메뉴 건너뛰기




Volumn 3, Issue NOV, 2015, Pages

The potential of silk and silk-like proteins as natural mucoadhesive biopolymers for controlled drug delivery

Author keywords

Aggregate silk; Biopolymers; Drug delivery; Mucoadhesive; Sericin; Silk

Indexed keywords


EID: 84969508876     PISSN: None     EISSN: 22962646     Source Type: Journal    
DOI: 10.3389/fchem.2015.00065     Document Type: Short Survey
Times cited : (31)

References (89)
  • 2
    • 0035313349 scopus 로고    scopus 로고
    • Novel mucoadhesive polymer prepared by template polymerization of acrylic acid in the presence of silk sericin
    • Ahn, J., Choi, H., Lee, K., Nahm, J., and Cho, C. (2001). Novel mucoadhesive polymer prepared by template polymerization of acrylic acid in the presence of silk sericin. J. Appl. Polym. Sci. 80, 274-280. doi: 10.1002/1097-4628(20010411)80:2<274::AID-APP1096>3.0.CO;2-G
    • (2001) J. Appl. Polym. Sci , vol.80 , pp. 274-280
    • Ahn, J.1    Choi, H.2    Lee, K.3    Nahm, J.4    Cho, C.5
  • 3
    • 84924897998 scopus 로고    scopus 로고
    • Ubiquitous distribution of salts and proteins in spider glue enhances spider silk adhesion
    • Amarpuri, G., Chaurasia, V., Jain, D., Blackledge, T. A., and Dhinojwala, A. (2015). Ubiquitous distribution of salts and proteins in spider glue enhances spider silk adhesion. Sci. Rep. 5:9030. doi: 10.1038/srep09030
    • (2015) Sci. Rep , vol.5 , pp. 9030
    • Amarpuri, G.1    Chaurasia, V.2    Jain, D.3    Blackledge, T.A.4    Dhinojwala, A.5
  • 4
    • 84881607396 scopus 로고    scopus 로고
    • Morphology and composition of the spider major ampullate gland and dragline silk
    • Andersson, M., Holm, L., Ridderstråle, Y., Johansson, J., and Rising, A. (2013). Morphology and composition of the spider major ampullate gland and dragline silk. Biomacromolecules 14, 2945-2952. doi: 10.1021/bm400898t
    • (2013) Biomacromolecules , vol.14 , pp. 2945-2952
    • Andersson, M.1    Holm, L.2    Ridderstråle, Y.3    Johansson, J.4    Rising, A.5
  • 5
    • 60749111451 scopus 로고    scopus 로고
    • Mucoadhesive polymeric platforms for controlled drug delivery
    • Andrews, G. P., Laverty, T. P., and Jones, D. S. (2009). Mucoadhesive polymeric platforms for controlled drug delivery. Eur. J. Pharm. Biopharm. 71, 505-518. doi: 10.1016/j.ejpb.2008.09.028
    • (2009) Eur. J. Pharm. Biopharm , vol.71 , pp. 505-518
    • Andrews, G.P.1    Laverty, T.P.2    Jones, D.S.3
  • 6
    • 84885666813 scopus 로고    scopus 로고
    • Self-tensioning aquatic caddisfly silk: Ca2+-dependent structure, strength, and load cycle hysteresis
    • Ashton, N. N., Roe, D. R., Weiss, R. B., Cheatham, T. E., and Stewart, R. J. (2013). Self-tensioning aquatic caddisfly silk: Ca2+-dependent structure, strength, and load cycle hysteresis. Biomacromolecules 14, 3668-3681. doi: 10.1021/bm401036z
    • (2013) Biomacromolecules , vol.14 , pp. 3668-3681
    • Ashton, N.N.1    Roe, D.R.2    Weiss, R.B.3    Cheatham, T.E.4    Stewart, R.J.5
  • 7
    • 0037073656 scopus 로고    scopus 로고
    • Clinical evaluation of bioadhesive ophthalmic drug inserts (BODI) for the treatment of external ocular infections in dogs
    • Baeyens, V., Felt-Baeyens, O., Rougier, S., Pheulpin, S., Boisramé, B., and Gurny, R. (2002). Clinical evaluation of bioadhesive ophthalmic drug inserts (BODI) for the treatment of external ocular infections in dogs. J. Control. Release Off. J. Control. Release Soc. 85, 163-168. doi: 10.1016/S0168-3659(02)00284-5
    • (2002) J. Control. Release Off. J. Control. Release Soc , vol.85 , pp. 163-168
    • Baeyens, V.1    Felt-Baeyens, O.2    Rougier, S.3    Pheulpin, S.4    Boisramé, B.5    Gurny, R.6
  • 9
    • 16844379775 scopus 로고    scopus 로고
    • Bioadhesive dosage forms for esophageal drug delivery
    • Batchelor, H. (2005). Bioadhesive dosage forms for esophageal drug delivery. Pharm. Res. 22, 175-181. doi: 10.1007/s11095-004-1183-5
    • (2005) Pharm. Res , vol.22 , pp. 175-181
    • Batchelor, H.1
  • 10
    • 0032956002 scopus 로고    scopus 로고
    • Comparative in vitro study of different chitosan-complexing agent conjugates
    • Bernkop-Schnürch, A., and Freudl, J. (1999). Comparative in vitro study of different chitosan-complexing agent conjugates. Pharmazie 54, 369-371.
