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Volumn 11, Issue 5, 2015, Pages

The Developmental Intestinal Regulator ELT-2 Controls p38-Dependent Immune Responses in Adult C. elegans

Author keywords

[No Author keywords available]

Indexed keywords

SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATF 7; TRANSCRIPTION FACTOR ELT 2; TRANSCRIPTION FACTOR SKN 1; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR; ATF-7 PROTEIN, C ELEGANS; CAENORHABDITIS ELEGANS PROTEIN; DNA BINDING PROTEIN; ELT-2 PROTEIN, C ELEGANS; MITOGEN ACTIVATED PROTEIN KINASE P38; SKN-1 PROTEIN, C ELEGANS; TRANSCRIPTION FACTOR GATA;

EID: 84930815231     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005265     Document Type: Article
Times cited : (41)

References (54)
  • 1
    • 27144540463 scopus 로고    scopus 로고
    • Are innate immune signaling pathways in plants and animals conserved?
    • Ausubel FM, (2005) Are innate immune signaling pathways in plants and animals conserved? Nat Immunol 6: 973–979. 16177805
    • (2005) Nat Immunol , vol.6 , pp. 973-979
    • Ausubel, F.M.1
  • 2
    • 84864267865 scopus 로고    scopus 로고
    • Mice, men and the relatives: cross-species studies underpin innate immunity
    • Bryant CE, Monie TP, (2012) Mice, men and the relatives: cross-species studies underpin innate immunity. Open Biol 2: 120015. doi: 10.1098/rsob.120015 22724060
    • (2012) Open Biol , vol.2 , pp. 120015
    • Bryant, C.E.1    Monie, T.P.2
  • 3
    • 84905505984 scopus 로고    scopus 로고
    • Killing two birds with one stone: trans-kingdom suppression of PAMP/MAMP-induced immunity by T3E from enteropathogenic bacteria
    • Fraiture M, Brunner F, (2014) Killing two birds with one stone: trans-kingdom suppression of PAMP/MAMP-induced immunity by T3E from enteropathogenic bacteria. Front Microbiol 5: 320. doi: 10.3389/fmicb.2014.00320 25101059
    • (2014) Front Microbiol , vol.5 , pp. 320
    • Fraiture, M.1    Brunner, F.2
  • 4
    • 0037178731 scopus 로고    scopus 로고
    • A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity
    • Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, et al. (2002) A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297: 623–626. 12142542
    • (2002) Science , vol.297 , pp. 623-626
    • Kim, D.H.1    Feinbaum, R.2    Alloing, G.3    Emerson, F.E.4    Garsin, D.A.5
  • 5
    • 72949096858 scopus 로고    scopus 로고
    • Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates
    • Irazoqui JE, Urbach JM, Ausubel FM, (2010) Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat Rev Immunol 10: 47–58. doi: 10.1038/nri2689 20029447
    • (2010) Nat Rev Immunol , vol.10 , pp. 47-58
    • Irazoqui, J.E.1    Urbach, J.M.2    Ausubel, F.M.3
  • 6
    • 79952634846 scopus 로고    scopus 로고
    • Genetic and molecular analysis of nematode-microbe interactions
    • Tan MW, Shapira M, (2011) Genetic and molecular analysis of nematode-microbe interactions. Cell Microbiol.
