Efflux transporter engineering markedly improves amorphadiene production in Escherichia coli

Biotechnology and Bioengineering

Volumn 113, Issue 8, 2016, Pages 1755-1763

  Zhang, Congqiang ^a,b   Chen, Xixian ^a,b   Stephanopoulos, Gregory ^a,c   Too, Heng Phon ^a,b,d  

^a SINGAPORE MIT ALLIANCE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c Massachusetts Institute of Technology   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

amorphadiene; artemisinin; efflux pump; lipopolysaccharide transport system; TolC; transporter engineering

Indexed keywords

BIOLOGICAL MEMBRANES; ESCHERICHIA COLI; METABOLISM; SUBSTRATES; TRANSPORTATION;

AMORPHADIENE; ARTEMISININ; EFFLUX PUMPS; TOLC; TRANSPORT SYSTEMS;

METABOLIC ENGINEERING;

ABC TRANSPORTER; DODECANE; EMRAB PROTEIN; EMRKY PROTEIN; LIPOPOLYSACCHARIDE; LPTCABFG PROTEIN; LPTD PROTEIN; MSBA PROTEIN; OUTER MEMBRANE PROTEIN; TOLC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CELL DENSITY; CELL GROWTH; EFFLUX TRANSPORTER ENGINEERING; ESCHERICHIA COLI; GENE DELETION; GENE INACTIVATION; GENE OVEREXPRESSION; HYDROPHOBICITY; INNER MEMBRANE; METABOLIC ENGINEERING; NONHUMAN; WILD TYPE;

EID: 84977111493     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25943     Document Type: Article

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