    • (1999) Pharmazie , vol.54 , pp. 369-371
    • Bernkop-Schnürch, A.1    Freudl, J.2
  • 13
    • 70350418753 scopus 로고    scopus 로고
    • Pyriform spidroin 1, a novel member of the silk gene family that anchors dragline silk fibers in attachment discs of the black widow spider, Latrodectus hesperus
    • Blasingame, E., Tuton-Blasingame, T., Larkin, L., Falick, A. M., Zhao, L., Fong, J., et al. (2009). Pyriform spidroin 1, a novel member of the silk gene family that anchors dragline silk fibers in attachment discs of the black widow spider, Latrodectus hesperus. J. Biol. Chem. 284, 29097-29108. doi: 10.1074/jbc.M109.021378
    • (2009) J. Biol. Chem , vol.284 , pp. 29097-29108
    • Blasingame, E.1    Tuton-Blasingame, T.2    Larkin, L.3    Falick, A.M.4    Zhao, L.5    Fong, J.6
  • 14
    • 84877753912 scopus 로고    scopus 로고
    • Taking tissue adhesives to the future: from traditional synthetic to new biomimetic approaches
    • Bré, L. P., Zheng, Y., Pêgo, A. P., and Wang, W. (2013). Taking tissue adhesives to the future: from traditional synthetic to new biomimetic approaches. Biomater Sci 1, 239-253. doi: 10.1039/C2BM00121G
    • (2013) Biomater Sci , vol.1 , pp. 239-253
    • Bré, L.P.1    Zheng, Y.2    Pêgo, A.P.3    Wang, W.4
  • 15
    • 33846799473 scopus 로고    scopus 로고
    • Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles
    • Bravo-Osuna, I., Vauthier, C., Farabollini, A., Palmieri, G. F., and Ponchel, G. (2007). Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles. Biomaterials 28, 2233-2243. doi: 10.1016/j.biomaterials.2007.01.005
    • (2007) Biomaterials , vol.28 , pp. 2233-2243
    • Bravo-Osuna, I.1    Vauthier, C.2    Farabollini, A.3    Palmieri, G.F.4    Ponchel, G.5
  • 16
    • 58549108231 scopus 로고    scopus 로고
    • Simulation of flow in the silk gland
    • Breslauer, D. N., Lee, L. P., and Muller, S. J. (2009). Simulation of flow in the silk gland. Biomacromolecules 10, 49-57. doi: 10.1021/bm800752x
    • (2009) Biomacromolecules , vol.10 , pp. 49-57
    • Breslauer, D.N.1    Lee, L.P.2    Muller, S.J.3
  • 18
    • 77949909759 scopus 로고    scopus 로고
    • Enhancement of poly(ethylene glycol) mucoadsorption by biomimetic end group functionalization
    • Catron, N. D., Lee, H., and Messersmith, P. B. (2006). Enhancement of poly(ethylene glycol) mucoadsorption by biomimetic end group functionalization. Biointerphases 1, 134. doi: 10.1116/1.2422894
    • (2006) Biointerphases , vol.1 , pp. 134
    • Catron, N.D.1    Lee, H.2    Messersmith, P.B.3
  • 19
    • 0036279805 scopus 로고    scopus 로고
    • The use of xanthan gum in an ophthalmic liquid dosage form: rheological characterization of the interaction with mucin
    • Ceulemans, J., Vinckier, I., and Ludwig, A. (2002). The use of xanthan gum in an ophthalmic liquid dosage form: rheological characterization of the interaction with mucin. J. Pharm. Sci. 91, 1117-1127. doi: 10.1002/jps.10106
    • (2002) J. Pharm. Sci , vol.91 , pp. 1117-1127
    • Ceulemans, J.1    Vinckier, I.2    Ludwig, A.3
  • 20
    • 57149144115 scopus 로고    scopus 로고
    • Effect of thiolated polymers to textural and mucoadhesive properties of vaginal gel formulations prepared with polycarbophil and chitosan
    • Cevher, E., Sensoy, D., Taha, M. A. M., and Araman, A. (2008a). Effect of thiolated polymers to textural and mucoadhesive properties of vaginal gel formulations prepared with polycarbophil and chitosan. AAPS Pharm. Sci. Tech. 9, 953-965. doi: 10.1208/s12249-008-9132-y
    • (2008) AAPS Pharm. Sci. Tech , vol.9 , pp. 953-965
    • Cevher, E.1    Sensoy, D.2    Taha, M.A.M.3    Araman, A.4
  • 21
