-
1
-
-
0034632717
-
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
-
Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 2000, 406:641-645.
-
(2000)
Nature
, vol.406
, pp. 641-645
-
-
Artandi, S.E.1
Chang, S.2
Lee, S.L.3
Alson, S.4
Gottlieb, G.J.5
Chin, L.6
DePinho, R.A.7
-
2
-
-
70749158525
-
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity
-
Baker D.J., Jin F., Jeganathan K.B., van Deursen J.M. Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell 2009, 16:475-486.
-
(2009)
Cancer Cell
, vol.16
, pp. 475-486
-
-
Baker, D.J.1
Jin, F.2
Jeganathan, K.B.3
van Deursen, J.M.4
-
3
-
-
70450176266
-
Deviant kinetochore microtubule dynamics underlie chromosomal instability
-
Bakhoum S.F., Genovese G., Compton D.A. Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr. Biol. 2009, 19:1937-1942.
-
(2009)
Curr. Biol.
, vol.19
, pp. 1937-1942
-
-
Bakhoum, S.F.1
Genovese, G.2
Compton, D.A.3
-
4
-
-
58149334818
-
Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
-
Bakhoum S.F., Thompson S.L., Manning A.L., Compton D.A. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nat. Cell Biol. 2009, 11:27-35.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 27-35
-
-
Bakhoum, S.F.1
Thompson, S.L.2
Manning, A.L.3
Compton, D.A.4
-
6
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J., Rezaei N., Liontos M., Karakaidos P., Kletsas D., Issaeva N., Vassiliou L.V., Kolettas E., Niforou K., Zoumpourlis V.C., et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 2006, 444:633-637.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
-
7
-
-
67649472398
-
Novel anticancer targets: revisiting ERBB2 and discovering ERBB3
-
Baselga J., Swain S.M. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat. Rev. Cancer 2009, 9:463-475.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 463-475
-
-
Baselga, J.1
Swain, S.M.2
-
8
-
-
3242881500
-
The cellular response to general and programmed DNA double strand breaks
-
Bassing C.H., Alt F.W. The cellular response to general and programmed DNA double strand breaks. DNA Repair (Amst.) 2004, 3:781-796.
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 781-796
-
-
Bassing, C.H.1
Alt, F.W.2
-
9
-
-
78650027929
-
Haplo-insufficiency: a driving force in cancer
-
Berger A.H., Pandolfi P.P. Haplo-insufficiency: a driving force in cancer. J. Pathol. 2011, 223:137-146.
-
(2011)
J. Pathol.
, vol.223
, pp. 137-146
-
-
Berger, A.H.1
Pandolfi, P.P.2
-
10
-
-
80051680291
-
A continuum model for tumour suppression
-
Berger A.H., Knudson A.G., Pandolfi P.P. A continuum model for tumour suppression. Nature 2011, 476:163-169.
-
(2011)
Nature
, vol.476
, pp. 163-169
-
-
Berger, A.H.1
Knudson, A.G.2
Pandolfi, P.P.3
-
11
-
-
79955525482
-
Nucleotide deficiency promotes genomic instability in early stages of cancer development
-
Bester A.C., Roniger M., Oren Y.S., Im M.M., Sarni D., Chaoat M., Bensimon A., Zamir G., Shewach D.S., Kerem B. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell 2011, 145:435-446.
-
(2011)
Cell
, vol.145
, pp. 435-446
-
-
Bester, A.C.1
Roniger, M.2
Oren, Y.S.3
Im, M.M.4
Sarni, D.5
Chaoat, M.6
Bensimon, A.7
Zamir, G.8
Shewach, D.S.9
Kerem, B.10
-
12
-
-
79960629889
-
Centrosomes and cilia in human disease
-
Bettencourt-Dias M., Hildebrandt F., Pellman D., Woods G., Godinho S.A. Centrosomes and cilia in human disease. Trends Genet. 2011, 27:307-315.
-
(2011)
Trends Genet.
