Efficient mRNA delivery with graphene oxide-polyethylenimine for generation of footprint-free human induced pluripotent stem cells

Journal of Controlled Release

Volumn 235, Issue , 2016, Pages 222-235

  Choi, Hye Yeon ^a   Lee, Tae Jin ^b,d   Yang, Gwang Mo ^a   Oh, Jaesur ^b   Won, Jihye ^a   Han, Jihae ^a   Jeong, Gun Jae ^b   Kim, Jongpil ^c   Kim, Jin Hoi ^a   Kim, Byung Soo ^b   Cho, Ssang Goo ^a  

^a Konkuk University   (South Korea)

^b Seoul National University   (South Korea)

^c Dongguk University   (South Korea)

^d WASHINGTON UNIVERSITY   (United States)

Author keywords

Footprint free transgene free; Gene delivery; Graphene oxide polyethylenimine complex; Human induced pluripotent stem cells; Integration free; iPSC; RNA delivery

Indexed keywords

CELL CULTURE; CELLS; CYTOLOGY; GENE EXPRESSION; GENE TRANSFER; GENES; GRAPHENE; MAGNETIC LEVITATION VEHICLES; MOLECULAR BIOLOGY; NUCLEIC ACIDS; RNA; TRANSCRIPTION;

GENE DELIVERY; HUMAN-INDUCED PLURIPOTENT STEM CELLS; IPSC; POLYETHYLENIMINES; TRANSGENE;

STEM CELLS;

GRAPHENE OXIDE; MESSENGER RNA; POLYETHYLENEIMINE; TRANSCRIPTION FACTOR; ALKALINE PHOSPHATASE; GRAPHITE; OXIDE;

ADULT; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; COMPLEX FORMATION; CONTROLLED STUDY; ECTODERM; ENDODERM; EPIGENETICS; FIBROBLAST; GENE EXPRESSION; GENE TARGETING; GERM LAYER; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; INNATE IMMUNITY; MESODERM; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RNA DEGRADATION; STEM CELL SELF-RENEWAL; SUSPENSION CELL CULTURE; ADIPOSE TISSUE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM;

ADIPOSE TISSUE; ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; CELL SURVIVAL; FIBROBLASTS; GRAPHITE; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; OXIDES; POLYETHYLENEIMINE; RNA, MESSENGER;

EID: 84973891011     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.06.007     Document Type: Article

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