-
1
-
-
27844525479
-
Chemical constituents of marijuana: the complex mixture of natural cannabinoids
-
COI: 1:CAS:528:DC%2BD2MXht1ejsrfJ, PID: 16199061
-
Elsohly MA, Slade D. Chemical constituents of marijuana: the complex mixture of natural cannabinoids. Life Sci 2005;78:539–548.
-
(2005)
Life Sci
, vol.78
, pp. 539-548
-
-
Elsohly, M.A.1
Slade, D.2
-
2
-
-
34548515940
-
Cannabidiol—recent advances
-
COI: 1:CAS:528:DC%2BD2sXhtVelsL%2FP, PID: 17712814
-
Mechoulam R, Peters M, Murillo-Rodriguez E, Hanus LO. Cannabidiol—recent advances. Chem Biodivers 2007;4:1678–1692.
-
(2007)
Chem Biodivers
, vol.4
, pp. 1678-1692
-
-
Mechoulam, R.1
Peters, M.2
Murillo-Rodriguez, E.3
Hanus, L.O.4
-
3
-
-
77952314867
-
Potency trends of Δ9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008
-
COI: 1:CAS:528:DC%2BC3cXht1CltbjO, PID: 20487147
-
Mehmedic Z, Chandra S, Slade D, et al. Potency trends of Δ9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008. J Forensic Sci 2010;55:1209–1217.
-
(2010)
J Forensic Sci
, vol.55
, pp. 1209-1217
-
-
Mehmedic, Z.1
Chandra, S.2
Slade, D.3
-
4
-
-
84902345998
-
The case for assessing cannabidiol in epilepsy
-
COI: 1:CAS:528:DC%2BC2cXpslKgt7Y%3D, PID: 24854434
-
Cilio MR, Thiele EA, Devinsky O. The case for assessing cannabidiol in epilepsy. Epilepsia 2014;55:787–790.
-
(2014)
Epilepsia
, vol.55
, pp. 787-790
-
-
Cilio, M.R.1
Thiele, E.A.2
Devinsky, O.3
-
5
-
-
84902304606
-
Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
-
COI: 1:CAS:528:DC%2BC2cXpslKgtL8%3D, PID: 24854329
-
Devinsky O, Cilio MR, Cross H, et al. Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Epilepsia 2014;55:791–802.
-
(2014)
Epilepsia
, vol.55
, pp. 791-802
-
-
Devinsky, O.1
Cilio, M.R.2
Cross, H.3
-
6
-
-
37049018127
-
The neurobiology of cocaine addiction
-
PID: 18552739
-
Nestler EJ. The neurobiology of cocaine addiction. Sci Pract Perspect 2005;3:4–10.
-
(2005)
Sci Pract Perspect
, vol.3
, pp. 4-10
-
-
Nestler, E.J.1
-
8
-
-
0037374320
-
The National Treatment Outcome Research Study (NTORS): 4–5 year follow-up results
-
PID: 12603229
-
Gossop M, Marsden J, Stewart D, Kidd T. The National Treatment Outcome Research Study (NTORS): 4–5 year follow-up results. Addiction 2003;98:291–303.
-
(2003)
Addiction
, vol.98
, pp. 291-303
-
-
Gossop, M.1
Marsden, J.2
Stewart, D.3
Kidd, T.4
-
9
-
-
34548751955
-
Cocaine craving as a predictor of treatment attrition and outcomes after residential treatment for cocaine dependence
-
PID: 17690796
-
Rohsenow DJ, Martin RA, Eaton CA, Monti PM. Cocaine craving as a predictor of treatment attrition and outcomes after residential treatment for cocaine dependence. J Stud Alcohol Drugs 2007;68:641–648.
-
(2007)
J Stud Alcohol Drugs
, vol.68
, pp. 641-648
-
-
Rohsenow, D.J.1
Martin, R.A.2
Eaton, C.A.3
Monti, P.M.4
-
10
-
-
77955469421
-
Daily life hour by hour, with and without cocaine: an ecological momentary assessment study
-
COI: 1:CAS:528:DC%2BC3cXntFGlsbk%3D, PID: 20532873
-
Epstein DH, Preston KL. Daily life hour by hour, with and without cocaine: an ecological momentary assessment study. Psychopharmacology 2010;211:223–232.
