-
1
-
-
0028088152
-
The alphaviruses: Gene expression, replication, and evolution
-
Strauss, J. H. and Strauss, E. G. (1994) The alphaviruses: gene expression, replication, and evolution Microbiol. Rev. 58, 491-562
-
(1994)
Microbiol. Rev.
, vol.58
, pp. 491-562
-
-
Strauss, J.H.1
Strauss, E.G.2
-
2
-
-
65349143276
-
Experimental infection of potential reservoir hosts with Venezuelan equine encephalitis virus, Mexico
-
Deardorff, E. R., Forrester, N. L., Travassos-da-Rosa, A. P., Estrada-Franco, J. G., Navarro-Lopez, R., Tesh, R. B., and Weaver, S. C. (2009) Experimental infection of potential reservoir hosts with Venezuelan equine encephalitis virus, Mexico Emerging Infect. Dis. 15, 519-525 10.3201/eid1504.081008
-
(2009)
Emerging Infect. Dis.
, vol.15
, pp. 519-525
-
-
Deardorff, E.R.1
Forrester, N.L.2
Travassos-Da-Rosa, A.P.3
Estrada-Franco, J.G.4
Navarro-Lopez, R.5
Tesh, R.B.6
Weaver, S.C.7
-
3
-
-
73949156664
-
Encephalitic alphaviruses
-
Zacks, M. A. and Paessler, S. (2010) Encephalitic alphaviruses Vet. Microbiol. 140, 281-286 10.1016/j.vetmic.2009.08.023
-
(2010)
Vet. Microbiol.
, vol.140
, pp. 281-286
-
-
Zacks, M.A.1
Paessler, S.2
-
4
-
-
80055010633
-
The role of the blood-brain barrier during Venezuelan equine encephalitis virus infection
-
Schafer, A., Brooke, C. B., Whitmore, A. C., and Johnston, R. E. (2011) The role of the blood-brain barrier during Venezuelan equine encephalitis virus infection J. Virol. 85, 10682-10690 10.1128/JVI.05032-11
-
(2011)
J. Virol.
, vol.85
, pp. 10682-10690
-
-
Schafer, A.1
Brooke, C.B.2
Whitmore, A.C.3
Johnston, R.E.4
-
6
-
-
0030951262
-
Clinical and neuroradiographic manifestations of eastern equine encephalitis
-
Deresiewicz, R. L., Thaler, S. J., Hsu, L., and Zamani, A. A. (1997) Clinical and neuroradiographic manifestations of eastern equine encephalitis N. Engl. J. Med. 336, 1867-1874 10.1056/NEJM199706263362604
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1867-1874
-
-
Deresiewicz, R.L.1
Thaler, S.J.2
Hsu, L.3
Zamani, A.A.4
-
8
-
-
84863478516
-
Arthritogenic alphaviruses - An overview
-
Suhrbier, A., Jaffar-Bandjee, M. C., and Gasque, P. (2012) Arthritogenic alphaviruses - an overview Nat. Rev. Rheumatol. 8, 420-429 10.1038/nrrheum.2012.64
-
(2012)
Nat. Rev. Rheumatol.
, vol.8
, pp. 420-429
-
-
Suhrbier, A.1
Jaffar-Bandjee, M.C.2
Gasque, P.3
-
9
-
-
52049124527
-
Host responses to alphavirus infection
-
Ryman, K. D. and Klimstra, W. B. (2008) Host responses to alphavirus infection Immunol. Rev. 225, 27-45 10.1111/j.1600-065X.2008.00670.x
-
(2008)
Immunol. Rev.
, vol.225
, pp. 27-45
-
-
Ryman, K.D.1
Klimstra, W.B.2
-
10
-
-
77958185959
-
Alphavirus Encephalitides
-
(Dembek, Z. F. Ed.) pp, Office of the Surgeon General, Falls Church, VA
-
Steele, K. E., Reed, D., Glass, P. J., Hart, M. K., Ludwig, G. V., Pratt, W. D., Parker, M. D., and Smith, J. F. (2007) Alphavirus Encephalitides. In Medical Aspects of Biological Warfare (Dembek, Z. F., Ed.) pp 241-270, Office of the Surgeon General, Falls Church, VA.