    • 38149103499 scopus 로고    scopus 로고
    • Evaluation of mechanical and mucoadhesive properties of clomiphene citrate gel formulations containing carbomers and their thiolated derivatives
    • Cevher, E., Taha, M. A. M., Orlu, M., and Araman, A. (2008b). Evaluation of mechanical and mucoadhesive properties of clomiphene citrate gel formulations containing carbomers and their thiolated derivatives. Drug Deliv. 15, 57-67. doi: 10.1080/10717540701829234
    • (2008) Drug Deliv , vol.15 , pp. 57-67
    • Cevher, E.1    Taha, M.A.M.2    Orlu, M.3    Araman, A.4
  • 22
    • 70350063816 scopus 로고    scopus 로고
    • Spider web glue: two proteins expressed from opposite strands of the same DNA sequence
    • Choresh, O., Bayarmagnai, B., and Lewis, R. V. (2009). Spider web glue: two proteins expressed from opposite strands of the same DNA sequence. Biomacromolecules 10, 2852-2856. doi: 10.1021/bm900681w
    • (2009) Biomacromolecules , vol.10 , pp. 2852-2856
    • Choresh, O.1    Bayarmagnai, B.2    Lewis, R.V.3
  • 23
    • 0034734982 scopus 로고    scopus 로고
    • Lectin-mediated mucosal delivery of drugs and microparticles
    • Clark, M. A., Hirst, B. H., and Jepson, M. A. (2000). Lectin-mediated mucosal delivery of drugs and microparticles. Adv. Drug Deliv. Rev. 43, 207-223. doi: 10.1016/S0169-409X(00)00070-3
    • (2000) Adv. Drug Deliv. Rev , vol.43 , pp. 207-223
    • Clark, M.A.1    Hirst, B.H.2    Jepson, M.A.3
  • 24
    • 79960799453 scopus 로고    scopus 로고
    • Mucoadhesive nanomedicines: characterization and modulation of mucoadhesion at the nanoscale
    • Das Neves, J., Bahia, M. F., Amiji, M. M., and Sarmento, B. (2011). Mucoadhesive nanomedicines: characterization and modulation of mucoadhesion at the nanoscale. Expert Opin. Drug Deliv. 8, 1085-1104. doi: 10.1517/17425247.2011.586334
    • (2011) Expert Opin. Drug Deliv , vol.8 , pp. 1085-1104
    • Das Neves, J.1    Bahia, M.F.2    Amiji, M.M.3    Sarmento, B.4
  • 25
    • 76149139778 scopus 로고    scopus 로고
    • Mucoadhesion: a review of characterization techniques
    • Davidovich-Pinhas, M., and Bianco-Peled, H. (2010). Mucoadhesion: a review of characterization techniques. Expert Opin. Drug Deliv. 7, 259-271. doi: 10.1517/17425240903473134
    • (2010) Expert Opin. Drug Deliv , vol.7 , pp. 259-271
    • Davidovich-Pinhas, M.1    Bianco-Peled, H.2
  • 26
    • 0037437096 scopus 로고    scopus 로고
    • Polymer relationships during preparation of chitosan-alginate and poly-l-lysine-alginate nanospheres
    • De, S. (2003). Polymer relationships during preparation of chitosan-alginate and poly-l-lysine-alginate nanospheres. J. Controlled Release 89, 101-112. doi: 10.1016/S0168-3659(03)00098-1
    • (2003) J. Controlled Release , vol.89 , pp. 101-112
    • De, S.1
  • 27
    • 84923257728 scopus 로고    scopus 로고
    • Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery
    • Dong, Y., Dong, P., Huang, D., Mei, L., Xia, Y., Wang, Z., et al. (2015). Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery. Eur. J. Pharm. Biopharm. 91, 82-90. doi: 10.1016/j.ejpb.2015.01.018
    • (2015) Eur. J. Pharm. Biopharm , vol.91 , pp. 82-90
    • Dong, Y.1    Dong, P.2    Huang, D.3    Mei, L.4    Xia, Y.5    Wang, Z.6
  • 28
    • 84946833216 scopus 로고    scopus 로고
    • 'Bioadhesive systems for drug delivery, '
    • eds H. Bianco-Peled and M. Davidovich-Pinhas (Boca Raton, FL: CRC Press)
    • Donnelly, R. F., and Woolfson, A. D. (2015). "Bioadhesive systems for drug delivery, "in Bioadhesion and Biomimetics: From Nature to Applications, eds H. Bianco-Peled and M. Davidovich-Pinhas (Boca Raton, FL: CRC Press), 235-260.