    • (2011) Cell Microbiol
    • Tan, M.W.1    Shapira, M.2
  • 7
    • 84883199752 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in innate immunity
    • Arthur JS, Ley SC, (2013) Mitogen-activated protein kinases in innate immunity. Nat Rev Immunol 13: 679–692. doi: 10.1038/nri3495 23954936
    • (2013) Nat Rev Immunol , vol.13 , pp. 679-692
    • Arthur, J.S.1    Ley, S.C.2
  • 8
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, et al. (2004) TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat Immunol 5: 488–494. 15048112
    • (2004) Nat Immunol , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5
  • 9
    • 2342475724 scopus 로고    scopus 로고
    • Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response
    • Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, et al. (2004) Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc Natl Acad Sci U S A 101: 6593–6598. 15123841
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6593-6598
    • Liberati, N.T.1    Fitzgerald, K.A.2    Kim, D.H.3    Feinbaum, R.4    Golenbock, D.T.5
  • 10
    • 3342899839 scopus 로고    scopus 로고
    • Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase
    • Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, et al. (2004) Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc Natl Acad Sci U S A 101: 10990–10994. 15256594
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10990-10994
    • Kim, D.H.1    Liberati, N.T.2    Mizuno, T.3    Inoue, H.4    Hisamoto, N.5
  • 11
    • 77952376722 scopus 로고    scopus 로고
    • Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans
    • Shivers RP, Pagano DJ, Kooistra T, Richardson CE, Reddy KC, et al. (2010) Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans. PLoS Genet 6: e1000892. doi: 10.1371/journal.pgen.1000892 20369020
    • (2010) PLoS Genet , vol.6 , pp. e1000892
    • Shivers, R.P.1    Pagano, D.J.2    Kooistra, T.3    Richardson, C.E.4    Reddy, K.C.5
  • 12
    • 84875977306 scopus 로고    scopus 로고
    • RFX transcription factor DAF-19 regulates 5-HT and innate immune responses to pathogenic bacteria in Caenorhabditis elegans
    • Xie Y, Moussaif M, Choi S, Xu L, Sze JY, (2013) RFX transcription factor DAF-19 regulates 5-HT and innate immune responses to pathogenic bacteria in Caenorhabditis elegans. PLoS Genet 9: e1003324. doi: 10.1371/journal.pgen.1003324 23505381
    • (2013) PLoS Genet , vol.9 , pp. e1003324
    • Xie, Y.1    Moussaif, M.2    Choi, S.3    Xu, L.4    Sze, J.Y.5
  • 13
    • 25844490465 scopus 로고    scopus 로고
    • The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
    • Inoue H, Hisamoto N, An JH, Oliveira RP, Nishida E, et al. (2005) The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev 19: 2278–2283. 16166371
    • (2005) Genes Dev , vol.19 , pp. 2278-2283
    • Inoue, H.1    Hisamoto, N.2    An, J.H.3    Oliveira, R.P.4    Nishida, E.5
  • 14
    • 84855263820 scopus 로고    scopus 로고
    • Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans
    • Hoeven R, McCallum KC, Cruz MR, Garsin DA, (2011) Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans. PLoS Pathog 7: e1002453. doi: 10.1371/journal.ppat.1002453 22216003
    • (2011) PLoS Pathog , vol.7 , pp. e1002453
    • Hoeven, R.1    McCallum, K.C.2    Cruz, M.R.3    Garsin, D.A.4
  • 15
    • 84861215311 scopus 로고    scopus 로고
    • A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans
    • Papp D, Csermely P, Soti C, (2012) A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans. PLoS Pathog 8: e1002673. doi: 10.1371/journal.ppat.1002673 22577361
    • (2012) PLoS Pathog , vol.8 , pp. e1002673
    • Papp, D.1    Csermely, P.2    Soti, C.3
  • 16
    • 48249137383 scopus 로고    scopus 로고
    • Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides
    • Pujol N, Zugasti O, Wong D, Couillault C, Kurz CL, et al. (2008) Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides. PLoS Pathog 4: e1000105. doi: 10.1371/journal.ppat.1000105 18636113
    • (2008) PLoS Pathog , vol.4 , pp. e1000105
    • Pujol, N.1    Zugasti, O.2    Wong, D.3    Couillault, C.4    Kurz, C.L.5
  • 17
    • 0035099449 scopus 로고    scopus 로고
    • Activation of hypodermal differentiation in the Caenorhabditis elegans embryo by GATA transcription factors ELT-1 and ELT-3
    • Gilleard JS, McGhee JD, (2001) Activation of hypodermal differentiation in the Caenorhabditis elegans embryo by GATA transcription factors ELT-1 and ELT-3. Mol Cell Biol 21: 2533–2544. 11259601
    • (2001) Mol Cell Biol , vol.21 , pp. 2533-2544
    • Gilleard, J.S.1    McGhee, J.D.2
  • 18