-
(2007)
Medical Aspects of Biological Warfare
, pp. 241-270
-
-
Steele, K.E.1
Reed, D.2
Glass, P.J.3
Hart, M.K.4
Ludwig, G.V.5
Pratt, W.D.6
Parker, M.D.7
Smith, J.F.8
-
11
-
-
0014196464
-
Arbovirus infections of laboratory workers. Extent of problem emphasizes the need for more effective measures to reduce hazards
-
Hanson, R. P., Sulkin, S. E., Buescher, E. L., Hammon, W. M., MCKINNEY, R. W., and Work, T. H. (1967) Arbovirus infections of laboratory workers. Extent of problem emphasizes the need for more effective measures to reduce hazards Science 158, 1283-1286 10.1126/science.158.3806.1283
-
(1967)
Science
, vol.158
, pp. 1283-1286
-
-
Hanson, R.P.1
Sulkin, S.E.2
Buescher, E.L.3
Hammon, W.M.4
McKinney, R.W.5
Work, T.H.6
-
12
-
-
0015108970
-
Effect of relative humidity and temperature on airborne Venezuelan equine encephalitis virus
-
Ehrlich, R. and Miller, S. (1971) Effect of relative humidity and temperature on airborne Venezuelan equine encephalitis virus Appl. Microbiol. 22, 194-199
-
(1971)
Appl. Microbiol.
, vol.22
, pp. 194-199
-
-
Ehrlich, R.1
Miller, S.2
-
13
-
-
78649231543
-
REVIEW PAPER: Pathology of animal models of alphavirus encephalitis
-
Steele, K. E. and Twenhafel, N. A. (2010) REVIEW PAPER: pathology of animal models of alphavirus encephalitis Vet. Pathol. 47, 790-805 10.1177/0300985810372508
-
(2010)
Vet. Pathol.
, vol.47
, pp. 790-805
-
-
Steele, K.E.1
Twenhafel, N.A.2
-
14
-
-
0026366078
-
Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice
-
Ryzhikov, A. B., Tkacheva, N. V., Sergeev, A. N., and Ryabchikova, E. I. (1991) Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice Biomed. Sci. 2, 607-614
-
(1991)
Biomed. Sci.
, vol.2
, pp. 607-614
-
-
Ryzhikov, A.B.1
Tkacheva, N.V.2
Sergeev, A.N.3
Ryabchikova, E.I.4
-
15
-
-
0029960102
-
Long-term duration of detectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine
-
Pittman, P. R., Makuch, R. S., Mangiafico, J. A., Cannon, T. L., Gibbs, P. H., and Peters, C. J. (1996) Long-term duration of detectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine Vaccine 14, 337-343 10.1016/0264-410X(95)00168-Z
-
(1996)
Vaccine
, vol.14
, pp. 337-343
-
-
Pittman, P.R.1
Makuch, R.S.2
Mangiafico, J.A.3
Cannon, T.L.4
Gibbs, P.H.5
Peters, C.J.6
-
16
-
-
0015964840
-
Inactivated Venezuelan equine encephalomyelitis vaccine prepared from attenuated (TC-83 strain) virus
-
Cole, F. E., Jr., May, S. W., and Eddy, G. A. (1974) Inactivated Venezuelan equine encephalomyelitis vaccine prepared from attenuated (TC-83 strain) virus Appl. Microbiol. 27, 150-153
-
(1974)
Appl. Microbiol.
, vol.27
, pp. 150-153
-
-
Cole, Jr.F.E.1
May, S.W.2
Eddy, G.A.3
-
17
-
-
0021318792
-
Protective efficacies of live attenuated and formaldehyde-inactivated Venezuelan equine encephalitis virus vaccines against aerosol challenge in hamsters
-
Jahrling, P. B. and Stephenson, E. H. (1984) Protective efficacies of live attenuated and formaldehyde-inactivated Venezuelan equine encephalitis virus vaccines against aerosol challenge in hamsters J. Clin. Microbiol. 19, 429-431
-
(1984)
J. Clin. Microbiol.
, vol.19
, pp. 429-431
-
-
Jahrling, P.B.1
Stephenson, E.H.2
-
18
-
-
84903458261
-
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2
-
Chung, D. H., Jonsson, C. B., Tower, N. A., Chu, Y. K., Sahin, E., Golden, J. E., Noah, J. W., Schroeder, C. E., Sotsky, J. B., Sosa, M. I., Cramer, D. E., McKellip, S. N., Rasmussen, L., White, E. L., Schmaljohn, C. S., Julander, J. G., Smith, J. M., Filone, C. M., Connor, J. H., Sakurai, Y., and Davey, R. A. (2014) Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2 PLoS Pathog. 10, e1004213 10.1371/journal.ppat.1004213
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1004213
-
-
Chung, D.H.1
Jonsson, C.B.2
Tower, N.A.3
Chu, Y.K.4
Sahin, E.5
Golden, J.E.6
Noah, J.W.7
Schroeder, C.E.8
Sotsky, J.B.9
Sosa, M.I.10
Cramer, D.E.11
McKellip, S.N.12
Rasmussen, L.13
White, E.L.14
Schmaljohn, C.S.15
Julander, J.G.16
Smith, J.M.17
Filone, C.M.18
Connor, J.H.19
Sakurai, Y.20
Davey, R.A.21
more..