    • (2015) Bioadhesion and Biomimetics: From Nature to Applications , pp. 235-260
    • Donnelly, R.F.1    Woolfson, A.D.2
  • 29
    • 84255173353 scopus 로고    scopus 로고
    • Mucoadhesive gels designed for the controlled release of chlorhexidine in the oral cavity
    • Fini, A., Bergamante, V., and Ceschel, G. C. (2011). Mucoadhesive gels designed for the controlled release of chlorhexidine in the oral cavity. Pharmaceutics 3, 665-679. doi: 10.3390/pharmaceutics3040665
    • (2011) Pharmaceutics , vol.3 , pp. 665-679
    • Fini, A.1    Bergamante, V.2    Ceschel, G.C.3
  • 30
    • 33746474818 scopus 로고    scopus 로고
    • Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan-a review
    • George, M., and Abraham, T. E. (2006). Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan-a review. J. Control. Release Off. J. Control. Release Soc. 114, 1-14. doi: 10.1016/j.jconrel.2006.04.017
    • (2006) J. Control. Release Off. J. Control. Release Soc , vol.114 , pp. 1-14
    • George, M.1    Abraham, T.E.2
  • 31
    • 78650292103 scopus 로고    scopus 로고
    • Synthetic spider silk fibers spun from Pyriform Spidroin 2, a glue silk protein discovered in orb-weaving spider attachment discs
    • Geurts, P., Zhao, L., Hsia, Y., Gnesa, E., Tang, S., Jeffery, F., et al. (2010). Synthetic spider silk fibers spun from Pyriform Spidroin 2, a glue silk protein discovered in orb-weaving spider attachment discs. Biomacromolecules 11, 3495-3503. doi: 10.1021/bm101002w
    • (2010) Biomacromolecules , vol.11 , pp. 3495-3503
    • Geurts, P.1    Zhao, L.2    Hsia, Y.3    Gnesa, E.4    Tang, S.5    Jeffery, F.6
  • 33
    • 26644434123 scopus 로고    scopus 로고
    • Comparison of the mucoadhesive properties of various polymers
    • Grabovac, V., Guggi, D., and Bernkopschnurch, A. (2005). Comparison of the mucoadhesive properties of various polymers. Adv. Drug Deliv. Rev. 57, 1713-1723. doi: 10.1016/j.addr.2005.07.006
    • (2005) Adv. Drug Deliv. Rev , vol.57 , pp. 1713-1723
    • Grabovac, V.1    Guggi, D.2    Bernkopschnurch, A.3
  • 34
    • 84904977103 scopus 로고    scopus 로고
    • Composition and substrate-dependent strength of the silken attachment discs in spiders
    • Grawe, I., Wolff, J. O., and Gorb, S. N. (2014). Composition and substrate-dependent strength of the silken attachment discs in spiders. J. R. Soc. Interface R. Soc. 11:0477. doi: 10.1098/rsif.2014.0477
    • (2014) J. R. Soc. Interface R. Soc , vol.11 , pp. 0477
    • Grawe, I.1    Wolff, J.O.2    Gorb, S.N.3
  • 35
    • 0036238911 scopus 로고    scopus 로고
    • Developments in the area of bioadhesive drug delivery systems
    • Haas, J., and Lehr, C.-M. (2002). Developments in the area of bioadhesive drug delivery systems. Expert Opin. Biol. Ther. 2, 287-298. doi: 10.1517/14712598.2.3.287
