Internal guide RNA interactions interfere with Cas9-mediated cleavage

Nature Communications

Volumn 7, Issue , 2016, Pages

  Thyme, Summer B ^a   Akhmetova, Laila ^a   Montague, Tessa G ^a   Valen, Eivind ^b   Schier, Alexander F ^a,c,d  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF BERGEN   (Norway)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; GUIDE RNA; TRANSCRIPTION FACTOR CTCF; CRISPR ASSOCIATED PROTEIN;

COMPLEXITY; CYPRINID; EMBRYO; EMBRYONIC DEVELOPMENT; ENZYME ACTIVITY; GENE EXPRESSION; MUTAGENICITY; RNA;

ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENOMICS; IN VITRO STUDY; IN VIVO STUDY; INTERACTIONS WITH RNA; MUTAGENESIS; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN RNA BINDING; RNA SEQUENCE; RNA STRUCTURE; ZEBRA FISH; ANIMAL; CHEMISTRY; CONFORMATION; GENOME; METABOLISM; NUCLEOTIDE SEQUENCE;

DANIO RERIO;

ANIMALS; BASE SEQUENCE; CRISPR-ASSOCIATED PROTEINS; GENOME; NUCLEIC ACID CONFORMATION; RNA, GUIDE; ZEBRAFISH;

EID: 84974644123     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11750     Document Type: Article

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