Structural and functional characterization of MERS coronavirus papain-like protease

Journal of Biomedical Science

Volumn 21, Issue 1, 2014, Pages

  Lin, Min Han ^a   Chuang, Shang Ju ^a   Chen, Chiao Che ^a   Cheng, Shu Chun ^a   Cheng, Kai Wen ^a   Lin, Chao Hsiung ^a   Sun, Chiao Yin ^b   Chou, Chi Yuan ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Antiviral target; Deubiquitination; MERS coronavirus; Papain like protease

Indexed keywords

METAL ION; MONOMER; PAPAIN; PROTEINASE; 3C LIKE PROTEASE, SARS CORONAVIRUS; 3C-LIKE PROTEASE, SARS CORONAVIRUS; ANTIVIRUS AGENT; CYSTEINE PROTEINASE; ION; METAL; VIRUS PROTEIN;

ARTICLE; CIRCULAR DICHROISM; CORONAVIRUS; EUROPE; FATALITY; FLUORESCENCE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; PURIFICATION; RNA VIRUS; SARS CORONAVIRUS; SAUDI ARABIA; STEADY STATE; ULTRACENTRIFUGATION; VIRUS MORPHOLOGY; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PROTEIN PROCESSING;

CORONAVIRUS; SARS CORONAVIRUS;

ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; EUROPE; GENE EXPRESSION REGULATION, VIRAL; HUMANS; IONS; METALS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; SARS VIRUS; VIRAL PROTEINS;

EID: 84902359082     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-21-54     Document Type: Article

References (29)

