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Volumn 28, Issue 6, 2011, Pages 1328-1337

Non-viral delivery of inductive and suppressive genes to adipose-derived stem cells for osteogenic differentiation

Author keywords

BMP2; combinatorial; gene delivery; GNAS; Noggin

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; DNA; LIPID; NOGGIN; OSTEOCALCIN; POLY(BETA AMINO ESTER); SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 79959885948     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0406-9     Document Type: Article
Times cited : (28)

References (39)
  • 1
    • 0026609223 scopus 로고
    • Nontraumatic necrosis of bone (Osteonecrosis)
    • 1574093 10.1056/NEJM199205283262206 1:STN:280:DyaK383ksVeisg%3D%3D
    • HJ Mankin 1992 Nontraumatic necrosis of bone (Osteonecrosis) New Engl J Med 326 22 1473 1479 1574093 10.1056/NEJM199205283262206 1:STN:280: DyaK383ksVeisg%3D%3D
    • (1992) New Engl J Med , vol.326 , Issue.22 , pp. 1473-1479
    • Mankin, H.J.1
  • 2
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: Implications for cell-based therapies
    • DOI 10.1089/107632701300062859
    • PA Zuk M Zhu H Mizuno J Huang JW Futrell AJ Katz P Benhaim HP Lorenz MH Hedrick 2001 Multilineage cells from human adipose tissue: implications for cell-based therapies Tissue Eng 7 2 211 228 11304456 10.1089/107632701300062859 1:CAS:528:DC%2BD3MXjsFShtro%3D (Pubitemid 32295155)
    • (2001) Tissue Engineering , vol.7 , Issue.2 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3    Huang, J.4    Futrell, J.W.5    Katz, A.J.6    Benhaim, P.7    Lorenz, H.P.8    Hedrick, M.H.9
  • 4
    • 77953028086 scopus 로고    scopus 로고
    • Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells
    • 20413153 10.1016/j.biomaterials.2010.03.019 1:CAS:528: DC%2BC3cXmtlKiurg%3D
    • SJ Lee SW Kang HJ Do I Han DA Shin JH Kim SH Lee 2010 Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells Biomaterials 31 21 5652 5659 20413153 10.1016/j.biomaterials.2010.03.019 1:CAS:528:DC%2BC3cXmtlKiurg%3D
    • (2010) Biomaterials , vol.31 , Issue.21 , pp. 5652-5659
    • Lee, S.J.1    Kang, S.W.2    Do, H.J.3    Han, I.4    Shin, D.A.5    Kim, J.H.6    Lee, S.H.7
  • 5
    • 34147107634 scopus 로고    scopus 로고
    • Concise review: Adipose tissue-derived stromal cells - Basic and clinical implications for novel cell-based therapies
    • DOI 10.1634/stemcells.2006-0589
    • A Schaffler C Buchler 2007 Concise review: adipose tissue-derived stromal cells-basic and clinical implications for novel cell-based therapies Stem Cells 25 4 818 827 17420225 10.1634/stemcells.2006-0589 (Pubitemid 46572577)
    • (2007) Stem Cells , vol.25 , Issue.4 , pp. 818-827
    • Schaffler, A.1    Buchler, C.2
  • 7
    • 48749124949 scopus 로고    scopus 로고
    • In vivo bone formation following transplantation of human adipose-derived stromal cells that are not differentiated osteogenically
    • 10.1089/ten.tea.2007.0253 1:CAS:528:DC%2BD1cXpsFKrtb0%3D
    • J Jeon JW Rhie IK Kwon JH Kim BS Kim SH Lee 2008 In vivo bone formation following transplantation of human adipose-derived stromal cells that are not differentiated osteogenically Tissue Eng A 14 8 1285 1294 10.1089/ten.tea.2007. 0253 1:CAS:528:DC%2BD1cXpsFKrtb0%3D
    • (2008) Tissue Eng A , vol.14 , Issue.8 , pp. 1285-1294
    • Jeon, J.1    Rhie, J.W.2    Kwon, I.K.3    Kim, J.H.4    Kim, B.S.5    Lee, S.H.6
  • 8
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • 5319761 10.1126/science.150.3698.893 1:STN:280:DyaF28%2FhvFekuw%3D%3D
    • MR Urist 1965 Bone: formation by autoinduction Science 150 698 893 899 5319761 10.1126/science.150.3698.893 1:STN:280:DyaF28%2FhvFekuw%3D%3D
