-
1
-
-
2442424380
-
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
-
Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA (2004) Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 61, 661-666.
-
(2004)
Arch Neurol
, vol.61
, pp. 661-666
-
-
Arvanitakis, Z.1
Wilson, R.S.2
Bienias, J.L.3
Evans, D.A.4
Bennett, D.A.5
-
2
-
-
84861450111
-
Diabetes as a risk factor for dementia and mild cognitive impairment: A meta-analysis of longitudinal studies
-
Cheng G, Huang C, Deng H, Wang H (2012) Diabetes as a risk factor for dementia and mild cognitive impairment: A meta-analysis of longitudinal studies. Intern Med J 42, 484-491.
-
(2012)
Intern Med J
, vol.42
, pp. 484-491
-
-
Cheng, G.1
Huang, C.2
Deng, H.3
Wang, H.4
-
3
-
-
84928116660
-
Link between type 2 diabetes and Alzheimer's disease: From epidemiology to mechanism and treatment
-
Li X, Song D, Leng SX (2015) Link between type 2 diabetes and Alzheimer's disease: From epidemiology to mechanism and treatment. Clin Interv Aging 10, 549-560.
-
(2015)
Clin Interv Aging
, vol.10
, pp. 549-560
-
-
Li, X.1
Song, D.2
Leng, S.X.3
-
4
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A, Stolk RP, van Harskamp F, Pols HA, Hofman A, Breteler MM (1999) Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 53, 1937-1942.
-
(1999)
Neurology
, vol.53
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
Van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
5
-
-
0036227542
-
Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies
-
Peila R, Rodriguez BL, Launer LJ (2002) Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies. Diabetes 51, 1256-1262.
-
(2002)
Diabetes
, vol.51
, pp. 1256-1262
-
-
Peila, R.1
Rodriguez, B.L.2
Launer, L.J.3
-
6
-
-
78650029989
-
Insulin metabolism and the risk of Alzheimer disease the Rotterdam Study
-
Schrijvers EMC, Witteman JCM, Sijbrands EJG, Hofman A, Koudstaal PJ, Breteler MMB (2010) Insulin metabolism and the risk of Alzheimer disease The Rotterdam Study. Neurology 75, 1982-1987.
-
(2010)
Neurology
, vol.75
, pp. 1982-1987
-
-
Schrijvers, E.M.C.1
Witteman, J.C.M.2
Sijbrands, E.J.G.3
Hofman, A.4
Koudstaal, P.J.5
Breteler, M.M.B.6
-
7
-
-
84968822322
-
-
International Diabetes, Federation, 6th edition, International Diabetes Federation, Brussels
-
International Diabetes, Federation (2014) IDF Diabetes Atlas, 6th edition, International Diabetes Federation, Brussels.
-
(2014)
IDF Diabetes Atlas
-
-
-
8
-
-
15244350991
-
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
-
de la Monte SM, Wands J (2005) Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease. J Alzheimers Dis 7, 45-61.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 45-61
-
-
De La Monte, S.M.1
Wands, J.2
-
9
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Group DPPR
-
Knowler WC, Barrett-Conner E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM, Group DPPR (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346, 393-403.
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Conner, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
10
-
-
84944714835
-
Hippocampal insulin resistance and cognitive dysfunction
-
Biessels GJ, Reagan LP (2015) Hippocampal insulin resistance and cognitive dysfunction. Nat Rev Neurosci 16, 660-671.
-
(2015)
Nat Rev Neurosci
, vol.16
, pp. 660-671
-
-
Biessels, G.J.1
Reagan, L.P.2
-
11
-
-
84947614766
-
Impaired insulin action in the human brain: Causes and metabolic consequences
-
Heni M, Kullmann S, Preissl H, Fritsche A, Haring HU (2015) Impaired insulin action in the human brain: Causes and metabolic consequences. Nat Rev Endocrinol 11, 701-711.
-
(2015)
Nat Rev Endocrinol
, vol.11
, pp. 701-711
-
-
Heni, M.1
Kullmann, S.2
Preissl, H.3
Fritsche, A.4
Haring, H.U.5
-
12
-
-
1242316296
-
Insulin and neurodegenerative disease: Shared and specific mechanisms
-
Craft S, Watson GS (2004) Insulin and neurodegenerative disease: Shared and specific mechanisms. Lancet Neurol 3, 169-178.
-
(2004)
Lancet Neurol
, vol.3
, pp. 169-178
-
-
Craft, S.1
Watson, G.S.2
-
13
-
-
0029163166
-
Desensitization of the neuronal insulin receptor: A new approach in the etiopathogenesis of late-onset sporadic dementia of the Alzheimer type (SDAT)?
-
Henneberg N, Hoyer S (1995) Desensitization of the neuronal insulin receptor: A new approach in the etiopathogenesis of late-onset sporadic dementia of the Alzheimer type (SDAT)? Arch Gerontol Geriatr 21, 63-74.