-
(2010)
Psychopharmacology
, vol.211
, pp. 223-232
-
-
Epstein, D.H.1
Preston, K.L.2
-
11
-
-
39149106108
-
Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers
-
COI: 1:CAS:528:DC%2BD1cXhvVykt7w%3D, PID: 17568398
-
Fox HC, Hong KI, Siedlarz K, Sinha R. Enhanced sensitivity to stress and drug/alcohol craving in abstinent cocaine-dependent individuals compared to social drinkers. Neuropsychopharmacology 2008;33:796–805.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 796-805
-
-
Fox, H.C.1
Hong, K.I.2
Siedlarz, K.3
Sinha, R.4
-
12
-
-
38349023316
-
Craving predicts time to cocaine relapse: further validation of the Now and Brief versions of the cocaine craving questionnaire
-
COI: 1:CAS:528:DC%2BD1cXptlarsw%3D%3D, PID: 18063320
-
Paliwal P, Hyman SM, Sinha R. Craving predicts time to cocaine relapse: further validation of the Now and Brief versions of the cocaine craving questionnaire. Drug Alcohol Depend 2008;93:252–259.
-
(2008)
Drug Alcohol Depend
, vol.93
, pp. 252-259
-
-
Paliwal, P.1
Hyman, S.M.2
Sinha, R.3
-
13
-
-
58149493073
-
Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use
-
PID: 19124692
-
Epstein DH, Willner-Reid J, Vahabzadeh M, et al. Real-time electronic diary reports of cue exposure and mood in the hours before cocaine and heroin craving and use. Arch Gen Psychiatry 2009;66:88–94.
-
(2009)
Arch Gen Psychiatry
, vol.66
, pp. 88-94
-
-
Epstein, D.H.1
Willner-Reid, J.2
Vahabzadeh, M.3
-
15
-
-
33644753922
-
Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes
-
PID: 16520439
-
Sinha R, Garcia M, Paliwal P, Kreek MJ, Rounsaville BJ. Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes. Arch Gen Psychiatry 2006;63:324–331.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 324-331
-
-
Sinha, R.1
Garcia, M.2
Paliwal, P.3
Kreek, M.J.4
Rounsaville, B.J.5
-
16
-
-
41549148459
-
Psychosocial interventions for cocaine and psychostimulant amphetamines related disorders
-
Knapp WP, Soares BG, Farrel M, Lima MS. Psychosocial interventions for cocaine and psychostimulant amphetamines related disorders. Cochrane Database Syst Rev 2007:CD003023.
-
(2007)
Cochrane Database Syst Rev
, pp. CD003023
-
-
Knapp, W.P.1
Soares, B.G.2
Farrel, M.3
Lima, M.S.4
-
20
-
-
84924840368
-
Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial
-
COI: 1:CAS:528:DC%2BC2cXnslGrtL8%3D, PID: 24793366
-
Kosten TR, Domingo CB, Shorter D, et al. Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial. Drug Alcohol Depend 2014;140:42–47.
-
(2014)
Drug Alcohol Depend
, vol.140
, pp. 42-47
-
-
Kosten, T.R.1
Domingo, C.B.2
Shorter, D.3
-
21
-
-
84922398714
-
Adjuvants for vaccines to drugs of abuse and addiction
-
COI: 1:CAS:528:DC%2BC2cXhtlGgu7vF, PID: 25111169
-
Alving CR, Matyas GR, Torres O, Jalah R, Beck Z. Adjuvants for vaccines to drugs of abuse and addiction. Vaccine 2014;32:5382–5389.
-
(2014)
Vaccine
, vol.32
, pp. 5382-5389
-
-
Alving, C.R.1
Matyas, G.R.2
Torres, O.3
Jalah, R.4
Beck, Z.5
-
22
-
-
0035112869
-
Ultrastructural localization of the CB1 cannabinoid receptor in mu- opioid receptor patches of the rat Caudate putamen nucleus
-
COI: 1:CAS:528:DC%2BD3MXhtF2qu70%3D, PID: 11157068
-
Rodriguez JJ, Mackie K, Pickel VM. Ultrastructural localization of the CB1 cannabinoid receptor in mu- opioid receptor patches of the rat Caudate putamen nucleus. J Neurosci 2001;21:823–833.
