Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

PLoS Pathogens

Volumn 10, Issue 5, 2014, Pages

  Ratia, Kiira ^a   Kilianski, Andrew ^b   Baez Santos, Yahira M ^c   Baker, Susan C ^b   Mesecar, Andrew ^c  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3C-LIKE PROTEASE, SARS CORONAVIRUS; CYSTEINE PROTEINASE; CYTOKINE; ISG15 PROTEIN, HUMAN; UBIQUITIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CORONAVIRUS INFECTION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PROTEIN CONFORMATION; PROTEIN PROCESSING; SARS CORONAVIRUS; UBIQUITINATION; VIROLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CORONAVIRUS INFECTIONS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; CYTOKINES; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SARS VIRUS; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITINATION; UBIQUITINS; VIRAL PROTEINS;

EID: 84901670584     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004113     Document Type: Article

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