1. Emerging human coronaviruses-disease potential and preparedness. Anderson LJ, Baric RS, N Engl J Med 2012 367 19 1850 1852 10.1056/NEJMe1212300 23075144
2. Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? Chan JF, Li KS, To KK, Cheng VC, Chen H, Yuen KY, J Infect 2012 65 6 477 489 10.1016/j.jinf.2012.10.002 23072791
3. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA, N Engl J Med 2012 367 19 1814 1820 10.1056/NEJMoa1211721 23075143
4. In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection. Eckerle I, Muller MA, Kallies S, Gotthardt DN, Drosten C, Virol J 2013 10 359 10.1186/1743-422X-10-359 24364985
5. Hospital outbreak of Middle East respiratory syndrome coronavirus. Assiri A, McGeer A, Perl TM, Price CS, Al Rabeeah AA, Cummings DA, Alabdullatif ZN, Assad M, Almulhim A, Makhdoom H, Madani H, Alhakeem R, Al-Tawfiq JA, Cotten M, Watson SJ, Kellam P, Zumla AI, Memish ZA, Team KM-CI, N Engl J Med 2013 369 5 407 416 10.1056/NEJMoa1306742 23782161
6. Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Reusken CB, Haagmans BL, Muller MA, Gutierrez C, Godeke GJ, Meyer B, Muth D, Raj VS, Smits-De VL, Corman VM, Drexler JF, Smits SL, El Tahir YE, De Sousa R, van Beek J, Nowotny N, van Maanen K, Hidalgo-Hermoso E, Bosch BJ, Rottier P, Osterhaus A, Gortazar-Schmidt C, Drosten C, Koopmans MP, Lancet Infect Dis 2013 13 10 859 866 10.1016/S1473-3099(13)70164-6 23933067
7. Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors. Kilianski A, Mielech AM, Deng X, Baker SC, J Virol 2013 87 21 11955 11962 10.1128/JVI.02105-13 23986593
8. Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63. Chen Z, Wang Y, Ratia K, Mesecar AD, Wilkinson KD, Baker SC, J Virol 2007 81 11 6007 6018 10.1128/JVI.02747-06 17392370 (Pubitemid 46847037)
9. Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases. Clementz MA, Chen Z, Banach BS, Wang Y, Sun L, Ratia K, Baez-Santos YM, Wang J, Takayama J, Ghosh AK, Li K, Mesecar AD, Baker SC, J Virol 2010 84 9 4619 4629 10.1128/JVI.02406-09 20181693
10. Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease. Yang X, Chen X, Bian G, Tu J, Xing Y, Wang Y, Chen Z, J Gen Virol 2014 95 Pt 3 614 626 24362959
11. PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production. Zheng D, Chen G, Guo B, Cheng G, Tang H, Cell Res 2008 18 11 1105 1113 18957937
12. Structural basis for catalysis and ubiquitin recognition by the Severe acute respiratory syndrome coronavirus papain-like protease. Chou CY, Lai HY, Chen HY, Cheng SC, Cheng KW, Chou YW, Acta Crystallogr D Biol Crystallogr 2014 70 Pt 2 572 581 24531491
13. Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Hu M, Li P, Song L, Jeffrey PD, Chenova TA, Wilkinson KD, Cohen RE, Shi Y, EMBO J 2005 24 21 3747 3756 10.1038/sj.emboj.7600832 16211010 (Pubitemid 41581691)
14. Structural basis of ubiquitin recognition by the deubiquitinating protease USP2. Renatus M, Parrado SG, D'Arcy A, Eidhoff U, Gerhartz B, Hassiepen U, Pierrat B, Riedl R, Vinzenz D, Worpenberg S, Kroemer M, Structure 2006 14 8 1293 1302 10.1016/j.str.2006.06.012 16905103 (Pubitemid 44176373)
15. MERS-CoV papain-like protease has deISGylating and deubiquitinating activities. Mielech AM, Kilianski A, Baez-Santos YM, Mesecar AD, Baker SC, Virology 2014 450-451 64 70
16. Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Sreerama N, Woody RW, Anal Biochem 2000 287 2 252 260 10.1006/abio.2000.4880 11112271 (Pubitemid 32006234)
17. DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data. Whitmore L, Wallace BA, Nucleic Acids Res 2004 32 Web Server issue 668 673 15215473
18. Reversible unfolding of the severe acute respiratory syndrome coronavirus main protease in guanidinium chloride. Chang HP, Chou CY, Chang GG, Biophys J 2007 92 4 1374 1383 10.1529/biophysj.106.091736 17142288 (Pubitemid 46203198)
19. Differential domain structure stability of the severe acute respiratory syndrome coronavirus papain-like protease. Chou YW, Cheng SC, Lai HY, Chou CY, Arch Biochem Biophys 2012 520 2 74 80 10.1016/j.abb.2012.02.015 22391227
20. Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease. Cheng SC, Chang GG, Chou CY, Biophys J 2010 98 7 1327 1336 10.1016/j.bpj.2009.12.4272 20371333
21. Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments. Hsieh YH, Chou CY, J Biomed Sci 2011 18 4 10.1186/1423-0127-18-4 21219628
22. Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease. Wu CG, Cheng SC, Chen SC, Li JY, Fang YH, Chen YH, Chou CY, Acta Crystallogr D Biol Crystallogr 2013 69 Pt 5 747 755 23633583
23. Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling. Schuck P, Biophys J 2000 78 1606 1619 10.1016/S0006-3495(00)76713-0 10692345 (Pubitemid 30141584)
24. Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus. Chou CY, Chien CH, Han YS, Prebanda MT, Hsieh HP, Turk B, Chang GG, Chen X, Biochem Pharmacol 2008 75 8 1601 1609 10.1016/j.bcp.2008.01.005 18313035
25. Papain-like protease 1 from transmissible gastroenteritis virus: crystal structure and enzymatic activity toward viral and cellular substrates. Wojdyla JA, Manolaridis I, van Kasteren PB, Kikkert M, Snijder EJ, Gorbalenya AE, Tucker PA, J Virol 2010 84 19 10063 10073 10.1128/JVI.00898-10 20668092
26. Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation. Brown PH, Schuck P, Biophys J 2006 90 12 4651 4661 10.1529/biophysj.106.081372 16565040 (Pubitemid 43830909)
27. Toward the estimation of the absolute quality of individual protein structure models. Benkert P, Biasini M, Schwede T, Bioinformatics 2011 27 3 343 350 10.1093/bioinformatics/btq662 21134891
28. Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD, Proc Natl Acad Sci U S A 2006 103 15 5717 5722 10.1073/pnas.0510851103 16581910
29. Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition. Han YS, Chang GG, Juo CG, Lee HJ, Yeh SH, Hsu JT, Chen X, Biochemistry 2005 44 30 10349 10359 10.1021/bi0504761 16042412 (Pubitemid 41076830)