    • (2002) Expert Opin. Biol. Ther , vol.2 , pp. 287-298
    • Haas, J.1    Lehr, C.-M.2
  • 37
    • 84931058745 scopus 로고    scopus 로고
    • Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue
    • Hua, S., Marks, E., Schneider, J. J., and Keely, S. (2015). Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue. Nanomedicine Nanotechnol. Biol. Med. 11, 1117-1132. doi: 10.1016/j.nano.2015.02.018
    • (2015) Nanomedicine Nanotechnol. Biol. Med , vol.11 , pp. 1117-1132
    • Hua, S.1    Marks, E.2    Schneider, J.J.3    Keely, S.4
  • 38
    • 29444456462 scopus 로고    scopus 로고
    • Tensile behavior and morphology of differently degummed silkworm (Bombyx mori) cocoon silk fibres
    • Jiang, P., Liu, H., Wang, C., Wu, L., Huang, J., and Guo, C. (2006). Tensile behavior and morphology of differently degummed silkworm (Bombyx mori) cocoon silk fibres. Mater. Lett. 60, 919-925. doi: 10.1016/j.matlet.2005.10.056
    • (2006) Mater. Lett , vol.60 , pp. 919-925
    • Jiang, P.1    Liu, H.2    Wang, C.3    Wu, L.4    Huang, J.5    Guo, C.6
  • 39
    • 84927948713 scopus 로고    scopus 로고
    • More than just fibers: an aqueous method for the production of innovative recombinant spider silk protein materials
    • Jones, J. A., Harris, T. I., Tucker, C. L., Berg, K. R., Christy, S. Y., Day, B. A., et al. (2015). More than just fibers: an aqueous method for the production of innovative recombinant spider silk protein materials. Biomacromolecules 16, 1418-1425. doi: 10.1021/acs.biomac.5b00226
    • (2015) Biomacromolecules , vol.16 , pp. 1418-1425
    • Jones, J.A.1    Harris, T.I.2    Tucker, C.L.3    Berg, K.R.4    Christy, S.Y.5    Day, B.A.6
  • 40
    • 34547666981 scopus 로고    scopus 로고
    • Matrix properties of a new plant gum in controlled drug delivery
    • Kalu, V., Odeniyi, M., and Jaiyeoba, K. (2007). Matrix properties of a new plant gum in controlled drug delivery. Arch. Pharm. Res. 30, 884-889. doi: 10.1007/BF02978841
    • (2007) Arch. Pharm. Res , vol.30 , pp. 884-889
    • Kalu, V.1    Odeniyi, M.2    Jaiyeoba, K.3
  • 41
    • 75149147526 scopus 로고    scopus 로고
    • Biodegradation, biodistribution and toxicity of chitosan
    • Kean, T., and Thanou, M. (2010). Biodegradation, biodistribution and toxicity of chitosan. Adv. Drug Deliv. Rev. 62, 3-11. doi: 10.1016/j.addr.2009.09.004
    • (2010) Adv. Drug Deliv. Rev , vol.62 , pp. 3-11
    • Kean, T.1    Thanou, M.2
  • 42
    • 82255192455 scopus 로고    scopus 로고
    • Preparation and evaluation of algino-sericin mucoadhesive microspheres: An approach for sustained drug delivery
    • Khandai, M., Chakraborty, S., Sharma, A., Pattnaik, S., Patra, C. N., Dinda, S. C., et al. (2010). Preparation and evaluation of algino-sericin mucoadhesive microspheres: An approach for sustained drug delivery. J. Adv. Pharm. Res. 1, 48-60.
