메뉴 건너뛰기




Volumn 56, Issue 2, 2015, Pages 319-330

Relative roles of ABCG5/ABCG8 in liver and intestine

Author keywords

Bile; Cholesterol absorption; Sterols; Transport

Indexed keywords

ABC TRANSPORTER G5; ABC TRANSPORTER G8; CHOLESTEROL; CHOLESTEROL H 3; SITOSTEROL; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCG5 PROTEIN, MOUSE; ABCG8 PROTEIN, MOUSE; LIPOPROTEIN; PHYTOSTEROL;

EID: 84921833435     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M054544     Document Type: Article
Times cited : (132)

References (46)
  • 1
    • 0018841909 scopus 로고
    • Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: A case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis
    • Miettinen, T. A. 1980 . Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. Eur. J. Clin. Invest. 10 : 27-35 .
    • (1980) Eur. J. Clin. Invest. , vol.10 , pp. 27-35
    • Miettinen, T.A.1
  • 4
    • 9644281617 scopus 로고    scopus 로고
    • Disruption of cholesterol homeostasis by plant sterols
    • Yang, C., L. Yu, W. Li, F. Xu, J. C. Cohen, and H. H. Hobbs . 2004 . Disruption of cholesterol homeostasis by plant sterols. J. Clin. Invest. 114 : 813-822 .
    • (2004) J. Clin. Invest. , vol.114 , pp. 813-822
    • Yang, C.1    Yu, L.2    Li, W.3    Xu, F.4    Cohen, J.C.5    Hobbs, H.H.6
  • 5
    • 84872435630 scopus 로고    scopus 로고
    • Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolindefi cient mice
    • Solca, C., G. S. Tint, and S. B. Patel . 2013 . Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolindefi cient mice. J. Lipid Res. 54 : 397-409 .
    • (2013) J. Lipid Res. , vol.54 , pp. 397-409
    • Solca, C.1    Tint, G.S.2    Patel, S.B.3
  • 7
    • 0348111456 scopus 로고    scopus 로고
    • ABCG5 and ABCG8 are obligate heterodimers for protein traffi cking and biliary cholesterol excretion
    • Graf, G. A., L. Yu, W. P. Li, R. Gerard, P. L. Tuma, J. C. Cohen, and H. H. Hobbs . 2003 . ABCG5 and ABCG8 are obligate heterodimers for protein traffi cking and biliary cholesterol excretion. J. Biol. Chem. 278 : 48275-48282 .
    • (2003) J. Biol. Chem. , vol.278 , pp. 48275-48282
    • Graf, G.A.1    Yu, L.2    Li, W.P.3    Gerard, R.4    Tuma, P.L.5    Cohen, J.C.6    Hobbs, H.H.7
  • 9
    • 0024451905 scopus 로고
    • Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis
    • Salen, G., V. Shore, G. S. Tint, T. Forte, S. Shefer, I. Horak, E. Horak, B. Dayal, L. Nguyen, A. K. Batta, et al . 1989 . Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis. J. Lipid Res. 30 : 1319-1330 .
    • (1989) J. Lipid Res. , vol.30 , pp. 1319-1330
    • Salen, G.1    Shore, V.2    Tint, G.S.3    Forte, T.4    Shefer, S.5    Horak, I.6    Horak, E.7    Dayal, B.8    Nguyen, L.9    Batta, A.K.10
  • 10
    • 0029112257 scopus 로고
    • Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: Effect of sitostanol treatment
    • Lütjohann, D., I. Bjorkhem, U. F. Beil, and K. von Bergmann . 1995 . Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment. J. Lipid Res. 36 : 1763-1773 .
    • (1995) J. Lipid Res. , vol.36 , pp. 1763-1773
    • Lütjohann, D.1    Bjorkhem, I.2    Beil, U.F.3    Von Bergmann, K.4
  • 12
    • 0036733630 scopus 로고    scopus 로고
    • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    • Yu, L., J. Li-Hawkins, R. E. Hammer, K. E. Berge, J. D. Horton, J. C. Cohen, and H. H. Hobbs . 2002 . Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest. 110 : 671-680 .
    • (2002) J. Clin. Invest. , vol.110 , pp. 671-680
    • Yu, L.1    Li-Hawkins, J.2    Hammer, R.E.3    Berge, K.E.4    Horton, J.D.5    Cohen, J.C.6    Hobbs, H.H.7
  • 14
    • 3042601466 scopus 로고    scopus 로고
    • A mouse model of sitosterolemia: Absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
    • Klett, E. L., K. Lu, A. Kosters, E. Vink, M. H. Lee, M. Altenburg, S. Shefer, A. K. Batta, H. Yu, J. Chen, et al . 2004 . A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med. 2 : 5 .
    • (2004) BMC Med. , vol.2 , pp. 5
