Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells

Journal of Trace Elements in Medicine and Biology

Volumn 28, Issue 2, 2014, Pages 138-146

  Ebert, Franziska ^a   Leffers, Larissa ^a   Weber, Till ^a   Berndt, Svenia ^a   Mangerich, Aswin ^b   Beneke, Sascha ^c   Bürkle, Alexander ^b   Schwerdtle, Tanja ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Arsenite; Cellular bioavailability; Genotoxicity; Poly(ADP ribosyl)ation; Thio dimethylarsinic acid

Indexed keywords

ARSENIC; ARSENIC TRIOXIDE; CACODYLIC ACID; CASPASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; THIO DIMETHYLARSINIC ACID; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ARSINIC ACID DERIVATIVE; ADENOSINE DIPHOSPHATE RIBOSE; ARSENIC ACID DERIVATIVE; ARSENOSUGAR; CELL CYCLE PROTEIN; GADD45A PROTEIN, HUMAN; GLYCOSIDASE; HYDROGEN PEROXIDE; MONOSACCHARIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR PROTEIN; ORGANOARSENIC DERIVATIVE; POLY ADP-RIBOSE GLYCOHYDROLASE; RECOMBINANT PROTEIN; THIO-DIMETHYLARSINATE; THIOL DERIVATIVE;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; BAX GENE; BIOAVAILABILITY; CASPASE 2 GENE; CELL COUNT; CELL CYCLE; CELL DAMAGE; CELL DEATH; CELL STRESS; CELL VOLUME; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA DAMAGE; DNA REPAIR; G2 PHASE CELL CYCLE CHECKPOINT; GADD45A GENE; GAPDH GENE; GENE; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; M PHASE CELL CYCLE CHECKPOINT; PARG GENE; PARP 1 GENE; PRIORITY JOURNAL; S PHASE CELL CYCLE CHECKPOINT; CONCENTRATION (PARAMETERS); DIETARY INTAKE; IN VIVO STUDY; RISK FACTOR; SIGNAL TRANSDUCTION; UROTHELIUM; ANALOGS AND DERIVATIVES; APOPTOSIS; BLADDER; CELL LINE; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TOXICITY;

ALGAE;

ADENOSINE DIPHOSPHATE RIBOSE; APOPTOSIS; ARSENATES; ARSENIC; ARSENICALS; BIOLOGICAL AVAILABILITY; CACODYLIC ACID; CASPASE 2; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; GENE EXPRESSION REGULATION; GLYCOSIDE HYDROLASES; HUMANS; HYDROGEN PEROXIDE; MONOSACCHARIDES; NAD; NUCLEAR PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINANT PROTEINS; SULFHYDRYL COMPOUNDS; URINARY BLADDER;

EID: 84898032934     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2013.06.004     Document Type: Article

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