메뉴 건너뛰기




Volumn 32, Issue 42, 2014, Pages 5382-5389

Adjuvants for vaccines to drugs of abuse and addiction

Author keywords

Adjuvants; Cocaine; Heroin; Hydrocodone; Immunotherapeutic vaccines; Methamphetamine; Morphine; Nicotine; Oxycodone

Indexed keywords

ALUMINUM HYDROXIDE; ANTIBODY; COCAINE; DIAMORPHINE; FREUND ADJUVANT; IMMUNOLOGICAL ADJUVANT; LIPOSOME; METHAMPHETAMINE; NICOTINE; OXYCODONE; PHOSPHORYL LIPID A; VACCINE; ALUMINUM DERIVATIVE; EMULSION; HAPTEN; INCOMPLETE FREUND'S ADJUVANT; LIPID; LIPID A;

EID: 84922398714     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.07.085     Document Type: Review
Times cited : (63)

References (105)
  • 1
    • 84887248421 scopus 로고    scopus 로고
    • Global burden of disease attributable to illicit drug use and dependence: findings from the Global Burden of Disease Study 2010
    • Degenhardt L., Whiteford H.A., Ferrari A.J., Baxter A.J., Charlson F.J., Hall W.D., et al. Global burden of disease attributable to illicit drug use and dependence: findings from the Global Burden of Disease Study 2010. Lancet 2013, 382(November (9904)):1564-1574.
    • (2013) Lancet , vol.382 , Issue.NOVEMBER 9904 , pp. 1564-1574
    • Degenhardt, L.1    Whiteford, H.A.2    Ferrari, A.J.3    Baxter, A.J.4    Charlson, F.J.5    Hall, W.D.6
  • 2
    • 84856756658 scopus 로고    scopus 로고
    • Mortality among young injection drug users in San Francisco: a 10-year follow-up of the UFO study
    • Evans J.L., Tsui J.I., Hahn J.A., Davidson P.J., Lum P.J., Page K. Mortality among young injection drug users in San Francisco: a 10-year follow-up of the UFO study. Am J Epidemiol 2012, 175(February (4)):302-308.
    • (2012) Am J Epidemiol , vol.175 , Issue.FEBRUARY 4 , pp. 302-308
    • Evans, J.L.1    Tsui, J.I.2    Hahn, J.A.3    Davidson, P.J.4    Lum, P.J.5    Page, K.6
  • 3
    • 0347918849 scopus 로고    scopus 로고
    • Epidemiology of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in injection drug users in Argentina: high seroprevalence of HIV infection
    • Sosa-Estáni S., Rossi D., Weissenbacher M. Epidemiology of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in injection drug users in Argentina: high seroprevalence of HIV infection. Clin Infect Dis 2003, 5(December (37 Suppl)):S338-S342.
    • (2003) Clin Infect Dis , vol.5 , Issue.DECEMBER 37 SUPPL , pp. S338-S342
    • Sosa-Estáni, S.1    Rossi, D.2    Weissenbacher, M.3
  • 5
    • 84893357751 scopus 로고    scopus 로고
    • Can you vaccinate against substance abuse?
    • Kosten T.R., Domingo C.B. Can you vaccinate against substance abuse?. Expert Opin Biol Ther 2013, 13(August (8)):1093-1097.
    • (2013) Expert Opin Biol Ther , vol.13 , Issue.AUGUST 8 , pp. 1093-1097
    • Kosten, T.R.1    Domingo, C.B.2
  • 7
    • 67449105552 scopus 로고    scopus 로고
    • Anti-drug vaccines to treat substance abuse
    • May-June 4
    • Kinsey B.M., Jackson D.C., Orson F.M. Anti-drug vaccines to treat substance abuse. Immunol Cell Biol 2009, 87(May-June (4)):309-314.
    • (2009) Immunol Cell Biol , vol.87 , pp. 309-314
    • Kinsey, B.M.1    Jackson, D.C.2    Orson, F.M.3
  • 8
    • 84655167585 scopus 로고    scopus 로고
    • Vaccines targeting drugs of abuse: is the glass half-empty or half-full?
    • Janda K.D., Treweek J.B. Vaccines targeting drugs of abuse: is the glass half-empty or half-full?. Nat Rev Immunol 2012, 12(1):67-72.
    • (2012) Nat Rev Immunol , vol.12 , Issue.1 , pp. 67-72
    • Janda, K.D.1    Treweek, J.B.2
  • 11
    • 0011786888 scopus 로고    scopus 로고
    • Antibodies
    • Mosby, Edinburgh, I. Roitt, J. Brostoff, D. Male (Eds.)
    • Turner M. Antibodies. Immunology 2011, 65-85. Mosby, Edinburgh. 6th edition. I. Roitt, J. Brostoff, D. Male (Eds.).
    • (2011) Immunology , pp. 65-85
    • Turner, M.1
  • 12
    • 0002460205 scopus 로고    scopus 로고
    • Immunogenicity and antigen structure
    • Lippincott Williams & Wilkins, Philadelphia, W.E. Paul (Ed.)
    • Berzofsky J.A., Berkower I.A. Immunogenicity and antigen structure. Fundamental immunology 2013, 539-582. Lippincott Williams & Wilkins, Philadelphia. 7th edition. W.E. Paul (Ed.).
    • (2013) Fundamental immunology , pp. 539-582
    • Berzofsky, J.A.1    Berkower, I.A.2
  • 13
    • 0014466078 scopus 로고
    • Production and specificity of antibodies directed toward 3,4,5-trimethoxyphenylethylamine, 3,4-dimethoxyphenylethylamine and 2,5-dimethoxy-4-methylamphetamine
    • Van Vunakis H., Bradvica H., Benda P., Levine L. Production and specificity of antibodies directed toward 3,4,5-trimethoxyphenylethylamine, 3,4-dimethoxyphenylethylamine and 2,5-dimethoxy-4-methylamphetamine. Biochem Pharmacol 1969, 18(February (2)):393-404.
