-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006).
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
77956250728
-
Molecular analyses of human induced pluripotent stem cells and embryonic stem cells
-
Chin, M. H., Pellegrini, M., Plath, K. & Lowry, W. E. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell 7, 263-269 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 263-269
-
-
Chin, M.H.1
Pellegrini, M.2
Plath, K.3
Lowry, W.E.4
-
3
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
Hawkins, R. D. et al. Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 6, 479-491 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
-
4
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali, N. et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1, 55-70 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
-
5
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen, T. S. et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 454, 49-55 (2008).
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
-
6
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita, K., Ichisaka, T. & Yamanaka, S. Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317 (2007).
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
7
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig, M. et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448, 318-324 (2007).
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
-
8
-
-
69949104478
-
Adult mice generated from induced pluripotent stem cells
-
Boland, M. J. et al. Adult mice generated from induced pluripotent stem cells. Nature 461, 91-94 (2009).
-
(2009)
Nature
, vol.461
, pp. 91-94
-
-
Boland, M.J.1
-
9
-
-
67849133023
-
iPS cells can support full-term development of tetraploid blastocyst-complemented embryos
-
Kang, L., Wang, J., Zhang, Y., Kou, Z. & Gao, S. iPS cells can support full-term development of tetraploid blastocyst-complemented embryos. Cell Stem Cell 5, 135-138 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, pp. 135-138
-
-
Kang, L.1
Wang, J.2
Zhang, Y.3
Kou, Z.4
Gao, S.5
-
10
-
-
69949089630
-
iPS cells produce viable mice through tetraploid complementation
-
Zhao, X. et al. iPS cells produce viable mice through tetraploid complementation. Nature 461, 86-90 (2009).
-
(2009)
Nature
, vol.461
, pp. 86-90
-
-
Zhao, X.1
-
11
-
-
77952425747
-
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
-
Stadtfeld, M. et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 465, 175-181 (2010).
-
(2010)
Nature
, vol.465
, pp. 175-181
-
-
Stadtfeld, M.1
-
12
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J. et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920 (2007).
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
-
13
-
-
41349090105
-
Generation of human induced pluripotent stem cells from dermal fibroblasts
-
Lowry, W. E. et al. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc. Natl Acad. Sci. USA 105, 2883-2888 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 2883-2888
-
-
Lowry, W.E.1
-
14
-
-
84866310097
-
Role of mass spectrometry-based proteomics in the study of cellular reprogramming and induced pluripotent stem cells
-
Benevento, M. & Munoz, J. Role of mass spectrometry-based proteomics in the study of cellular reprogramming and induced pluripotent stem cells. Expert Rev. Proteomics 9, 379-399 (2012).
-
(2012)
Expert Rev. Proteomics
, vol.9
, pp. 379-399
-
-
Benevento, M.1
Munoz, J.2
-
15
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park, I.-H. et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141-146 (2008).
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.-H.1
-
16
-
-
41949098160
-
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
-
Hanna, J. et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133, 250-264 (2008).
-
(2008)
Cell
, vol.133
, pp. 250-264
-
-
Hanna, J.1
-
17
-
-
67049164945
-
Generation of induced pluripotent stem cells from human blood
-
Loh, Y.-H. et al. Generation of induced pluripotent stem cells from human blood. Blood 113, 5476-5479 (2009).
-
(2009)
Blood
, vol.113
, pp. 5476-5479
-
-
Loh, Y.-H.1
-
18
-
-
55049122748
-
Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression
-
Eminli, S., Utikal, J., Arnold, K., Jaenisch, R. & Hochedlinger, K. Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem Cells 26, 2467-2474 (2008).
-
(2008)
Stem Cells
, vol.26
, pp. 2467-2474
-
-
Eminli, S.1
Utikal, J.2
Arnold, K.3
Jaenisch, R.4
Hochedlinger, K.5
-
19
-
-
84875609093
-
A central role for TFIID in the pluripotent transcription circuitry
-
Pijnappel, W. W. M. P. et al. A central role for TFIID in the pluripotent transcription circuitry. Nature 495, 516-519 (2013).
-
(2013)
Nature
, vol.495
, pp. 516-519
-
-
Pijnappel, W.W.M.P.1
-
20
-
-
69349098834
-
Stem cells: The promises and perils of p53
-
Krizhanovsky, V. & Lowe, S. W. Stem cells: the promises and perils of p53. Nature 460, 1085-1086 (2009).
