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Volumn 119, Issue 4, 2016, Pages 244-253

GATA transcription factor as a likely key regulator of the Caenorhabditis elegans innate immune response against gut pathogens

Author keywords

Caenorhabditis elegans; GATA transcription factor; Innate immunity; RNA Seq; WormExp

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; TRANSCRIPTION FACTOR GATA;

EID: 84977650927     PISSN: 09442006     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.zool.2016.05.013     Document Type: Article
Times cited : (25)

References (80)
  • 1
    • 84901740617 scopus 로고    scopus 로고
    • A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology
    • Andersen, E.C., Bloom, J.S., Gerke, J.P., Kruglyak, L., A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology. PLoS Genet., 10, 2014, e1004156.
    • (2014) PLoS Genet. , vol.10 , pp. e1004156
    • Andersen, E.C.1    Bloom, J.S.2    Gerke, J.P.3    Kruglyak, L.4
  • 4
    • 84989777778 scopus 로고    scopus 로고
    • GATA transcription factors as tissue-specific master regulators for induced responses
    • Block, D.H., Shapira, M., GATA transcription factors as tissue-specific master regulators for induced responses. Worm, 4, 2015, e1118607.
    • (2015) Worm , vol.4 , pp. e1118607
    • Block, D.H.1    Shapira, M.2
  • 5
    • 84930815231 scopus 로고    scopus 로고
    • The developmental intestinal regulator ELT-2 controls p38-dependent immune responses in adult C. elegans
    • Block, D.H., Twumasi-Boateng, K., Kang, H.S., Carlisle, J.A., Hanganu, A., Lai, T.Y.-J., Shapira, M., The developmental intestinal regulator ELT-2 controls p38-dependent immune responses in adult C. elegans. PLoS Genet., 11, 2015, e1005265.
    • (2015) PLoS Genet. , vol.11 , pp. e1005265
    • Block, D.H.1    Twumasi-Boateng, K.2    Kang, H.S.3    Carlisle, J.A.4    Hanganu, A.5    Lai, T.Y.-J.6    Shapira, M.7
  • 6
    • 80052538735 scopus 로고    scopus 로고
    • Protist-type lysozymes of the nematode Caenorhabditis elegans contribute to resistance against pathogenic Bacillus thuringiensis
    • Boehnisch, C., Wong, D., Habig, M., Isermann, K., Michiels, N.K., Roeder, T., May, R.C., Schulenburg, H., Protist-type lysozymes of the nematode Caenorhabditis elegans contribute to resistance against pathogenic Bacillus thuringiensis. PLoS One, 6, 2011, e24619.
    • (2011) PLoS One , vol.6 , pp. e24619
    • Boehnisch, C.1    Wong, D.2    Habig, M.3    Isermann, K.4    Michiels, N.K.5    Roeder, T.6    May, R.C.7    Schulenburg, H.8
  • 7
    • 84956657857 scopus 로고    scopus 로고
    • Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity
    • Bond, M.R., Ghosh, S.K., Wang, P., Hanover, J.A., Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity. PLoS One, 9, 2014, e113231.
    • (2014) PLoS One , vol.9 , pp. e113231
    • Bond, M.R.1    Ghosh, S.K.2    Wang, P.3    Hanover, J.A.4
  • 8
    • 84922481687 scopus 로고    scopus 로고
    • Immunity in Drosophila melanogaster – from microbial recognition to whole-organism physiology
    • Buchon, N., Silverman, N., Cherry, S., Immunity in Drosophila melanogaster – from microbial recognition to whole-organism physiology. Nature Rev. Immunol 14 (2014), 796–810.
    • (2014) Nature Rev. Immunol , vol.14 , pp. 796-810
    • Buchon, N.1    Silverman, N.2    Cherry, S.3
  • 9
    • 70350439116 scopus 로고    scopus 로고
    • Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans
    • Chávez, V., Mohri-Shiomi, A., Garsin, D.A., Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans. Infect. Immun 77 (2009), 4983–4989.