-
(1995)
Arch Gerontol Geriatr
, vol.21
, pp. 63-74
-
-
Henneberg, N.1
Hoyer, S.2
-
14
-
-
1842633872
-
Insulin and the insulin receptor in experimental models of learning and memory
-
Zhao WQ, Chen H, Quon MJ, Alkon DL (2004) Insulin and the insulin receptor in experimental models of learning and memory. Eur J Pharmacol 490, 71-81.
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 71-81
-
-
Zhao, W.Q.1
Chen, H.2
Quon, M.J.3
Alkon, D.L.4
-
15
-
-
78651274000
-
Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
-
Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, Craft S (2011) Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 68, 51-57.
-
(2011)
Arch Neurol
, vol.68
, pp. 51-57
-
-
Baker, L.D.1
Cross, D.J.2
Minoshima, S.3
Belongia, D.4
Watson, G.S.5
Craft, S.6
-
16
-
-
33747058235
-
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans:Amagnetoencephalographic study
-
Tschritter O, Preissl H, Hennige AM, Stumvoll M, Porubska K, Frost R, Marx H, Klosel B, Lutzenberger W, Birbaumer N, Haring HU, Fritsche A (2006) The cerebrocortical response to hyperinsulinemia is reduced in overweight humans:Amagnetoencephalographic study. Proc Natl Acad Sci U S A 103, 12103-12108.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12103-12108
-
-
Tschritter, O.1
Preissl, H.2
Hennige, A.M.3
Stumvoll, M.4
Porubska, K.5
Frost, R.6
Marx, H.7
Klosel, B.8
Lutzenberger, W.9
Birbaumer, N.10
Haring, H.U.11
Fritsche, A.12
-
17
-
-
0037452760
-
Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly
-
Convit A, WolfOT, Tarshish C, de Leon MJ (2003) Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly. Proc Natl Acad Sci U S A 100, 2019-2022.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2019-2022
-
-
Convit, A.1
Wolf, O.T.2
Tarshish, C.3
De Leon, M.J.4
-
18
-
-
84873817577
-
Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults
-
Willette AA, Xu G, Johnson SC, Birdsill AC, Jonaitis EM, Sager MA, Hermann BP, La Rue A, Asthana S, Bendlin BB (2013) Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 36, 443-449.
-
(2013)
Diabetes Care
, vol.36
, pp. 443-449
-
-
Willette, A.A.1
Xu, G.2
Johnson, S.C.3
Birdsill, A.C.4
Jonaitis, E.M.5
Sager, M.A.6
Hermann, B.P.7
La Rue, A.8
Asthana, S.9
Bendlin, B.B.10
-
19
-
-
84942247845
-
Association of insulin resistance with cerebral glucose uptake in late middle-aged adults at risk for Alzheimer disease
-
Willette AA, Bendlin BB, Starks EJ, Birdsill AC, Johnson SC, Christian BT, Okonkwo OC, La Rue A, Hermann BP, Koscik RL, Jonaitis EM, Sager MA, Asthana S (2015) Association of insulin resistance with cerebral glucose uptake in late middle-aged adults at risk for Alzheimer disease. JAMA Neurol 72, 1013-1020.
-
(2015)
JAMA Neurol
, vol.72
, pp. 1013-1020
-
-
Willette, A.A.1
Bendlin, B.B.2
Starks, E.J.3
Birdsill, A.C.4
Johnson, S.C.5
Christian, B.T.6
Okonkwo, O.C.7
La Rue, A.8
Hermann, B.P.9
Koscik, R.L.10
Jonaitis, E.M.11
Sager, M.A.12
Asthana, S.13
-
20
-
-
77956364857
-
Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study
-
Matsuzaki T, Sasaki K, TanizakiY, Hata J, Fujimi K, Matsui Y, Sekita A, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T (2010) Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study. Neurology 75, 764-770.
-
(2010)
Neurology
, vol.75
, pp. 764-770
-
-
Matsuzaki, T.1
Sasaki, K.2
Tanizaki, Y.3
Hata, J.4
Fujimi, K.5
Matsui, Y.6
Sekita, A.7
Suzuki, S.O.8
Kanba, S.9
Kiyohara, Y.10
Iwaki, T.11
-
21
-
-
84948978519
-
Type 2 diabetes mellitus and biomarkers of neurodegeneration
-
Alzheimer's Disease Neuroimaging Initiative (ADNI)
-
Moran C, Beare R, Phan TG, Bruce DG, Callisaya ML, Srikanth V, Alzheimer's Disease Neuroimaging Initiative (ADNI) (2015). Type 2 diabetes mellitus and biomarkers of neurodegeneration. Neurology 85, 1123-1130.
-
(2015)
Neurology
, vol.85
, pp. 1123-1130
-
-
Moran, C.1
Beare, R.2
Phan, T.G.3
Bruce, D.G.4
Callisaya, M.L.5
Srikanth, V.6
-
22
-
-
33845704496
-
Diabetes is related to cerebral infarction but not to AD pathology in older persons
-
Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA (2006) Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology 67, 1960-1965.
