Light-triggered RNA release and induction of hMSC osteogenesis via photodegradable, dual-crosslinked hydrogels

Nanomedicine

Volumn 11, Issue 12, 2016, Pages 1535-1550

  Huynh, Cong Truc ^a   Nguyen, Minh Khanh ^a   Naris, Mantas ^a   Tonga, Gulen Yesilbag ^c   Rotello, Vincent M ^c   Alsberg, Eben ^a,b  

^a Case Western Reserve University   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bone tissue engineering; in situ forming hydrogel; miRNA; on demand release; photolabile hydrogels; siRNA; stem cell differentiation; UV controllable release

Indexed keywords

GREEN FLUORESCENT PROTEIN; MACROGOL; MICRORNA 20A; NOGGIN; POLYETHYLENEIMINE; SMALL INTERFERING RNA; DELAYED RELEASE FORMULATION; HYDROGEL; MICRORNA; MIRN20 MICRORNA, HUMAN;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; GENE SILENCING; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROGEL; MESENCHYMAL STEM CELL; PHOTODEGRADATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; ULTRAVIOLET RADIATION; CELL LINE; CHEMISTRY; CYTOLOGY; DELAYED RELEASE FORMULATION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHOTOLYSIS; TISSUE ENGINEERING;

CELL DIFFERENTIATION; CELL LINE; DELAYED-ACTION PREPARATIONS; HELA CELLS; HUMANS; HYDROGELS; MESENCHYMAL STROMAL CELLS; MICRORNAS; OSTEOGENESIS; PHOTOLYSIS; RNA, SMALL INTERFERING; TISSUE ENGINEERING; ULTRAVIOLET RAYS;

EID: 84977523148     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm-2016-0088     Document Type: Article

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