, vol.27
, pp. 307-315
-
-
Bettencourt-Dias, M.1
Hildebrandt, F.2
Pellman, D.3
Woods, G.4
Godinho, S.A.5
-
13
-
-
67349227137
-
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
-
Chan K.L., Palmai-Pallag T., Ying S., Hickson I.D. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat. Cell Biol. 2009, 11:753-760.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 753-760
-
-
Chan, K.L.1
Palmai-Pallag, T.2
Ying, S.3
Hickson, I.D.4
-
14
-
-
0032109778
-
Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair
-
Chen C., Umezu K., Kolodner R.D. Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol. Cell 1998, 2:9-22.
-
(1998)
Mol. Cell
, vol.2
, pp. 9-22
-
-
Chen, C.1
Umezu, K.2
Kolodner, R.D.3
-
15
-
-
84155164320
-
Transient hypermutability, chromothripsis and replication-based mechanisms in the generation of concurrent clustered mutations
-
Chen J.M., Férec C., Cooper D.N. Transient hypermutability, chromothripsis and replication-based mechanisms in the generation of concurrent clustered mutations. Mutat. Res. 2012, 750:52-59.
-
(2012)
Mutat. Res.
, vol.750
, pp. 52-59
-
-
Chen, J.M.1
Férec, C.2
Cooper, D.N.3
-
16
-
-
0033553516
-
P53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L., Artandi S.E., Shen Q., Tam A., Lee S.L., Gottlieb G.J., Greider C.W., DePinho R.A. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 1999, 97:527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
17
-
-
78649336706
-
The DNA damage response: making it safe to play with knives
-
Ciccia A., Elledge S.J. The DNA damage response: making it safe to play with knives. Mol. Cell 2010, 40:179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
18
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta K., Ganem N.J., Dagher R., Lantermann A.B., Ivanova E.V., Pan Y., Nezi L., Protopopov A., Chowdhury D., Pellman D. DNA breaks and chromosome pulverization from errors in mitosis. Nature 2012, 482:53-58.
-
(2012)
Nature
, vol.482
, pp. 53-58
-
-
Crasta, K.1
Ganem, N.J.2
Dagher, R.3
Lantermann, A.B.4
Ivanova, E.V.5
Pan, Y.6
Nezi, L.7
Protopopov, A.8
Chowdhury, D.9
Pellman, D.10
-
19
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R., Fumagalli M., Cicalese A., Piccinin S., Gasparini P., Luise C., Schurra C., Garre' M., Nuciforo P.G., Bensimon A., et al. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 2006, 444:638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre', M.8
Nuciforo, P.G.9
Bensimon, A.10
-
20
-
-
0035081417
-
Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells
-
Elliott B., Jasin M. Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells. Mol. Cell. Biol. 2001, 21:2671-2682.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2671-2682
-
-
Elliott, B.1
Jasin, M.2
-
21
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
Fearon E.R. Molecular genetics of colorectal cancer. Annu. Rev. Pathol. 2011, 6:479-507.
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
22
-
-
84865232294
-
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
-
Gudjonsson T., Altmeyer M., Savic V., Toledo L., Dinant C., Grøfte M., Bartkova J., Poulsen M., Oka Y., Bekker-Jensen S., et al. TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell 2012, 150:697-709.
-
(2012)
Cell
, vol.150
, pp. 697-709
-
-
Gudjonsson, T.1
Altmeyer, M.2
Savic, V.3
Toledo, L.4
Dinant, C.5
Grøfte, M.6
Bartkova, J.7
Poulsen, M.8
Oka, Y.9
Bekker-Jensen, S.10
-
23
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
24
-
-
67651098662
-
Mechanisms of change in gene copy number
-
Hastings P.J., Lupski J.R., Rosenberg S.M., Ira G. Mechanisms of change in gene copy number. Nat. Rev. Genet. 2009, 10:551-564.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 551-564
-
-
Hastings, P.J.1
Lupski, J.R.2
Rosenberg, S.M.3
Ira, G.4
-
25
-
-
78149425175
-
Regulation of homologous recombination in eukaryotes
-
Heyer W.D., Ehmsen K.T., Liu J. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 2010, 44:113-139.
-
(2010)
Annu. Rev. Genet.
, vol.44
, pp. 113-139
-
-
Heyer, W.D.1
Ehmsen, K.T.2
Liu, J.3
-
26
-
-
84861853732
-
Losing balance: the origin and impact of aneuploidy in cancer
-
Holland A.J., Cleveland D.W. Losing balance: the origin and impact of aneuploidy in cancer. EMBO Rep. 2012, 13:501-514.