    • (2009) Infect. Immun , vol.77 , pp. 4983-4989
    • Chávez, V.1    Mohri-Shiomi, A.2    Garsin, D.A.3
  • 10
    • 34547685783 scopus 로고    scopus 로고
    • Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver – a role for growth hormone in alternative exon usage
    • Cheung, L., Andersen, M., Gustavsson, C., Odeberg, J., Fernández-Pérez, L., Norstedt, G., Tollet-Egnell, P., Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver – a role for growth hormone in alternative exon usage. BMC Mol. Biol., 8, 2007, 60.
    • (2007) BMC Mol. Biol. , vol.8 , pp. 60
    • Cheung, L.1    Andersen, M.2    Gustavsson, C.3    Odeberg, J.4    Fernández-Pérez, L.5    Norstedt, G.6    Tollet-Egnell, P.7
  • 11
    • 84890250693 scopus 로고    scopus 로고
    • Commensals: probiotics and pathogens in the Caenorhabditis elegans model
    • Clark, L.C., Hodgkin, J., Commensals: probiotics and pathogens in the Caenorhabditis elegans model. Cell. Microbiol. 16 (2014), 27–38.
    • (2014) Cell. Microbiol. , vol.16 , pp. 27-38
    • Clark, L.C.1    Hodgkin, J.2
  • 12
    • 84912100014 scopus 로고    scopus 로고
    • Microbial pathogenesis and host defense in the nematode C. elegans
    • Cohen, L.B., Troemel, E.R., Microbial pathogenesis and host defense in the nematode C. elegans. Curr. Opin. Microbiol. 23 (2015), 94–101.
    • (2015) Curr. Opin. Microbiol. , vol.23 , pp. 94-101
    • Cohen, L.B.1    Troemel, E.R.2
  • 13
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault, C., Pujol, N., Reboul, J., Sabatier, L., Guichou, J.-F., Kohara, Y., Ewbank, J.J., TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nature Immunol. 5 (2004), 488–494.
    • (2004) Nature Immunol. , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.-F.5    Kohara, Y.6    Ewbank, J.J.7
  • 15
    • 79956075019 scopus 로고    scopus 로고
    • Unusual regulation of a STAT protein by an SLC6 family transporter in C. elegans epidermal innate immunity
    • Dierking, K., Polanowska, J., Omi, S., Engelmann, I., Gut, M., Lembo, F., Ewbank, J.J., Pujol, N., Unusual regulation of a STAT protein by an SLC6 family transporter in C. elegans epidermal innate immunity. Cell Host Microbe 9 (2011), 425–435.
    • (2011) Cell Host Microbe , vol.9 , pp. 425-435
    • Dierking, K.1    Polanowska, J.2    Omi, S.3    Engelmann, I.4    Gut, M.5    Lembo, F.6    Ewbank, J.J.7    Pujol, N.8
  • 16
    • 84966293235 scopus 로고    scopus 로고
    • Antimicrobial effectors in the nematode C. elegans – an outgroup to the Arthropoda
    • Dierking, K., Yang, W., Schulenburg, H., Antimicrobial effectors in the nematode C. elegans – an outgroup to the Arthropoda. Phil. Trans. R. Soc. B, 371, 2016, 20150299.
    • (2016) Phil. Trans. R. Soc. B , vol.371 , pp. 20150299
    • Dierking, K.1    Yang, W.2    Schulenburg, H.3
  • 17
    • 84934439394 scopus 로고    scopus 로고
    • Innate immunity in C. elegans
    • K. Söderhäll Springer New York
    • Engelmann, I., Pujol, N., Innate immunity in C. elegans. Söderhäll, K., (eds.) Invertebrate Immunity, 2010, Springer, New York, 105–121.
