Chromothripsis and epigenomics complete causality criteria for cannabis- and addiction-connected carcinogenicity, congenital toxicity and heritable genotoxicity

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 789, Issue , 2016, Pages 15-25

  Reece, Albert Stuart ^a   Hulse, Gary Kenneth ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cannabis; Chromothripsis; Dose response relationship; Epigenetics; Foetal malformations; Heritable; Interdisciplinary; Microtubules; Oncogenesis; Population effects; Threshold dose; Transgenerational; Tubulin

Indexed keywords

CANNABIS; TETRAHYDROCANNABINOL; CANNABINOID;

ADDICTION; CANNABIS USE; CARCINOGENESIS; CARCINOGENICITY; CELL AGING; CELL CYCLE; CHROMOSOME REARRANGEMENT; CHROMOTHRIPSIS; CONGENITAL MALFORMATION; DISEASE ASSOCIATION; EPIGENETICS; GAMETOTOXICITY; GENETIC DISORDER; GENOTOXICITY; HUMAN; MICROTUBULE; MITOSIS SPINDLE; MUTAGENICITY; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; REVIEW; TERATOGENICITY; ZYGOTE TOXICITY; CANNABIS ADDICTION; CELL CYCLE CHECKPOINT; CHEMICALLY INDUCED; CONGENITAL ABNORMALITIES; DOSE RESPONSE; DRUG EFFECTS; GAMETOGENESIS; GENETIC EPIGENESIS; GENETICS; MICRONUCLEUS; NEOPLASMS;

CANNABINOIDS; CELL CYCLE CHECKPOINTS; CHROMOTHRIPSIS; CONGENITAL ABNORMALITIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIGENESIS, GENETIC; GAMETOGENESIS; HUMANS; MARIJUANA ABUSE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; NEOPLASMS;

EID: 84969592234     PISSN: 00275107     EISSN: 18792871     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2016.05.002     Document Type: Review

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