-
(2006)
Neurology
, vol.67
, pp. 1960-1965
-
-
Arvanitakis, Z.1
Schneider, J.A.2
Wilson, R.S.3
Li, Y.4
Arnold, S.E.5
Wang, Z.6
Bennett, D.A.7
-
23
-
-
21044455285
-
Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology
-
Beeri MS, Silverman JM, Davis KL, Marin D, Grossman HZ, Schmeidler J, Purohit DP, Perl DP, Davidson M, Mohs RC, Haroutunian V (2005) Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology. J Gerontol A Biol Sci Med Sci 60, 471-475.
-
(2005)
J Gerontol A Biol Sci Med Sci
, vol.60
, pp. 471-475
-
-
Beeri, M.S.1
Silverman, J.M.2
Davis, K.L.3
Marin, D.4
Grossman, H.Z.5
Schmeidler, J.6
Purohit, D.P.7
Perl, D.P.8
Davidson, M.9
Mohs, R.C.10
Haroutunian, V.11
-
24
-
-
84901299033
-
Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation
-
Roberts RO, Knopman DS, Cha RH, Mielke MM, Pankratz VS, Boeve BF, Kantarci K, Geda YE, Jack CR Jr, Petersen RC, Lowe VJ (2014) Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation. J Nucl Med 55, 759-764.
-
(2014)
J Nucl Med
, vol.55
, pp. 759-764
-
-
Roberts, R.O.1
Knopman, D.S.2
Cha, R.H.3
Mielke, M.M.4
Pankratz, V.S.5
Boeve, B.F.6
Kantarci, K.7
Geda, Y.E.8
Jack, C.R.9
Petersen, R.C.10
Lowe, V.J.11
-
25
-
-
84883824146
-
Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging
-
Thambisetty M, JeffreyMetter E, Yang A, Dolan H, Marano C, Zonderman AB, Troncoso JC, Zhou Y, Wong DF, Ferrucci L, Egan J, Resnick SM, O'Brien RJ (2013) Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging. JAMA Neurol 70, 1167-1172.
-
(2013)
JAMA Neurol
, vol.70
, pp. 1167-1172
-
-
Thambisetty, M.1
JeffreyMetter, E.2
Yang, A.3
Dolan, H.4
Marano, C.5
Zonderman, A.B.6
Troncoso, J.C.7
Zhou, Y.8
Wong, D.F.9
Ferrucci, L.10
Egan, J.11
Resnick, S.M.12
O'Brien, R.J.13
-
26
-
-
84929295476
-
Insulin resistance predicts brain amyloid deposition in late middle-aged adults
-
Willette AA, Johnson SC, Birdsill AC, Sager MA, Christian B, Baker LD, Craft S, Oh J, Statz E, Hermann BP, Jonaitis EM, Koscik RL, La Rue A, Asthana S, Bendlin BB (2015) Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimers Dement 11, 504-510 e501.
-
(2015)
Alzheimers Dement
, vol.11
, pp. 504e501-510e501
-
-
Willette, A.A.1
Johnson, S.C.2
Birdsill, A.C.3
Sager, M.A.4
Christian, B.5
Baker, L.D.6
Craft, S.7
Oh, J.8
Statz, E.9
Hermann, B.P.10
Jonaitis, E.M.11
Koscik, R.L.12
La Rue, A.13
Asthana, S.14
Bendlin, B.B.15
-
27
-
-
0034644836
-
Regulation of APP cleavage by alpha-, beta-and gamma-secretases
-
Nunan J, Small DH (2000) Regulation of APP cleavage by alpha-, beta-and gamma-secretases. FEBS Lett 483, 6-10.
-
(2000)
FEBS Lett
, vol.483
, pp. 6-10
-
-
Nunan, J.1
Small, D.H.2
-
28
-
-
84878946078
-
The amyloid precursor protein: A biochemical enigma in brain development, function and disease
-
Nalivaeva NN, Turner AJ (2013) The amyloid precursor protein: A biochemical enigma in brain development, function and disease. FEBS Lett 587, 2046-2054.
-
(2013)
FEBS Lett
, vol.587
, pp. 2046-2054
-
-
Nalivaeva, N.N.1
Turner, A.J.2
-
29
-
-
84923250107
-
Cellular functions of the amyloid precursor protein from development to dementia
-
van der Kant R, Goldstein LS (2015) Cellular functions of the amyloid precursor protein from development to dementia. Dev Cell 32, 502-515.
-
(2015)
Dev Cell
, vol.32
, pp. 502-515
-
-
Van Der Kant, R.1
Goldstein, L.S.2
-
30
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL (2004) Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci 24, 10191-10200.
-
(2004)
J Neurosci
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
31
-
-
33846633336
-
Abeta oligomerinduced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
-
Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL (2007) Abeta oligomerinduced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 27, 796-807.