    • (2010) Invertebrate Immunity , pp. 105-121
    • Engelmann, I.1    Pujol, N.2
  • 18
    • 76649117141 scopus 로고    scopus 로고
    • bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans
    • Estes, K.A., Dunbar, T.L., Powell, J.R., Ausubel, F.M., Troemel, E.R., bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 2153–2158.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 2153-2158
    • Estes, K.A.1    Dunbar, T.L.2    Powell, J.R.3    Ausubel, F.M.4    Troemel, E.R.5
  • 19
    • 84946036909 scopus 로고    scopus 로고
    • Local and long-range activation of innate immunity by infection and damage in C. elegans
    • Ewbank, J.J., Pujol, N., Local and long-range activation of innate immunity by infection and damage in C. elegans. Curr. Opin. Immunol. 38 (2016), 1–7.
    • (2016) Curr. Opin. Immunol. , vol.38 , pp. 1-7
    • Ewbank, J.J.1    Pujol, N.2
  • 20
    • 0032526161 scopus 로고    scopus 로고
    • The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
    • Fukushige, T., Hawkins, M.G., McGhee, J.D., The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev. Biol. 198 (1998), 286–302.
    • (1998) Dev. Biol. , vol.198 , pp. 286-302
    • Fukushige, T.1    Hawkins, M.G.2    McGhee, J.D.3
  • 21
    • 84869502241 scopus 로고    scopus 로고
    • ChIP-seq and beyond: new and improved methodologies to detect and characterize protein–DNA interactions
    • Furey, T.S., ChIP-seq and beyond: new and improved methodologies to detect and characterize protein–DNA interactions. Nature Rev. Genet. 13 (2012), 840–852.
    • (2012) Nature Rev. Genet. , vol.13 , pp. 840-852
    • Furey, T.S.1
  • 22
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation
    • Garigan, D., Hsu, A.-L., Fraser, A.G., Kamath, R.S., Ahringer, J., Kenyon, C., Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161 (2002), 1101–1112.
    • (2002) Genetics , vol.161 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.-L.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Kenyon, C.6
  • 24
    • 0034036321 scopus 로고    scopus 로고
    • Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    • Gems, D., Riddle, D.L., Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. Genetics 154 (2000), 1597–1610.
    • (2000) Genetics , vol.154 , pp. 1597-1610
    • Gems, D.1    Riddle, D.L.2
  • 28
    • 0023764283 scopus 로고
    • Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
    • Hughes, A.L., Nei, M., Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection. Nature 335 (1988), 167–170.
    • (1988) Nature , vol.335 , pp. 167-170
    • Hughes, A.L.1    Nei, M.2
  • 30
    • 72949096858 scopus 로고    scopus 로고
    • Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates
    • Irazoqui, J.E., Urbach, J.M., Ausubel, F.M., Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nature Rev. Immunol. 10 (2010), 47–58.
    • (2010) Nature Rev. Immunol. , vol.10 , pp. 47-58
    • Irazoqui, J.E.1    Urbach, J.M.2    Ausubel, F.M.3
  • 31
    • 0003732734 scopus 로고    scopus 로고
    • Immunobiology: The Immune System in Health and Disease
    • Churchill Livingstone London
    • Janeway, C.A., Travers, P., Walport, M., Shlomchik, M.J., Immunobiology: The Immune System in Health and Disease. 2001, Churchill Livingstone, London.
    • (2001)
    • Janeway, C.A.1    Travers, P.2    Walport, M.3    Shlomchik, M.J.4
  • 33
    • 84959863448 scopus 로고    scopus 로고
    • Graded proteasome dysfunction in Caenorhabditis elegans activates an adaptive response involving the conserved SKN-1 and ELT-2 transcription factors and the autophagy-lysosome pathway
    • Keith, S.A., Maddux, S.K., Zhong, Y., Chinchankar, M.N., Ferguson, A.A., Ghazi, A., Fisher, A.L., Graded proteasome dysfunction in Caenorhabditis elegans activates an adaptive response involving the conserved SKN-1 and ELT-2 transcription factors and the autophagy-lysosome pathway. PLoS Genet., 12, 2016, e1005823.
