메뉴 건너뛰기




Volumn 11, Issue 5, 2015, Pages 504-510.e1

Insulin resistance predicts brain amyloid deposition in late middle-aged adults

Author keywords

Alzheimer's disease; Amyloid; Cognitively normal; Insulin resistance; PiB; Prefrontal

Indexed keywords

AMYLOID; PITTSBURGH COMPOUND B; 2-(4'-(METHYLAMINO)PHENYL)-6-HYDROXYBENZOTHIAZOLE; ANILINE DERIVATIVE; APOLIPOPROTEIN E; THIAZOLE DERIVATIVE;

EID: 84929295476     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2014.03.011     Document Type: Article
Times cited : (205)

References (40)
  • 1
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
    • S.M. de la Monte, and J.R. Wands Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease J Alzheimers Dis 7 2005 45 61
    • (2005) J Alzheimers Dis , vol.7 , pp. 45-61
    • De La Monte, S.M.1    Wands, J.R.2
  • 2
    • 82955245622 scopus 로고    scopus 로고
    • Consequences of aberrant insulin regulation in the brain: Can treating diabetes be effective for Alzheimer's disease
    • L. Arab, R. Sadeghi, D.G. Walker, L.F. Lue, and M.N. Sabbagh Consequences of aberrant insulin regulation in the brain: can treating diabetes be effective for Alzheimer's disease Curr Neuropharmacol 9 2011 693 705
    • (2011) Curr Neuropharmacol , vol.9 , pp. 693-705
    • Arab, L.1    Sadeghi, R.2    Walker, D.G.3    Lue, L.F.4    Sabbagh, M.N.5
  • 3
    • 0037390039 scopus 로고    scopus 로고
    • Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
    • W. Farris, S. Mansourian, Y. Chang, L. Lindsley, E.A. Eckman, and M.P. Frosch Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo Proc Natl Acad Sci U S A 100 2003 4162 4167
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4162-4167
    • Farris, W.1    Mansourian, S.2    Chang, Y.3    Lindsley, L.4    Eckman, E.A.5    Frosch, M.P.6
  • 4
    • 4644286910 scopus 로고    scopus 로고
    • Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
    • L. Ho, W. Qin, P.N. Pompl, Z. Xiang, J. Wang, and Z. Zhao Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease Faseb J 18 2004 902 904
    • (2004) Faseb J , vol.18 , pp. 902-904
    • Ho, L.1    Qin, W.2    Pompl, P.N.3    Xiang, Z.4    Wang, J.5    Zhao, Z.6
  • 5
    • 10944228564 scopus 로고    scopus 로고
    • Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: Implications for Alzheimer's disease intervention
    • L. Zhao, B. Teter, T. Morihara, G.P. Lim, S.S. Ambegaokar, and O.J. Ubeda Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention J Neurosci 24 2004 11120 11126
    • (2004) J Neurosci , vol.24 , pp. 11120-11126
    • Zhao, L.1    Teter, B.2    Morihara, T.3    Lim, G.P.4    Ambegaokar, S.S.5    Ubeda, O.J.6
  • 6
    • 84872580306 scopus 로고    scopus 로고
    • Insulin and Alzheimer's disease: Untangling the web
    • S. Craft, B. Cholerton, and L.D. Baker Insulin and Alzheimer's disease: untangling the web J Alzheimers Dis 33 Suppl 1 2013 S263 S275
    • (2013) J Alzheimers Dis , vol.33 , pp. S263-S275
    • Craft, S.1    Cholerton, B.2    Baker, L.D.3
  • 8
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • K. Talbot, H.Y. Wang, H. Kazi, L.Y. Han, K.P. Bakshi, and A. Stucky Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline J Clin Invest 122 2012 1316 1338
    • (2012) J Clin Invest , vol.122 , pp. 1316-1338
    • Talbot, K.1    Wang, H.Y.2    Kazi, H.3    Han, L.Y.4    Bakshi, K.P.5    Stucky, A.6
  • 9
    • 84055193428 scopus 로고    scopus 로고
    • Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease
    • S.M. de la Monte Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease Drugs 72 2012 49 66
    • (2012) Drugs , vol.72 , pp. 49-66
    • De La Monte, S.M.1
  • 12
    • 84859068426 scopus 로고    scopus 로고
    • Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly
    • C. Benedict, S.J. Brooks, J. Kullberg, J. Burgos, M.J. Kempton, and R. Nordenskjold Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly Diabetes care 35 2012 488 494
    • (2012) Diabetes Care , vol.35 , pp. 488-494
    • Benedict, C.1    Brooks, S.J.2    Kullberg, J.3    Burgos, J.4    Kempton, M.J.5    Nordenskjold, R.6
  • 13
    • 78651274000 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
    • L.D. Baker, D.J. Cross, S. Minoshima, D. Belongia, G.S. Watson, and S. Craft Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes Arch Neurol 68 2011 51 57
    • (2011) Arch Neurol , vol.68 , pp. 51-57
    • Baker, L.D.1    Cross, D.J.2    Minoshima, S.3    Belongia, D.4    Watson, G.S.5    Craft, S.6
  • 14
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 16
    • 28444490337 scopus 로고    scopus 로고
    • Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's Prevention
    • M.A. Sager, B. Hermann, and A. La Rue Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's Prevention J Geriatr Psychiatry Neurol 18 2005 245 249
    • (2005) J Geriatr Psychiatry Neurol , vol.18 , pp. 245-249
    • Sager, M.A.1    Hermann, B.2    La Rue, A.3
  • 17
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • G.M. McKhann, D.S. Knopman, H. Chertkow, B.T. Hyman, C.R. Jack Jr., and C.H. Kawas The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 263 269