    • Klett, E.L.1    Lu, K.2    Kosters, A.3    Vink, E.4    Lee, M.H.5    Altenburg, M.6    Shefer, S.7    Batta, A.K.8    Yu, H.9    Chen, J.10
  • 15
    • 9144236921 scopus 로고    scopus 로고
    • Sitosterolemia in ABC-transporter G5-defi cient mice is aggravated on activation of the liver-X receptor
    • [Erratum. 2004. Gastroenterology . 126: 944.]
    • Plösch, T., V. W. Bloks, Y. Terasawa, S. Berdy, K. Siegler, F. Van Der Sluijs, I. P. Kema, A. K. Groen, B. Shan, F. Kuipers, et al . 2004 . Sitosterolemia in ABC-transporter G5-defi cient mice is aggravated on activation of the liver-X receptor. Gastroenterology . 126 : 290-300 . [Erratum. 2004. Gastroenterology . 126: 944.]
    • (2004) Gastroenterology , vol.126 , pp. 290-300
    • Plösch, T.1    Bloks, V.W.2    Terasawa, Y.3    Berdy, S.4    Siegler, K.5    Van Der Sluijs, F.6    Kema, I.P.7    Groen, A.K.8    Shan, B.9    Kuipers, F.10
  • 22
    • 11144257009 scopus 로고    scopus 로고
    • Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice
    • Kruit, J. K., T. Plosch, R. Havinga, R. Boverhof, P. H. Groot, A. K. Groen, and F. Kuipers . 2005 . Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice. Gastroenterology . 128 : 147-156 .
    • (2005) Gastroenterology , vol.128 , pp. 147-156
    • Kruit, J.K.1    Plosch, T.2    Havinga, R.3    Boverhof, R.4    Groot, P.H.5    Groen, A.K.6    Kuipers, F.7
  • 23
    • 84862804992 scopus 로고    scopus 로고
    • Biliary and nonbiliary contributions to reverse cholesterol transport
    • Temel, R. E., and J. M. Brown . 2012 . Biliary and nonbiliary contributions to reverse cholesterol transport. Curr. Opin. Lipidol. 23 : 85-90 .
    • (2012) Curr. Opin. Lipidol. , vol.23 , pp. 85-90
    • Temel, R.E.1    Brown, J.M.2
  • 25
    • 80051552124 scopus 로고    scopus 로고
    • Reverse cholesterol transport revisited: Contribution of biliary versus intestinal cholesterol excretion
    • Brufau, G., A. K. Groen, and F. Kuipers . 2011 . Reverse cholesterol transport revisited: contribution of biliary versus intestinal cholesterol excretion. Arterioscler. Thromb. Vasc. Biol. 31 : 1726-1733 .
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1726-1733
    • Brufau, G.1    Groen, A.K.2    Kuipers, F.3
  • 28
  • 29
    • 84862337034 scopus 로고    scopus 로고
    • Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes
    • Engelking, L. J., M. R. McFarlane, C. K. Li, and G. Liang . 2012 . Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes. J. Lipid Res. 53 : 1359-1368 .
    • (2012) J. Lipid Res. , vol.53 , pp. 1359-1368
    • Engelking, L.J.1    McFarlane, M.R.2    Li, C.K.3    Liang, G.4
  • 30
    • 0037088683 scopus 로고    scopus 로고
    • Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective defi ciency of sterol regulatory element-binding protein-1c
    • Liang, G., J. Yang, J. D. Horton, R. E. Hammer, J. L. Goldstein, and M. S. Brown . 2002 . Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective defi ciency of sterol regulatory element-binding protein-1c. J. Biol. Chem. 277 : 9520-9528 .
    • (2002) J. Biol. Chem. , vol.277 , pp. 9520-9528
    • Liang, G.1    Yang, J.2    Horton, J.D.3    Hammer, R.E.4    Goldstein, J.L.5    Brown, M.S.6
  • 32
    • 0027161715 scopus 로고
    • Evaluation of deuterated cholesterol and deuterated sitostanol for measurement of cholesterol absorption in humans
    • Lütjohann, D., C. O. Meese, J. R. Crouse III, and K. von Bergmann . 1993 . Evaluation of deuterated cholesterol and deuterated sitostanol for measurement of cholesterol absorption in humans. J. Lipid Res. 34 : 1039-1046 .
    • (1993) J. Lipid Res. , vol.34 , pp. 1039-1046
    • Lütjohann, D.1    Meese, C.O.2    Crouse, J.R.3    Von Bergmann, K.4
  • 34
    • 0036731990 scopus 로고    scopus 로고
    • Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface
    • Graf, G. A., W. P. Li, R. D. Gerard, I. Gelissen, A. White, J. C. Cohen, and H. H. Hobbs . 2002 . Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface. J. Clin. Invest. 110 : 659-669 .
    • (2002) J. Clin. Invest. , vol.110 , pp. 659-669