-
(2001)
J Neurosci
, vol.21
, pp. 823-833
-
-
Rodriguez, J.J.1
Mackie, K.2
Pickel, V.M.3
-
23
-
-
84915754556
-
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
-
COI: 1:CAS:528:DC%2BC2cXhvVGksbrF, PID: 25368177
-
Zhang HY, Gao M, Liu QR, et al. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proc Natl Acad Sci U S A 2014;111:E5007-E5015.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E5007-E5015
-
-
Zhang, H.Y.1
Gao, M.2
Liu, Q.R.3
-
24
-
-
80052213796
-
Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice
-
COI: 1:CAS:528:DC%2BC3MXptlalsbo%3D, PID: 21785434
-
Xi ZX, Peng XQ, Li X, et al. Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice. Nat Neurosci 2011;14:1160–1166.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1160-1166
-
-
Xi, Z.X.1
Peng, X.Q.2
Li, X.3
-
25
-
-
38349158960
-
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin
-
COI: 1:CAS:528:DC%2BD1cXovFCkuw%3D%3D, PID: 17828291
-
Pertwee RG. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. Br J Pharmacol 2008;153:199–215.
-
(2008)
Br J Pharmacol
, vol.153
, pp. 199-215
-
-
Pertwee, R.G.1
-
26
-
-
33847653702
-
Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro
-
COI: 1:CAS:528:DC%2BD2sXisVeis7Y%3D, PID: 17245363
-
Thomas A, Baillie GL, Phillips AM, et al. Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. Br J Pharmacol 2007;150:613–623.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 613-623
-
-
Thomas, A.1
Baillie, G.L.2
Phillips, A.M.3
-
27
-
-
46749129338
-
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
-
COI: 1:CAS:528:DC%2BD1cXns1ynsr0%3D, PID: 18550765
-
Qin N, Neeper MP, Liu Y, et al. TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J Neurosci 2008;28:6231–6238.
-
(2008)
J Neurosci
, vol.28
, pp. 6231-6238
-
-
Qin, N.1
Neeper, M.P.2
Liu, Y.3
-
28
-
-
0034751335
-
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
-
COI: 1:CAS:528:DC%2BD3MXotlChsbk%3D, PID: 11606325
-
Bisogno T, Hanus L, De Petrocellis L, et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol 2001;134:845–852.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 845-852
-
-
Bisogno, T.1
Hanus, L.2
De Petrocellis, L.3
-
29
-
-
46649094780
-
Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats
-
COI: 1:CAS:528:DC%2BD1cXotV2nu7g%3D, PID: 18446323
-
Campos AC, Guimaraes FS. Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology 2008;199:223–230.
-
(2008)
Psychopharmacology
, vol.199
, pp. 223-230
-
-
Campos, A.C.1
Guimaraes, F.S.2
-
30
-
-
77249134168
-
Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
-
COI: 1:CAS:528:DC%2BC3cXjtF2hsLY%3D, PID: 20128798
-
Magen I, Avraham Y, Ackerman Z, et al. Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. Br J Pharmacol 2010;159:950–957.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 950-957
-
-
Magen, I.1
Avraham, Y.2
Ackerman, Z.3
-
31
-
-
27644440716
-
Agonistic properties of cannabidiol at 5-HT1a receptors
-
COI: 1:CAS:528:DC%2BD2MXhtFKmsbrE, PID: 16258853
-
Russo EB, Burnett A, Hall B, Parker KK. Agonistic properties of cannabidiol at 5-HT1a receptors. Neurochem Res 2005;30:1037–1043.
-
(2005)
Neurochem Res
, vol.30
, pp. 1037-1043
-
-
Russo, E.B.1
Burnett, A.2
Hall, B.3
Parker, K.K.4
-
32
-
-
77954145403
-
Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors
-
COI: 1:CAS:528:DC%2BC3cXosVWmsr0%3D, PID: 20621717
-
Alves FH, Crestani CC, Gomes FV, et al. Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors. Pharmacol Res 2010;62:228–236.
-
(2010)
Pharmacol Res
, vol.62
, pp. 228-236
-
-
Alves, F.H.1
Crestani, C.C.2
Gomes, F.V.3
-
33
-
-
84856432211
-
Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors
-
COI: 1:CAS:528:DC%2BC38XjtFKisbc%3D, PID: 21148020
-
Gomes FV, Reis DG, Alves FH, et al. Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors. J Psychopharmacol 2012;26:104–113.
-
(2012)
J Psychopharmacol
, vol.26
, pp. 104-113
-
-
Gomes, F.V.1
Reis, D.G.2
Alves, F.H.3
-
34
-
-
77953917373
-
Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors
-
PID: 20457188
-
Soares Vde P, Campos AC, Bortoli VC, et al. Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. Behav Brain Res 2010;213:225–229.