    • 0032526161 scopus 로고    scopus 로고
    • The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
    • Fukushige T, Hawkins MG, McGhee JD, (1998) The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev Biol 198: 286–302. 9659934
    • (1998) Dev Biol , vol.198 , pp. 286-302
    • Fukushige, T.1    Hawkins, M.G.2    McGhee, J.D.3
  • 19
    • 33846818720 scopus 로고    scopus 로고
    • The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine
    • McGhee JD, Sleumer MC, Bilenky M, Wong K, McKay SJ, et al. (2007) The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. Dev Biol 302: 627–645. 17113066
    • (2007) Dev Biol , vol.302 , pp. 627-645
    • McGhee, J.D.1    Sleumer, M.C.2    Bilenky, M.3    Wong, K.4    McKay, S.J.5
  • 20
    • 60549094760 scopus 로고    scopus 로고
    • ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult
    • McGhee JD, Fukushige T, Krause MW, Minnema SE, Goszczynski B, et al. (2009) ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult. Dev Biol 327: 551–565. doi: 10.1016/j.ydbio.2008.11.034 19111532
    • (2009) Dev Biol , vol.327 , pp. 551-565
    • McGhee, J.D.1    Fukushige, T.2    Krause, M.W.3    Minnema, S.E.4    Goszczynski, B.5
  • 21
    • 77957316866 scopus 로고    scopus 로고
    • Endoderm development in Caenorhabditis elegans: the synergistic action of ELT-2 and -7 mediates the specification—>differentiation transition
    • Sommermann EM, Strohmaier KR, Maduro MF, Rothman JH, (2010) Endoderm development in Caenorhabditis elegans: the synergistic action of ELT-2 and -7 mediates the specification—>differentiation transition. Dev Biol 347: 154–166. doi: 10.1016/j.ydbio.2010.08.020 20807527
    • (2010) Dev Biol , vol.347 , pp. 154-166
    • Sommermann, E.M.1    Strohmaier, K.R.2    Maduro, M.F.3    Rothman, J.H.4
  • 22
    • 33749014641 scopus 로고    scopus 로고
    • A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
    • Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, et al. (2006) A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc Natl Acad Sci U S A 103: 14086–14091. 16968778
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14086-14091
    • Shapira, M.1    Hamlin, B.J.2    Rong, J.3    Chen, K.4    Ronen, M.5
  • 23
    • 54949117914 scopus 로고    scopus 로고
    • GATA transcription factor required for immunity to bacterial and fungal pathogens
    • Kerry S, TeKippe M, Gaddis NC, Aballay A, (2006) GATA transcription factor required for immunity to bacterial and fungal pathogens. PLoS ONE 1: e77. 17183709
    • (2006) PLoS ONE , vol.1 , pp. e77
    • Kerry, S.1    TeKippe, M.2    Gaddis, N.C.3    Aballay, A.4
  • 24
    • 84883764681 scopus 로고    scopus 로고
    • Burkholderia pseudomallei suppresses Caenorhabditis elegans immunity by specific degradation of a GATA transcription factor
    • Lee SH, Wong RR, Chin CY, Lim TY, Eng SA, et al. (2013) Burkholderia pseudomallei suppresses Caenorhabditis elegans immunity by specific degradation of a GATA transcription factor. Proc Natl Acad Sci U S A 110: 15067–15072. doi: 10.1073/pnas.1311725110 23980181
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 15067-15072
    • Lee, S.H.1    Wong, R.R.2    Chin, C.Y.3    Lim, T.Y.4    Eng, S.A.5
  • 25
    • 0033565677 scopus 로고    scopus 로고
    • Serpent regulates Drosophila immunity genes in the larval fat body through an essential GATA motif
    • Petersen UM, Kadalayil L, Rehorn KP, Hoshizaki DK, Reuter R, et al. (1999) Serpent regulates Drosophila immunity genes in the larval fat body through an essential GATA motif. Embo J 18: 4013–4022. 10406806
    • (1999) Embo J , vol.18 , pp. 4013-4022
    • Petersen, U.M.1    Kadalayil, L.2    Rehorn, K.P.3    Hoshizaki, D.K.4    Reuter, R.5
  • 26
    • 0034671733 scopus 로고    scopus 로고
    • The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression
    • Molkentin JD, (2000) The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem 275: 38949–38952. 11042222
    • (2000) J Biol Chem , vol.275 , pp. 38949-38952
    • Molkentin, J.D.1
  • 27
  • 28
    • 2642568647 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart
    • Tenhunen O, Sarman B, Kerkela R, Szokodi I, Papp L, et al. (2004) Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart. J Biol Chem 279: 24852–24860. 15051723
    • (2004) J Biol Chem , vol.279 , pp. 24852-24860
    • Tenhunen, O.1    Sarman, B.2    Kerkela, R.3    Szokodi, I.4    Papp, L.5
  • 29
    • 84891553013 scopus 로고    scopus 로고
    • GATA factors promote ER integrity and beta-cell survival and contribute to type 1 diabetes risk