    • (1965) Science , vol.150 , Issue.698 , pp. 893-899
    • Urist, M.R.1
  • 9
    • 1342285045 scopus 로고    scopus 로고
    • Osteoarthritis gene therapy
    • DOI 10.1038/sj.gt.3302196, Gene Therapy for Orthopaedics
    • CH Evans JN Gouze E Gouze PD Robbins SC Ghivizzani 2004 Osteoarthritis gene therapy Gene Ther 11 4 379 389 14724685 10.1038/sj.gt.3302196 1:CAS:528:DC%2BD2cXpsFSntw%3D%3D (Pubitemid 38263088)
    • (2004) Gene Therapy , vol.11 , Issue.4 , pp. 379-389
    • Evans, C.H.1    Gouze, J.N.2    Gouze, E.3    Robbins, P.D.4    Ghivizzani, S.C.5
  • 10
    • 34249306597 scopus 로고    scopus 로고
    • Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism
    • DOI 10.1111/j.1524-475X.2007.00228.x
    • SK Cheema E Chen LD Shea AB Mathur 2007 Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism Wound Repair Regen 15 3 286 295 17537114 10.1111/j.1524-475X.2007.00228.x (Pubitemid 46817403)
    • (2007) Wound Repair and Regeneration , vol.15 , Issue.3 , pp. 286-295
    • Cheema, S.K.1    Chen, E.2    Shea, L.D.3    Mathur, A.B.4
  • 11
    • 75749101014 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells
    • 20039267 1:CAS:528:DC%2BC3cXhtlSit7c%3D
    • Y Mikami M Asano MJ Honda M Takagi 2010 Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK/STAT signaling in C3H10T1/2 cells J Cell Physiol 223 1 123 133 20039267 1:CAS:528:DC%2BC3cXhtlSit7c%3D
    • (2010) J Cell Physiol , vol.223 , Issue.1 , pp. 123-133
    • Mikami, Y.1    Asano, M.2    Honda, M.J.3    Takagi, M.4
  • 12
    • 34547485288 scopus 로고    scopus 로고
    • A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells
    • DOI 10.1073/pnas.0703407104
    • Y Zhao S Ding 2007 A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells Proc Natl Acad Sci 104 23 9673 9678 17535907 10.1073/pnas.0703407104 1:CAS:528:DC%2BD2sXmsFWjtr4%3D (Pubitemid 47175325)
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.23 , pp. 9673-9678
    • Zhao, Y.1    Ding, S.2
  • 14
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • DOI 10.1038/nrg1066
    • CE Thomas A Ehrhardt MA Kay 2003 Progress and problems with the use of viral vectors for gene therapy Nat Rev Genet 4 5 346 358 12728277 10.1038/nrg1066 1:CAS:528:DC%2BD3sXjtlaksr4%3D (Pubitemid 36538359)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.5 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 16
    • 64549140262 scopus 로고    scopus 로고
    • Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors
    • 19129861 10.1038/gt.2008.182 1:CAS:528:DC%2BD1MXis1Oluw%3D%3D
    • F Yang JJ Green T Dinio L Keung SW Cho H Park, et al. 2009 Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors Gene Ther 16 4 533 546 19129861 10.1038/gt.2008.182 1:CAS:528:DC%2BD1MXis1Oluw%3D%3D
    • (2009) Gene Ther , vol.16 , Issue.4 , pp. 533-546
    • Yang, F.1    Green, J.J.2    Dinio, T.3    Keung, L.4    Cho, S.W.5    Park, H.6
  • 18
    • 70349687233 scopus 로고    scopus 로고
    • Lipid-like nanoparticles for small interfering RNA delivery to endothelial cells
    • 10.1002/adfm.200900519 1:CAS:528:DC%2BD1MXht1KisrrM
    • SW Cho M Goldberg SM Son Q Xu F Yang Y Mei, et al. 2009 Lipid-like nanoparticles for small interfering RNA delivery to endothelial cells Adv Funct Mater 19 19 3112 3118 10.1002/adfm.200900519 1:CAS:528:DC%2BD1MXht1KisrrM
    • (2009) Adv Funct Mater , vol.19 , Issue.19 , pp. 3112-3118
    • Cho, S.W.1    Goldberg, M.2    Son, S.M.3    Xu, Q.4    Yang, F.5    Mei, Y.6
  • 19
    • 20444395813 scopus 로고    scopus 로고
    • The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells
    • DOI 10.1016/j.biomaterials.2005.03.018, PII S0142961205002346