    • (1969) Biochem Pharmacol , vol.18 , Issue.FEBRUARY 2 , pp. 393-404
    • Van Vunakis, H.1    Bradvica, H.2    Benda, P.3    Levine, L.4
  • 14
    • 0014942413 scopus 로고
    • Morphine: radioimmunoassay
    • Spector S., Parker C.W. Morphine: radioimmunoassay. Science 1970, 168(June (3937)):1347-1348.
    • (1970) Science , vol.168 , Issue.JUNE 3937 , pp. 1347-1348
    • Spector, S.1    Parker, C.W.2
  • 15
    • 0015111368 scopus 로고
    • Quantitative determination of morphine in serum by radioimmunoassay
    • Spector S. Quantitative determination of morphine in serum by radioimmunoassay. J Pharmacol Exp Ther 1971, 178(August (2)):253-258.
    • (1971) J Pharmacol Exp Ther , vol.178 , Issue.AUGUST 2 , pp. 253-258
    • Spector, S.1
  • 16
    • 0015092883 scopus 로고
    • Specificity of the antibody receptor site to d-lysergamide: model of a physiological receptor for lysergic acid diethylamide
    • Van Vunakis H., Farrow J.T., Gjika H.B., Levine L. Specificity of the antibody receptor site to d-lysergamide: model of a physiological receptor for lysergic acid diethylamide. Proc Natl Acad Sci U S A 1971, 68(July (7)):1483-1487.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , Issue.JULY 7 , pp. 1483-1487
    • Van Vunakis, H.1    Farrow, J.T.2    Gjika, H.B.3    Levine, L.4
  • 17
    • 0015294958 scopus 로고
    • Specificities of antibodies to morphine
    • Van Vunakis H., Wasserman E., Levine L. Specificities of antibodies to morphine. J Pharmacol Exp Ther 1972, 180(February (2)):514-521.
    • (1972) J Pharmacol Exp Ther , vol.180 , Issue.FEBRUARY 2 , pp. 514-521
    • Van Vunakis, H.1    Wasserman, E.2    Levine, L.3
  • 18
    • 0015519428 scopus 로고
    • Spin immunoassay technique for determination of morphine
    • Leute R.K., Ullman E.F., Goldstein A., Herzenberg L.A. Spin immunoassay technique for determination of morphine. Nat New Biol 1972, 236(March (64)):93-94.
    • (1972) Nat New Biol , vol.236 , Issue.MARCH 64 , pp. 93-94
    • Leute, R.K.1    Ullman, E.F.2    Goldstein, A.3    Herzenberg, L.A.4
  • 19
    • 0015813792 scopus 로고
    • Nicotine and its metabolites. Radioimmunoassays for nicotine and cotinine
    • Langone J.J., Gjika H.B., Van Vunakis H. Nicotine and its metabolites. Radioimmunoassays for nicotine and cotinine. Biochemistry 1973, November (12)(24):5025-5030.
    • (1973) Biochemistry , Issue.24 NOVEMBER 12 , pp. 5025-5030
    • Langone, J.J.1    Gjika, H.B.2    Van Vunakis, H.3
  • 20
    • 0016032287 scopus 로고
    • Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse
    • Mulé S.J., Bastos M.L., Jukofsky D. Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse. Clin Chem 1974, 20(February (2)):243-248.
    • (1974) Clin Chem , vol.20 , Issue.FEBRUARY 2 , pp. 243-248
    • Mulé, S.J.1    Bastos, M.L.2    Jukofsky, D.3
  • 21
    • 0000082704 scopus 로고
    • Preparation of immunogens
    • Academic Press, New York
    • Chase M.W. Preparation of immunogens. Methods in immunology and immunochemistry 1967, vol. I:197-209. Academic Press, New York.
    • (1967) Methods in immunology and immunochemistry , vol.1 , pp. 197-209
    • Chase, M.W.1
  • 22
    • 0027213307 scopus 로고
    • Simple method for the preparation of antigen emulsions for immunization
    • Moncada C., Torres V., Israel Y. Simple method for the preparation of antigen emulsions for immunization. J Immunol Methods 1993, 162(June (1)):133-140.
    • (1993) J Immunol Methods , vol.162 , Issue.JUNE 1 , pp. 133-140
    • Moncada, C.1    Torres, V.2    Israel, Y.3
  • 23
    • 0017573773 scopus 로고
    • The immunological assay of drugs
    • Butler V.P. The immunological assay of drugs. Pharmacol Rev 1977, 29(June (2)):103-184.
    • (1977) Pharmacol Rev , vol.29 , Issue.JUNE 2 , pp. 103-184
    • Butler, V.P.1
  • 24
    • 79955475794 scopus 로고    scopus 로고
    • Applications and recent developments of multianalyte simultaneous analysis by enzyme-linked immunosorbent assays
    • Zhang H., Wang S., Fang G. Applications and recent developments of multianalyte simultaneous analysis by enzyme-linked immunosorbent assays. J Immunol Methods 2011, 368(1-2):1-23.
    • (2011) J Immunol Methods , vol.368 , Issue.1-2 , pp. 1-23
    • Zhang, H.1    Wang, S.2    Fang, G.3
  • 25
    • 0016338395 scopus 로고
    • Changes in heroin self-administration by a rhesus monkey after morphine immunisation
    • Bonese K.F., Wainer B.H., Fitch F.W., Rothberg R.M., Schuster C.R. Changes in heroin self-administration by a rhesus monkey after morphine immunisation. Nature 1974, 252(December (5485)):708-710.