-
(2010)
Behav Brain Res
, vol.213
, pp. 225-229
-
-
Soares Vde, P.1
Campos, A.C.2
Bortoli, V.C.3
-
35
-
-
74549165354
-
Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
-
COI: 1:CAS:528:DC%2BC3cXhtFynt7w%3D, PID: 20002102
-
Zanelati TV, Biojone C, Moreira FA, Guimaraes FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. Br J Pharmacol 2010;159:122–128.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 122-128
-
-
Zanelati, T.V.1
Biojone, C.2
Moreira, F.A.3
Guimaraes, F.S.4
Joca, S.R.5
-
36
-
-
79952535110
-
Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum
-
COI: 1:CAS:528:DC%2BC3MXjtFKisLc%3D, PID: 21266173
-
Pandolfo P, Silveirinha V, dos Santos-Rodrigues A, et al. Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum. Eur J Pharmacol 2011;655:38–45.
-
(2011)
Eur J Pharmacol
, vol.655
, pp. 38-45
-
-
Pandolfo, P.1
Silveirinha, V.2
dos Santos-Rodrigues, A.3
-
37
-
-
33644540495
-
Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors
-
COI: 1:CAS:528:DC%2BD28XhslOkurg%3D, PID: 16489449
-
Kathmann M, Flau K, Redmer A, Trankle C, Schlicker E. Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors. Naunyn Schmiedebergs Arch Pharmacol 2006;372:354–361.
-
(2006)
Naunyn Schmiedebergs Arch Pharmacol
, vol.372
, pp. 354-361
-
-
Kathmann, M.1
Flau, K.2
Redmer, A.3
Trankle, C.4
Schlicker, E.5
-
38
-
-
33646734889
-
Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression
-
COI: 1:CAS:528:DC%2BD28XlsVGksbo%3D, PID: 16672367
-
Carrier EJ, Auchampach JA, Hillard CJ. Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proc Natl Acad Sci U S A 2006;103:7895–7900.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7895-7900
-
-
Carrier, E.J.1
Auchampach, J.A.2
Hillard, C.J.3
-
39
-
-
0032493197
-
Cannabidiol and (−)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
-
COI: 1:CAS:528:DyaK1cXks1SltL0%3D, PID: 9653176
-
Hampson AJ, Grimaldi M, Axelrod J, Wink D. Cannabidiol and (−)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc Natl Acad Sci U S A 1998;95:8268–8273.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8268-8273
-
-
Hampson, A.J.1
Grimaldi, M.2
Axelrod, J.3
Wink, D.4
-
40
-
-
78650961973
-
The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects
-
COI: 1:CAS:528:DC%2BC3MXjsFSktg%3D%3D, PID: 21062637
-
Hallak JE, Dursun SM, Bosi DC, et al. The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. Prog Neuropsychopharmacol Biol Psychiatry 2011;35:198–202.
-
(2011)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.35
, pp. 198-202
-
-
Hallak, J.E.1
Dursun, S.M.2
Bosi, D.C.3
-
41
-
-
0025266290
-
Antianxiety effect of cannabidiol in the elevated plus-maze
-
COI: 1:CAS:528:DyaK3cXhvFWrsb0%3D, PID: 1969666
-
Guimaraes FS, Chiaretti TM, Graeff FG, Zuardi AW. Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology 1990;100:558–559.
-
(1990)
Psychopharmacology
, vol.100
, pp. 558-559
-
-
Guimaraes, F.S.1
Chiaretti, T.M.2
Graeff, F.G.3
Zuardi, A.W.4
-
42
-
-
0028089295
-
Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze
-
COI: 1:CAS:528:DyaK2cXis1WjtrY%3D, PID: 7913072
-
Guimaraes FS, de Aguiar JC, Mechoulam R, Breuer A. Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze. Gen Pharmacol 1994;25:161–164.
-
(1994)
Gen Pharmacol
, vol.25
, pp. 161-164
-
-
Guimaraes, F.S.1
de Aguiar, J.C.2
Mechoulam, R.3
Breuer, A.4
-
44
-
-
80051799165
-
Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress
-
COI: 1:CAS:528:DC%2BC3MXhtVWqur%2FN, PID: 21771609
-
Granjeiro EM, Gomes FV, Guimaraes FS, Correa FM, Resstel LB. Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. Pharmacol Biochem Behav 2011;99:743–748.
-
(2011)
Pharmacol Biochem Behav
, vol.99
, pp. 743-748
-
-
Granjeiro, E.M.1
Gomes, F.V.2
Guimaraes, F.S.3
Correa, F.M.4
Resstel, L.B.5
-
45
-
-
84856053335
-
Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm
-
COI: 1:CAS:528:DC%2BC3MXhs1eju7rI, PID: 21918503
-
Uribe-Marino A, Francisco A, Castiblanco-Urbina MA, et al. Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm. Neuropsychopharmacology 2012;37:412–421.