    • (2011) Alzheimers Dement , vol.7 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3    Hyman, B.T.4    Jack, C.R.5    Kawas, C.H.6
  • 24
    • 79960770002 scopus 로고    scopus 로고
    • The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE epsilon3/epsilon3 genotype
    • S.C. Johnson, A. La Rue, B.P. Hermann, G. Xu, R.L. Koscik, and E.M. Jonaitis The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE epsilon3/epsilon3 genotype Alzheimers Dement 7 2011 456 465
    • (2011) Alzheimers Dement , vol.7 , pp. 456-465
    • Johnson, S.C.1    La Rue, A.2    Hermann, B.P.3    Xu, G.4    Koscik, R.L.5    Jonaitis, E.M.6
  • 26
    • 0033623450 scopus 로고    scopus 로고
    • Radiotracer synthesis from [(11)C]-iodomethane: A remarkably simple captive solvent method
    • A.A. Wilson, A. Garcia, L. Jin, and S. Houle Radiotracer synthesis from [(11)C]-iodomethane: a remarkably simple captive solvent method Nucl Med Biol 27 2000 529 532
    • (2000) Nucl Med Biol , vol.27 , pp. 529-532
    • Wilson, A.A.1    Garcia, A.2    Jin, L.3    Houle, S.4
  • 28
    • 33644876596 scopus 로고    scopus 로고
    • Simplified quantification of Pittsburgh compound B amyloid imaging PET studies: A comparative analysis
    • B.J. Lopresti, W.E. Klunk, C.A. Mathis, J.A. Hoge, S.K. Ziolko, and X. Lu Simplified quantification of Pittsburgh compound B amyloid imaging PET studies: a comparative analysis J Nucl Med 46 2005 1959 1972
    • (2005) J Nucl Med , vol.46 , pp. 1959-1972
    • Lopresti, B.J.1    Klunk, W.E.2    Mathis, C.A.3    Hoge, J.A.4    Ziolko, S.K.5    Lu, X.6
  • 30
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedure
    • S. Holm A simple sequentially rejective multiple test procedure Scand J Statist 6 1979 65 70
    • (1979) Scand J Statist , vol.6 , pp. 65-70
    • Holm, S.1
  • 31
    • 70350266228 scopus 로고    scopus 로고
    • Amyloid imaging in aging and dementia: Testing the amyloid hypothesis in vivo
    • G.D. Rabinovici, and W.J. Jagust Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo Behav Neurol 21 2009 117 128
    • (2009) Behav Neurol , vol.21 , pp. 117-128
    • Rabinovici, G.D.1    Jagust, W.J.2
  • 32
    • 84883824146 scopus 로고    scopus 로고
    • Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging
    • M. Thambisetty, E. Jeffrey Metter, A. Yang, H. Dolan, C. Marano, and A.B. Zonderman Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging JAMA neurology 70 2013 1167 1172
    • (2013) JAMA Neurology , vol.70 , pp. 1167-1172
    • Thambisetty, M.1    Jeffrey Metter, E.2    Yang, A.3    Dolan, H.4    Marano, C.5    Zonderman, A.B.6
  • 33
    • 84868094595 scopus 로고    scopus 로고
    • Brain insulin signaling and Alzheimer's disease: Current evidence and future directions
    • H.B. Schioth, S. Craft, S.J. Brooks, W.H. Frey 2nd, and C. Benedict Brain insulin signaling and Alzheimer's disease: current evidence and future directions Mol Neurobiol 46 2012 4 10
    • (2012) Mol Neurobiol , vol.46 , pp. 4-10
    • Schioth, H.B.1    Craft, S.2    Brooks, S.J.3    Frey, W.H.4    Benedict, C.5
  • 34
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • S. Craft, and G.S. Watson Insulin and neurodegenerative disease: shared and specific mechanisms Lancet Neurol 3 2004 169 178
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 35
    • 0036311771 scopus 로고    scopus 로고
    • The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review
    • S. Hoyer The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review J Neural Transm 109 2002 991 1002
    • (2002) J Neural Transm , vol.109 , pp. 991-1002
    • Hoyer, S.1
  • 36
  • 37
    • 0031770455 scopus 로고    scopus 로고
    • Endotheliopathy precedes type 2 diabetes
    • J.E. Tooke, and K.L. Goh Endotheliopathy precedes type 2 diabetes Diabetes care 21 1998 2047 2049
    • (1998) Diabetes Care , vol.21 , pp. 2047-2049
    • Tooke, J.E.1    Goh, K.L.2
  • 38
    • 28444485941 scopus 로고    scopus 로고
    • Links between cognitive impairment in insulin resistance: An explanatory model
    • A. Convit Links between cognitive impairment in insulin resistance: an explanatory model Neurobiol Aging 26 Suppl 1 2005 31 35
    • (2005) Neurobiol Aging , vol.26 , pp. 31-35
    • Convit, A.1
  • 39
    • 66149084048 scopus 로고    scopus 로고
    • Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
    • E.M. Reiman, K. Chen, X. Liu, D. Bandy, M. Yu, and W. Lee Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease Proc Natl Acad Sci U S A 106 2009 6820 6825
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6820-6825
    • Reiman, E.M.1    Chen, K.2    Liu, X.3    Bandy, D.4    Yu, M.5    Lee, W.6
  • 40
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • J.C. Morris, C.M. Roe, C. Xiong, A.M. Fagan, A.M. Goate, and D.M. Holtzman APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging Ann Neurol 67 2010 122 131
    • (2010) Ann Neurol , vol.67 , pp. 122-131
    • Morris, J.C.1    Roe, C.M.2    Xiong, C.3    Fagan, A.M.4    Goate, A.M.5    Holtzman, D.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.