    • (1974) Nature , vol.252 , Issue.DECEMBER 5485 , pp. 708-710
    • Bonese, K.F.1    Wainer, B.H.2    Fitch, F.W.3    Rothberg, R.M.4    Schuster, C.R.5
  • 26
    • 33645225168 scopus 로고    scopus 로고
    • The use of oil adjuvants in therapeutic vaccines
    • Aucouturier J., Ascarateil S., Dupuis L. The use of oil adjuvants in therapeutic vaccines. Vaccine 2006, 2(April (24 Suppl)):S2-S44.
    • (2006) Vaccine , vol.2 , Issue.APRIL 24 SUPPL , pp. S2-S44
    • Aucouturier, J.1    Ascarateil, S.2    Dupuis, L.3
  • 27
    • 77957355380 scopus 로고    scopus 로고
    • Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*2402
    • Baba T., Sato-Matsushita M., Kanamoto A., Itoh A., Oyaizu N., Inoue Y., et al. Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*2402. J Transl Med 2010, 8. 10.1186/1479-5876-8-84.
    • (2010) J Transl Med , vol.8
    • Baba, T.1    Sato-Matsushita, M.2    Kanamoto, A.3    Itoh, A.4    Oyaizu, N.5    Inoue, Y.6
  • 28
    • 18744364924 scopus 로고    scopus 로고
    • Design and selection of vaccine adjuvants: animal models and human trials
    • Alving C.R. Design and selection of vaccine adjuvants: animal models and human trials. Vaccine 2002, 3(May (20 Suppl)):S56-S64.
    • (2002) Vaccine , vol.3 , Issue.MAY 20 SUPPL , pp. S56-S64
    • Alving, C.R.1
  • 29
    • 74649084593 scopus 로고    scopus 로고
    • The ABC of clinical and experimental adjuvants--a brief overview
    • Brunner R., Jensen-Jarolim E., Pali-Schöll I. The ABC of clinical and experimental adjuvants--a brief overview. Immunol Lett 2010, 128(January (1)):29-35.
    • (2010) Immunol Lett , vol.128 , Issue.JANUARY 1 , pp. 29-35
    • Brunner, R.1    Jensen-Jarolim, E.2    Pali-Schöll, I.3
  • 30
    • 84893176616 scopus 로고    scopus 로고
    • New directions in nicotine vaccine design and use
    • Pentel P.R., Lesage M.G. New directions in nicotine vaccine design and use. Adv Pharmacol 2014, 69:553-580.
    • (2014) Adv Pharmacol , vol.69 , pp. 553-580
    • Pentel, P.R.1    Lesage, M.G.2
  • 31
    • 22544431937 scopus 로고    scopus 로고
    • A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity
    • Maurer P., Jennings G.T., Willers J., Rohner F., Lindman Y., Roubicek K., et al. A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity. Eur J Immunol 2005, 35(July (7)):2031-2040.
    • (2005) Eur J Immunol , vol.35 , Issue.JULY 7 , pp. 2031-2040
    • Maurer, P.1    Jennings, G.T.2    Willers, J.3    Rohner, F.4    Lindman, Y.5    Roubicek, K.6
  • 33
    • 84883598261 scopus 로고    scopus 로고
    • Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food
    • Rüedi-Bettschen D., Wood S.L., Gunnell M.G., West C.M., Pidaparthi R.R., Carroll F.I., et al. Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food. Vaccine 2013, 31(September (41)):4596-4602.
    • (2013) Vaccine , vol.31 , Issue.SEPTEMBER 41 , pp. 4596-4602
    • Rüedi-Bettschen, D.1    Wood, S.L.2    Gunnell, M.G.3    West, C.M.4    Pidaparthi, R.R.5    Carroll, F.I.6
  • 35
    • 0037081517 scopus 로고    scopus 로고
    • Human therapeutic cocaine vaccine: safety and immunogenicity
    • January 7-8
    • Kosten T.R., Rosen M., Bond J., Settles M., Roberts J.S., Shields J., et al. Human therapeutic cocaine vaccine: safety and immunogenicity. Vaccine 2002, 20(January (7-8)):1196-1204.
    • (2002) Vaccine , vol.20 , pp. 1196-1204
    • Kosten, T.R.1    Rosen, M.2    Bond, J.3    Settles, M.4    Roberts, J.S.5    Shields, J.6
  • 36
    • 49649104752 scopus 로고    scopus 로고
    • A vaccine against nicotine for smoking cessation: a randomized controlled trial
    • Cornuz J., Zwahlen S., Jungi W.F., Osterwalder J., Klingler K., van Melle G., et al. A vaccine against nicotine for smoking cessation: a randomized controlled trial. PLoS One 2008, 3(June (6)):e2547. 10.1371/journal.pone.0002547.
    • (2008) PLoS One , vol.3 , Issue.JUNE 6
    • Cornuz, J.1    Zwahlen, S.2    Jungi, W.F.3    Osterwalder, J.4    Klingler, K.5    van Melle, G.6
  • 37
    • 70349690285 scopus 로고    scopus 로고
    • Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial
    • Martell B.A., Orson F.M., Poling J., Mitchell E., Rossen R.D., Gardner T., et al. Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial. Arch Gen Psychiatry 2009, 66(October (10)):1116-1123.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.OCTOBER 10 , pp. 1116-1123
    • Martell, B.A.1    Orson, F.M.2    Poling, J.3    Mitchell, E.4    Rossen, R.D.5    Gardner, T.6
  • 38
    • 71349084953 scopus 로고    scopus 로고
    • Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans
    • Haney M., Gunderson E.W., Jiang H., Collins E.D., Foltin R.W. Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans. Biol Psychiatry 2010, 67(January (1)):59-65.
