Crystal structure of the human sterol transporter ABCG5/ABCG8

Nature

Volumn 533, Issue 7604, 2016, Pages 561-564

  Lee, Jyh Yeuan ^a   Kinch, Lisa N ^a,b   Borek, Dominika M ^a,b   Wang, Jin ^a   Wang, Junmei ^c   Urbatsch, Ina L ^d   Xie, Xiao Song ^a   Grishin, Nikolai V ^a,b   Cohen, Jonathan C ^a   Otwinowski, Zbyszek ^a,b   Hobbs, Helen H ^a   Rosenbaum, Daniel M ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER G5; ABC TRANSPORTER G8; HYDROGEN; ABC TRANSPORTER; ABCG5 PROTEIN, HUMAN; ABCG8 PROTEIN, HUMAN; ADENOSINE TRIPHOSPHATASE; LIPID BILAYER; LIPOPROTEIN; NUCLEOTIDE; PHYTOSTEROL; STEROL;

BIOACCUMULATION; BIOCHEMISTRY; BIOMECHANICS; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIGESTIVE SYSTEM; LIPID; MUTATION; PROTEIN; STEROL;

ARTICLE; ASYMMETRIC CATALYSIS; COEVOLUTION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ELECTRON; HUMAN; HYDROGEN BOND; HYDROLYSIS; LIPID BILAYER; LIPID TRANSPORT; MISSENSE MUTATION; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE BINDING SITE; OUTER MEMBRANE; PRIORITY JOURNAL; X RAY DIFFRACTION; AMINO ACID SEQUENCE; BINDING SITE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; ENTEROPATHY; GENETICS; HYPERCHOLESTEROLEMIA; METABOLISM; MOLECULAR GENETICS; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

EUKARYOTA;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYPERCHOLESTEROLEMIA; INTESTINAL DISEASES; LIPID BILAYERS; LIPID METABOLISM, INBORN ERRORS; LIPOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PHYTOSTEROLS; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; STEROLS;

EID: 84969667882     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17666     Document Type: Article

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