Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

Aging

Volumn 8, Issue 6, 2016, Pages 1201-1222

  Reis, Felipe C G ^a   Branquinho, Jéssica L O ^a   Brandão, Bruna B ^a   Guerra, Beatriz A ^a   Silva, Ismael D ^a   Frontini, Andrea ^b   Thomou, Thomas ^c   Sartini, Loris ^d   Cinti, Saverio ^d   Ronald Kahn, C ^c   Festuccia, William T ^e   Kowaltowski, Alicia J ^e   Mori, Marcelo A ^a,f  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF PAVIA   (Italy)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Adipose tissue; Aging; Dicer; Dietary restriction; Insulin resistance

Indexed keywords

DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN; RIBONUCLEASE III;

AGING; ANIMAL; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; INSULIN RESISTANCE; KNOCKOUT MOUSE; LONGEVITY; METABOLISM; METABOLOMICS; MITOCHONDRION; MOUSE; PHYSIOLOGY; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; AGING; ANIMALS; DEAD-BOX RNA HELICASES; ENERGY METABOLISM; INSULIN RESISTANCE; LONGEVITY; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; METABOLOMICS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUSCLE, SKELETAL; RIBONUCLEASE III; SIROLIMUS;

EID: 84977532338     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100970     Document Type: Article

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