    • Sartori DJ, Wilbur CJ, Long SY, Rankin MM, Li C, et al. (2014) GATA factors promote ER integrity and beta-cell survival and contribute to type 1 diabetes risk. Mol Endocrinol 28: 28–39. doi: 10.1210/me.2013-1265 24284823
    • (2014) Mol Endocrinol , vol.28 , pp. 28-39
    • Sartori, D.J.1    Wilbur, C.J.2    Long, S.Y.3    Rankin, M.M.4    Li, C.5
  • 30
    • 79954425693 scopus 로고    scopus 로고
    • Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis
    • Suzuki YJ, (2011) Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis. Cell Signal 23: 1094–1099. doi: 10.1016/j.cellsig.2011.02.007 21376121
    • (2011) Cell Signal , vol.23 , pp. 1094-1099
    • Suzuki, Y.J.1
  • 31
    • 32244446124 scopus 로고    scopus 로고
    • Chromosomal clustering and GATA transcriptional regulation of intestine-expressed genes in C. elegans
    • Pauli F, Liu Y, Kim YA, Chen PJ, Kim SK, (2006) Chromosomal clustering and GATA transcriptional regulation of intestine-expressed genes in C. elegans. Development 133: 287–295. 16354718
    • (2006) Development , vol.133 , pp. 287-295
    • Pauli, F.1    Liu, Y.2    Kim, Y.A.3    Chen, P.J.4    Kim, S.K.5
  • 32
    • 0037194732 scopus 로고    scopus 로고
    • Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans
    • Roy PJ, Stuart JM, Lund J, Kim SK, (2002) Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans. Nature 418: 975–979. 12214599
    • (2002) Nature , vol.418 , pp. 975-979
    • Roy, P.J.1    Stuart, J.M.2    Lund, J.3    Kim, S.K.4
  • 33
    • 1942453792 scopus 로고    scopus 로고
    • The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413
    • Bossinger O, Fukushige T, Claeys M, Borgonie G, McGhee JD, (2004) The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413. Dev Biol 268: 448–456. 15063180
    • (2004) Dev Biol , vol.268 , pp. 448-456
    • Bossinger, O.1    Fukushige, T.2    Claeys, M.3    Borgonie, G.4    McGhee, J.D.5
  • 34
    • 41649104468 scopus 로고    scopus 로고
    • Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans
    • Schulenburg H, Hoeppner MP, Weiner J, 3rdBornberg-Bauer E, (2008) Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Immunobiology 213: 237–250. doi: 10.1016/j.imbio.2007.12.004 18406370
    • (2008) Immunobiology , vol.213 , pp. 237-250
    • Schulenburg, H.1    Hoeppner, M.P.2    Weiner, J.3    Bornberg-Bauer, E.4
  • 35
    • 0032693308 scopus 로고    scopus 로고
    • Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo
    • Fukushige T, Hendzel MJ, Bazett-Jones DP, McGhee JD, (1999) Direct visualization of the elt-2 gut-specific GATA factor binding to a target promoter inside the living Caenorhabditis elegans embryo. Proc Natl Acad Sci U S A 96: 11883–11888. 10518545
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11883-11888
    • Fukushige, T.1    Hendzel, M.J.2    Bazett-Jones, D.P.3    McGhee, J.D.4
  • 36
    • 33751382748 scopus 로고    scopus 로고
    • p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
    • Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, et al. (2006) p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet 2: e183. 17096597
    • (2006) PLoS Genet , vol.2 , pp. e183
    • Troemel, E.R.1    Chu, S.W.2    Reinke, V.3    Lee, S.S.4    Ausubel, F.M.5
  • 37
    • 79957992660 scopus 로고    scopus 로고
    • A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans
    • Youngman MJ, Rogers ZN, Kim DH, (2011) A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. PLoS Genet 7: e1002082. doi: 10.1371/journal.pgen.1002082 21625567
    • (2011) PLoS Genet , vol.7 , pp. e1002082
    • Youngman, M.J.1    Rogers, Z.N.2    Kim, D.H.3
  • 38
    • 79952581182 scopus 로고    scopus 로고
    • GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans
    • Hahm JH, Kim S, Paik YK, (2011) GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans. Aging Cell 10: 208–219. doi: 10.1111/j.1474-9726.2010.00655.x 21108728
    • (2011) Aging Cell , vol.10 , pp. 208-219
    • Hahm, J.H.1    Kim, S.2    Paik, Y.K.3
  • 39
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • Bishop NA, Guarente L, (2007) Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447: 545–549. 17538612
    • (2007) Nature , vol.447 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 40
    • 78650410139 scopus 로고    scopus 로고
    • Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
    • Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, et al. (2010) Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science 330: 1775–1787. doi: 10.1126/science.1196914 21177976
    • (2010) Science , vol.330 , pp. 1775-1787
    • Gerstein, M.B.1    Lu, Z.J.2    Van Nostrand, E.L.3    Cheng, C.4    Arshinoff, B.I.5