-
19
-
-
84859369193
-
Modulation of GSK-3beta activity in Venezuelan equine encephalitis virus infection
-
Kehn-Hall, K., Narayanan, A., Lundberg, L., Sampey, G., Pinkham, C., Guendel, I., Van Duyne, R., Senina, S., Schultz, K. L., Stavale, E., Aman, M. J., Bailey, C., and Kashanchi, F. (2012) Modulation of GSK-3beta activity in Venezuelan equine encephalitis virus infection PLoS One 7, e34761 10.1371/journal.pone.0034761
-
(2012)
PLoS One
, vol.7
, pp. e34761
-
-
Kehn-Hall, K.1
Narayanan, A.2
Lundberg, L.3
Sampey, G.4
Pinkham, C.5
Guendel, I.6
Van Duyne, R.7
Senina, S.8
Schultz, K.L.9
Stavale, E.10
Aman, M.J.11
Bailey, C.12
Kashanchi, F.13
-
20
-
-
56349132624
-
Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine
-
Julander, J. G., Bowen, R. A., Rao, J. R., Day, C., Shafer, K., Smee, D. F., Morrey, J. D., and Chu, C. K. (2008) Treatment of Venezuelan equine encephalitis virus infection with (-)-carbodine Antiviral Res. 80, 309-315 10.1016/j.antiviral.2008.07.002
-
(2008)
Antiviral Res.
, vol.80
, pp. 309-315
-
-
Julander, J.G.1
Bowen, R.A.2
Rao, J.R.3
Day, C.4
Shafer, K.5
Smee, D.F.6
Morrey, J.D.7
Chu, C.K.8
-
21
-
-
0024315805
-
Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein
-
Ding, M. X. and Schlesinger, M. J. (1989) Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein Virology 171, 280-284 10.1016/0042-6822(89)90539-4
-
(1989)
Virology
, vol.171
, pp. 280-284
-
-
Ding, M.X.1
Schlesinger, M.J.2
-
22
-
-
0024421374
-
Processing the nonstructural polyproteins of sindbis virus: Nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans
-
Hardy, W. R. and Strauss, J. H. (1989) Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans J. Virol. 63, 4653-4664
-
(1989)
J. Virol.
, vol.63
, pp. 4653-4664
-
-
Hardy, W.R.1
Strauss, J.H.2
-
23
-
-
0142211312
-
Regulation of the sequential processing of Semliki Forest virus replicase polyprotein
-
Vasiljeva, L., Merits, A., Golubtsov, A., Sizemskaja, V., Kaariainen, L., and Ahola, T. (2003) Regulation of the sequential processing of Semliki Forest virus replicase polyprotein J. Biol. Chem. 278, 41636-41645 10.1074/jbc.M307481200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41636-41645
-
-
Vasiljeva, L.1
Merits, A.2
Golubtsov, A.3
Sizemskaja, V.4
Kaariainen, L.5
Ahola, T.6
-
24
-
-
33744937066
-
Sindbis virus nonstructural protein nsP2 is cytotoxic and inhibits cellular transcription
-
Garmashova, N., Gorchakov, R., Frolova, E., and Frolov, I. (2006) Sindbis virus nonstructural protein nsP2 is cytotoxic and inhibits cellular transcription J. Virol. 80, 5686-5696 10.1128/JVI.02739-05
-
(2006)
J. Virol.
, vol.80
, pp. 5686-5696
-
-
Garmashova, N.1
Gorchakov, R.2
Frolova, E.3
Frolov, I.4
-
25
-
-
33847199327
-
The Old World and New World alphaviruses use different virus-specific proteins for induction of transcriptional shutoff
-
Garmashova, N., Gorchakov, R., Volkova, E., Paessler, S., Frolova, E., and Frolov, I. (2007) The Old World and New World alphaviruses use different virus-specific proteins for induction of transcriptional shutoff J. Virol. 81, 2472-2484 10.1128/JVI.02073-06
-
(2007)
J. Virol.
, vol.81
, pp. 2472-2484
-
-
Garmashova, N.1
Gorchakov, R.2
Volkova, E.3
Paessler, S.4
Frolova, E.5
Frolov, I.6
-
26
-
-
47749118026
-
Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection
-
Mayuri, Geders, T. W., Smith, J. L., and Kuhn, R. J. (2008) Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection J. Virol. 82, 7284-7297 10.1128/JVI.00224-08
-
(2008)
J. Virol.
, vol.82
, pp. 7284-7297
-
-
Mayuri1
Geders, T.W.2
Smith, J.L.3
Kuhn, R.J.4
-
27
-
-
19944373420
-
Noncytopathic replication of Venezuelan equine encephalitis virus and eastern equine encephalitis virus replicons in Mammalian cells
-
Petrakova, O., Volkova, E., Gorchakov, R., Paessler, S., Kinney, R. M., and Frolov, I. (2005) Noncytopathic replication of Venezuelan equine encephalitis virus and eastern equine encephalitis virus replicons in Mammalian cells J. Virol. 79, 7597-7608 10.1128/JVI.79.12.7597-7608.2005
-
(2005)