-
(2009)
Nature
, vol.460
, pp. 1085-1086
-
-
Krizhanovsky, V.1
Lowe, S.W.2
-
21
-
-
81055141362
-
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1
-
Wang, W. et al. Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1. Proc. Natl Acad. Sci. USA 108, 18283-18288 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 18283-18288
-
-
Wang, W.1
-
22
-
-
84885619736
-
Deterministic direct reprogramming of somatic cells to pluripotency
-
Rais, Y. et al. Deterministic direct reprogramming of somatic cells to pluripotency. Nature 502, 65-70 (2013).
-
(2013)
Nature
, vol.502
, pp. 65-70
-
-
Rais, Y.1
-
23
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
Huangfu, D. et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 26, 795-797 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
-
24
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng, B., Ng, J.-H., Heng, J.-C. D. & Ng, H.-H. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4, 301-312 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng, J.-H.2
Heng, J.-C.D.3
Ng, H.-H.4
-
25
-
-
49449096588
-
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
-
Wernig, M. et al. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat. Biotechnol. 26, 916-924 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 916-924
-
-
Wernig, M.1
-
26
-
-
59849092634
-
Transgenic mice with defined combinations of drug-inducible reprogramming factors
-
Markoulaki, S. et al. Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nat. Biotechnol. 27, 169-171 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 169-171
-
-
Markoulaki, S.1
-
27
-
-
64749083939
-
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen, K. et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770 (2009).
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
-
28
-
-
79952846468
-
Progress in understanding reprogramming to the induced pluripotent state
-
Plath, K. & Lowry, W. E. Progress in understanding reprogramming to the induced pluripotent state. Nat. Rev. Genet. 12, 253-265 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 253-265
-
-
Plath, K.1
Lowry, W.E.2
-
29
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R. et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7, 51-63 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
-
30
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani, P. et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7, 64-77 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
-
31
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanháusser, B. et al. Global quantification of mammalian gene expression control. Nature 473, 337-342 (2011).
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanháusser, B.1
-
32
-
-
84871297843
-
Next-generation proteomics: Towards an integrative view of proteome dynamics
-
Altelaar, A. F. M., Munoz, J. & Heck, A. J. R. Next-generation proteomics: towards an integrative view of proteome dynamics. Nat. Rev. Genet. 14, 35-48 (2013).
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 35-48
-
-
Altelaar, A.F.M.1
Munoz, J.2
Heck, A.J.R.3
-
33
-
-
84874232489
-
The coming age of complete, accurate, and ubiquitous proteomes
-
Mann, M., Kulak, N. A., Nagaraj, N. & Cox, J. The coming age of complete, accurate, and ubiquitous proteomes. Mol. Cell 49, 583-590 (2013).
-
(2013)
Mol. Cell
, vol.49
, pp. 583-590
-
-
Mann, M.1
Kulak, N.A.2
Nagaraj, N.3
Cox, J.4
-
34
-
-
82155179339
-
The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells
-
Munoz, J. et al. The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells. Mol. Syst. Biol. 7, 550 (2011).
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 550
-
-
Munoz, J.1
-
35
-
-
80053374337
-
Proteomic and phosphoproteomic comparison of human ES and iPS cells
-
Phanstiel, D. H. et al. Proteomic and phosphoproteomic comparison of human ES and iPS cells. Nat. Methods 8, 821-827 (2011).
-
(2011)
Nat. Methods
, vol.8
, pp. 821-827
-
-
Phanstiel, D.H.1
-
36
-
-
84871683601
-
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
-
Hansson, J. et al. Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. Cell Rep. 2, 1579-1592 (2012).
-
(2012)
Cell Rep.
, vol.2
, pp. 1579-1592
-
-
Hansson, J.1
-
37
-
-
84920743310
-
Divergent reprogramming routes lead to alternative stem cell states
-
Tonge, P. D. et al. Divergent reprogramming routes lead to alternative stem cell states. Nature doi: 10.1038/nature14047 (2014).
-
(2014)
Nature
-
-
Tonge, P.D.1
-
38
-
-
84920720484
-
Genome-wide characterization of the routes to pluripotency
-
Hussein, S. M. I. et al. Genome-wide characterization of the routes to pluripotency. Nature doi: 10.1038/nature14046 (2014).
-
(2014)
Nature
-
-
Hussein, S.M.I.1
-
39
-
-
84923055974
-
Small RNA changes en route to distinct cellular states of induced pluripotency
-
Clancy, J. L. et al. Small RNA changes en route to distinct cellular states of induced pluripotency. Nat. Commun. 5, 5522 doi:10.1038/ncomms6522 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5522
-
-
Clancy, J.L.1
-
40
-
-
84923368892
-
An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator
-
Lee, D.-S. et al. An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator. Nat. Commun. 5, 5619 doi:10.1038/ncomms6619 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5619
-
-
Lee, D.-S.1
-
41
-
-
52149097555
-
Regulatory networks define phenotypic classes of human stem cell lines
-
Muller, F. J. et al. Regulatory networks define phenotypic classes of human stem cell lines. Nature 455, 401-405 (2008).