    • F Yang CG Williams DA Wang H Lee P Manson J Elisseeff 2005 The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells Biomaterials 26 30 5991 5998 15878198 10.1016/j.biomaterials.2005.03.018 1:CAS:528:DC%2BD2MXlt1Wgsbg%3D (Pubitemid 40805605)
    • (2005) Biomaterials , vol.26 , Issue.30 , pp. 5991-5998
    • Yang, F.1    Williams, C.G.2    Wang, D.-A.3    Lee, H.4    Manson, P.N.5    Elisseeff, J.6
  • 20
    • 77649262343 scopus 로고    scopus 로고
    • Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles
    • 19805054 10.1073/pnas.0905432106 1:CAS:528:DC%2BC3cXjtFymtL8%3D
    • F Yang SW Cho SM Son SR Bogatyrev D Singh JJ Green, et al. 2010 Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles Proc Natl Acad Sci 107 8 3317 3322 19805054 10.1073/pnas.0905432106 1:CAS:528:DC%2BC3cXjtFymtL8%3D
    • (2010) Proc Natl Acad Sci , vol.107 , Issue.8 , pp. 3317-3322
    • Yang, F.1    Cho, S.W.2    Son, S.M.3    Bogatyrev, S.R.4    Singh, D.5    Green, J.J.6
  • 21
    • 18144382322 scopus 로고    scopus 로고
    • Reduction in Gsα induces osteogenic differentiation in human mesenchymal stem cells
    • DOI 10.1097/01.blo.0000153279.90512.38
    • Lietman SA, Ding C, Cooke DW, Levine MA. Reduction in Gs[alpha] induces osteogenic differentiation in human mesenchymal stem cells. Clin Orthop Relat Res. 2005;(434):231-8. (Pubitemid 40617522)
    • (2005) Clinical Orthopaedics and Related Research , Issue.434 , pp. 231-238
    • Lietman, S.A.1    Ding, C.2    Cooke, D.W.3    Levine, M.A.4
  • 22
    • 22144447455 scopus 로고    scopus 로고
    • Design and development of polymers for gene delivery
    • DOI 10.1038/nrd1775
    • DW Pack AS Hoffman S Pun PS Stayton 2005 Design and development of polymers for gene delivery Nat Rev Drug Discov 4 7 581 593 16052241 10.1038/nrd1775 1:CAS:528:DC%2BD2MXmsFGjtbo%3D (Pubitemid 40975711)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.7 , pp. 581-593
    • Pack, D.W.1    Hoffman, A.S.2    Pun, S.3    Stayton, P.S.4
  • 24
    • 47249155205 scopus 로고    scopus 로고
    • A combinatorial polymer library approach yields insight into nonviral gene delivery
    • 10.1021/ar7002336 1:CAS:528:DC%2BD1cXmsVKht7o%3D
    • JJ Green R Langer DG Anderson 2008 A combinatorial polymer library approach yields insight into nonviral gene delivery Acc Chem Res 41 6 749 759 10.1021/ar7002336 1:CAS:528:DC%2BD1cXmsVKht7o%3D
    • (2008) Acc Chem Res , vol.41 , Issue.6 , pp. 749-759
    • Green, J.J.1    Langer, R.2    Anderson, D.G.3
  • 25
    • 14044277649 scopus 로고    scopus 로고
    • Lentivirus-mediated gene transfer induces long-term transgene expression of BMP-2 in vitro and new bone formation in vivo
    • DOI 10.1016/j.ymthe.2004.10.019, PII S1525001604015114
    • O Sugiyama DS An S Kung BT Feeley S Gamradt NQ Liu I Chen JR Liberman 2005 Lenti-virus-mediated gene transfer induces long-term transgene expression of BMP-2 in vitro and new bone formation in vivo Mol Ther 11 3 390 398 15727935 10.1016/j.ymthe.2004.10.019 1:CAS:528:DC%2BD2MXhsVOjurk%3D (Pubitemid 40277315)
    • (2005) Molecular Therapy , vol.11 , Issue.3 , pp. 390-398
    • Sugiyama, O.1    Sung An, D.2    Kung, S.P.K.3    Feeley, B.T.4    Gamradt, S.5    Liu, N.Q.6    Chen, I.S.Y.7    Lieberman, J.R.8
  • 26
    • 79959860290 scopus 로고    scopus 로고
    • Adipose-derived stem cells and BMP2: Part 2. BMP2 may not influence the osteogenic fate of human adipose-derived stem cells
    • Aug 11 (Epub ahead of print)
    • Zuk P, Chou YF, Mussano F, Benhaim P, Wu BM. Adipose-derived stem cells and BMP2: Part 2. BMP2 may not influence the osteogenic fate of human adipose-derived stem cells. Connect Tissue Res. 2010 Aug 11 (Epub ahead of print).
