Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: Role of acid sphingomyelinase gene

Oncotarget

Volumn 7, Issue 14, 2016, Pages 19031-19044

  Boini, Krishna M ^a   Xia, Min ^a   Koka, Saisudha ^a   Gehr, Todd W ^a   Li, Pin Lan ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Ceramide; End stage renal disease; Glomerulosclerosis; Inflammasomes; Obesity

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; CERAMIDE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PEPTIDES AND PROTEINS; PODOCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SHORT HAIRPIN RNA; SPHINGOMYELIN PHOSPHODIESTERASE; SUPEROXIDE; UNCLASSIFIED DRUG; NLRP3 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASM GENE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLUORESCENCE ANALYSIS; GENE ACTIVITY; GENE SILENCING; GLOMERULOSCLEROSIS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY INJURY; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN LOCALIZATION; PROTEINURIA; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; GLOMERULONEPHRITIS; IMMUNOLOGY; KNOCKOUT MOUSE; LIPID DIET; METABOLISM;

ANIMALS; CERAMIDES; DIET, HIGH-FAT; GENE SILENCING; GLOMERULONEPHRITIS; INFLAMMASOMES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; RNA, SMALL INTERFERING; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSFECTION;

EID: 84975453069     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8023     Document Type: Article

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