    • (2010) Biol Psychiatry , vol.67 , Issue.JANUARY 1 , pp. 59-65
    • Haney, M.1    Gunderson, E.W.2    Jiang, H.3    Collins, E.D.4    Foltin, R.W.5
  • 39
    • 77958498579 scopus 로고    scopus 로고
    • Safety of human therapeutic morphine vaccine employing Lohmann specific pathogen free eggs
    • Farhangi A., Akbarzadeh A., Mehrabi M.R., Chiani M., Saffari Z., Ghassemi S., et al. Safety of human therapeutic morphine vaccine employing Lohmann specific pathogen free eggs. Pak J Biol Sci 2010, 13(November (21)):1047-1051.
    • (2010) Pak J Biol Sci , vol.13 , Issue.NOVEMBER 21 , pp. 1047-1051
    • Farhangi, A.1    Akbarzadeh, A.2    Mehrabi, M.R.3    Chiani, M.4    Saffari, Z.5    Ghassemi, S.6
  • 40
    • 84875968123 scopus 로고    scopus 로고
    • Enhancing immunogenicity of a 3'aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates
    • McCluskie M.J., Pryde D.C., Gervais D.P., Stead D.R., Zhang N., Benoit M., et al. Enhancing immunogenicity of a 3'aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates. Int Immunopharmacol 2013, 16(May (1)):50-56.
    • (2013) Int Immunopharmacol , vol.16 , Issue.MAY 1 , pp. 50-56
    • McCluskie, M.J.1    Pryde, D.C.2    Gervais, D.P.3    Stead, D.R.4    Zhang, N.5    Benoit, M.6
  • 41
    • 0035114819 scopus 로고    scopus 로고
    • Generation of anti-(+)methamphetamine antibodies is not impeded by (+)methamphetamine administration during active immunization of rats
    • Byrnes-Blake K.A., Carroll F.I., Abraham P., Owens S.M. Generation of anti-(+)methamphetamine antibodies is not impeded by (+)methamphetamine administration during active immunization of rats. Int Immunopharmacol 2001, 1(February (2)):329-338.
    • (2001) Int Immunopharmacol , vol.1 , Issue.FEBRUARY 2 , pp. 329-338
    • Byrnes-Blake, K.A.1    Carroll, F.I.2    Abraham, P.3    Owens, S.M.4
  • 43
    • 33645064261 scopus 로고    scopus 로고
    • A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents
    • Anton B., Leff P. A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents. Vaccine 2006, 24(April (16)):3232-3240.
    • (2006) Vaccine , vol.24 , Issue.APRIL 16 , pp. 3232-3240
    • Anton, B.1    Leff, P.2
  • 46
    • 84871031431 scopus 로고    scopus 로고
    • Investigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance
    • Bremer P.T., Janda K.D. Investigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance. J Med Chem 2012, 55(December (23)):10776-10780.
    • (2012) J Med Chem , vol.55 , Issue.DECEMBER 23 , pp. 10776-10780
    • Bremer, P.T.1    Janda, K.D.2
  • 47
    • 84901741086 scopus 로고    scopus 로고
    • Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy
    • (in press)
    • Bremer P.T., Schlosburg J.E., Lively J.M., Janda K.D. Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy. Mol Pharmaceutics 2014, (in press).
    • (2014) Mol Pharmaceutics
    • Bremer, P.T.1    Schlosburg, J.E.2    Lively, J.M.3    Janda, K.D.4
  • 48
    • 84873905113 scopus 로고    scopus 로고
    • Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens
    • Pravetoni M., Le Naour M., Tucker A.M., Harmon T.M., Hawley T.M., Portoghese P.S., et al. Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens. J Med Chem 2013, 56(February (3)):915-923.
    • (2013) J Med Chem , vol.56 , Issue.FEBRUARY 3 , pp. 915-923
    • Pravetoni, M.1    Le Naour, M.2    Tucker, A.M.3    Harmon, T.M.4    Hawley, T.M.5    Portoghese, P.S.6
  • 49
    • 84861982138 scopus 로고    scopus 로고
    • Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats
    • Pravetoni M., Raleigh M.D., Le Naour M., Tucker A.M., Harmon T.M., Jones J.M., et al. Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats. Vaccine 2012, 30(June (31)):4617-4624.
    • (2012) Vaccine , vol.30 , Issue.JUNE 31 , pp. 4617-4624
    • Pravetoni, M.1    Raleigh, M.D.2    Le Naour, M.3    Tucker, A.M.4    Harmon, T.M.5    Jones, J.M.6
  • 50
    • 84897439342 scopus 로고    scopus 로고
    • Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse
    • Taylor J.J., Laudenbach M., Tucker A.M., Jenkins M.K., Pravetoni M. Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse. J Immunol Methods 2014, 405(March):74-86.
    • (2014) J Immunol Methods , vol.405 , Issue.MARCH , pp. 74-86
    • Taylor, J.J.1    Laudenbach, M.2    Tucker, A.M.3    Jenkins, M.K.4    Pravetoni, M.5
  • 51
    • 77950589619 scopus 로고    scopus 로고
    • A critical evaluation of a nicotine vaccine within a self-administration behavioral model
    • Moreno A.Y., Azar M.R., Warren N.A., Dickerson T.J., Koob G.F., Janda K.D. A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Mol Pharm 2010, 7(April (2)):431-441.
    • (2010) Mol Pharm , vol.7 , Issue.APRIL 2 , pp. 431-441
    • Moreno, A.Y.1    Azar, M.R.2    Warren, N.A.3    Dickerson, T.J.4    Koob, G.F.5    Janda, K.D.6
  • 52
    • 0029563411 scopus 로고
    • Suppression of psychoactive effects of cocaine by active immunization
    • Carrera M.R., Ashley J.A., Parsons L.H., Wirsching P., Koob G.F., Janda K.D. Suppression of psychoactive effects of cocaine by active immunization. Nature 1995, 378(December (6558)):727-730.