    • (2016) PLoS Genet. , vol.12 , pp. e1005823
    • Keith, S.A.1    Maddux, S.K.2    Zhong, Y.3    Chinchankar, M.N.4    Ferguson, A.A.5    Ghazi, A.6    Fisher, A.L.7
  • 34
    • 54949117914 scopus 로고    scopus 로고
    • GATA transcription factor required for immunity to bacterial and fungal pathogens
    • Kerry, S., TeKippe, M., Gaddis, N.C., Aballay, A., GATA transcription factor required for immunity to bacterial and fungal pathogens. PLoS One, 1, 2006, e77.
    • (2006) PLoS One , vol.1 , pp. e77
    • Kerry, S.1    TeKippe, M.2    Gaddis, N.C.3    Aballay, A.4
  • 36
    • 84861129960 scopus 로고    scopus 로고
    • Caenorhabditis elegans: a model organism for investigating immunity
    • Marsh, E.K., May, R.C., Caenorhabditis elegans: a model organism for investigating immunity. Appl. Environm. Microbiol. 78 (2012), 2075–2081.
    • (2012) Appl. Environm. Microbiol. , vol.78 , pp. 2075-2081
    • Marsh, E.K.1    May, R.C.2
  • 37
  • 40
    • 84859765702 scopus 로고    scopus 로고
    • Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses
    • Melo, J.A., Ruvkun, G., Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell 149 (2012), 452–466.
    • (2012) Cell , vol.149 , pp. 452-466
    • Melo, J.A.1    Ruvkun, G.2
  • 41
    • 33748255705 scopus 로고    scopus 로고
    • Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences
    • Michaloski, J.S., Galante, P.A., Malnic, B., Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Genome Res. 16 (2006), 1091–1098.
    • (2006) Genome Res. , vol.16 , pp. 1091-1098
    • Michaloski, J.S.1    Galante, P.A.2    Malnic, B.3
  • 45
    • 33746727711 scopus 로고    scopus 로고
    • Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum
    • O'Rourke, D., Baban, D., Demidova, M., Mott, R., Hodgkin, J., Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. Genome Res. 16 (2006), 1005–1016.
    • (2006) Genome Res. , vol.16 , pp. 1005-1016
    • O'Rourke, D.1    Baban, D.2    Demidova, M.3    Mott, R.4    Hodgkin, J.5
  • 46
    • 84861215311 scopus 로고    scopus 로고
    • A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans
    • Papp, D., Csermely, P., Soti, C., A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans. PLoS Pathog., 8, 2012, e1002673.
    • (2012) PLoS Pathog. , vol.8 , pp. e1002673
    • Papp, D.1    Csermely, P.2    Soti, C.3
  • 47
    • 84921774753 scopus 로고    scopus 로고
    • Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
    • Pellegrino, M.W., Nargund, A.M., Kirienko, N.V., Gillis, R., Fiorese, C.J., Haynes, C.M., Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection. Nature 516 (2014), 414–417.
    • (2014) Nature , vol.516 , pp. 414-417
    • Pellegrino, M.W.1    Nargund, A.M.2    Kirienko, N.V.3    Gillis, R.4    Fiorese, C.J.5    Haynes, C.M.6
  • 48
    • 84923556425 scopus 로고    scopus 로고
    • Why we need more ecology for genetic models such as C. elegans
    • Petersen, C., Dirksen, P., Schulenburg, H., Why we need more ecology for genetic models such as C. elegans. Trends Genet. 31 (2015), 120–127.