J. Virol.
, vol.79
, pp. 7597-7608
-
-
Petrakova, O.1
Volkova, E.2
Gorchakov, R.3
Paessler, S.4
Kinney, R.M.5
Frolov, I.6
-
28
-
-
34648836389
-
Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2
-
Montgomery, S. A. and Johnston, R. E. (2007) Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2 J. Virol. 81, 10268-10279 10.1128/JVI.00371-07
-
(2007)
J. Virol.
, vol.81
, pp. 10268-10279
-
-
Montgomery, S.A.1
Johnston, R.E.2
-
29
-
-
80051752880
-
Deubiquitination activity associated with hepatitis e virus putative papain-like cysteine protease
-
Karpe, Y. A. and Lole, K. S. (2011) Deubiquitination activity associated with hepatitis E virus putative papain-like cysteine protease J. Gen. Virol. 92, 2088-2092 10.1099/vir.0.033738-0
-
(2011)
J. Gen. Virol.
, vol.92
, pp. 2088-2092
-
-
Karpe, Y.A.1
Lole, K.S.2
-
30
-
-
33748304343
-
The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease
-
Russo, A. T., White, M. A., and Watowich, S. J. (2006) The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease Structure 14, 1449-1458 10.1016/j.str.2006.07.010
-
(2006)
Structure
, vol.14
, pp. 1449-1458
-
-
Russo, A.T.1
White, M.A.2
Watowich, S.J.3
-
31
-
-
85035317552
-
-
Cheung, J., Franklin, M., Mancia, F., Rudolph, M., Cassidy, M., Gary, E., Burshteyn, F., and Love, J. (2011) Structure of the Chikungunya virus nsP2 protease.
-
(2011)
Structure of the Chikungunya Virus nsP2 Protease.
-
-
Cheung, J.1
Franklin, M.2
Mancia, F.3
Rudolph, M.4
Cassidy, M.5
Gary, E.6
Burshteyn, F.7
Love, J.8
-
32
-
-
77955773469
-
Structural basis for substrate specificity of alphavirus nsP2 proteases
-
Russo, A. T., Malmstrom, R. D., White, M. A., and Watowich, S. J. (2010) Structural basis for substrate specificity of alphavirus nsP2 proteases J. Mol. Graphics Modell. 29, 46-53 10.1016/j.jmgm.2010.04.005
-
(2010)
J. Mol. Graphics Modell.
, vol.29
, pp. 46-53
-
-
Russo, A.T.1
Malmstrom, R.D.2
White, M.A.3
Watowich, S.J.4
-
33
-
-
33646579179
-
An expression vector tailored for large-scale, high-throughput purification of recombinant proteins
-
Donnelly, M. I., Zhou, M., Millard, C. S., Clancy, S., Stols, L., Eschenfeldt, W. H., Collart, F. R., and Joachimiak, A. (2006) An expression vector tailored for large-scale, high-throughput purification of recombinant proteins Protein Expression Purif. 47, 446-454 10.1016/j.pep.2005.12.011
-
(2006)
Protein Expression Purif.
, vol.47
, pp. 446-454
-
-
Donnelly, M.I.1
Zhou, M.2
Millard, C.S.3
Clancy, S.4
Stols, L.5
Eschenfeldt, W.H.6
Collart, F.R.7
Joachimiak, A.8
-
34
-
-
4644237840
-
Three-dimensional solution structure of the cytoplasmic B domain of the mannitol transporter IImannitol of the Escherichia coli phosphotransferase system
-
Legler, P. M., Cai, M., Peterkofsky, A., and Clore, G. M. (2004) Three-dimensional solution structure of the cytoplasmic B domain of the mannitol transporter IImannitol of the Escherichia coli phosphotransferase system J. Biol. Chem. 279, 39115-39121 10.1074/jbc.M406764200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39115-39121
-
-
Legler, P.M.1
Cai, M.2
Peterkofsky, A.3
Clore, G.M.4
-
35
-
-
0011962568
-
Thioredoxin as a fusion partner for production of soluble recombinant proteins in Escherichia coli
-
LaVallie, E. R., Lu, Z., Diblasio-Smith, E. A., Collins-Racie, L. A., and McCoy, J. M. (2000) Thioredoxin as a fusion partner for production of soluble recombinant proteins in Escherichia coli Methods Enzymol. 326, 322-340 10.1016/S0076-6879(00)26063-1
-
(2000)
Methods Enzymol.