  • 41
    • 33846935457 scopus 로고    scopus 로고
    • Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3
    • Maneechotesuwan K, Xin Y, Ito K, Jazrawi E, Lee KY, et al. (2007) Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3. J Immunol 178: 2491–2498. 17277157
    • (2007) J Immunol , vol.178 , pp. 2491-2498
    • Maneechotesuwan, K.1    Xin, Y.2    Ito, K.3    Jazrawi, E.4    Lee, K.Y.5
  • 42
    • 0035958845 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes
    • Morisco C, Seta K, Hardt SE, Lee Y, Vatner SF, et al. (2001) Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes. J Biol Chem 276: 28586–28597. 11382772
    • (2001) J Biol Chem , vol.276 , pp. 28586-28597
    • Morisco, C.1    Seta, K.2    Hardt, S.E.3    Lee, Y.4    Vatner, S.F.5
  • 43
    • 77956384716 scopus 로고    scopus 로고
    • Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans
    • Kawli T, Wu C, Tan MW, (2010) Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans. Proc Natl Acad Sci U S A 107: 13788–13793. doi: 10.1073/pnas.0914715107 20647387
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13788-13793
    • Kawli, T.1    Wu, C.2    Tan, M.W.3
  • 44
    • 84863995580 scopus 로고    scopus 로고
    • An age-dependent reversal in the protective capacities of JNK signaling shortens C. elegans lifespan
    • Twumasi-Boateng K, Wang TW, Tsai L, Lee KH, Salehpour A, et al. (2012) An age-dependent reversal in the protective capacities of JNK signaling shortens C. elegans lifespan. Aging Cell.
    • (2012) Aging Cell
    • Twumasi-Boateng, K.1    Wang, T.W.2    Tsai, L.3    Lee, K.H.4    Salehpour, A.5
  • 46
    • 0030249849 scopus 로고    scopus 로고
    • Superoxide production by the mycobacterial and pseudomonad quinoid pigments phthiocol and pyocyanine in human lung cells
    • Gardner PR, (1996) Superoxide production by the mycobacterial and pseudomonad quinoid pigments phthiocol and pyocyanine in human lung cells. Arch Biochem Biophys 333: 267–274. 8806780
    • (1996) Arch Biochem Biophys , vol.333 , pp. 267-274
    • Gardner, P.R.1
  • 47
    • 84881175076 scopus 로고    scopus 로고
    • PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
    • Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, et al. (2013) PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. Cell 154: 676–690. doi: 10.1016/j.cell.2013.07.006 23911329
    • (2013) Cell , vol.154 , pp. 676-690
    • Tepper, R.G.1    Ashraf, J.2    Kaletsky, R.3    Kleemann, G.4    Murphy, C.T.5
  • 48
    • 0033582314 scopus 로고    scopus 로고
    • Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis
    • Tan MW, Mahajan-Miklos S, Ausubel FM, (1999) Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc Natl Acad Sci U S A 96: 715–720. 9892699
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 715-720
    • Tan, M.W.1    Mahajan-Miklos, S.2    Ausubel, F.M.3
  • 49
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231–237. 12529635
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2    Dong, Y.3    Poulin, G.4    Durbin, R.5
  • 50
    • 45549093023 scopus 로고    scopus 로고
    • Genetic analysis of Caenorhabditis elegans innate immunity
    • Shapira M, Tan MW, (2008) Genetic analysis of Caenorhabditis elegans innate immunity. Methods Mol Biol 415: 429–442. doi: 10.1007/978-1-59745-570-1_25 18370169
    • (2008) Methods Mol Biol , vol.415 , pp. 429-442
    • Shapira, M.1    Tan, M.W.2
  • 51
    • 84859718267 scopus 로고    scopus 로고
    • Dissociation of Immune Responses from Pathogen Colonization Supports Pattern Recognition in C. elegans
    • Twumasi-Boateng K, Shapira M, (2012) Dissociation of Immune Responses from Pathogen Colonization Supports Pattern Recognition in C. elegans. PLoS ONE 7: e35400. doi: 10.1371/journal.pone.0035400 22514739
    • (2012) PLoS ONE , vol.7 , pp. e35400
    • Twumasi-Boateng, K.1    Shapira, M.2
  • 52
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G, (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116–5121. 11309499
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 54
    • 84890111590 scopus 로고    scopus 로고
    • A rapid protocol for integrating extrachromosomal arrays with high transmission rate into the C. elegans genome
    • Mariol MC, Walter L, Bellemin S, Gieseler K, (2013) A rapid protocol for integrating extrachromosomal arrays with high transmission rate into the C. elegans genome. J Vis Exp: e50773. doi: 10.3791/50773 24379027
    • (2013) J Vis Exp , pp. e50773
    • Mariol, M.C.1    Walter, L.2    Bellemin, S.3    Gieseler, K.4


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