-
(2007)
J Neurosci
, vol.27
, pp. 796-807
-
-
Lacor, P.N.1
Buniel, M.C.2
Furlow, P.W.3
Clemente, A.S.4
Velasco, P.T.5
Wood, M.6
Viola, K.L.7
Klein, W.L.8
-
32
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from A-1-42 are potent central nervous system neurotoxins
-
Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL (1998) Diffusible, nonfibrillar ligands derived from A-1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A 96, 6448-6453.
-
(1998)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
33
-
-
0037884977
-
Synaptic plasticity in animal models of early Alzheimer's disease
-
Rowan MJ, Klyubin I, Cullen WK, Anwyl R (2003) Synaptic plasticity in animal models of early Alzheimer's disease. Philos Trans R Soc Lond B Biol Sci 358, 821-828.
-
(2003)
Philos Trans R Soc Lond B Biol Sci
, vol.358
, pp. 821-828
-
-
Rowan, M.J.1
Klyubin, I.2
Cullen, W.K.3
Anwyl, R.4
-
34
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14, 837-842.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
35
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
FarrisW, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S (2003) Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci U S A 100, 4162-4167.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
Frosch, M.P.6
Eckman, C.B.7
Tanzi, R.E.8
Selkoe, D.J.9
Guenette, S.10
-
36
-
-
0035871641
-
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling
-
Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H (2001) Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci 21, 2561-2570.
-
(2001)
J Neurosci
, vol.21
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
Xu, H.7
-
37
-
-
4644286910
-
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
-
Ho L, QinW, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM (2004) Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J 18, 902-904.
-
(2004)
FASEB J
, vol.18
, pp. 902-904
-
-
Ho, L.1
Qin, W.2
Pompl, P.N.3
Xiang, Z.4
Wang, J.5
Zhao, Z.6
Peng, Y.7
Cambareri, G.8
Rocher, A.9
Mobbs, C.V.10
Hof, P.R.11
Pasinetti, G.M.12
-
38
-
-
0347719366
-
Functional brain abnormalities in young adults at genetic risk for lateonset Alzheimer's dementia
-
Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Osborne D, Saunders AM, Hardy J (2004) Functional brain abnormalities in young adults at genetic risk for lateonset Alzheimer's dementia. Proc Natl Acad Sci U S A 101, 284-289.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 284-289
-
-
Reiman, E.M.1
Chen, K.2
Alexander, G.E.3
Caselli, R.J.4
Bandy, D.5
Osborne, D.6
Saunders, A.M.7
Hardy, J.8
-
39
-
-
20444395466
-
Correlations between apolipoprotein e epsilon4 gene dose and brainimaging measurements of regional hypometabolism
-
Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Osborne D, Saunders AM, Hardy J (2005) Correlations between apolipoprotein E epsilon4 gene dose and brainimaging measurements of regional hypometabolism. Proc Natl Acad Sci U S A 102, 8299-8302.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8299-8302
-
-
Reiman, E.M.1
Chen, K.2
Alexander, G.E.3
Caselli, R.J.4
Bandy, D.5
Osborne, D.6
Saunders, A.M.7
Hardy, J.8
-
40
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, WuHM, Mega MS, Cummings JL, SaundersAM, Pericak-VanceMA, Roses AD, Barrio JR, PhelpsME(2000) Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 97, 6037-6042.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
Bookheimer, S.Y.6
Lavretsky, H.7
Miller, K.8
Siddarth, P.9
Rasgon, N.L.10
Mazziotta, J.C.11
Saxena, S.12
Wu, H.M.13
Mega, M.S.14
Cummings, J.L.15
Saunders, A.M.16
Pericak-Vance, M.A.17
Roses, A.D.18
Barrio, J.R.19
Phelps, M.E.20
more..
-
41
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E, Saunders A, StrittmatterW, Schmechel D, Gaskell P, Small G, Roses A, Haines J, Pericak-Vance M (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.1
Saunders, A.2
Strittmatter, W.3
Schmechel, D.4
Gaskell, P.5
Small, G.6
Roses, A.7
Haines, J.8
Pericak-Vance, M.9
-
42
-
-
12844285146
-
No epsilon4 gene dose effect on hippocampal atrophy in a large MRI database of healthy elderly subjects
-
Lemaitre H, Crivello F, Dufouil C, Grassiot B, Tzourio C, Alperovitch A, Mazoyer B (2005) No epsilon4 gene dose effect on hippocampal atrophy in a large MRI database of healthy elderly subjects. Neuroimage 24, 1205-1213.
-
(2005)
Neuroimage
, vol.24
, pp. 1205-1213
-
-
Lemaitre, H.1
Crivello, F.2
Dufouil, C.3
Grassiot, B.4
Tzourio, C.5
Alperovitch, A.6
Mazoyer, B.7
-
43
-
-
84896855511
-
Hippocampus-related cognitive impairments in young apoE4 targeted replacement mice
-
Salomon-Zimri S, Boehm-Cagan A, Liraz O, Michaelson DM (2014) Hippocampus-related cognitive impairments in young apoE4 targeted replacement mice. Neurodegener Dis 13, 86-92.