-
(2012)
EMBO Rep.
, vol.13
, pp. 501-514
-
-
Holland, A.J.1
Cleveland, D.W.2
-
27
-
-
79953314970
-
Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles
-
Howarth K.D., Pole J.C., Beavis J.C., Batty E.M., Newman S., Bignell G.R., Edwards P.A. Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles. Genome Res. 2011, 21:525-534.
-
(2011)
Genome Res.
, vol.21
, pp. 525-534
-
-
Howarth, K.D.1
Pole, J.C.2
Beavis, J.C.3
Batty, E.M.4
Newman, S.5
Bignell, G.R.6
Edwards, P.A.7
-
28
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
29
-
-
80053364894
-
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
-
Janssen A., van der Burg M., Szuhai K., Kops G.J., Medema R.H. Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 2011, 333:1895-1898.
-
(2011)
Science
, vol.333
, pp. 1895-1898
-
-
Janssen, A.1
van der Burg, M.2
Szuhai, K.3
Kops, G.J.4
Medema, R.H.5
-
30
-
-
80054698731
-
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
-
Kloosterman W.P., Hoogstraat M., Paling O., Tavakoli-Yaraki M., Renkens I., Vermaat J.S., van Roosmalen M.J., van Lieshout S., Nijman I.J., Roessingh W., et al. Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol. 2011, 12:R103.
-
(2011)
Genome Biol.
, vol.12
-
-
Kloosterman, W.P.1
Hoogstraat, M.2
Paling, O.3
Tavakoli-Yaraki, M.4
Renkens, I.5
Vermaat, J.S.6
van Roosmalen, M.J.7
van Lieshout, S.8
Nijman, I.J.9
Roessingh, W.10
-
31
-
-
84863105790
-
Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms
-
Kloosterman W.P., Tavakoli-Yaraki M., van Roosmalen M.J., van Binsbergen E., Renkens I., Duran K., Ballarati L., Vergult S., Giardino D., Hansson K., et al. Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms. Cell Rep. 2012, 1:648-655.
-
(2012)
Cell Rep.
, vol.1
, pp. 648-655
-
-
Kloosterman, W.P.1
Tavakoli-Yaraki, M.2
van Roosmalen, M.J.3
van Binsbergen, E.4
Renkens, I.5
Duran, K.6
Ballarati, L.7
Vergult, S.8
Giardino, D.9
Hansson, K.10
-
32
-
-
0037178722
-
Maintenance of genome stability in Saccharomyces cerevisiae
-
Kolodner R.D., Putnam C.D., Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002, 297:552-557.
-
(2002)
Science
, vol.297
, pp. 552-557
-
-
Kolodner, R.D.1
Putnam, C.D.2
Myung, K.3
-
33
-
-
35348988679
-
Paired-end mapping reveals extensive structural variation in the human genome
-
Korbel J.O., Urban A.E., Affourtit J.P., Godwin B., Grubert F., Simons J.F., Kim P.M., Palejev D., Carriero N.J., Du L., et al. Paired-end mapping reveals extensive structural variation in the human genome. Science 2007, 318:420-426.
-
(2007)
Science
, vol.318
, pp. 420-426
-
-
Korbel, J.O.1
Urban, A.E.2
Affourtit, J.P.3
Godwin, B.4
Grubert, F.5
Simons, J.F.6
Kim, P.M.7
Palejev, D.8
Carriero, N.J.9
Du, L.10
-
34
-
-
84975685847
-
From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
-
Lapuk A.V., Wu C., Wyatt A.W., McPherson A., McConeghy B.J., Brahmbhatt S., Mo F., Zoubeidi A., Anderson S., Bell R.H., et al. From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer. J. Pathol. 2012, 227:286-297.
-
(2012)
J. Pathol.
, vol.227
, pp. 286-297
-
-
Lapuk, A.V.1
Wu, C.2
Wyatt, A.W.3
McPherson, A.4
McConeghy, B.J.5
Brahmbhatt, S.6
Mo, F.7
Zoubeidi, A.8
Anderson, S.9
Bell, R.H.10
-
36
-
-
79551661935
-
Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site
-
Letessier A., Millot G.A., Koundrioukoff S., Lachagès A.M., Vogt N., Hansen R.S., Malfoy B., Brison O., Debatisse M. Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site. Nature 2011, 470:120-123.