    • (2015) Trends Genet. , vol.31 , pp. 120-127
    • Petersen, C.1    Dirksen, P.2    Schulenburg, H.3
  • 49
    • 45549095755 scopus 로고    scopus 로고
    • Models of Caenorhabditis elegans infection by bacterial and fungal pathogens
    • Powell, J.R., Ausubel, F.M., Models of Caenorhabditis elegans infection by bacterial and fungal pathogens. Methods Mol. Biol. 415 (2008), 403–427.
    • (2008) Methods Mol. Biol. , vol.415 , pp. 403-427
    • Powell, J.R.1    Ausubel, F.M.2
  • 51
    • 84857064084 scopus 로고    scopus 로고
    • Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium
    • Pukkila-Worley, R., Ausubel, F.M., Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium. Curr. Opin. Immunol. 24 (2012), 3–9.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 3-9
    • Pukkila-Worley, R.1    Ausubel, F.M.2
  • 52
    • 64049100454 scopus 로고    scopus 로고
    • Protein kinase D is an essential regulator of C. elegans innate immunity
    • Ren, M., Feng, H., Fu, Y., Land, M., Rubin, C.S., Protein kinase D is an essential regulator of C. elegans innate immunity. Immunity 30 (2009), 521–532.
    • (2009) Immunity , vol.30 , pp. 521-532
    • Ren, M.1    Feng, H.2    Fu, Y.3    Land, M.4    Rubin, C.S.5
  • 53
    • 77953051715 scopus 로고    scopus 로고
    • Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans
    • Roberts, A.F., Gumienny, T.L., Gleason, R.J., Wang, H., Padgett, R.W., Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans. BMC Dev. Biol., 10, 2010, 61.
    • (2010) BMC Dev. Biol. , vol.10 , pp. 61
    • Roberts, A.F.1    Gumienny, T.L.2    Gleason, R.J.3    Wang, H.4    Padgett, R.W.5
  • 54
    • 70450222505 scopus 로고    scopus 로고
    • Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity
    • Roeder, T., Stanisak, M., Gelhaus, C., Bruchhaus, I., Grötzinger, J., Leippe, M., Caenopores are antimicrobial peptides in the nematode Caenorhabditis elegans instrumental in nutrition and immunity. Dev. Comp. Immunol. 34 (2010), 203–209.
    • (2010) Dev. Comp. Immunol. , vol.34 , pp. 203-209
    • Roeder, T.1    Stanisak, M.2    Gelhaus, C.3    Bruchhaus, I.4    Grötzinger, J.5    Leippe, M.6
  • 55
    • 84945180435 scopus 로고    scopus 로고
    • A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
    • Roh, H.C., Dimitrov, I., Deshmukh, K., Zhao, G., Warnhoff, K., Cabrera, D., Tsai, W., Kornfeld, K., A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. Nucleic Acids Res. 43 (2015), 803–816.
    • (2015) Nucleic Acids Res. , vol.43 , pp. 803-816
    • Roh, H.C.1    Dimitrov, I.2    Deshmukh, K.3    Zhao, G.4    Warnhoff, K.5    Cabrera, D.6    Tsai, W.7    Kornfeld, K.8
  • 56
    • 77749305020 scopus 로고    scopus 로고
    • Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans
    • Rohlfing, A.-K., Miteva, Y., Hannenhalli, S., Lamitina, T., Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans. PLoS One, 5, 2010, e9010.
    • (2010) PLoS One , vol.5 , pp. e9010
    • Rohlfing, A.-K.1    Miteva, Y.2    Hannenhalli, S.3    Lamitina, T.4
  • 58
    • 84907993113 scopus 로고    scopus 로고
    • TOR signaling couples oxygen sensing to lifespan in C. elegans
    • Schieber, M., Chandel, N.S., TOR signaling couples oxygen sensing to lifespan in C. elegans. Cell Rep. 9 (2014), 9–15.