-
(2014)
Neurodegener Dis
, vol.13
, pp. 86-92
-
-
Salomon-Zimri, S.1
Boehm-Cagan, A.2
Liraz, O.3
Michaelson, D.M.4
-
44
-
-
33645808672
-
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
-
Mahley RW, Weisgraber KH, Huang Y (2006) Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc Natl Acad Sci U S A 103, 5644-5651.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5644-5651
-
-
Mahley, R.W.1
Weisgraber, K.H.2
Huang, Y.3
-
45
-
-
77955350021
-
ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling
-
Chen Y, Durakoglugil MS, Xian X, Herz J (2010) ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling. Proc Natl Acad Sci U S A 107, 12011-12016.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12011-12016
-
-
Chen, Y.1
Durakoglugil, M.S.2
Xian, X.3
Herz, J.4
-
46
-
-
84899687398
-
White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease
-
Adluru N, Destiche DJ, Lu SY, Doran ST, Birdsill AC, Melah KE, Okonkwo OC, Alexander AL, Dowling NM, Johnson SC, Sager MA, Bendlin BB (2014) White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease. Neuroimage Clin 4, 730-742.
-
(2014)
Neuroimage Clin
, vol.4
, pp. 730-742
-
-
Adluru, N.1
Destiche, D.J.2
Lu, S.Y.3
Doran, S.T.4
Birdsill, A.C.5
Melah, K.E.6
Okonkwo, O.C.7
Alexander, A.L.8
Dowling, N.M.9
Johnson, S.C.10
Sager, M.A.11
Bendlin, B.B.12
-
47
-
-
75649117447
-
Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease
-
Honea RA, SwerdlowRH, Vidoni ED, Goodwin J, BurnsJM (2010) Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease. Neurology 74, 113-120.
-
(2010)
Neurology
, vol.74
, pp. 113-120
-
-
Honea, R.A.1
Swerdlow, R.H.2
Vidoni, E.D.3
Goodwin, J.4
Burns, J.M.5
-
48
-
-
79952381749
-
Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease
-
Honea RA, Swerdlow RH, Vidoni ED, Burns JM (2011) Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease. Neurology 76, 822-829.
-
(2011)
Neurology
, vol.76
, pp. 822-829
-
-
Honea, R.A.1
Swerdlow, R.H.2
Vidoni, E.D.3
Burns, J.M.4
-
49
-
-
33745248702
-
The influence of Alzheimer disease family history and apolipoprotein e epsilon4 on mesial temporal lobe activation
-
Johnson SC, Schmitz TW, Trivedi MA, Ries ML, Torgerson BM, Carlsson CM, Asthana S, Hermann BP, Sager MA (2006) The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. J Neurosci 26, 6069-6076.
-
(2006)
J Neurosci
, vol.26
, pp. 6069-6076
-
-
Johnson, S.C.1
Schmitz, T.W.2
Trivedi, M.A.3
Ries, M.L.4
Torgerson, B.M.5
Carlsson, C.M.6
Asthana, S.7
Hermann, B.P.8
Sager, M.A.9
-
50
-
-
84889589925
-
Amyloid burden and neural function in people at risk for Alzheimer's disease
-
Johnson SC, Christian BT, Okonkwo OC, Oh JM, Harding S, Xu G, Hillmer AT, Wooten DW, Murali D, Barnhart TE, Hall LT, Racine AM, Klunk WE, Mathis CA, Bendlin BB, Gallagher CL, Carlsson CM, Rowley HA, Hermann BP, Dowling NM, Asthana S, Sager MA (2014) Amyloid burden and neural function in people at risk for Alzheimer's disease. Neurobiol Aging 35, 576-584.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 576-584
-
-
Johnson, S.C.1
Christian, B.T.2
Okonkwo, O.C.3
Oh, J.M.4
Harding, S.5
Xu, G.6
Hillmer, A.T.7
Wooten, D.W.8
Murali, D.9
Barnhart, T.E.10
Hall, L.T.11
Racine, A.M.12
Klunk, W.E.13
Mathis, C.A.14
Bendlin, B.B.15
Gallagher, C.L.16
Carlsson, C.M.17
Rowley, H.A.18
Hermann, B.P.19
Dowling, N.M.20
Asthana, S.21
Sager, M.A.22
more..