    • (1995) Nature , vol.378 , Issue.DECEMBER 6558 , pp. 727-730
    • Carrera, M.R.1    Ashley, J.A.2    Parsons, L.H.3    Wirsching, P.4    Koob, G.F.5    Janda, K.D.6
  • 53
    • 84874589023 scopus 로고    scopus 로고
    • Modulating cocaine vaccine potency through hapten fluorination
    • Cai X., Tsuchikama K., Janda K.D. Modulating cocaine vaccine potency through hapten fluorination. J Am Chem Soc 2013, 135(February (8)):2971-2974.
    • (2013) J Am Chem Soc , vol.135 , Issue.FEBRUARY 8 , pp. 2971-2974
    • Cai, X.1    Tsuchikama, K.2    Janda, K.D.3
  • 54
    • 79955399425 scopus 로고    scopus 로고
    • Impact of distinct chemical structures for the development of a methamphetamine vaccine
    • Moreno A.Y., Mayorov A.V., Janda K.D. Impact of distinct chemical structures for the development of a methamphetamine vaccine. J Am Chem Soc 2011, 133(May (17)):6587-6595.
    • (2011) J Am Chem Soc , vol.133 , Issue.MAY 17 , pp. 6587-6595
    • Moreno, A.Y.1    Mayorov, A.V.2    Janda, K.D.3
  • 55
    • 84875746967 scopus 로고    scopus 로고
    • A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats
    • Miller M.L., Moreno A.Y., Aarde S.M., Creehan K.M., Vandewater S.A., Vaillancourt B.D., et al. A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats. Biol Psychiatry 2013, 73(April (8)):721-728.
    • (2013) Biol Psychiatry , vol.73 , Issue.APRIL 8 , pp. 721-728
    • Miller, M.L.1    Moreno, A.Y.2    Aarde, S.M.3    Creehan, K.M.4    Vandewater, S.A.5    Vaillancourt, B.D.6
  • 57
    • 84896529952 scopus 로고    scopus 로고
    • Investigating hapten clustering as a strategy to enhance vaccines against drugs of abuse
    • Collins K.C., Janda K.D. Investigating hapten clustering as a strategy to enhance vaccines against drugs of abuse. Bioconjug Chem. 2014, 25(March (3)):593-600.
    • (2014) Bioconjug Chem. , vol.25 , Issue.MARCH 3 , pp. 593-600
    • Collins, K.C.1    Janda, K.D.2
  • 58
    • 0015863098 scopus 로고
    • Antibodies to morphine, barbiturates, and serotonin
    • Spector S., Berkowitz B., Flynn E.J., Peskar B. Antibodies to morphine, barbiturates, and serotonin. Pharmacol Rev 1973, 25(2):281-291.
    • (1973) Pharmacol Rev , vol.25 , Issue.2 , pp. 281-291
    • Spector, S.1    Berkowitz, B.2    Flynn, E.J.3    Peskar, B.4
  • 59
  • 60
    • 0033859862 scopus 로고    scopus 로고
    • Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain
    • Hieda Y., Keyler D.E., Ennifar S., Fattom A., Pentel P.R. Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain. Int J Immunopharmacol 2000, 22(October (10)):809-819.
    • (2000) Int J Immunopharmacol , vol.22 , Issue.OCTOBER 10 , pp. 809-819
    • Hieda, Y.1    Keyler, D.E.2    Ennifar, S.3    Fattom, A.4    Pentel, P.R.5
  • 61
    • 79953687362 scopus 로고    scopus 로고
    • Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats
    • Pravetoni M., Keyler D.E., Raleigh M.D., Harris A.C., Lesage M.G., Mattson C.K., et al. Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats. Biochem Pharmacol 2011, 81(May (9)):1164-1170.
    • (2011) Biochem Pharmacol , vol.81 , Issue.MAY 9 , pp. 1164-1170
    • Pravetoni, M.1    Keyler, D.E.2    Raleigh, M.D.3    Harris, A.C.4    Lesage, M.G.5    Mattson, C.K.6
  • 63
    • 82955247970 scopus 로고    scopus 로고
    • A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats
    • Li Q.Q., Luo Y.X., Sun C.Y., Xue Y.X., Zhu W.L., Shi H.S., et al. A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats. J Neurochem 2011, 119(December (6)):1271-1281.
    • (2011) J Neurochem , vol.119 , Issue.DECEMBER 6 , pp. 1271-1281
    • Li, Q.Q.1    Luo, Y.X.2    Sun, C.Y.3    Xue, Y.X.4    Zhu, W.L.5    Shi, H.S.6
  • 64
    • 84878417756 scopus 로고    scopus 로고
    • Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs
    • Matyas G.R., Mayorov A.V., Rice K.C., Jacobson A.E., Cheng K., Iyer M.R., et al. Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine 2013, 31(June (26)):2804-2810.
    • (2013) Vaccine , vol.31 , Issue.JUNE 26 , pp. 2804-2810
    • Matyas, G.R.1    Mayorov, A.V.2    Rice, K.C.3    Jacobson, A.E.4    Cheng, K.5    Iyer, M.R.6
  • 65
    • 84896736754 scopus 로고    scopus 로고
    • Facial recognition of heroin vaccine opiates: Type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine
    • Matyas G.R., Rice K.C., Cheng K., Li F., Antoline J.F., Iyer M.R., et al. Facial recognition of heroin vaccine opiates: Type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine 2014, 32:1473-1479.
    • (2014) Vaccine , vol.32 , pp. 1473-1479
    • Matyas, G.R.1    Rice, K.C.2    Cheng, K.3    Li, F.4    Antoline, J.F.5    Iyer, M.R.6
  • 66
    • 0037238710 scopus 로고    scopus 로고
    • Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant
    • Sanderson S.D., Cheruku S.R., Padmanilayam M.P., Vennerstrom J.L., Thiele G.M., Palmatier M.I., et al. Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvant. Int Immunopharmacol 2003, 3(January (1)):137-146.