-
(2011)
Nature
, vol.470
, pp. 120-123
-
-
Letessier, A.1
Millot, G.A.2
Koundrioukoff, S.3
Lachagès, A.M.4
Vogt, N.5
Hansen, R.S.6
Malfoy, B.7
Brison, O.8
Debatisse, M.9
-
37
-
-
0014587529
-
Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?
-
Li F.P., Fraumeni J.F. Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?. Ann. Intern. Med. 1969, 71:747-752.
-
(1969)
Ann. Intern. Med.
, vol.71
, pp. 747-752
-
-
Li, F.P.1
Fraumeni, J.F.2
-
38
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
39
-
-
80052916562
-
Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements
-
Liu P., Erez A., Nagamani S.C., Dhar S.U., Kołodziejska K.E., Dharmadhikari A.V., Cooper M.L., Wiszniewska J., Zhang F., Withers M.A., et al. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell 2011, 146:889-903.
-
(2011)
Cell
, vol.146
, pp. 889-903
-
-
Liu, P.1
Erez, A.2
Nagamani, S.C.3
Dhar, S.U.4
Kołodziejska, K.E.5
Dharmadhikari, A.V.6
Cooper, M.L.7
Wiszniewska, J.8
Zhang, F.9
Withers, M.A.10
-
40
-
-
84862491113
-
Mechanisms for recurrent and complex human genomic rearrangements
-
Liu P., Carvalho C.M., Hastings P.J., Lupski J.R. Mechanisms for recurrent and complex human genomic rearrangements. Curr. Opin. Genet. Dev. 2012, 22:211-220.
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 211-220
-
-
Liu, P.1
Carvalho, C.M.2
Hastings, P.J.3
Lupski, J.R.4
-
41
-
-
45549102966
-
Cancers exhibit a mutator phenotype: clinical implications
-
discussion 3557
-
Loeb L.A., Bielas J.H., Beckman R.A. Cancers exhibit a mutator phenotype: clinical implications. Cancer Res. 2008, 68:3551-3557. discussion 3557.
-
(2008)
Cancer Res.
, vol.68
, pp. 3551-3557
-
-
Loeb, L.A.1
Bielas, J.H.2
Beckman, R.A.3
-
42
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas C., Savic V., Bekker-Jensen S., Doil C., Neumann B., Pedersen R.S., Grøfte M., Chan K.L., Hickson I.D., Bartek J., Lukas J. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat. Cell Biol. 2011, 13:243-253.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grøfte, M.7
Chan, K.L.8
Hickson, I.D.9
Bartek, J.10
Lukas, J.11
-
43
-
-
34347349069
-
Genomic rearrangements and sporadic disease
-
Lupski J.R. Genomic rearrangements and sporadic disease. Nat. Genet. 2007, 39(7, Suppl):S43-S47.
-
(2007)
Nat. Genet.
, vol.39
, Issue.7 SUPPL
-
-
Lupski, J.R.1
-
44
-
-
79960693423
-
Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
-
Magrangeas F., Avet-Loiseau H., Munshi N.C., Minvielle S. Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood 2011, 118:675-678.
-
(2011)
Blood
, vol.118
, pp. 675-678
-
-
Magrangeas, F.1
Avet-Loiseau, H.2
Munshi, N.C.3
Minvielle, S.4
-
45
-
-
84863393824
-
Chromothripsis and human disease: piecing together the shattering process
-
Maher C.A., Wilson R.K. Chromothripsis and human disease: piecing together the shattering process. Cell 2012, 148:29-32.
-
(2012)
Cell
, vol.148
, pp. 29-32
-
-
Maher, C.A.1
Wilson, R.K.2
-
46
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
McClintock B. The stability of broken ends of chromosomes in Zea mays. Genetics 1941, 26:234-282.
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
McClintock, B.1
-
47
-
-
33847077659
-
Beyond the sequence: cellular organization of genome function
-
Misteli T. Beyond the sequence: cellular organization of genome function. Cell 2007, 128:787-800.