    • (2010) J. Adv. Pharm. Res , vol.1 , pp. 48-60
    • Khandai, M.1    Chakraborty, S.2    Sharma, A.3    Pattnaik, S.4    Patra, C.N.5    Dinda, S.C.6
  • 43
    • 79958174556 scopus 로고    scopus 로고
    • Advances in mucoadhesion and mucoadhesive polymers
    • Khutoryanskiy, V. V. (2011). Advances in mucoadhesion and mucoadhesive polymers. Macromol. Biosci. 11, 748-764. doi: 10.1002/mabi.201000388
    • (2011) Macromol. Biosci , vol.11 , pp. 748-764
    • Khutoryanskiy, V.V.1
  • 44
    • 84932608602 scopus 로고    scopus 로고
    • Chitosan-catechol: a polymer with long-lasting mucoadhesive properties
    • Kim, K., Kim, K., Ryu, J. H., and Lee, H. (2015). Chitosan-catechol: a polymer with long-lasting mucoadhesive properties. Biomaterials 52, 161-170. doi: 10.1016/j.biomaterials.2015.02.010
    • (2015) Biomaterials , vol.52 , pp. 161-170
    • Kim, K.1    Kim, K.2    Ryu, J.H.3    Lee, H.4
  • 45
    • 56249122259 scopus 로고    scopus 로고
    • Design, fabrication and characterization of silk fibroin-HPMC-PEG blended films as vehicle for transmucosal delivery
    • Kundu, J., Patra, C., and Kundu, S. C. (2008a). Design, fabrication and characterization of silk fibroin-HPMC-PEG blended films as vehicle for transmucosal delivery. Mater. Sci. Eng. C 28, 1376-1380. doi: 10.1016/j.msec.2008.03.004
    • (2008) Mater. Sci. Eng. C , vol.28 , pp. 1376-1380
    • Kundu, J.1    Patra, C.2    Kundu, S.C.3
  • 46
    • 55649095103 scopus 로고    scopus 로고
    • Natural protective glue protein, sericin bioengineered by silkworms: potential for biomedical and biotechnological applications
    • Kundu, S. C., Dash, B. C., Dash, R., and Kaplan, D. L. (2008b). Natural protective glue protein, sericin bioengineered by silkworms: potential for biomedical and biotechnological applications. Prog. Polym. Sci. 33, 998-1012. doi: 10.1016/j.progpolymsci.2008.08.002
    • (2008) Prog. Polym. Sci , vol.33 , pp. 998-1012
    • Kundu, S.C.1    Dash, B.C.2    Dash, R.3    Kaplan, D.L.4
  • 47
    • 77950065443 scopus 로고    scopus 로고
    • Controlling silk fibroin particle features for drug delivery
    • Lammel, A. S., Hu, X., Park, S. H., Kaplan, D. L., and Scheibel, T. R. (2010). Controlling silk fibroin particle features for drug delivery. Biomaterials 31, 4583-4591. doi: 10.1016/j.biomaterials.2010.02.024
    • (2010) Biomaterials , vol.31 , pp. 4583-4591
    • Lammel, A.S.1    Hu, X.2    Park, S.H.3    Kaplan, D.L.4    Scheibel, T.R.5
  • 48
    • 84940491257 scopus 로고    scopus 로고
    • Toughened hydrogels inspired by aquatic caddisworm silk
    • Lane, D. D., Kaur, S., Weerasakare, G. M., and Stewart, R. J. (2015). Toughened hydrogels inspired by aquatic caddisworm silk. Soft Matter 11, 6981-6990. doi: 10.1039/C5SM01297J
    • (2015) Soft Matter , vol.11 , pp. 6981-6990
    • Lane, D.D.1    Kaur, S.2    Weerasakare, G.M.3    Stewart, R.J.4
  • 49
    • 0036737899 scopus 로고    scopus 로고
    • Synthesis and Gelation of DOPA-Modified Poly(ethylene glycol) Hydrogels
    • Lee, B. P., Dalsin, J. L., and Messersmith, P. B. (2002). Synthesis and Gelation of DOPA-Modified Poly(ethylene glycol) Hydrogels. Biomacromolecules 3, 1038-1047. doi: 10.1021/bm025546n
    • (2002) Biomacromolecules , vol.3 , pp. 1038-1047
    • Lee, B.P.1    Dalsin, J.L.2    Messersmith, P.B.3
  • 50
    • 77952726432 scopus 로고    scopus 로고
    • Biomaterials: intelligent glue
    • Lee, H. (2010). Biomaterials: intelligent glue. Nature 465, 298-299. doi: 10.1038/465298a
    • (2010) Nature , vol.465 , pp. 298-299
    • Lee, H.1
  • 51
    • 0033996243 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: the second generation of bioadhesives