-
51
-
-
77950546575
-
Increased fibrillar amyloid-beta burden in normal individuals with a family history of late-onset Alzheimer's
-
Mosconi L, Rinne JO, Tsui WH, Berti V, Li Y, Wang H, Murray J, Scheinin N, Nagren K, Williams S, Glodzik L, De Santi S, Vallabhajosula S, de Leon MJ (2010) Increased fibrillar amyloid-beta burden in normal individuals with a family history of late-onset Alzheimer's. Proc Natl Acad Sci U S A 107, 5949-5954.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5949-5954
-
-
Mosconi, L.1
Rinne, J.O.2
Tsui, W.H.3
Berti, V.4
Li, Y.5
Wang, H.6
Murray, J.7
Scheinin, N.8
Nagren, K.9
Williams, S.10
Glodzik, L.11
De Santi, S.12
Vallabhajosula, S.13
De Leon, M.J.14
-
52
-
-
84863611781
-
Family history of Alizheimer disease predicts hippocampal atrophy in healthy middle-aged adults
-
Okonkwo OC, Xu G, Dowling NM, Bendlin BB, LaRue A, Hermann BP, Koscik R, Jonaitis E, Rowley HA, Carlsson CM, Asthana S, Sager MA, Johnson SC (2012) Family history of Alizheimer disease predicts hippocampal atrophy in healthy middle-aged adults. Neurology 78, 1769-1776.
-
(2012)
Neurology
, vol.78
, pp. 1769-1776
-
-
Okonkwo, O.C.1
Xu, G.2
Dowling, N.M.3
Bendlin, B.B.4
LaRue, A.5
Hermann, B.P.6
Koscik, R.7
Jonaitis, E.8
Rowley, H.A.9
Carlsson, C.M.10
Asthana, S.11
Sager, M.A.12
Johnson, S.C.13
-
53
-
-
3442877311
-
Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: The REVEAL study
-
Cupples LA, Farrer LA, Sadovnick AD, Relkin N, Whitehouse P, Green RC (2004) Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: The REVEAL study. Genet Med 6, 192-196.
-
(2004)
Genet Med
, vol.6
, pp. 192-196
-
-
Cupples, L.A.1
Farrer, L.A.2
Sadovnick, A.D.3
Relkin, N.4
Whitehouse, P.5
Green, R.C.6
-
54
-
-
84907863957
-
Three midlife strategies to prevent cognitive impairment due to Alzheimer's disease
-
Henderson VW (2014) Three midlife strategies to prevent cognitive impairment due to Alzheimer's disease. Climacteric 17, 38-46.
-
(2014)
Climacteric
, vol.17
, pp. 38-46
-
-
Henderson, V.W.1
-
55
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group1 under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann GM, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group1 under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.M.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
56
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH (2011) The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
Hyman, B.T.4
Jack, C.R.5
Kawas, C.H.6
Klunk, W.E.7
Koroshetz, W.J.8
Manly, J.J.9
Mayeux, R.10
Mohs, R.C.11
Morris, J.C.12
Rossor, M.N.13
Scheltens, P.14
Carrillo, M.C.15
Thies, B.16
Weintraub, S.17
Phelps, C.H.18
-
57
-
-
0028024912
-
A validation study of the Dementia Questionnaire
-
Kawas CH, Segal J, StewartWF, Corrada M, Thal LJ (1994) A validation study of the Dementia Questionnaire. Arch Neurol 51, 901-906.
-
(1994)
Arch Neurol
, vol.51
, pp. 901-906
-
-
Kawas, C.H.1
Segal, J.2
Stewart, W.F.3
Corrada, M.4
Thal, L.J.5
-
58
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
59
-
-
84907978955
-
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: A cross-validation study against amyloid positron emission tomography
-
Palmqvist S, Zetterberg H, Blennow K, Vestberg S, Andreasson U, Brooks DJ, Owenius R, Hagerstrom D, Wollmer P, Minthon L, HanssonO(2014) Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: A cross-validation study against amyloid positron emission tomography. JAMA Neurol 71, 1282-1289.
-
(2014)
JAMA Neurol
, vol.71
, pp. 1282-1289
-
-
Palmqvist, S.1
Zetterberg, H.2
Blennow, K.3
Vestberg, S.4
Andreasson, U.5
Brooks, D.J.6
Owenius, R.7
Hagerstrom, D.8
Wollmer, P.9
Minthon, L.10
Hansson, O.11
-
61
-
-
0345392666
-
Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer's disease: Comparison with mild cognitive impairment and normal aging
-
Estevez-Gonzalez A, Kulisevsky J, Boltes A, Otermin P, Garcia-Sanchez C (2003) Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer's disease: Comparison with mild cognitive impairment and normal aging. Int J Geriatr Psychiatry 18, 1021-1028.