    • Graf, G.A.1    Li, W.P.2    Gerard, R.D.3    Gelissen, I.4    White, A.5    Cohen, J.C.6    Hobbs, H.H.7
  • 35
    • 0038782335 scopus 로고    scopus 로고
    • ABCG5 and ABCG8 are expressed in gallbladder epithelial cells
    • Tauscher, A., and R. Kuver . 2003 . ABCG5 and ABCG8 are expressed in gallbladder epithelial cells. Biochem. Biophys. Res. Commun. 307 : 1021-1028 .
    • (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 1021-1028
    • Tauscher, A.1    Kuver, R.2
  • 38
    • 0018101646 scopus 로고
    • Comparison of absorption and metabolism of beta-sitosterol and beta-sitostanol in rats
    • Ikeda, I., and M. Sugano . 1978 . Comparison of absorption and metabolism of beta-sitosterol and beta-sitostanol in rats. Atherosclerosis . 30 : 227-237 .
    • (1978) Atherosclerosis , vol.30 , pp. 227-237
    • Ikeda, I.1    Sugano, M.2
  • 39
    • 0022495268 scopus 로고
    • Effect of low-dose sitostanol on serum cholesterol in patients with hypercholesterolemia
    • Heinemann, T., O. Leiss, and K. von Bergmann . 1986 . Effect of low-dose sitostanol on serum cholesterol in patients with hypercholesterolemia. Atherosclerosis . 61 : 219-223 .
    • (1986) Atherosclerosis , vol.61 , pp. 219-223
    • Heinemann, T.1    Leiss, O.2    Von Bergmann, K.3
  • 40
    • 34247399882 scopus 로고    scopus 로고
    • Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8 (- / -) mice
    • Wang, H. H., S. B. Patel, M. C. Carey, and D. Q. Wang . 2007 . Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8 (- / -) mice. Hepatology . 45 : 998-1006 .
    • (2007) Hepatology , vol.45 , pp. 998-1006
    • Wang, H.H.1    Patel, S.B.2    Carey, M.C.3    Wang, D.Q.4
  • 41
    • 23244436716 scopus 로고    scopus 로고
    • Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8
    • Yu, L., K. von Bergmann, D. Lutjohann, H. H. Hobbs, and J. C. Cohen . 2005 . Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8. J. Lipid Res. 46 : 1739-1744 .
    • (2005) J. Lipid Res. , vol.46 , pp. 1739-1744
    • Yu, L.1    Von Bergmann, K.2    Lutjohann, D.3    Hobbs, H.H.4    Cohen, J.C.5
  • 42
    • 64749088618 scopus 로고    scopus 로고
    • Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8
    • Tang, W., Y. Ma, L. Jia, Y. A. Ioannou, J. P. Davies, and L. Yu . 2009 . Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8. J. Lipid Res. 50 : 293-300 .
    • (2009) J. Lipid Res. , vol.50 , pp. 293-300
    • Tang, W.1    Ma, Y.2    Jia, L.3    Ioannou, Y.A.4    Davies, J.P.5    Yu, L.6
  • 43
    • 0037040184 scopus 로고    scopus 로고
    • Control of cholesterol turnover in the mouse
    • Dietschy, J. M., and S. D. Turley . 2002 . Control of cholesterol turnover in the mouse. J. Biol. Chem. 277 : 3801-3804 .
    • (2002) J. Biol. Chem. , vol.277 , pp. 3801-3804
    • Dietschy, J.M.1    Turley, S.D.2
  • 44
    • 0025912236 scopus 로고
    • Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis
    • Bhattacharyya, A. K., W. E. Connor, D. S. Lin, M. M. McMurry, and R. S. Shulman . 1991 . Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis. Arterioscler. Thromb. 11 : 1287-1294 .
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 1287-1294
    • Bhattacharyya, A.K.1    Connor, W.E.2    Lin, D.S.3    McMurry, M.M.4    Shulman, R.S.5
  • 45
    • 0014262804 scopus 로고
    • Dietary sterols: Their relationship to atherosclerosis
    • Connor, W. E. 1968 . Dietary sterols: their relationship to atherosclerosis. J. Am. Diet. Assoc. 52 : 202-208 .
    • (1968) J. Am. Diet. Assoc. , vol.52 , pp. 202-208
    • Connor, W.E.1
  • 46
    • 79952297157 scopus 로고    scopus 로고
    • Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice
    • Nijstad, N., T. Gautier, F. Briand, D. J. Rader, and U. J. Tietge . 2011 . Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice. Gastroenterology . 140 : 1043-1051 .
    • (2011) Gastroenterology , vol.140 , pp. 1043-1051
    • Nijstad, N.1    Gautier, T.2    Briand, F.3    Rader, D.J.4    Tietge, U.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.