-
(2008)
Nature
, vol.455
, pp. 401-405
-
-
Muller, F.J.1
-
42
-
-
85027958626
-
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
-
Ohi, Y. et al. Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat. Cell Biol. 13, 541-549 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 541-549
-
-
Ohi, Y.1
-
43
-
-
78650752402
-
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
-
Polo, J. M. et al. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat. Biotechnol. 28, 848-855 (2010).
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 848-855
-
-
Polo, J.M.1
-
44
-
-
84875923762
-
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming
-
Gao, Y. et al. Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell 12, 453-469 (2013).
-
(2013)
Cell Stem Cell
, vol.12
, pp. 453-469
-
-
Gao, Y.1
-
45
-
-
77949414371
-
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
-
Pasini, D. et al. JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 464, 306-310 (2010).
-
(2010)
Nature
, vol.464
, pp. 306-310
-
-
Pasini, D.1
-
46
-
-
7544230144
-
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti, G., Di Padova, M., Micales, B., Lyons, G. E. & Sartorelli, V. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev. 18, 2627-2638 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
Di Padova, M.2
Micales, B.3
Lyons, G.E.4
Sartorelli, V.5
-
47
-
-
77957243164
-
ChEA: Transcription factor regulation inferred from integrating genome-wide ChIP-X experiments
-
Lachmann, A. et al. ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments. Bioinformatics 26, 2438-2444 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 2438-2444
-
-
Lachmann, A.1
-
48
-
-
34249087361
-
Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
-
Schug, T. T., Berry, D. C., Shaw, N. S., Travis, S. N. & Noy, N. Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 129, 723-733 (2007).
-
(2007)
Cell
, vol.129
, pp. 723-733
-
-
Schug, T.T.1
Berry, D.C.2
Shaw, N.S.3
Travis, S.N.4
Noy, N.5
-
49
-
-
34147117905
-
Zfx controls the self-renewal of embryonic and hematopoietic stem cells
-
Galan-Caridad, J. M. et al. Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell 129, 345-357 (2007).
-
(2007)
Cell
, vol.129
, pp. 345-357
-
-
Galan-Caridad, J.M.1
-
50
-
-
12444345515
-
Tandem mass tags: A novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS
-
Thompson, A. et al. Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. Anal. Chem. 75, 1895-1904 (2003).
-
(2003)
Anal. Chem.
, vol.75
, pp. 1895-1904
-
-
Thompson, A.1
-
51
-
-
66349106471
-
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach
-
Gauci, S. et al. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal. Chem. 81, 4493-4501 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 4493-4501
-
-
Gauci, S.1
-
52
-
-
33847630405
-
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
-
Elias, J. E. & Gygi, S. P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4, 207-214 (2007).
-
(2007)
Nat. Methods
, vol.4
, pp. 207-214
-
-
Elias, J.E.1
Gygi, S.P.2
-
53
-
-
33747894577
-
TM4 microarray software suite
-
Saeed, A. I. et al. TM4 microarray software suite. Methods Enzymol. 411, 134-193 (2006).
-
(2006)
Methods Enzymol.
, vol.411
, pp. 134-193
-
-
Saeed, A.I.1
-
54
-
-
80051631238
-
GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data
-
Rigbolt, K. T. G., Vanselow, J. T. & Blagoev, B. GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data. Mol. Cell. Proteomics 10, O110.007450 (2011).
-
(2011)
Mol. Cell. Proteomics
, vol.10
-
-
Rigbolt, K.T.G.1
Vanselow, J.T.2
Blagoev, B.3
-
55
-
-
84855171722
-
Expression2Kinases: MRNA profiling linked to multiple upstream regulatory layers
-
Chen, E. Y. et al. Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers. Bioinformatics 28, 105-111 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 105-111
-
-
Chen, E.Y.1
-
56
-
-
79959453452
-
TVNViewer: An interactive visualization tool for exploring networks that change over time or space
-
Curtis, R. E., Yuen, A., Song, L., Goyal, A. & Xing, E. P. TVNViewer: an interactive visualization tool for exploring networks that change over time or space. Bioinformatics 27, 1880-1881 (2011).
-
(2011)
Bioinformatics
, vol.27
, pp. 1880-1881
-
-
Curtis, R.E.1
Yuen, A.2
Song, L.3
Goyal, A.4
Xing, E.P.5
|