Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 300, Issue 5, 2011, Pages

  Ueno, Manabu ^a   Maeno, Toshitaka ^a   Nomura, Miyuki ^a   Aoyagi Ikeda, Kana ^a   Matsui, Hiroki ^a   Hara, Kenichiro ^a   Tanaka, Toru ^a   Iso, Tatsuya ^a   Suga, Tatsuo ^a   Kurabayashi, Masahiko ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hypoxia inducible factor 1 ; Plasminogen activator inhibitor 1; Pulmonary fibrosis; Transforming growth factor

Indexed keywords

BLEOMYCIN; COMPLEMENTARY DNA; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET DERIVED GROWTH FACTOR A; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONTROL; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; BENZAMIDES; BLEOMYCIN; CELL HYPOXIA; DIOXOLES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 79955784909     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00146.2010     Document Type: Article

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