The use of gene activated matrix to mediate effective SMAD2 gene silencing against hypertrophic scar

Biomaterials

Volumn 35, Issue 8, 2014, Pages 2488-2498

  Yin, Lichen ^a,c   Zhao, Xin ^a,d   Ji, Shizhao ^b   He, Chunbai ^a,e   Wang, Guangyi ^b   Tang, Cui ^a   Gu, Shaohua ^a   Yin, Chunhua ^a  

^a FUDAN UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c United States of America   (United States)

^d Shanghai Institute of Biological Products Co Ltd   (China)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

Atelocollagen; Gene activated matrix (GAM); Hypertrophic scar; RNA interference (RNAi); Thiolated trimethyl chitosan

Indexed keywords

ATELOCOLLAGEN; GENE-ACTIVATED MATRIX; HYPERTROPHIC SCAR; RNA INTERFERENCE; TRIMETHYL CHITOSAN;

AMINO ACIDS; CELL CULTURE; CELL PROLIFERATION; CHITOSAN; FIBROBLASTS; MOLECULAR BIOLOGY; RNA; SCAFFOLDS (BIOLOGY); THREE DIMENSIONAL;

GENES;

ATELOCOLLAGEN; CYSTEINE; PLASMID DNA; SMAD2 PROTEIN; SMALL INTERFERING RNA; TRIMETHYLCHITOSANCYSTEINE; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE ACTIVATED MATRIX; GENE ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; POROSITY; PRIORITY JOURNAL; RNA INTERFERENCE; SKIN FIBROBLAST;

ATELOCOLLAGEN; GENE ACTIVATED MATRIX (GAM); HYPERTROPHIC SCAR; RNA INTERFERENCE (RNAI); THIOLATED TRIMETHYL CHITOSAN;

BASE SEQUENCE; CELL PROLIFERATION; CICATRIX, HYPERTROPHIC; COLLAGEN; DNA; DOWN-REGULATION; FIBROBLASTS; HUMANS; MOLECULAR SEQUENCE DATA; PLASMIDS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SKIN; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84891740561     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.015     Document Type: Article

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