, vol.326
, pp. 322-340
-
-
LaVallie, E.R.1
Lu, Z.2
DiBlasio-Smith, E.A.3
Collins-Racie, L.A.4
McCoy, J.M.5
-
36
-
-
0037208812
-
Thioredoxin and related proteins as multifunctional fusion tags for soluble expression in E coli
-
LaVallie, E. R., DiBlasio-Smith, E. A., Collins-Racie, L. A., Lu, Z., and McCoy, J. M. (2002) Thioredoxin and related proteins as multifunctional fusion tags for soluble expression in E. coli Methods Mol. Biol. 205, 119-140 10.1385/1-59259-301-1:119
-
(2002)
Methods Mol. Biol.
, vol.205
, pp. 119-140
-
-
LaVallie, E.R.1
DiBlasio-Smith, E.A.2
Collins-Racie, L.A.3
Lu, Z.4
McCoy, J.M.5
-
37
-
-
6944237312
-
Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells
-
Dong, M., Tepp, W. H., Johnson, E. A., and Chapman, E. R. (2004) Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells Proc. Natl. Acad. Sci. U. S. A. 101, 14701-14706 10.1073/pnas.0404107101
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 14701-14706
-
-
Dong, M.1
Tepp, W.H.2
Johnson, E.A.3
Chapman, E.R.4
-
38
-
-
79952455057
-
Detection of six serotypes of botulinum neurotoxin using fluorogenic reporters
-
Ruge, D. R., Dunning, F. M., Piazza, T. M., Molles, B. E., Adler, M., Zeytin, F. N., and Tucker, W. C. (2011) Detection of six serotypes of botulinum neurotoxin using fluorogenic reporters Anal. Biochem. 411, 200-209 10.1016/j.ab.2011.01.002
-
(2011)
Anal. Biochem.
, vol.411
, pp. 200-209
-
-
Ruge, D.R.1
Dunning, F.M.2
Piazza, T.M.3
Molles, B.E.4
Adler, M.5
Zeytin, F.N.6
Tucker, W.C.7
-
39
-
-
0029814495
-
Activity of purified hepatitis C virus protease NS3 on peptide substrates
-
Steinkuhler, C., Urbani, A., Tomei, L., Biasiol, G., Sardana, M., Bianchi, E., Pessi, A., and De, F. R. (1996) Activity of purified hepatitis C virus protease NS3 on peptide substrates J. Virol. 70, 6694-6700
-
(1996)
J. Virol.
, vol.70
, pp. 6694-6700
-
-
Steinkuhler, C.1
Urbani, A.2
Tomei, L.3
Biasiol, G.4
Sardana, M.5
Bianchi, E.6
Pessi, A.7
De, F.R.8
-
40
-
-
73649151319
-
Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase
-
Kitz, R. and Wilson, I. B. (1962) Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase J. Biol. Chem. 237, 3245-3249
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 3245-3249
-
-
Kitz, R.1
Wilson, I.B.2
-
41
-
-
84862804741
-
Reducing agents affect inhibitory activities of compounds: Results from multiple drug targets
-
Lee, H., Torres, J., Truong, L., Chaudhuri, R., Mittal, A., and Johnson, M. E. (2012) Reducing agents affect inhibitory activities of compounds: results from multiple drug targets Anal. Biochem. 423, 46-53 10.1016/j.ab.2012.01.006
-
(2012)
Anal. Biochem.
, vol.423
, pp. 46-53
-
-
Lee, H.1
Torres, J.2
Truong, L.3
Chaudhuri, R.4
Mittal, A.5
Johnson, M.E.6
-
42
-
-
0035788101
-
Implementation of molecular replacement in AMoRe
-
Navaza, J. (2001) Implementation of molecular replacement in AMoRe Acta Crystallogr., Sect. D: Biol. Crystallogr. 57, 1367-1372 10.1107/S0907444901012422
-
(2001)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.57
, pp. 1367-1372
-
-
Navaza, J.1
-
44
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G., and Cowtan, K. (2010) Features and development of Coot Acta Crystallogr., Sect. D: Biol. Crystallogr. 66, 486-501 10.1107/S0907444910007493
-
(2010)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
45
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination Acta Crystallogr., Sect. D: Biol. Crystallogr. 54, 905-921 10.1107/S0907444998003254
-
(1998)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
Read, R.J.11
Rice, L.M.12
Simonson, T.13
Warren, G.L.14
-
46
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project Number 4
-
Collaborative Computational Project Number 4 (1994) The CCP4 suite: programs for protein crystallography Acta Crystallogr., Sect. D: Biol. Crystallogr. 50, 760-763 10.1107/S0907444994003112
-
(1994)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.50
, pp. 760-763
-
-
-
47
-
-
84880014221
-
Validation of a cell-based ELISA as a screening tool identifying anti-alphavirus small-molecule inhibitors
-
Spurgers, K. B., Hurt, C. R., Cohen, J. W., Eccelston, L. T., Lind, C. M., Lingappa, V. R., and Glass, P. J. (2013) Validation of a cell-based ELISA as a screening tool identifying anti-alphavirus small-molecule inhibitors J. Virol. Methods 193, 226-231 10.1016/j.jviromet.2013.06.007
-
(2013)
J. Virol. Methods
, vol.193
, pp. 226-231
-
-
Spurgers, K.B.1
Hurt, C.R.2
Cohen, J.W.3
Eccelston, L.T.4
Lind, C.M.5
Lingappa, V.R.6
Glass, P.J.7
-
48
-
-
70349932423
-
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
-
Morris, G. M., Huey, R., Lindstrom, W., Sanner, M. F., Belew, R. K., Goodsell, D. S., and Olson, A. J. (2009) AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility J. Comput. Chem. 30, 2785-2791 10.1002/jcc.21256
-
(2009)