    • (2003) Int Immunopharmacol , vol.3 , Issue.JANUARY 1 , pp. 137-146
    • Sanderson, S.D.1    Cheruku, S.R.2    Padmanilayam, M.P.3    Vennerstrom, J.L.4    Thiele, G.M.5    Palmatier, M.I.6
  • 67
    • 84922405985 scopus 로고    scopus 로고
    • accessed 11 July 2014.
    • http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003809.pdf, accessed 11 July 2014.
  • 68
    • 84870863719 scopus 로고    scopus 로고
    • Glycoconjugate vaccines
    • Pace D. Glycoconjugate vaccines. Expert Opin Biol Ther 2013, 13(January (1)):11-33.
    • (2013) Expert Opin Biol Ther , vol.13 , Issue.JANUARY 1 , pp. 11-33
    • Pace, D.1
  • 69
    • 84882267659 scopus 로고    scopus 로고
    • Carbohydrates and T cells: a sweet twosome
    • Avci F.Y., Li X., Tsuji M., Kasper D.L. Carbohydrates and T cells: a sweet twosome. Semin Immunol 2013, 25(April (2)):146-151.
    • (2013) Semin Immunol , vol.25 , Issue.APRIL 2 , pp. 146-151
    • Avci, F.Y.1    Li, X.2    Tsuji, M.3    Kasper, D.L.4
  • 70
    • 34250331531 scopus 로고    scopus 로고
    • The perfect mix: recent progress in adjuvant research
    • Guy B. The perfect mix: recent progress in adjuvant research. Nat Rev Microbiol 2007, 5(July (7)):505-517.
    • (2007) Nat Rev Microbiol , vol.5 , Issue.JULY 7 , pp. 505-517
    • Guy, B.1
  • 71
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: putting innate immunity to work
    • Coffman R.L., Sher A., Seder R.A. Vaccine adjuvants: putting innate immunity to work. Immunity 2010, 33(October (4)):492-503.
    • (2010) Immunity , vol.33 , Issue.OCTOBER 4 , pp. 492-503
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 73
    • 0027944114 scopus 로고
    • Liposomes as carriers for vaccines
    • Wassef N.M., Alving C.R., Richards R.L. Liposomes as carriers for vaccines. Immunomethods 1994, 4(June (3)):217-222.
    • (1994) Immunomethods , vol.4 , Issue.JUNE 3 , pp. 217-222
    • Wassef, N.M.1    Alving, C.R.2    Richards, R.L.3
  • 74
    • 84864924172 scopus 로고    scopus 로고
    • Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines
    • Alving C.R., Rao M., Steers N.J., Matyas G.R., Mayorov A.V. Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines. Expert Rev Vaccines 2012, 11(June (6)):733-744.
    • (2012) Expert Rev Vaccines , vol.11 , Issue.JUNE 6 , pp. 733-744
    • Alving, C.R.1    Rao, M.2    Steers, N.J.3    Matyas, G.R.4    Mayorov, A.V.5
  • 75
    • 0032706419 scopus 로고    scopus 로고
    • Oil-in-water liposomal emulsions: characterization and potential use in vaccine delivery
    • Muderhwa J.M., Matyas G.R., Spitler L.E., Alving C.R. Oil-in-water liposomal emulsions: characterization and potential use in vaccine delivery. J Pharm Sci 1999, 88(December (12)):1332-1339.
    • (1999) J Pharm Sci , vol.88 , Issue.DECEMBER 12 , pp. 1332-1339
    • Muderhwa, J.M.1    Matyas, G.R.2    Spitler, L.E.3    Alving, C.R.4
  • 76
    • 1342333037 scopus 로고    scopus 로고
    • Oil-in-water liposomal emulsions for vaccine delivery
    • Matyas G.R., Muderhwa J.M., Alving C.R. Oil-in-water liposomal emulsions for vaccine delivery. Methods Enzymol 2003, 373:34-50.
    • (2003) Methods Enzymol , vol.373 , pp. 34-50
    • Matyas, G.R.1    Muderhwa, J.M.2    Alving, C.R.3
  • 77
    • 81955160717 scopus 로고    scopus 로고
    • Immunomodulatory and physical effects of oil composition in vaccine adjuvant emulsions
    • Fox C.B., Baldwin S.L., Duthie M.S., Reed S.G., Vedvick T.S. Immunomodulatory and physical effects of oil composition in vaccine adjuvant emulsions. Vaccine 2011, 29(November (51)):9563-9572.
    • (2011) Vaccine , vol.29 , Issue.NOVEMBER 51 , pp. 9563-9572
    • Fox, C.B.1    Baldwin, S.L.2    Duthie, M.S.3    Reed, S.G.4    Vedvick, T.S.5
  • 78
    • 0004253562 scopus 로고
    • Reinhold, New York, [There is also a 3rd ed. New York: Oxford University Press; 2001]
    • Becher E. Emulsions: Theory and Practice 1965, Reinhold, New York, [There is also a 3rd ed. New York: Oxford University Press; 2001]. 2nd ed. ACS Monograph No. 162.
    • (1965) Emulsions: Theory and Practice
    • Becher, E.1
  • 80
    • 0037205207 scopus 로고    scopus 로고
    • Aluminum salts in vaccines--US perspective
    • Baylor N.W., Egan W., Richman P. Aluminum salts in vaccines--US perspective. Vaccine 2002, 20(May (Suppl 3)):S18-S23.
    • (2002) Vaccine , vol.20 , Issue.MAY SUPPL 3 , pp. S18-S23
    • Baylor, N.W.1    Egan, W.2    Richman, P.3
  • 81
    • 9244234954 scopus 로고    scopus 로고
    • Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs
    • Felnerova D., Viret J.F., Glück R., Moser C. Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs. Curr Opin Biotechnol 2004, 15(6):518-529.
