STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation

FASEB Journal

Volumn 30, Issue 1, 2016, Pages 129-140

  Pedroza, Mesias ^a   Le, Thuy T ^b   Lewis, Katherine ^a   Karmouty Quintana, Harry ^b   To, Sarah ^a   George, Anuh T ^a   Blackburn, Michael R ^b   Tweardy, David J ^a   Agarwal, Sandeep K ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Epithelial injury; Fibrosis; Myofibroblast; STAT3

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; C 1889; COLLAGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN INHIBITOR; SMAD2 PROTEIN; SMAD3 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; STAT3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL OXYGEN SATURATION; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FIBROSING ALVEOLITIS; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM CELL; LUNG BIOPSY; LUNG FIBROBLAST; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPIROMETRY; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; LUNG; METABOLISM; PHYSIOLOGY;

ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; IDIOPATHIC PULMONARY FIBROSIS; LUNG; MALE; MICE, INBRED C57BL; MYOFIBROBLASTS; STAT3 TRANSCRIPTION FACTOR;

EID: 84974779222     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-273953     Document Type: Article

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