-
(2007)
Cell
, vol.128
, pp. 787-800
-
-
Misteli, T.1
-
48
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman F., Johansson B., Mertens F. The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer 2007, 7:233-245.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
49
-
-
84859216598
-
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
-
Molenaar J.J., Koster J., Zwijnenburg D.A., van Sluis P., Valentijn L.J., van der Ploeg I., Hamdi M., van Nes J., Westerman B.A., van Arkel J., et al. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature 2012, 483:589-593.
-
(2012)
Nature
, vol.483
, pp. 589-593
-
-
Molenaar, J.J.1
Koster, J.2
Zwijnenburg, D.A.3
van Sluis, P.4
Valentijn, L.J.5
van der Ploeg, I.6
Hamdi, M.7
van Nes, J.8
Westerman, B.A.9
van Arkel, J.10
-
50
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan M.E., Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 2010, 11:196-207.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
51
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
Musacchio A., Salmon E.D. The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 2007, 8:379-393.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
52
-
-
0035830498
-
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
-
Myung K., Datta A., Kolodner R.D. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 2001, 104:397-408.
-
(2001)
Cell
, vol.104
, pp. 397-408
-
-
Myung, K.1
Datta, A.2
Kolodner, R.D.3
-
53
-
-
84865227709
-
Cancer vulnerabilities unveiled by genomic loss
-
Nijhawan D., Zack T.I., Ren Y., Strickland M.R., Lamothe R., Schumacher S.E., Tsherniak A., Besche H.C., Rosenbluh J., Shehata S., et al. Cancer vulnerabilities unveiled by genomic loss. Cell 2012, 150:842-854.
-
(2012)
Cell
, vol.150
, pp. 842-854
-
-
Nijhawan, D.1
Zack, T.I.2
Ren, Y.3
Strickland, M.R.4
Lamothe, R.5
Schumacher, S.E.6
Tsherniak, A.7
Besche, H.C.8
Rosenbluh, J.9
Shehata, S.10
-
54
-
-
0000839280
-
Telomere dysfunction provokes regional amplification and deletion in cancer genomes
-
O'Hagan R.C., Chang S., Maser R.S., Mohan R., Artandi S.E., Chin L., DePinho R.A. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. Cancer Cell 2002, 2:149-155.
-
(2002)
Cancer Cell
, vol.2
, pp. 149-155
-
-
O'Hagan, R.C.1
Chang, S.2
Maser, R.S.3
Mohan, R.4
Artandi, S.E.5
Chin, L.6
DePinho, R.A.7
-
55
-
-
77649180958
-
Telomeres: protecting chromosomes against genome instability
-
O'Sullivan R.J., Karlseder J. Telomeres: protecting chromosomes against genome instability. Nat. Rev. Mol. Cell Biol. 2010, 11:171-181.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 171-181
-
-
O'Sullivan, R.J.1
Karlseder, J.2
-
56
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W., de Lange T. How shelterin protects mammalian telomeres. Annu. Rev. Genet. 2008, 42:301-334.
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
57
-
-
0014938777
-
Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis
-
Rao P.N., Johnson R.T. Mammalian cell fusion: studies on the regulation of DNA synthesis and mitosis. Nature 1970, 225:159-164.
-
(1970)
Nature
, vol.225
, pp. 159-164
-
-
Rao, P.N.1
Johnson, R.T.2
-
58
-
-
84862907577
-
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
-
Rausch T., Jones D.T., Zapatka M., Stütz A.M., Zichner T., Weischenfeldt J., Jäger N., Remke M., Shih D., Northcott P.A., et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 2012, 148:59-71.
-
(2012)
Cell
, vol.148
, pp. 59-71
-
-
Rausch, T.1
Jones, D.T.2
Zapatka, M.3
Stütz, A.M.4
Zichner, T.5
Weischenfeldt, J.6
Jäger, N.7
Remke, M.8
Shih, D.9
Northcott, P.A.10
-
59
-
-
75149134769
-
Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis
-
Reid B.J., Li X., Galipeau P.C., Vaughan T.L. Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat. Rev. Cancer 2010, 10:87-101.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 87-101
-
-
Reid, B.J.1
Li, X.2
Galipeau, P.C.3
Vaughan, T.L.4
-
60
-
-
0347951257
-
Karyotypic complexity of the NCI-60 drug-screening panel
-
Roschke A.V., Tonon G., Gehlhaus K.S., McTyre N., Bussey K.J., Lababidi S., Scudiero D.A., Weinstein J.N., Kirsch I.R. Karyotypic complexity of the NCI-60 drug-screening panel. Cancer Res. 2003, 63:8634-8647.