    • (2014) Cell Rep. , vol.9 , pp. 9-15
    • Schieber, M.1    Chandel, N.S.2
  • 59
    • 43549106617 scopus 로고    scopus 로고
    • Diversification and adaptive sequence evolution of Caenorhabditis lysozymes (Nematoda: Rhabditidae)
    • Schulenburg, H., Boehnisch, C., Diversification and adaptive sequence evolution of Caenorhabditis lysozymes (Nematoda: Rhabditidae). BMC Evol. Biol., 8, 2008, 114.
    • (2008) BMC Evol. Biol. , vol.8 , pp. 114
    • Schulenburg, H.1    Boehnisch, C.2
  • 61
    • 33749014641 scopus 로고    scopus 로고
    • A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
    • Shapira, M., Hamlin, B.J., Rong, J., Chen, K., Ronen, M., Tan, M.-W., A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 14086–14091.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 14086-14091
    • Shapira, M.1    Hamlin, B.J.2    Rong, J.3    Chen, K.4    Ronen, M.5    Tan, M.-W.6
  • 62
    • 80052644160 scopus 로고    scopus 로고
    • AMD, an automated motif discovery tool using stepwise refinement of gapped consensuses
    • Shi, J., Yang, W., Chen, M., Du, Y., Zhang, J., Wang, K., AMD, an automated motif discovery tool using stepwise refinement of gapped consensuses. PLoS One, 6, 2011, e24576.
    • (2011) PLoS One , vol.6 , pp. e24576
    • Shi, J.1    Yang, W.2    Chen, M.3    Du, Y.4    Zhang, J.5    Wang, K.6
  • 64
    • 84864622015 scopus 로고    scopus 로고
    • Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways
    • Shore, D.E., Carr, C.E., Ruvkun, G., Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. PLoS Genet., 8, 2012, e1002792.
    • (2012) PLoS Genet. , vol.8 , pp. e1002792
    • Shore, D.E.1    Carr, C.E.2    Ruvkun, G.3
  • 65
    • 39149142575 scopus 로고    scopus 로고
    • CRISPR – a widespread system that provides acquired resistance against phages in bacteria and archaea
    • Sorek, R., Kunin, V., Hugenholtz, P., CRISPR – a widespread system that provides acquired resistance against phages in bacteria and archaea. Nat. Rev. Microbiol. 6 (2008), 181–186.
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 181-186
    • Sorek, R.1    Kunin, V.2    Hugenholtz, P.3
  • 66
    • 0035165576 scopus 로고    scopus 로고
    • WormBase: network access to the genome and biology of Caenorhabditis elegans
    • Stein, L., Sternberg, P., Durbin, R., Thierry-Mieg, J., Spieth, J., WormBase: network access to the genome and biology of Caenorhabditis elegans. Nucleic Acids Res. 29 (2001), 82–86.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 82-86
    • Stein, L.1    Sternberg, P.2    Durbin, R.3    Thierry-Mieg, J.4    Spieth, J.5
  • 68
    • 39049163024 scopus 로고    scopus 로고
    • Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site
    • Tabach, Y., Brosh, R., Buganim, Y., Reiner, A., Zuk, O., Yitzhaky, A., Koudritsky, M., Rotter, V., Domany, E., Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site. PLoS One, 2, 2007, e807.
    • (2007) PLoS One , vol.2 , pp. e807
    • Tabach, Y.1    Brosh, R.2    Buganim, Y.3    Reiner, A.4    Zuk, O.5    Yitzhaky, A.6    Koudritsky, M.7    Rotter, V.8    Domany, E.9
  • 69
    • 84881175076 scopus 로고    scopus 로고
    • PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
    • Tepper, R.G., Ashraf, J., Kaletsky, R., Kleemann, G., Murphy, C.T., Bussemaker, H.J., PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell 154 (2013), 676–690.
    • (2013) Cell , vol.154 , pp. 676-690
    • Tepper, R.G.1    Ashraf, J.2    Kaletsky, R.3    Kleemann, G.4    Murphy, C.T.5    Bussemaker, H.J.6
  • 70
    • 0038664127 scopus 로고    scopus 로고
    • Identification and functional analysis of human transcriptional promoters
    • Trinklein, N.D., Aldred, S.J.F., Saldanha, A.J., Myers, R.M., Identification and functional analysis of human transcriptional promoters. Genome Res. 13 (2003), 308–312.