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 412-421
-
-
Uribe-Marino, A.1
Francisco, A.2
Castiblanco-Urbina, M.A.3
-
46
-
-
84856644638
-
Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
-
COI: 1:CAS:528:DC%2BC3MXhtVOrtb7E
-
Fagherazzi EV, Garcia VA, Maurmann N, et al. Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. Psychopharmacology (Berl) 2012;219:1133–1140.
-
(2012)
Psychopharmacology (Berl)
, vol.219
, pp. 1133-1140
-
-
Fagherazzi, E.V.1
Garcia, V.A.2
Maurmann, N.3
-
47
-
-
79952378224
-
Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice
-
COI: 1:CAS:528:DC%2BC3MXivF2lurk%3D, PID: 21182490
-
Avraham Y, Grigoriadis N, Poutahidis T, et al. Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. Br J Pharmacol 2011;162:1650–1658.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 1650-1658
-
-
Avraham, Y.1
Grigoriadis, N.2
Poutahidis, T.3
-
48
-
-
77955690718
-
Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture
-
PID: 20561509
-
Cassol-Jr OJ, Comim CM, Silva BR, et al. Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. Brain Res 2010;1348:128–138.
-
(2010)
Brain Res
, vol.1348
, pp. 128-138
-
-
Cassol-Jr, O.J.1
Comim, C.M.2
Silva, B.R.3
-
49
-
-
77952551436
-
Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L
-
COI: 1:CAS:528:DC%2BC3cXlvVGlsLc%3D, PID: 20332000
-
El-Alfy AT, Ivey K, Robinson K, et al. Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav 2010;95:434–442.
-
(2010)
Pharmacol Biochem Behav
, vol.95
, pp. 434-442
-
-
El-Alfy, A.T.1
Ivey, K.2
Robinson, K.3
-
50
-
-
84856628201
-
Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour
-
COI: 1:CAS:528:DC%2BC3MXpsVajtLw%3D
-
Deiana S, Watanabe A, Yamasaki Y, et al. Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Delta(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour. Psychopharmacology (Berl) 2012;219:859–873.
-
(2012)
Psychopharmacology (Berl)
, vol.219
, pp. 859-873
-
-
Deiana, S.1
Watanabe, A.2
Yamasaki, Y.3
-
51
-
-
77955168120
-
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
-
COI: 1:CAS:528:DC%2BC3cXptVyrtLs%3D, PID: 20695034
-
Casarotto PC, Gomes FV, Resstel LB, Guimaraes FS. Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. Behav Pharmacol 2010;21:353–358.
-
(2010)
Behav Pharmacol
, vol.21
, pp. 353-358
-
-
Casarotto, P.C.1
Gomes, F.V.2
Resstel, L.B.3
Guimaraes, F.S.4
-
52
-
-
0031834159
-
Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity
-
COI: 1:CAS:528:DyaK1cXjs12nu7s%3D, PID: 9630465
-
Bornheim LM. Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity. Toxicol Appl Pharmacol 1998;150:158–165.
-
(1998)
Toxicol Appl Pharmacol
, vol.150
, pp. 158-165
-
-
Bornheim, L.M.1
-
53
-
-
22944458873
-
Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
-
COI: 1:CAS:528:DC%2BD2MXntVSisLk%3D, PID: 15878999
-
Hamelink C, Hampson A, Wink DA, Eiden LE, Eskay RL. Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity. J Pharmacol Exp Ther 2005;314:780–788.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 780-788
-
-
Hamelink, C.1
Hampson, A.2
Wink, D.A.3
Eiden, L.E.4
Eskay, R.L.5
-
54
-
-
0022351916
-
Effects and interactions of natural cannabinoids on the isolated heart
-
COI: 1:CAS:528:DyaL2MXmtVKgtrs%3D, PID: 4048169
-
Nahas G, Trouve R. Effects and interactions of natural cannabinoids on the isolated heart. Proc Soc Exp Biol Med 1985;180:312–316.
-
(1985)
Proc Soc Exp Biol Med
, vol.180
, pp. 312-316
-
-
Nahas, G.1
Trouve, R.2
-
55
-
-
0021015357
-
Antagonistic effects of two natural cannabinoids on the isolated heart
-
COI: 1:STN:280:DyaL2c7gsF2qtA%3D%3D, PID: 6318927, (in Frecnh)
-
Trouve R, Nahas G, Stuker O, Latour C. [Antagonistic effects of two natural cannabinoids on the isolated heart]. C R Seances Acad Sci III 1983;297:191–194 (in Frecnh).