J. Comput. Chem.
, vol.30
, pp. 2785-2791
-
-
Morris, G.M.1
Huey, R.2
Lindstrom, W.3
Sanner, M.F.4
Belew, R.K.5
Goodsell, D.S.6
Olson, A.J.7
-
49
-
-
34848874022
-
Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection
-
Paessler, S., Yun, N. E., Judy, B. M., Dziuba, N., Zacks, M. A., Grund, A. H., Frolov, I., Campbell, G. A., Weaver, S. C., and Estes, D. M. (2007) Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection Virology 367, 307-323 10.1016/j.virol.2007.05.041
-
(2007)
Virology
, vol.367
, pp. 307-323
-
-
Paessler, S.1
Yun, N.E.2
Judy, B.M.3
Dziuba, N.4
Zacks, M.A.5
Grund, A.H.6
Frolov, I.7
Campbell, G.A.8
Weaver, S.C.9
Estes, D.M.10
-
50
-
-
0026691398
-
Ester and amide derivatives of E64c as inhibitors of platelet calpains
-
Huang, Z., McGowan, E. B., and Detwiler, T. C. (1992) Ester and amide derivatives of E64c as inhibitors of platelet calpains J. Med. Chem. 35, 2048-2054 10.1021/jm00089a015
-
(1992)
J. Med. Chem.
, vol.35
, pp. 2048-2054
-
-
Huang, Z.1
McGowan, E.B.2
Detwiler, T.C.3
-
51
-
-
0022997931
-
In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64
-
Tamai, M., Matsumoto, K., Omura, S., Koyama, I., Ozawa, Y., and Hanada, K. (1986) In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64 J. Pharmacobio-Dyn. 9, 672-677 10.1248/bpb1978.9.672
-
(1986)
J. Pharmacobio-Dyn.
, vol.9
, pp. 672-677
-
-
Tamai, M.1
Matsumoto, K.2
Omura, S.3
Koyama, I.4
Ozawa, Y.5
Hanada, K.6
-
52
-
-
77955975893
-
Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimers disease
-
Hook, V., Hook, G., and Kindy, M. (2010) Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimers disease Biol. Chem. 391, 861-872 10.1515/bc.2010.110
-
(2010)
Biol. Chem.
, vol.391
, pp. 861-872
-
-
Hook, V.1
Hook, G.2
Kindy, M.3
-
53
-
-
0033037118
-
Structural basis of inhibition of cysteine proteases by E-64 and its derivatives
-
Matsumoto, K., Mizoue, K., Kitamura, K., Tse, W. C., Huber, C. P., and Ishida, T. (1999) Structural basis of inhibition of cysteine proteases by E-64 and its derivatives Biopolymers 51, 99-107 10.1002/(SICI)1097-0282(1999)51:1<99::AID-BIP11>3.0.CO;2-R
-
(1999)
Biopolymers
, vol.51
, pp. 99-107
-
-
Matsumoto, K.1
Mizoue, K.2
Kitamura, K.3
Tse, W.C.4
Huber, C.P.5
Ishida, T.6
-
54
-
-
0037014129
-
Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: Crystal structure of cathepsin B-E64c complex
-
Yamamoto, A., Tomoo, K., Matsugi, K., Hara, T., In, Y., Murata, M., Kitamura, K., and Ishida, T. (2002) Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol. 1597, 244-251 10.1016/S0167-4838(02)00284-4
-
(2002)
Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol.