    • (2003) Genome Res. , vol.13 , pp. 308-312
    • Trinklein, N.D.1    Aldred, S.J.F.2    Saldanha, A.J.3    Myers, R.M.4
  • 71
    • 33751382748 scopus 로고    scopus 로고
    • p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
    • Troemel, E.R., Chu, S.W., Reinke, V., Lee, S.S., Ausubel, F.M., Kim, D.H., p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet., 2, 2006, e183.
    • (2006) PLoS Genet. , vol.2 , pp. e183
    • Troemel, E.R.1    Chu, S.W.2    Reinke, V.3    Lee, S.S.4    Ausubel, F.M.5    Kim, D.H.6
  • 73
    • 84855263820 scopus 로고    scopus 로고
    • Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans
    • Van Der Hoeven, R., McCallum, K.C., Cruz, M.R., Garsin, D.A., Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans. PLoS Pathog., 7, 2011, e1002453.
    • (2011) PLoS Pathog. , vol.7 , pp. e1002453
    • Van Der Hoeven, R.1    McCallum, K.C.2    Cruz, M.R.3    Garsin, D.A.4
  • 75
    • 41549093748 scopus 로고    scopus 로고
    • Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection
    • Wong, D., Bazopoulou, D., Pujol, N., Tavernarakis, N., Ewbank, J.J., Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection. Genome Biol., 8, 2007, R194.
    • (2007) Genome Biol. , vol.8 , pp. R194
    • Wong, D.1    Bazopoulou, D.2    Pujol, N.3    Tavernarakis, N.4    Ewbank, J.J.5
  • 76
    • 84924237678 scopus 로고    scopus 로고
    • Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis
    • Yang, W., Dierking, K., Esser, D., Tholey, A., Leippe, M., Rosenstiel, P., Schulenburg, H., Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis. Dev. Comp. Immunol. 51 (2015), 1–9.
    • (2015) Dev. Comp. Immunol. , vol.51 , pp. 1-9
    • Yang, W.1    Dierking, K.2    Esser, D.3    Tholey, A.4    Leippe, M.5    Rosenstiel, P.6    Schulenburg, H.7
  • 77
    • 84962166688 scopus 로고    scopus 로고
    • WormExp: a web-based application for a Caenorhabditis elegans-specific gene expression enrichment analysis
    • Yang, W., Dierking, K., Schulenburg, H., WormExp: a web-based application for a Caenorhabditis elegans-specific gene expression enrichment analysis. Bioinformatics 15 (2015), 943–945.
    • (2015) Bioinformatics , vol.15 , pp. 943-945
    • Yang, W.1    Dierking, K.2    Schulenburg, H.3
  • 78
    • 84872143888 scopus 로고    scopus 로고
    • Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators
    • Zhang, P., Judy, M., Lee, S.-J., Kenyon, C., Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators. Cell Metab. 17 (2013), 85–100.
    • (2013) Cell Metab. , vol.17 , pp. 85-100
    • Zhang, P.1    Judy, M.2    Lee, S.-J.3    Kenyon, C.4
  • 80
    • 84906222430 scopus 로고    scopus 로고
    • Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans
    • Zugasti, O., Bose, N., Squiban, B., Belougne, J., Kurz, C.L., Schroeder, F.C., Pujol, N., Ewbank, J.J., Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Nature Immunol. 15 (2014), 833–838.
    • (2014) Nature Immunol. , vol.15 , pp. 833-838
    • Zugasti, O.1    Bose, N.2    Squiban, B.3    Belougne, J.4    Kurz, C.L.5    Schroeder, F.C.6    Pujol, N.7    Ewbank, J.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.