-
(1983)
C R Seances Acad Sci III
, vol.297
, pp. 191-194
-
-
Trouve, R.1
Nahas, G.2
Stuker, O.3
Latour, C.4
-
56
-
-
77957228353
-
A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice
-
COI: 1:CAS:528:DC%2BC3cXpt1Gjsbg%3D, PID: 19785914
-
Long LE, Chesworth R, Huang XF, et al. A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. Int J Neuropsychopharmacol 2010;13:861–876.
-
(2010)
Int J Neuropsychopharmacol
, vol.13
, pp. 861-876
-
-
Long, L.E.1
Chesworth, R.2
Huang, X.F.3
-
57
-
-
10744224906
-
Effects of cannabidiol (CBD) on regional cerebral blood flow
-
COI: 1:CAS:528:DC%2BD2cXksl2gsA%3D%3D, PID: 14583744
-
Crippa JA, Zuardi AW, Garrido GE, et al. Effects of cannabidiol (CBD) on regional cerebral blood flow. Neuropsychopharmacology 2004;29:417–426.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 417-426
-
-
Crippa, J.A.1
Zuardi, A.W.2
Garrido, G.E.3
-
58
-
-
33748320954
-
Cannabidiol monotherapy for treatment-resistant schizophrenia
-
COI: 1:CAS:528:DC%2BD28XhtVOht7fM, PID: 16401651
-
Zuardi AW, Hallak JE, Dursun SM, et al. Cannabidiol monotherapy for treatment-resistant schizophrenia. J Psychopharmacol 2006;20:683–686.
-
(2006)
J Psychopharmacol
, vol.20
, pp. 683-686
-
-
Zuardi, A.W.1
Hallak, J.E.2
Dursun, S.M.3
-
59
-
-
76249132113
-
Cannabidiol was ineffective for manic episode of bipolar affective disorder
-
COI: 1:CAS:528:DC%2BC3cXjtV2isrw%3D, PID: 18801823
-
Zuardi A, Crippa J, Dursun S, et al. Cannabidiol was ineffective for manic episode of bipolar affective disorder. J Psychopharmacol 2010;24:135–137.
-
(2010)
J Psychopharmacol
, vol.24
, pp. 135-137
-
-
Zuardi, A.1
Crippa, J.2
Dursun, S.3
-
60
-
-
0028881791
-
Antipsychotic effect of cannabidiol
-
COI: 1:STN:280:DyaK28%2FhvF2itA%3D%3D, PID: 7559378
-
Zuardi AW, Morais SL, Guimaraes FS, Mechoulam R. Antipsychotic effect of cannabidiol. J Clin Psychiatry 1995;56:485–486.
-
(1995)
J Clin Psychiatry
, vol.56
, pp. 485-486
-
-
Zuardi, A.W.1
Morais, S.L.2
Guimaraes, F.S.3
Mechoulam, R.4
-
61
-
-
84923164414
-
A systematic review of the antipsychotic properties of cannabidiol in humans
-
PID: 25667194
-
Iseger TA, Bossong MG. A systematic review of the antipsychotic properties of cannabidiol in humans. Schizophr Res 2015;162:153–161.
-
(2015)
Schizophr Res
, vol.162
, pp. 153-161
-
-
Iseger, T.A.1
Bossong, M.G.2
-
62
-
-
78650625479
-
Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
-
COI: 1:CAS:528:DC%2BC3MXit1yitro%3D, PID: 20829306
-
Crippa JA, Derenusson GN, Ferrari TB, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol 2011;25:121–130.
-
(2011)
J Psychopharmacol
, vol.25
, pp. 121-130
-
-
Crippa, J.A.1
Derenusson, G.N.2
Ferrari, T.B.3
-
63
-
-
0020079139
-
Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects
-
COI: 1:CAS:528:DyaL38XktFKlu74%3D, PID: 6285406
-
Zuardi AW, Shirakawa I, Finkelfarb E, Karniol IG. Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects. Psychopharmacology 1982;76:245–250.