, vol.1597
, pp. 244-251
-
-
Yamamoto, A.1
Tomoo, K.2
Matsugi, K.3
Hara, T.4
In, Y.5
Murata, M.6
Kitamura, K.7
Ishida, T.8
-
55
-
-
0023874705
-
Cathepsin L - A latent proteinase in Guinea pig sperm
-
McDonald, J. K. and Kadkhodayan, S. (1988) Cathepsin L - a latent proteinase in guinea pig sperm Biochem. Biophys. Res. Commun. 151, 827-835 10.1016/S0006-291X(88)80356-5
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.151
, pp. 827-835
-
-
McDonald, J.K.1
Kadkhodayan, S.2
-
56
-
-
0019486009
-
Effects of cathepsin B, H, and D in pectoral muscle of dystrophic chickens (line 413) of in vivo administration of E-64-c (N-[N-(L-3-transcarboxyoxirane-2-carbonyl)-L-leucyl]-3-methyl-butylamine
-
Noda, T., Isogai, K., Katunuma, N., Tarumoto, Y., and Ohzeki, M. (1981) Effects of cathepsin B, H, and D in pectoral muscle of dystrophic chickens (line 413) of in vivo administration of E-64-c (N-[N-(L-3-transcarboxyoxirane-2-carbonyl)-L-leucyl]-3-methyl-butylamine J. Biochem. 90, 893-896
-
(1981)
J. Biochem.
, vol.90
, pp. 893-896
-
-
Noda, T.1
Isogai, K.2
Katunuma, N.3
Tarumoto, Y.4
Ohzeki, M.5
-
57
-
-
73649151319
-
Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase
-
Kitz, R. and Wilson, I. B. (1962) Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase J. Biol. Chem. 237, 3245-3249
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 3245-3249
-
-
Kitz, R.1
Wilson, I.B.2
-
58
-
-
0026353352
-
Refined x-ray structure of papain.E-64-c complex at 2.1-A resolution
-
Yamamoto, D., Matsumoto, K., Ohishi, H., Ishida, T., Inoue, M., Kitamura, K., and Mizuno, H. (1991) Refined x-ray structure of papain.E-64-c complex at 2.1-A resolution J. Biol. Chem. 266, 14771-14777
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 14771-14777
-
-
Yamamoto, D.1
Matsumoto, K.2
Ohishi, H.3
Ishida, T.4
Inoue, M.5
Kitamura, K.6
Mizuno, H.7
-
59
-
-
0028674466
-
Catalytic mechanism in papain family of cysteine peptidases
-
Storer, A. C. and Menard, R. (1994) Catalytic mechanism in papain family of cysteine peptidases Methods Enzymol. 244, 486-500 10.1016/0076-6879(94)44035-2
-
(1994)
Methods Enzymol.
, vol.244
, pp. 486-500
-
-
Storer, A.C.1
Menard, R.2
-
60
-
-
84867391808
-
Structural and functional insights into alphavirus polyprotein processing and pathogenesis
-
Shin, G., Yost, S. A., Miller, M. T., Elrod, E. J., Grakoui, A., and Marcotrigiano, J. (2012) Structural and functional insights into alphavirus polyprotein processing and pathogenesis Proc. Natl. Acad. Sci. U. S. A. 109, 16534-16539 10.1073/pnas.1210418109
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 16534-16539
-
-
Shin, G.1
Yost, S.A.2
Miller, M.T.3
Elrod, E.J.4
Grakoui, A.5
Marcotrigiano, J.6
-
61
-
-
0032924734
-
Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells
-
Frolov, I., Agapov, E., Hoffman, T. A., Jr., Pragai, B. M., Lippa, M., Schlesinger, S., and Rice, C. M. (1999) Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells J. Virol. 73, 3854-3865
-
(1999)
J. Virol.
, vol.73
, pp. 3854-3865
-
-
Frolov, I.1
Agapov, E.2
Hoffman, Jr.T.A.3
Pragai, B.M.4
Lippa, M.5
Schlesinger, S.6
Rice, C.M.7
-
62
-
-
57649089398
-
Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphaviruses
-
Zhang, D., Tozser, J., and Waugh, D. S. (2009) Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphaviruses Protein Expression Purif. 64, 89-97 10.1016/j.pep.2008.10.013
-
(2009)
Protein Expression Purif.
, vol.64
, pp. 89-97
-
-
Zhang, D.1
Tozser, J.2
Waugh, D.S.3
-
65
-
-
84904345425
-
Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features
-
Lei, J., Mesters, J. R., Drosten, C., Anemuller, S., Ma, Q., and Hilgenfeld, R. (2014) Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features Antiviral Res. 109, 72-82 10.1016/j.antiviral.2014.06.011
-
(2014)
Antiviral Res.
