    • (2006) Nat. Rev. Genet , vol.7 , pp. 349-359
    • Crosnier, C.1    Stamataki, D.2    Lewis, J.3
  • 40
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy, I.M., M.J. Conboy, G.M. Smythe, and T.A. Rando. 2003. Notch-mediated restoration of regenerative potential to aged muscle. Science. 302:1575-1577.
    • (2003) Science , vol.302 , pp. 1575-1577
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 41
    • 4344717801 scopus 로고    scopus 로고
    • Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes
    • Ahuja, P., E. Perriard, J .C. Perriard, and E. Ehler. 2004. Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes. J. Cell Sci. 117:3295-3306.
    • (2004) J. Cell Sci , vol.117 , pp. 3295-3306
    • Ahuja, P.1    Perriard, E.2    Perriard, J.C.3    Ehler, E.4
  • 43
    • 33746517512 scopus 로고    scopus 로고
    • Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling
    • Nemir, M., A. Croquelois, T. Pedrazzini, and F. Radtke. 2006. Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circ. Res. 98:1471-1478.
    • (2006) Circ. Res , vol.98 , pp. 1471-1478
    • Nemir, M.1    Croquelois, A.2    Pedrazzini, T.3    Radtke, F.4
  • 46
    • 0036744815 scopus 로고    scopus 로고
    • The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
    • Conboy, I.M., and T.A. Rando. 2002. The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev. Cell. 3:397-409.
    • (2002) Dev. Cell , vol.3 , pp. 397-409
    • Conboy, I.M.1    Rando, T.A.2
  • 47
    • 33745762804 scopus 로고    scopus 로고
    • Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
    • Shinin, V., B. Gayraud-Morel, D. Gomes, and S. Tajbakhsh. 2006. Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat. Cell Biol. 8:677-687.
    • (2006) Nat. Cell Biol , vol.8 , pp. 677-687
    • Shinin, V.1    Gayraud-Morel, B.2    Gomes, D.3    Tajbakhsh, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.