    • (2010) Connect Tissue Res.
    • Zuk, P.1    Chou, Y.F.2    Mussano, F.3    Benhaim, P.4    Wu, B.M.5
  • 27
    • 79952303073 scopus 로고    scopus 로고
    • Adipose-derived stem cells and BMP2: Part 1. BMP2-treated adipose-derived stem cells do not improve repair of segmental femoral defects
    • Aug 11. (Epub ahead of print)
    • Chou YF, Zuk P, Chang TL, Benhaim P, Wu BM. Adipose-derived stem cells and BMP2: Part 1. BMP2-treated adipose-derived stem cells do not improve repair of segmental femoral defects. Connect Tissue Res. 2010 Aug 11. (Epub ahead of print).
    • (2010) Connect Tissue Res.
    • Chou, Y.F.1    Zuk, P.2    Chang, T.L.3    Benhaim, P.4    Wu, B.M.5
  • 28
    • 33744785946 scopus 로고    scopus 로고
    • Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro
    • DOI 10.1016/j.bone.2005.12.018, PII S8756328206000032
    • W Zhu J Kim C Cheng BA Rawlins O Boachie-Adjei RG Crystal C Hidaka 2006 Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer acitivty in vitro Bone 39 1 61 71 16488673 10.1016/j.bone.2005.12.018 1:CAS:528:DC%2BD28Xls1ejtrY%3D (Pubitemid 43831779)
    • (2006) Bone , vol.39 , Issue.1 , pp. 61-71
    • Zhu, W.1    Kim, J.2    Cheng, C.3    Rawlins, B.A.4    Boachie-Adjei, O.5    Crystal, R.G.6    Hidaka, C.7
  • 29
    • 0042807407 scopus 로고    scopus 로고
    • In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation
    • S Yang D Wei D Wang M Phimphilai PH Krebsbach RT Franceschi 2003 In vitro and in vivo synergistic interactions between Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation J Bone Miner Res 18 4 705 715 12674331 10.1359/jbmr.2003.18.4.705 1:CAS:528:DC%2BD3sXivFKks7o%3D (Pubitemid 36899320)
    • (2003) Journal of Bone and Mineral Research , vol.18 , Issue.4 , pp. 705-715
    • Yang, S.1    Wei, D.2    Wang, D.3    Phimphilai, M.4    Krebsbach, P.H.5    Franceschi, R.T.6
  • 30
    • 33749468886 scopus 로고    scopus 로고
    • Runx2 regulates the expression of GNAS on SaOs-2 cells
    • DOI 10.1016/j.bone.2005.11.025, PII S8756328205004837
    • K Bertaux O Broux C Chauveau P Hardouin J Jeanfils JC Devedjian 2006 Runx2 regulates the expression of GNAS on SaOs-2 cells Bone 38 6 943 950 16442859 10.1016/j.bone.2005.11.025 1:CAS:528:DC%2BD28XlsVemsLw%3D (Pubitemid 44515037)
    • (2006) Bone , vol.38 , Issue.6 , pp. 943-950
    • Bertaux, K.1    Broux, O.2    Chauveau, C.3    Hardouin, P.4    Jeanfils, J.5    Devedjian, J.-C.6
  • 31
    • 0034460993 scopus 로고    scopus 로고
    • Runx2 is a common target of transforming growth factor β1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
    • DOI 10.1128/MCB.20.23.8783-8792.2000
    • KS Lee HJ Kim QL Li XZ Chi C Ueta T Komori, et al. 2000 Runx2 is a common target of transforming growth factor beta 1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12 Mol Cell Biol 20 23 8783 8792 11073979 10.1128/MCB.20.23.8783-8792.2000 1:CAS:528:DC%2BD3MXitFGrsr4%3D (Pubitemid 32245911)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.23 , pp. 8783-8792