-
(2003)
Cancer Res.
, vol.63
, pp. 8634-8647
-
-
Roschke, A.V.1
Tonon, G.2
Gehlhaus, K.S.3
McTyre, N.4
Bussey, K.J.5
Lababidi, S.6
Scudiero, D.A.7
Weinstein, J.N.8
Kirsch, I.R.9
-
61
-
-
84555196106
-
BRCA1 and BRCA2: different roles in a common pathway of genome protection
-
Roy R., Chun J., Powell S.N. BRCA1 and BRCA2: different roles in a common pathway of genome protection. Nat. Rev. Cancer 2012, 12:68-78.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 68-78
-
-
Roy, R.1
Chun, J.2
Powell, S.N.3
-
62
-
-
27744455447
-
Trashing the genome: the role of nucleases during apoptosis
-
Samejima K., Earnshaw W.C. Trashing the genome: the role of nucleases during apoptosis. Nat. Rev. Mol. Cell Biol. 2005, 6:677-688.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 677-688
-
-
Samejima, K.1
Earnshaw, W.C.2
-
63
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
San Filippo J., Sung P., Klein H. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 2008, 77:229-257.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
64
-
-
77649191573
-
Genome destabilization by homologous recombination in the germ line
-
Sasaki M., Lange J., Keeney S. Genome destabilization by homologous recombination in the germ line. Nat. Rev. Mol. Cell Biol. 2010, 11:182-195.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 182-195
-
-
Sasaki, M.1
Lange, J.2
Keeney, S.3
-
65
-
-
75149140916
-
Mitotic chromosomal instability and cancer: mouse modelling of the human disease
-
Schvartzman J.M., Sotillo R., Benezra R. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat. Rev. Cancer 2010, 10:102-115.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 102-115
-
-
Schvartzman, J.M.1
Sotillo, R.2
Benezra, R.3
-
66
-
-
84868103798
-
New insights into the troubles of aneuploidy
-
Siegel J.J., Amon A. New insights into the troubles of aneuploidy. Annu. Rev. Cell Dev. Biol. 2012, 28:189-214.
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 189-214
-
-
Siegel, J.J.1
Amon, A.2
-
67
-
-
84863541457
-
Recurrent hemizygous deletions in cancers may optimize proliferative potential
-
Solimini N.L., Xu Q., Mermel C.H., Liang A.C., Schlabach M.R., Luo J., Burrows A.E., Anselmo A.N., Bredemeyer A.L., Li M.Z., et al. Recurrent hemizygous deletions in cancers may optimize proliferative potential. Science 2012, 337:104-109.
-
(2012)
Science
, vol.337
, pp. 104-109
-
-
Solimini, N.L.1
Xu, Q.2
Mermel, C.H.3
Liang, A.C.4
Schlabach, M.R.5
Luo, J.6
Burrows, A.E.7
Anselmo, A.N.8
Bredemeyer, A.L.9
Li, M.Z.10
-
68
-
-
80051874823
-
Mutational inactivation of STAG2 causes aneuploidy in human cancer
-
Solomon D.A., Kim T., Diaz-Martinez L.A., Fair J., Elkahloun A.G., Harris B.T., Toretsky J.A., Rosenberg S.A., Shukla N., Ladanyi M., et al. Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 2011, 333:1039-1043.