    • (2004) Curr Opin Biotechnol , vol.15 , Issue.6 , pp. 518-529
    • Felnerova, D.1    Viret, J.F.2    Glück, R.3    Moser, C.4
  • 82
    • 84871578453 scopus 로고    scopus 로고
    • The history of MF59(®) adjuvant: a phoenix that arose from the ashes
    • O'Hagan D.T., Ott G.S., Nest G.V., Rappuoli R., Giudice G.D. The history of MF59(®) adjuvant: a phoenix that arose from the ashes. Expert Rev Vaccines 2013, 12(January (1)):13-30.
    • (2013) Expert Rev Vaccines , vol.12 , Issue.JANUARY 1 , pp. 13-30
    • O'Hagan, D.T.1    Ott, G.S.2    Nest, G.V.3    Rappuoli, R.4    Giudice, G.D.5
  • 83
    • 84903757911 scopus 로고    scopus 로고
    • New Th2 adjuvants for preventive and active immunotherapy of neurodegenerative proteinopathies
    • Marciani D.J. New Th2 adjuvants for preventive and active immunotherapy of neurodegenerative proteinopathies. Drug Discov Today 2014, 19(July (7)):912-920.
    • (2014) Drug Discov Today , vol.19 , Issue.JULY 7 , pp. 912-920
    • Marciani, D.J.1
  • 84
    • 84862785552 scopus 로고    scopus 로고
    • Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine
    • Sablan B.P., Kim D.J., Barzaga N.G., Chow W.C., Cho M., Ahn S.H., et al. Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine. Vaccine 2012, 30(March (16)):2689-2696.
    • (2012) Vaccine , vol.30 , Issue.MARCH 16 , pp. 2689-2696
    • Sablan, B.P.1    Kim, D.J.2    Barzaga, N.G.3    Chow, W.C.4    Cho, M.5    Ahn, S.H.6
  • 85
    • 84883031352 scopus 로고    scopus 로고
    • The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV™ review
    • Eng NF1, Bhardwaj N., Mulligan R., Diaz-Mitoma F. The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV™ review. Hum Vaccin Immunother 2013, 9(August (8)):1661-1672.
    • (2013) Hum Vaccin Immunother , vol.9 , Issue.AUGUST 8 , pp. 1661-1672
    • Eng, NF11    Bhardwaj, N.2    Mulligan, R.3    Diaz-Mitoma, F.4
  • 86
    • 84922405984 scopus 로고    scopus 로고
    • accessed 12.07.14.
    • Dynavax hepatitis B vaccine information. , accessed 12.07.14. http://www.dynavax.com/hepatitis_bv.html.
  • 87
    • 0031834957 scopus 로고    scopus 로고
    • Emulsification of liposomes with incomplete Freund's adjuvant: stability of the liposomes and the emulsion
    • Muderhwa J.M., Rothwell S.W., Alving C.R. Emulsification of liposomes with incomplete Freund's adjuvant: stability of the liposomes and the emulsion. J Liposome Res 1998, 8:183-194.
    • (1998) J Liposome Res , vol.8 , pp. 183-194
    • Muderhwa, J.M.1    Rothwell, S.W.2    Alving, C.R.3
  • 88
    • 77049125460 scopus 로고    scopus 로고
    • Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults
    • Pierce M.A., Ellis R.D., Martin L.B., Malkin E., Tierney E., Miura K., et al. Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults. Vaccine 2010, 28(March (10)):2236-2242.
    • (2010) Vaccine , vol.28 , Issue.MARCH 10 , pp. 2236-2242
    • Pierce, M.A.1    Ellis, R.D.2    Martin, L.B.3    Malkin, E.4    Tierney, E.5    Miura, K.6
  • 89
    • 0025119105 scopus 로고
    • Surface chemistry and classification of vaccine adjuvants and vehicles
    • Woodard L.F. Surface chemistry and classification of vaccine adjuvants and vehicles. Adv Biotechnol Processes 1990, 13:281-306.
    • (1990) Adv Biotechnol Processes , vol.13 , pp. 281-306
    • Woodard, L.F.1
  • 90
    • 0002689855 scopus 로고
    • Ribi adjuvants: chemistry biology and utility in vaccines for human and veterinary medicine
    • John Wiley & Sons, New York, D.E.S. Stewart-Tull (Ed.)
    • Rudbach J.A., Johnson D.A., Ulrich J.T. Ribi adjuvants: chemistry biology and utility in vaccines for human and veterinary medicine. The theory and practical application of adjuvants 1995, 287-313. John Wiley & Sons, New York. D.E.S. Stewart-Tull (Ed.).
    • (1995) The theory and practical application of adjuvants , pp. 287-313
    • Rudbach, J.A.1    Johnson, D.A.2    Ulrich, J.T.3
  • 91
    • 84922405983 scopus 로고    scopus 로고
    • accessed on 9.04.14.
    • Sigma Adjuvant System Product Information. accessed on 9.04.14. https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Datasheet/5/s6322dat.pdf.
  • 92
    • 0026600790 scopus 로고
    • Comparison of immune response potentiation and in vivo inflammatory effects of Freund's and RIBI adjuvants in mice
    • Lipman N.S., Trudel L.J., Murphy J.C., Sahali Y. Comparison of immune response potentiation and in vivo inflammatory effects of Freund's and RIBI adjuvants in mice. Lab Anim Sci 1992, 42(April (2)):193-197.
    • (1992) Lab Anim Sci , vol.42 , Issue.APRIL 2 , pp. 193-197
    • Lipman, N.S.1    Trudel, L.J.2    Murphy, J.C.3    Sahali, Y.4
  • 93
    • 84874605485 scopus 로고    scopus 로고
    • Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis
    • Miller E., Andrews N., Stellitano L., Stowe J., Winstone A.M., Shneerson J., et al. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. BMJ 2013, 346(February):f794.