    • Lehr, C. M. (2000). Lectin-mediated drug delivery: the second generation of bioadhesives. J. Control. Release Off. J. Control. Release Soc. 65, 19-29. doi: 10.1016/S0168-3659(99)00228-X
    • (2000) J. Control. Release Off. J. Control. Release Soc , vol.65 , pp. 19-29
    • Lehr, C.M.1
  • 52
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
    • Lehr, C.-M., Bouwstra, J. A., Schacht, E. H., and Junginger, H. E. (1992). In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int. J. Pharm. 78, 43-48. doi: 10.1016/0378-5173(92)90353-4
    • (1992) Int. J. Pharm , vol.78 , pp. 43-48
    • Lehr, C.-M.1    Bouwstra, J.A.2    Schacht, E.H.3    Junginger, H.E.4
  • 53
    • 0035998953 scopus 로고    scopus 로고
    • Physical characterization of a chitosan-based hydrogel delivery system
    • Li, J., and Xu, Z. (2002). Physical characterization of a chitosan-based hydrogel delivery system. J. Pharm. Sci. 91, 1669-1677. doi: 10.1002/jps.10157
    • (2002) J. Pharm. Sci , vol.91 , pp. 1669-1677
    • Li, J.1    Xu, Z.2
  • 54
    • 26644437438 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in ocular drug delivery
    • Ludwig, A. (2005). The use of mucoadhesive polymers in ocular drug delivery. Adv. Drug Deliv. Rev. 57, 1595-1639. doi: 10.1016/j.addr.2005.07.005
    • (2005) Adv. Drug Deliv. Rev , vol.57 , pp. 1595-1639
    • Ludwig, A.1
  • 55
    • 0003855045 scopus 로고
    • 'Mucus physiology and pathology, '
    • eds V. Lanaerts and R. Gurny (Florida, IL: CRC Press)
    • Marriott, C., and Gregory, N. (1990). "Mucus physiology and pathology, "in Bioadhesive Drug Delivery Systems, eds V. Lanaerts and R. Gurny (Florida, IL: CRC Press), 1-24.
    • (1990) Bioadhesive Drug Delivery Systems , pp. 1-24
    • Marriott, C.1    Gregory, N.2
  • 57
    • 0021722041 scopus 로고
    • Powder dosage form of insulin for nasal administration
    • Nagai, T., Yuji, N., Naoki, N., Yoshiki, S., and Kunio, S. (1984). Powder dosage form of insulin for nasal administration. J. Controlled Release 1, 15-22. doi: 10.1016/0168-3659(84)90017-8
    • (1984) J. Controlled Release , vol.1 , pp. 15-22
    • Nagai, T.1    Yuji, N.2    Naoki, N.3    Yoshiki, S.4    Kunio, S.5
  • 58
    • 84901983639 scopus 로고    scopus 로고
    • Naturapolyceutics: the science of utilizing natural polymers for drug delivery
    • Ngwuluka, N., Ochekpe, N., and Aruoma, O. (2014). Naturapolyceutics: the science of utilizing natural polymers for drug delivery. Polymers 6, 1312-1332. doi: 10.3390/polym6051312
    • (2014) Polymers , vol.6 , pp. 1312-1332
    • Ngwuluka, N.1    Ochekpe, N.2    Aruoma, O.3
  • 59
    • 84876324106 scopus 로고    scopus 로고
    • Long-range periodic sequence of the cement/silk protein of Stenopsyche marmorata: purification and biochemical characterisation
    • Ohkawa, K., Miura, Y., Nomura, T., Arai, R., Abe, K., Tsukada, M., et al. (2013). Long-range periodic sequence of the cement/silk protein of Stenopsyche marmorata: purification and biochemical characterisation. Biofouling 29, 357-367. doi: 10.1080/08927014.2013.774376
    • (2013) Biofouling , vol.29 , pp. 357-367
    • Ohkawa, K.1    Miura, Y.2    Nomura, T.3    Arai, R.4    Abe, K.5    Tsukada, M.6
  • 60
    • 69549086908 scopus 로고    scopus 로고
    • The adhesive delivery system of viscous capture threads spun by orb-weaving spiders
    • Opell, B. D., and Hendricks, M. L. (2009). The adhesive delivery system of viscous capture threads spun by orb-weaving spiders. J. Exp. Biol. 212, 3026-3034. doi: 10.1242/jeb.030064
    • (2009) J. Exp. Biol , vol.212 , pp. 3026-3034
