Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

Journal of Clinical Investigation

Volumn 124, Issue 8, 2014, Pages 3339-3351

  Mori, Marcelo A ^a,b   Thomou, Thomas ^a   Boucher, Jeremie ^a,c   Lee, Kevin Y ^a   Lallukka, Susanna ^d,e   Kim, Jason K ^f   Torriani, Martin ^g   Yki Järvinen, Hannele ^f   Grinspoon, Steven K ^g   Cypess, Aaron M ^a   Kahn, C Ronald ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c ASTRAZENECA R AND D   (Sweden)

^d UNIVERSITY OF HELSINKI   (Finland)

^e MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^f UNIVERSITY OF MASSACHUSETTS   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; MICRORNA 346; MICRORNA 362; MICRORNA 365; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; DICER1 PROTEIN, HUMAN; DICER1 PROTEIN, MOUSE; RIBONUCLEASE III;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; INSULIN RESISTANCE; INTRAABDOMINAL FAT; KNOCKOUT MOUSE; LIPODYSTROPHY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROADIPOCYTE; RNA PROCESSING; SUBCUTANEOUS FAT; WHITE ADIPOSE TISSUE; ANIMAL; BROWN ADIPOCYTE; COHORT ANALYSIS; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DOWN REGULATION; ENERGY METABOLISM; FEMALE; GENETICS; HIV ASSOCIATED LIPODYSTROPHY; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; WHITE ADIPOCYTE;

ADIPOCYTES, BROWN; ADIPOCYTES, WHITE; ANIMALS; CELL DIFFERENTIATION; COHORT STUDIES; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENERGY METABOLISM; FEMALE; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; INSULIN RESISTANCE; LIPODYSTROPHY; MALE; MICE; MICE, KNOCKOUT; MICRORNAS; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL;

EID: 84905455013     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI73468     Document Type: Article

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