-
(2003)
Int J Geriatr Psychiatry
, vol.18
, pp. 1021-1028
-
-
Estevez-Gonzalez, A.1
Kulisevsky, J.2
Boltes, A.3
Otermin, P.4
Garcia-Sanchez, C.5
-
62
-
-
84861198255
-
Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance
-
North American Alzheimer's Disease Neuroimaging Initiative
-
Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Petersen RC, Jack CR Jr, Feldman HH, Bokde AL, Alexander GE, Scheltens P, Vellas B, Dubois B, Weiner M, Hampel H, North American Alzheimer's Disease Neuroimaging Initiative (2012) Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance. Neurobiol Aging 33, 1203-1214.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1203-1214
-
-
Ewers, M.1
Walsh, C.2
Trojanowski, J.Q.3
Shaw, L.M.4
Petersen, R.C.5
Jack, C.R.6
Feldman, H.H.7
Bokde, A.L.8
Alexander, G.E.9
Scheltens, P.10
Vellas, B.11
Dubois, B.12
Weiner, M.13
Hampel, H.14
-
63
-
-
84857714157
-
Mechanisms underlying insulin deficiency-induced acceleration of beta-amyloidosis in a mouse model of Alzheimer's disease
-
Devi L, Alldred MJ, Ginsberg SD, Ohno M (2012) Mechanisms underlying insulin deficiency-induced acceleration of beta-amyloidosis in a mouse model of Alzheimer's disease. PLoS One 7, e32792.
-
(2012)
PLoS One
, vol.7
, pp. e32792
-
-
Devi, L.1
Alldred, M.J.2
Ginsberg, S.D.3
Ohno, M.4
-
64
-
-
4644286910
-
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
-
Ho L, QinW, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM (2004) Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J 18, 902-904.
-
(2004)
FASEB J
, vol.18
, pp. 902-904
-
-
Ho, L.1
Qin, W.2
Pompl, P.N.3
Xiang, Z.4
Wang, J.5
Zhao, Z.6
Peng, Y.7
Cambareri, G.8
Rocher, A.9
Mobbs, C.V.10
Hof, P.R.11
Pasinetti, G.M.12
-
65
-
-
67650544970
-
Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}
-
ZhaoWQ, Lacor PN, Chen H, LambertMP, Quon MJ, Krafft GA, Klein WL (2009) Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. J Biol Chem 284, 18742-18753.
-
(2009)
J Biol Chem
, vol.284
, pp. 18742-18753
-
-
Zhao, W.Q.1
Lacor, P.N.2
Chen, H.3
Lambert, M.P.4
Quon, M.J.5
Krafft, G.A.6
Klein, W.L.7
-
66
-
-
0029128232
-
LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation
-
Kounnas MZ, Moir RD, Rebeck GW, Bush AL, Argraves WS, Tanzi RE, Hyman BT, Strickland DK (1995) LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell 82, 331-340.
-
(1995)
Cell
, vol.82
, pp. 331-340
-
-
Kounnas, M.Z.1
Moir, R.D.2
Rebeck, G.W.3
Bush, A.L.4
Argraves, W.S.5
Tanzi, R.E.6
Hyman, B.T.7
Strickland, D.K.8
-
67
-
-
0034016848
-
Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype
-
Craft S, Asthana S, Schellenberg G, Baker L, Cherrier M, Boyt AA, Martins RN, Raskind M, Perkind E, Plymate S (2000) Insulin effects on glucose metabolism, memory, and plasma amyloid precursor protein in Alzheimer's disease differ according to apolipoprotein-E genotype. Ann N Y Acad Sci 903, 222-228.
-
(2000)
Ann N y Acad Sci
, vol.903
, pp. 222-228
-
-
Craft, S.1
Asthana, S.2
Schellenberg, G.3
Baker, L.4
Cherrier, M.5
Boyt, A.A.6
Martins, R.N.7
Raskind, M.8
Perkind, E.9
Plymate, S.10
-
68
-
-
0037134505
-
Insulin-degrading enzyme rapidly removes the betaamyloid precursor protein intracellular domain (AICD)
-
Edbauer D, Willem M, Lammich S, Steiner H, Haass C (2002) Insulin-degrading enzyme rapidly removes the betaamyloid precursor protein intracellular domain (AICD). J Biol Chem 277, 13389-13393.
-
(2002)
J Biol Chem
, vol.277
, pp. 13389-13393
-
-
Edbauer, D.1
Willem, M.2
Lammich, S.3
Steiner, H.4
Haass, C.5
-
69
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: Review and hypothesis
-
Qiu WQ, Folstein MF (2006) Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: Review and hypothesis. Neurobiol Aging 27, 190-198.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
70
-
-
0027365822
-
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein e genotype in late-onset Alzheimer disease
-
Schmechel DE, Saunders AM, Strittmatter WJ, Crain BJ, Hulette CM, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD (1993) Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc Natl Acad Sci U S A 90, 9649-9653.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.J.4
Hulette, C.M.5
Joo, S.H.6
Pericak-Vance, M.A.7
Goldgaber, D.8
Roses, A.D.9
-
71
-
-
84859068426
-
Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly
-
Benedict C, Brooks SJ, Kullberg J, Burgos J, Kempton MJ, Nordenskjold R, Nylander R, Kilander L, Craft S, Larsson EM, Johansson L, Ahlstrom H, Lind L, Schioth HB (2012) Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly. Diabetes Care 35, 488-494.
