Inorganic arsenic induces apoptosis through downregulation of ube2d genes and p53 accumulation in rat proximal tubular cells

Journal of Toxicological Sciences

Volumn 38, Issue 6, 2013, Pages 815-820

  Tokumoto, Maki ^a,b,c   Lee, Jin Yong ^b   Fujiwara, Yasuyuki ^b   Uchiyama, Masanobu ^c,d   Satoh, Masahiko ^d  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

^c RIKEN   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; Inorganic arsenic; Inorganic mercury; p53; Ube2d family

Indexed keywords

ARSENIC; ARSENITE SODIUM; CADMIUM CHLORIDE; DNA FRAGMENT; MERCURIC CHLORIDE; MERCURY; PROTEIN P53; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CHEMILUMINESCENCE IMMUNOASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; GENE; GENE EXPRESSION; KIDNEY TUBULE CELL; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; UBE2D GENE; WESTERN BLOTTING;

RATTUS;

ANIMALS; APOPTOSIS; ARSENITES; CELL SURVIVAL; CELLS, CULTURED; DNA FRAGMENTATION; DOWN-REGULATION; GENE EXPRESSION; KIDNEY TUBULES, PROXIMAL; MERCURIC CHLORIDE; MULTIGENE FAMILY; RATS; SIGNAL TRANSDUCTION; SODIUM COMPOUNDS; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84887473604     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.38.815     Document Type: Article

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