-
(1982)
Psychopharmacology
, vol.76
, pp. 245-250
-
-
Zuardi, A.W.1
Shirakawa, I.2
Finkelfarb, E.3
Karniol, I.G.4
-
64
-
-
79954608618
-
Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients
-
COI: 1:CAS:528:DC%2BC3MXks1Wltrk%3D, PID: 21307846
-
Bergamaschi MM, Queiroz RH, Chagas MH, et al. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients. Neuropsychopharmacology 2011;36:1219–1226.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 1219-1226
-
-
Bergamaschi, M.M.1
Queiroz, R.H.2
Chagas, M.H.3
-
65
-
-
58149520644
-
Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
-
COI: 1:CAS:528:DC%2BD1MXhslSrur8%3D, PID: 19124693
-
Fusar-Poli P, Crippa JA, Bhattacharyya S, et al. Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Arch Gen Psychiatry 2009;66:95–105.
-
(2009)
Arch Gen Psychiatry
, vol.66
, pp. 95-105
-
-
Fusar-Poli, P.1
Crippa, J.A.2
Bhattacharyya, S.3
-
66
-
-
84863730498
-
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
-
PID: 22729452
-
Schier AR, Ribeiro NP, Silva AC, et al. Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug. Rev Bras Psiquiatr 2012;34(Suppl. 1):S104-S110.
-
(2012)
Rev Bras Psiquiatr
, vol.34
, pp. S104-S110
-
-
Schier, A.R.1
Ribeiro, N.P.2
Silva, A.C.3
-
67
-
-
41149089597
-
Glutamate release in the nucleus accumbens core is necessary for heroin seeking
-
COI: 1:CAS:528:DC%2BD1cXjvFCjsbc%3D, PID: 18354020
-
LaLumiere RT, Kalivas PW. Glutamate release in the nucleus accumbens core is necessary for heroin seeking. J Neurosci 2008;28:3170–3177.
-
(2008)
J Neurosci
, vol.28
, pp. 3170-3177
-
-
LaLumiere, R.T.1
Kalivas, P.W.2
-
68
-
-
51349141952
-
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
-
COI: 1:CAS:528:DC%2BD1cXhtVyms7vM, PID: 18776886
-
Katona I, Freund TF. Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nat Med 2008;14:923–930.
-
(2008)
Nat Med
, vol.14
, pp. 923-930
-
-
Katona, I.1
Freund, T.F.2
-
69
-
-
5444220592
-
Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats
-
COI: 1:CAS:528:DC%2BD2cXotVOhtr0%3D
-
Parker LA, Burton P, Sorge RE, Yakiwchuk C, Mechoulam R. Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats. Psychopharmacology (Berl) 2004;175:360–366.
-
(2004)
Psychopharmacology (Berl)
, vol.175
, pp. 360-366
-
-
Parker, L.A.1
Burton, P.2
Sorge, R.E.3
Yakiwchuk, C.4
Mechoulam, R.5
-
70
-
-
39149092685
-
Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol
-
COI: 1:CAS:528:DC%2BD1cXisVWiu7c%3D, PID: 18206320
-
Vann RE, Gamage TF, Warner JA, et al. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug Alcohol Depend 2008;94:191–198.
-
(2008)
Drug Alcohol Depend
, vol.94
, pp. 191-198
-
-
Vann, R.E.1
Gamage, T.F.2
Warner, J.A.3
-
71
-
-
84874413463
-
Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus
-
COI: 1:CAS:528:DC%2BC3sXjsFKmsb0%3D, PID: 22862835
-
Katsidoni V, Anagnostou I, Panagis G. Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus. Addict Biol 2013;18:286–296.
-
(2013)
Addict Biol
, vol.18
, pp. 286-296
-
-
Katsidoni, V.1
Anagnostou, I.2
Panagis, G.3
-
72
-
-
72449197981
-
Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
-
COI: 1:CAS:528:DC%2BD1MXhsFCgtLzO, PID: 19940171
-
Ren Y, Whittard J, Higuera-Matas A, Morris CV, Hurd YL. Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances. J Neurosci 2009;29:14764–14769.
-
(2009)
J Neurosci
, vol.29
, pp. 14764-14769
-
-
Ren, Y.1
Whittard, J.2
Higuera-Matas, A.3
Morris, C.V.4
Hurd, Y.L.5
-
73
-
-
59349110023
-
Glutamate and reinstatement
-
COI: 1:CAS:528:DC%2BD1MXhsFKks78%3D, PID: 19157986
-
Knackstedt LA, Kalivas PW. Glutamate and reinstatement. Curr Opin Pharmacol 2009;9:59–64.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 59-64
-
-
Knackstedt, L.A.1
Kalivas, P.W.2
-
74
-
-
0016588164
-
Interactions between cannabidiol and delta9-THC during abstinence in morphine-dependent rats
-
COI: 1:CAS:528:DyaE28Xjs1E%3D, PID: 1238886
-
Hine B, Torrelio M, Gershon S. Interactions between cannabidiol and delta9-THC during abstinence in morphine-dependent rats. Life Sci 1975;17:851–857.