-
(2012)
Diabetes Care
, vol.35
, pp. 488-494
-
-
Benedict, C.1
Brooks, S.J.2
Kullberg, J.3
Burgos, J.4
Kempton, M.J.5
Nordenskjold, R.6
Nylander, R.7
Kilander, L.8
Craft, S.9
Larsson, E.M.10
Johansson, L.11
Ahlstrom, H.12
Lind, L.13
Schioth, H.B.14
-
72
-
-
78650651998
-
Insulin resistance and hippocampal volume in women at risk for Alzheimer's disease
-
Rasgon NL, Kenna HA, Wroolie TE, Kelley R, Silverman D, Brooks J, Williams KE, Powers BN, Hallmayer J, Reiss A (2011) Insulin resistance and hippocampal volume in women at risk for Alzheimer's disease. Neurobiol Aging 32, 1942-1948.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1942-1948
-
-
Rasgon, N.L.1
Kenna, H.A.2
Wroolie, T.E.3
Kelley, R.4
Silverman, D.5
Brooks, J.6
Williams, K.E.7
Powers, B.N.8
Hallmayer, J.9
Reiss, A.10
-
73
-
-
55549139200
-
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
-
Stranahan AM, Norman ED, Lee K, Cutler RG, Telljohann RS, Egan JM, Mattson MP (2008) Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. Hippocampus 18, 1085-1088.
-
(2008)
Hippocampus
, vol.18
, pp. 1085-1088
-
-
Stranahan, A.M.1
Norman, E.D.2
Lee, K.3
Cutler, R.G.4
Telljohann, R.S.5
Egan, J.M.6
Mattson, M.P.7
-
74
-
-
0007234813
-
Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease
-
Convit A, de Asis J, de Leon MJ, Tarshish CY, De Santi S, Rusinek H (2000) Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease. Neurobiol Aging 21, 19-26.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 19-26
-
-
Convit, A.1
De Asis, J.2
De Leon, M.J.3
Tarshish, C.Y.4
De Santi, S.5
Rusinek, H.6
-
75
-
-
0034801730
-
Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
-
DuAT, SchuffN, Amend D, LaaksoMP, HsuYY, Jagust WJ, Yaffe K, Kramer JH, Reed B, Norman D, Chui HC, Weiner MW (2001) Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry 71, 441-447.
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.71
, pp. 441-447
-
-
Du, A.T.1
Schuff, N.2
Amend, D.3
Laakso, M.P.4
Hsu, Y.Y.5
Jagust, W.J.6
Yaffe, K.7
Kramer, J.H.8
Reed, B.9
Norman, D.10
Chui, H.C.11
Weiner, M.W.12
-
76
-
-
10744227105
-
Hippocampus and entorhinal cortex in mild cognitive impairment and early AD
-
Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hänninen T, Laakso MP, Hallikainen M, Vanhanen M, Nissinen A, Helkala E, Vainio P, Vanninen R, Partanen K, Soininen H (2004) Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiol Aging 25, 303-310.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 303-310
-
-
Pennanen, C.1
Kivipelto, M.2
Tuomainen, S.3
Hartikainen, P.4
Hänninen, T.5
Laakso, M.P.6
Hallikainen, M.7
Vanhanen, M.8
Nissinen, A.9
Helkala, E.10
Vainio, P.11
Vanninen, R.12
Partanen, K.13
Soininen, H.14
-
77
-
-
33646850082
-
Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI
-
Wang L, Zang Y, He Y, Liang M, Zhang X, Tian L, Wu T, Jiang T, Li K (2006) Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI. Neuroimage 31, 496-504.
-
(2006)
Neuroimage
, vol.31
, pp. 496-504
-
-
Wang, L.1
Zang, Y.2
He, Y.3
Liang, M.4
Zhang, X.5
Tian, L.6
Wu, T.7
Jiang, T.8
Li, K.9
-
78
-
-
75249106915
-
Insulin is a two-edged knife on the brain
-
Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI (2009) Insulin is a two-edged knife on the brain. J Alzheimers Dis 18, 483-507.
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 483-507
-
-
Cardoso, S.1
Correia, S.2
Santos, R.X.3
Carvalho, C.4
Santos, M.S.5
Oliveira, C.R.6
Perry, G.7
Smith, M.A.8
Zhu, X.9
Moreira, P.I.10
-
79
-
-
0035947044
-
Role of insulin and insulin receptor in learning and memory
-
Zhao WQ, Alkon DL (2001) Role of insulin and insulin receptor in learning and memory. Mol Cell Endocrinol 177, 125-134.
-
(2001)
Mol Cell Endocrinol
, vol.177
, pp. 125-134
-
-
Zhao, W.Q.1
Alkon, D.L.2
-
80
-
-
0031955618
-
Glucose, memory, and aging
-
Korol DL, Gold PE (1998) Glucose, memory, and aging. Am J Clin Nutr 67, 764S-771S.
-
(1998)
Am J Clin Nutr
, vol.67
, pp. 764S-771S
-
-
Korol, D.L.1
Gold, P.E.2
|