, vol.109
, pp. 72-82
-
-
Lei, J.1
Mesters, J.R.2
Drosten, C.3
Anemuller, S.4
Ma, Q.5
Hilgenfeld, R.6
-
66
-
-
84901670584
-
Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease
-
Ratia, K., Kilianski, A., Baez-Santos, Y. M., Baker, S. C., and Mesecar, A. (2014) Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease PLoS Pathog. 10, e1004113 10.1371/journal.ppat.1004113
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1004113
-
-
Ratia, K.1
Kilianski, A.2
Baez-Santos, Y.M.3
Baker, S.C.4
Mesecar, A.5
-
67
-
-
33645822092
-
Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme
-
Ratia, K., Saikatendu, K. S., Santarsiero, B. D., Barretto, N., Baker, S. C., Stevens, R. C., and Mesecar, A. D. (2006) Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme Proc. Natl. Acad. Sci. U. S. A. 103, 5717-5722 10.1073/pnas.0510851103
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 5717-5722
-
-
Ratia, K.1
Saikatendu, K.S.2
Santarsiero, B.D.3
Barretto, N.4
Baker, S.C.5
Stevens, R.C.6
Mesecar, A.D.7
-
68
-
-
0036001159
-
Structural basis of perturbed pKa values of catalytic groups in enzyme active sites
-
Harris, T. K. and Turner, G. J. (2002) Structural basis of perturbed pKa values of catalytic groups in enzyme active sites IUBMB Life 53, 85-98 10.1080/15216540211468
-
(2002)
IUBMB Life
, vol.53
, pp. 85-98
-
-
Harris, T.K.1
Turner, G.J.2
-
69
-
-
0021920109
-
Mechanism of action of cysteine proteinases: Oxyanion binding site is not essential in the hydrolysis of specific substrates
-
Asboth, B., Stokum, E., Khan, I. U., and Polgar, L. (1985) Mechanism of action of cysteine proteinases: oxyanion binding site is not essential in the hydrolysis of specific substrates Biochemistry 24, 606-609 10.1021/bi00324a010
-
(1985)
Biochemistry
, vol.24
, pp. 606-609
-
-
Asboth, B.1
Stokum, E.2
Khan, I.U.3
Polgar, L.4
-
70
-
-
0021094368
-
Transition-state stabilization at the oxyanion binding sites of serine and thiol proteinases: Hydrolyses of thiono and oxygen esters
-
Asboth, B. and Polgar, L. (1983) Transition-state stabilization at the oxyanion binding sites of serine and thiol proteinases: hydrolyses of thiono and oxygen esters Biochemistry 22, 117-122 10.1021/bi00270a017
-
(1983)
Biochemistry
, vol.22
, pp. 117-122
-
-
Asboth, B.1
Polgar, L.2
-
71
-
-
0023044226
-
The basic difference in catalyses by serine and cysteine proteinases resides in charge stabilization in the transition state
-
Polgar, L. and Asboth, B. (1986) The basic difference in catalyses by serine and cysteine proteinases resides in charge stabilization in the transition state J. Theor. Biol. 121, 323-326 10.1016/S0022-5193(86)80111-4
-
(1986)
J. Theor. Biol.
, vol.121
, pp. 323-326
-
-
Polgar, L.1
Asboth, B.2
-
72
-
-
84902359082
-
Structural and functional characterization of MERS coronavirus papain-like protease
-
Lin, M. H., Chuang, S. J., Chen, C. C., Cheng, S. C., Cheng, K. W., Lin, C. H., Sun, C. Y., and Chou, C. Y. (2014) Structural and functional characterization of MERS coronavirus papain-like protease J. Biomed. Sci. 21, 54 10.1186/1423-0127-21-54
-
(2014)
J. Biomed. Sci.
, vol.21
, pp. 54
-
-
Lin, M.H.1
Chuang, S.J.2
Chen, C.C.3
Cheng, S.C.4
Cheng, K.W.5
Lin, C.H.6
Sun, C.Y.7
Chou, C.Y.8
-
74
-
-
84894111449
-
Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease
-
Chou, C. Y., Lai, H. Y., Chen, H. Y., Cheng, S. C., Cheng, K. W., and Chou, Y. W. (2014) Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease Acta Crystallogr., Sect. D: Biol. Crystallogr. 70, 572-581 10.1107/S1399004713031040
-
(2014)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.70
, pp. 572-581
-
-
Chou, C.Y.1
Lai, H.Y.2
Chen, H.Y.3
Cheng, S.C.4
Cheng, K.W.5
Chou, Y.W.6
-
75
-
-
84973361423
-
-
Protein Data Bank entry 4PT5
-
Lei, H., Santarsiero, B. D., Lee, H., and Johnson, M. E. (2014) Crystal structure of PLpro from Middle East Respiratory Syndrome (MERS) coronavirus. Protein Data Bank entry 4PT5.
-
(2014)
Crystal Structure of PLpro from Middle East Respiratory Syndrome (MERS) Coronavirus
-
-
Lei, H.1
Santarsiero, B.D.2
Lee, H.3
Johnson, M.E.4
-
76
-
-
84976878698
-
Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors
-
Rawlings, N. D., Barrett, A. J., and Finn, R. D. (2016) Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors Nucleic Acids Res. 44, D343-D350 10.1093/nar/gkv1118
-
(2016)
Nucleic Acids Res.
, vol.44
, pp. D343-D350
-
-
Rawlings, N.D.1
Barrett, A.J.2
Finn, R.D.3
|