    • Lee, K.-S.1    Kim, H.-J.2    Li, Q.-L.3    Chi, X.-Z.4    Ueta, C.5    Komori, T.6    Wozney, J.M.7    Kim, E.-G.8    Choi, J.-Y.9    Ryoo, H.-M.10    Bae, S.-C.11
  • 33
    • 0030794270 scopus 로고    scopus 로고
    • Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex
    • DOI 10.1002/(SICI)1097-4644(19970701)66:1<1::AID-JCB1>3.0.CO;2-V
    • C Banerjee LR McCabe JY Choi SW Hiebert JL Stein GS Stein JB Lian 1997 Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex J Cell Biochem 66 1 1 8 9215522 10.1002/(SICI)1097-4644(19970701)66:1<1::AID-JCB1>3.0.CO;2-V 1:CAS:528:DyaK2sXktl2isL0%3D (Pubitemid 27284091)
    • (1997) Journal of Cellular Biochemistry , vol.66 , Issue.1 , pp. 1-8
    • Banerjee, C.1    McCabe, L.R.2    Choi, J.-Y.3    Hiebert, S.W.4    Stein, J.L.5    Stein, G.S.6    Lian, J.B.7
  • 34
    • 0028927556 scopus 로고
    • Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene
    • 7891679 1:CAS:528:DyaK2MXksFWjsb4%3D
    • P Ducy G Karsenty 1995 Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene Mol Cell Biol 15 4 1858 1869 7891679 1:CAS:528:DyaK2MXksFWjsb4%3D
    • (1995) Mol Cell Biol , vol.15 , Issue.4 , pp. 1858-1869
    • Ducy, P.1    Karsenty, G.2
  • 35
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • P Ducy R Zhang V Geoffroy AL Ridall G Karsenty 1997 Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 5 747 754 9182762 10.1016/S0092-8674(00)80257-3 1:CAS:528:DyaK2sXjs1ejsbg%3D (Pubitemid 27516177)
    • (1997) Cell , vol.89 , Issue.5 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 36
    • 0029759907 scopus 로고    scopus 로고
    • Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages
    • Y Isogai T Akatsu T Ishizuya A Yamaguchi M Hori N Takahashi T Suda 1996 Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages J Bone Miner Res 11 10 1384 1393 8889836 10.1002/jbmr.5650111003 1:CAS:528:DyaK28XmsValtL8%3D (Pubitemid 26330991)
    • (1996) Journal of Bone and Mineral Research , vol.11 , Issue.10 , pp. 1384-1393
    • Isogai, Y.1    Akatsu, T.2    Ishizuya, T.3    Yamaguchi, A.4    Hori, M.5    Takahashi, N.6    Suda, T.7
  • 37
    • 0023732819 scopus 로고
    • Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor
    • 3166460 1:CAS:528:DyaL1cXlvVChsL0%3D
    • M Noda K Yoon CW Prince WT Butler GA Rodan 1988 Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor J Biol Chem 263 27 13916 13921 3166460 1:CAS:528:DyaL1cXlvVChsL0%3D
    • (1988) J Biol Chem , vol.263 , Issue.27 , pp. 13916-13921
    • Noda, M.1    Yoon, K.2    Prince, C.W.3    Butler, W.T.4    Rodan, G.A.5
  • 39
    • 43749091299 scopus 로고    scopus 로고
    • Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal
    • 18204048 10.1074/jbc.M705578200 1:CAS:528:DC%2BD1cXjsFCgsL0%3D
    • A Javed JS Bae F Afzal S Gutierrez J Pratap SK Zaidi, et al. 2008 Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal J Biol Chem 283 13 8412 8422 18204048 10.1074/jbc.M705578200 1:CAS:528:DC%2BD1cXjsFCgsL0%3D
    • (2008) J Biol Chem , vol.283 , Issue.13 , pp. 8412-8422
    • Javed, A.1    Bae, J.S.2    Afzal, F.3    Gutierrez, S.4    Pratap, J.5    Zaidi, S.K.6


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