-
(2011)
Science
, vol.333
, pp. 1039-1043
-
-
Solomon, D.A.1
Kim, T.2
Diaz-Martinez, L.A.3
Fair, J.4
Elkahloun, A.G.5
Harris, B.T.6
Toretsky, J.A.7
Rosenberg, S.A.8
Shukla, N.9
Ladanyi, M.10
-
69
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens P.J., McBride D.J., Lin M.L., Varela I., Pleasance E.D., Simpson J.T., Stebbings L.A., Leroy C., Edkins S., Mudie L.J., et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009, 462:1005-1010.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
McBride, D.J.2
Lin, M.L.3
Varela, I.4
Pleasance, E.D.5
Simpson, J.T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Mudie, L.J.10
-
70
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens P.J., Greenman C.D., Fu B., Yang F., Bignell G.R., Mudie L.J., Pleasance E.D., Lau K.W., Beare D., Stebbings L.A., et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011, 144:27-40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
Yang, F.4
Bignell, G.R.5
Mudie, L.J.6
Pleasance, E.D.7
Lau, K.W.8
Beare, D.9
Stebbings, L.A.10
-
73
-
-
79952120598
-
Cancer: when catastrophe strikes a cell
-
Tubio J.M., Estivill X. Cancer: when catastrophe strikes a cell. Nature 2011, 470:476-477.
-
(2011)
Nature
, vol.470
, pp. 476-477
-
-
Tubio, J.M.1
Estivill, X.2
-
74
-
-
77957219796
-
Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis
-
Uetake Y., Sluder G. Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis. Curr. Biol. 2010, 20:1666-1671.
-
(2010)
Curr. Biol.
, vol.20
, pp. 1666-1671
-
-
Uetake, Y.1
Sluder, G.2
-
75
-
-
10744233937
-
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
-
Umar A., Boland C.R., Terdiman J.P., Syngal S., de la Chapelle A., Rüschoff J., Fishel R., Lindor N.M., Burgart L.J., Hamelin R., et al. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J. Natl. Cancer Inst. 2004, 96:261-268.
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 261-268
-
-
Umar, A.1
Boland, C.R.2
Terdiman, J.P.3
Syngal, S.4
de la Chapelle, A.5
Rüschoff, J.6
Fishel, R.7
Lindor, N.M.8
Burgart, L.J.9
Hamelin, R.10
-
76
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B., Kinzler K.W. Cancer genes and the pathways they control. Nat. Med. 2004, 10:789-799.
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
77
-
-
33747888634
-
Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells
-
Weinstock D.M., Richardson C.A., Elliott B., Jasin M. Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells. DNA Repair (Amst.) 2006, 5:1065-1074.
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 1065-1074
-
-
Weinstock, D.M.1
Richardson, C.A.2
Elliott, B.3
Jasin, M.4
-
78
-
-
33845905779
-
The natural history of cervical HPV infection: unresolved issues
-
Woodman C.B., Collins S.I., Young L.S. The natural history of cervical HPV infection: unresolved issues. Nat. Rev. Cancer 2007, 7:11-22.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 11-22
-
-
Woodman, C.B.1
Collins, S.I.2
Young, L.S.3
-
79
-
-
84861428789
-
A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions
-
Xue W., Kitzing T., Roessler S., Zuber J., Krasnitz A., Schultz N., Revill K., Weissmueller S., Rappaport A.R., Simon J., et al. A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc. Natl. Acad. Sci. USA 2012, 109:8212-8217.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 8212-8217
-
-
Xue, W.1
Kitzing, T.2
Roessler, S.3
Zuber, J.4
Krasnitz, A.5
Schultz, N.6
Revill, K.7
Weissmueller, S.8
Rappaport, A.R.9
Simon, J.10
-
80
-
-
84871027741
-
Human subtelomeric copy number gains suggest a DNA replication mechanism for formation: beyond breakage-fusion-bridge for telomere stabilization
-
Published online August 14, 2012
-
Yatsenko S.A., Hixson P., Roney E.K., Scott D.A., Schaaf C.P., Ng Y.T., Palmer R., Fisher R.B., Patel A., Cheung S.W., Lupski J.R. Human subtelomeric copy number gains suggest a DNA replication mechanism for formation: beyond breakage-fusion-bridge for telomere stabilization. Hum. Genet. 2012, Published online August 14, 2012. 10.1007/s00439-012-1216-9.
-
(2012)
Hum. Genet.
-
-
Yatsenko, S.A.1
Hixson, P.2
Roney, E.K.3
Scott, D.A.4
Schaaf, C.P.5
Ng, Y.T.6
Palmer, R.7
Fisher, R.B.8
Patel, A.9
Cheung, S.W.10
Lupski, J.R.11
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