Thermosensitive hydrogels based on polypeptides for localized and sustained delivery of anticancer drugs

Biomaterials

Volumn 34, Issue 38, 2013, Pages 10338-10347

  Cheng, Yilong ^a,b   He, Chaoliang ^a   Ding, Jianxun ^a   Xiao, Chunsheng ^a   Zhuang, Xiuli ^a   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Anticancer; Local chemotherapy; Paclitaxel; Polypeptide; Thermosensitive hydrogels

Indexed keywords

ANTI-CANCER DRUG DELIVERY; ANTI-TUMORAL ACTIVITY; ANTICANCER; ANTICANCER DRUG; ANTITUMOR DRUGS; GELATION CONCENTRATIONS; PACLITAXEL; THERMO-SENSITIVE HYDROGEL;

BIOCOMPATIBILITY; CHEMOTHERAPY; DRUG DELIVERY; GELATION; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYPEPTIDES;

HYDROGELS;

COPOLYMER; MACROGOL; PACLITAXEL; POLY(GAMMA ETHYL L GLUTAMATE); POLYPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; GELATION; HEAT SENSITIVITY; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SUSTAINED DRUG RELEASE; TUMOR GROWTH;

ANTICANCER; LOCAL CHEMOTHERAPY; PACLITAXEL; POLYPEPTIDE; THERMOSENSITIVE HYDROGELS;

ANIMALS; ANTINEOPLASTIC AGENTS; FEMALE; HYDROGELS; IN SITU NICK-END LABELING; MICE, NUDE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84885385174     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.064     Document Type: Article

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