-
(1975)
Life Sci
, vol.17
, pp. 851-857
-
-
Hine, B.1
Torrelio, M.2
Gershon, S.3
-
75
-
-
0016778717
-
Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats
-
COI: 1:CAS:528:DyaE2MXmtVWqsbs%3D, PID: 1237925
-
Hine B, Torrelio M, Gershon S. Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. Res Commun Chem Pathol Pharmacol 1975;12:185–188.
-
(1975)
Res Commun Chem Pathol Pharmacol
, vol.12
, pp. 185-188
-
-
Hine, B.1
Torrelio, M.2
Gershon, S.3
-
76
-
-
0021853064
-
The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol
-
COI: 1:CAS:528:DyaL2MXltFKiu7w%3D, PID: 2994117
-
Chesher GB, Jackson DM. The quasi-morphine withdrawal syndrome: effect of cannabinol, cannabidiol and tetrahydrocannabinol. Pharmacol Biochem Behav 1985;23:13–15.
-
(1985)
Pharmacol Biochem Behav
, vol.23
, pp. 13-15
-
-
Chesher, G.B.1
Jackson, D.M.2
-
77
-
-
0017202327
-
Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice
-
COI: 1:CAS:528:DyaE28XlslWrs7w%3D, PID: 826944
-
Bhargava HN. Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice. Psychopharmacology 1976;49:267–270.
-
(1976)
Psychopharmacology
, vol.49
, pp. 267-270
-
-
Bhargava, H.N.1
-
78
-
-
82955233174
-
Cannabidiol potentiates Delta(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats
-
COI: 1:CAS:528:DC%2BC3MXntlansrk%3D
-
Klein C, Karanges E, Spiro A, et al. Cannabidiol potentiates Delta(9)-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. Psychopharmacology (Berl) 2011;218:443–457.
-
(2011)
Psychopharmacology (Berl)
, vol.218
, pp. 443-457
-
-
Klein, C.1
Karanges, E.2
Spiro, A.3
-
79
-
-
84878345442
-
Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings
-
PID: 23685330
-
Morgan CJ, Das RK, Joye A, Curran HV, Kamboj SK. Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings. Addict Behav 2013;38:2433–2436.
-
(2013)
Addict Behav
, vol.38
, pp. 2433-2436
-
-
Morgan, C.J.1
Das, R.K.2
Joye, A.3
Curran, H.V.4
Kamboj, S.K.5
-
80
-
-
77957687873
-
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected]
-
PID: 20884951
-
Morgan CJ, Schafer G, Freeman TP, Curran HV. Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected]. Br J Psychiatry 2010;197:285–290.
-
(2010)
Br J Psychiatry
, vol.197
, pp. 285-290
-
-
Morgan, C.J.1
Schafer, G.2
Freeman, T.P.3
Curran, H.V.4
-
81
-
-
77954761129
-
Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis
-
COI: 1:CAS:528:DC%2BC3cXovFKmtro%3D, PID: 20428110
-
Morgan CJ, Freeman TP, Schafer GL, Curran HV. Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. Neuropsychopharmacology 2010;35:1879–1885.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 1879-1885
-
-
Morgan, C.J.1
Freeman, T.P.2
Schafer, G.L.3
Curran, H.V.4
-
82
-
-
84942804432
-
Safety and pharmacokinetics of oral cannabidiol when administered concomitantly with intravenous fentanyl in humans
-
COI: 1:CAS:528:DC%2BC2MXpsVWjsb0%3D, PID: 25748562
-
Manini AF, Yiannoulos G, Bergamaschi MM, et al. Safety and pharmacokinetics of oral cannabidiol when administered concomitantly with intravenous fentanyl in humans. J Addict Med 2015;9:204–210.
-
(2015)
J Addict Med
, vol.9
, pp. 204-210
-
-
Manini, A.F.1
Yiannoulos, G.2
Bergamaschi, M.M.3
-
83
-
-
77953542908
-
Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol
-
COI: 1:CAS:528:DC%2BC3cXkvFersro%3D, PID: 19775500
-
Fusar-Poli P, Allen P, Bhattacharyya S, et al. Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol. Int J Neuropsychopharmacol 2010;13:421–432.
-
(2010)
Int J Neuropsychopharmacol
, vol.13
, pp. 421-432
-
-
Fusar-Poli, P.1
Allen, P.2
Bhattacharyya, S.3
|