Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture

Brain Research

Volumn 1348, Issue , 2010, Pages 128-138

  Cassol Jr, Omar J ^a   Comim, Clarissa M ^a   Silva, Bruno R ^a   Hermani, Fernanda V ^a   Constantino, Larissa S ^a   Felisberto, Francine ^a   Petronilho, Fabricia ^a   Hallak, Jaime Eduardo C ^b   De Martinis, Bruno S ^b   Zuardi, Antonio W ^b   Crippa, José A S ^b   Quevedo, João ^a   Dal Pizzol, Felipe ^a  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cannabidiol; Memory; Mortality; Oxidative stress; Rats; Sepsis

Indexed keywords

CANNABIDIOL; CARBONYL DERIVATIVE; THIOBARBITURIC ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; HEART; HIPPOCAMPUS; KIDNEY; LUNG; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SEPSIS; SPLEEN; ANALYSIS OF VARIANCE; ANIMAL; AVOIDANCE BEHAVIOR; BRAIN; CECUM; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; MEMORY DISORDERS; MENTAL STRESS; METABOLISM; PROTEIN CARBONYLATION; PUNCTURE; TIME; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; BRAIN; CANNABIDIOL; CECUM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMORY DISORDERS; PROTEIN CARBONYLATION; PUNCTURES; RATS; RATS, WISTAR; SEPSIS; STRESS, PSYCHOLOGICAL; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 77955690718     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.06.023     Document Type: Article

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