    • (2013) BMJ , vol.346 , Issue.FEBRUARY , pp. f794
    • Miller, E.1    Andrews, N.2    Stellitano, L.3    Stowe, J.4    Winstone, A.M.5    Shneerson, J.6
  • 94
    • 35348968868 scopus 로고    scopus 로고
    • Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
    • Hem S.L., HogenEsch H. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev Vaccines 2007, 6(October (5)):685-698.
    • (2007) Expert Rev Vaccines , vol.6 , Issue.OCTOBER 5 , pp. 685-698
    • Hem, S.L.1    HogenEsch, H.2
  • 95
    • 34249941061 scopus 로고    scopus 로고
    • Imject® Alum is not aluminum hydroxide adjuvant or aluminum phosphate adjuvant
    • Hem S.L., Johnston C.T., HogenEsch H. Imject® Alum is not aluminum hydroxide adjuvant or aluminum phosphate adjuvant. Vaccine 2007, 25(June (27)):4985-4986.
    • (2007) Vaccine , vol.25 , Issue.JUNE 27 , pp. 4985-4986
    • Hem, S.L.1    Johnston, C.T.2    HogenEsch, H.3
  • 96
    • 84874261152 scopus 로고    scopus 로고
    • Mechanism of immunopotentiation and safety of aluminum adjuvants
    • HogenEsch H. Mechanism of immunopotentiation and safety of aluminum adjuvants. Front Immunol 2013, 3(January):406. 10.3389/fimmu.2012.00406.
    • (2013) Front Immunol , vol.3 , Issue.JANUARY , pp. 406
    • HogenEsch, H.1
  • 97
    • 82255175801 scopus 로고    scopus 로고
    • Aluminum adjuvant dose guidelines in vaccine formulation for preclinical evaluations
    • Vecchi S., Bufali S., Skibinski D.A., O'Hagan D.T., Singh M. Aluminum adjuvant dose guidelines in vaccine formulation for preclinical evaluations. J Pharm Sci 2012, 101(January (1)):17-20.
    • (2012) J Pharm Sci , vol.101 , Issue.JANUARY 1 , pp. 17-20
    • Vecchi, S.1    Bufali, S.2    Skibinski, D.A.3    O'Hagan, D.T.4    Singh, M.5
  • 98
    • 0028861047 scopus 로고
    • Characterization of the MN gp120 HIV-1 vaccine: antigen binding to alum
    • Weissburg R.P., Berman P.W., Cleland J.L., Eastman D., Farina F., Frie S., et al. Characterization of the MN gp120 HIV-1 vaccine: antigen binding to alum. Pharm Res 1995, 12(October (10)):1439-1446.
    • (1995) Pharm Res , vol.12 , Issue.OCTOBER 10 , pp. 1439-1446
    • Weissburg, R.P.1    Berman, P.W.2    Cleland, J.L.3    Eastman, D.4    Farina, F.5    Frie, S.6
  • 99
    • 44649198561 scopus 로고    scopus 로고
    • Lipid A and liposomes containing lipid A as antigens and adjuvants
    • Alving C.R., Rao M. Lipid A and liposomes containing lipid A as antigens and adjuvants. Vaccine 2008, 26(June (24)):3036-3045.
    • (2008) Vaccine , vol.26 , Issue.JUNE 24 , pp. 3036-3045
    • Alving, C.R.1    Rao, M.2
  • 100
    • 84883825445 scopus 로고    scopus 로고
    • Immunology. Sensing endotoxins from within
    • Kagan J.C. Immunology. Sensing endotoxins from within. Science 2013, 341(September (6151)):1184-1185.
    • (2013) Science , vol.341 , Issue.SEPTEMBER 6151 , pp. 1184-1185
    • Kagan, J.C.1
  • 101
    • 84883775365 scopus 로고    scopus 로고
    • Noncanonical inflammasome activation by intracellular LPS independent of TLR4
    • Kayagaki N., Wong M.T., Stowe I.B., Ramani S.R., Gonzalez L.C., Akashi-Takamura S., et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 2013, 341(September (6151)):1246-1249.
    • (2013) Science , vol.341 , Issue.SEPTEMBER 6151 , pp. 1246-1249
    • Kayagaki, N.1    Wong, M.T.2    Stowe, I.B.3    Ramani, S.R.4    Gonzalez, L.C.5    Akashi-Takamura, S.6
  • 102
    • 84883790050 scopus 로고    scopus 로고
    • Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock
    • Hagar J.A., Powell D.A., Aachoui Y., Ernst R.K., Miao E.A. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science 2013, 341(September (6151)):1250-1253.
    • (2013) Science , vol.341 , Issue.SEPTEMBER 6151 , pp. 1250-1253
    • Hagar, J.A.1    Powell, D.A.2    Aachoui, Y.3    Ernst, R.K.4    Miao, E.A.5
  • 103
    • 0024370352 scopus 로고
    • Retention of bacterial lipopolysaccharide at the site of subcutaneous injection
    • Yokochi T., Inoue Y., Yokoo J., Kimura Y., Kato N. Retention of bacterial lipopolysaccharide at the site of subcutaneous injection. Infect Immun 1989, 57(June (6)):1786-1791.
    • (1989) Infect Immun , vol.57 , Issue.JUNE 6 , pp. 1786-1791
    • Yokochi, T.1    Inoue, Y.2    Yokoo, J.3    Kimura, Y.4    Kato, N.5
  • 105
    • 84875184248 scopus 로고    scopus 로고
    • Therapeutic vaccines against tobacco addiction
    • Fahim R.E., Kessler P.D., Kalnik M.W. Therapeutic vaccines against tobacco addiction. Expert Rev Vaccines 2013, 12(March (3)):333-342.
    • (2013) Expert Rev Vaccines , vol.12 , Issue.MARCH 3 , pp. 333-342
    • Fahim, R.E.1    Kessler, P.D.2    Kalnik, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.