    • Opell, B.D.1    Hendricks, M.L.2
  • 61
    • 84881181385 scopus 로고    scopus 로고
    • Environmental response and adaptation of glycoprotein glue within the droplets of viscous prey capture threads from araneoid spider orb-webs
    • Opell, B. D., Karinshak, S. E., and Sigler, M. A. (2013). Environmental response and adaptation of glycoprotein glue within the droplets of viscous prey capture threads from araneoid spider orb-webs. J. Exp. Biol. 216, 3023-3034. doi: 10.1242/jeb.084822
    • (2013) J. Exp. Biol , vol.216 , pp. 3023-3034
    • Opell, B.D.1    Karinshak, S.E.2    Sigler, M.A.3
  • 63
    • 84974825338 scopus 로고    scopus 로고
    • Biocompatibility of chitosan carriers with application in drug delivery
    • Rodrigues, S., Dionísio, M., López, C. R., and Grenha, A. (2012). Biocompatibility of chitosan carriers with application in drug delivery. J. Funct. Biomater. 3, 615-641. doi: 10.3390/jfb3030615
    • (2012) J. Funct. Biomater , vol.3 , pp. 615-641
    • Rodrigues, S.1    Dionísio, M.2    López, C.R.3    Grenha, A.4
  • 64
    • 78650407788 scopus 로고    scopus 로고
    • Viscoelastic solids explain spider web stickiness
    • Sahni, V., Blackledge, T. A., and Dhinojwala, A. (2010). Viscoelastic solids explain spider web stickiness. Nat. Commun. 1, 1-4. doi: 10.1038/ncomms1019
    • (2010) Nat. Commun , vol.1 , pp. 1-4
    • Sahni, V.1    Blackledge, T.A.2    Dhinojwala, A.3
  • 65
    • 79958858370 scopus 로고    scopus 로고
    • A review on spider silk adhesion
    • Sahni, V., Blackledge, T. A., and Dhinojwala, A. (2011). A review on spider silk adhesion. J. Adhes. 87, 595-614. doi: 10.1080/00218464.2011.583588
    • (2011) J. Adhes , vol.87 , pp. 595-614
    • Sahni, V.1    Blackledge, T.A.2    Dhinojwala, A.3
  • 66
    • 84898623950 scopus 로고    scopus 로고
    • Direct solvation of glycoproteins by salts in spider silk glues enhances adhesion and helps to explain the evolution of modern spider orb webs
    • Sahni, V., Miyoshi, T., Chen, K., Jain, D., Blamires, S. J., Blackledge, T. A., et al. (2014). Direct solvation of glycoproteins by salts in spider silk glues enhances adhesion and helps to explain the evolution of modern spider orb webs. Biomacromolecules 15, 1225-1232. doi: 10.1021/bm401800y
    • (2014) Biomacromolecules , vol.15 , pp. 1225-1232
    • Sahni, V.1    Miyoshi, T.2    Chen, K.3    Jain, D.4    Blamires, S.J.5    Blackledge, T.A.6
  • 67
    • 26644444777 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in buccal drug delivery
    • Salamat-Miller, N., Chittchang, M., and Johnston, T. (2005). The use of mucoadhesive polymers in buccal drug delivery. Adv. Drug Deliv. Rev. 57, 1666-1691. doi: 10.1016/j.addr.2005.07.003
    • (2005) Adv. Drug Deliv. Rev , vol.57 , pp. 1666-1691
    • Salamat-Miller, N.1    Chittchang, M.2    Johnston, T.3
  • 68
    • 80051475294 scopus 로고    scopus 로고
    • Silk fibroin and polyethylene glycol-based biocompatible tissue adhesives
    • Serban, M. A., Panilaitis, B., and Kaplan, D. L. (2011). Silk fibroin and polyethylene glycol-based biocompatible tissue adhesives. J. Biomed. Mater. Res. A 98A, 567-575. doi: 10.1002/jbm.a.33149
    • (2011) J. Biomed. Mater. Res. A , vol.98A , pp. 567-575
    • Serban, M.A.1    Panilaitis, B.2    Kaplan, D.L.3
  • 69
    • 0032215652 scopus 로고    scopus 로고
    • The microbial degradation of silk: a laboratory investigation
    • Seves, A., Romanò, M., Maifreni, T., Sora, S., and Ciferri, O. (1998). The microbial degradation of silk: a laboratory investigation. Int. Biodeterior. Biodegrad. 42, 203-211. doi: 10.1016/S0964-8305(98)00050-X
    • (1998) Int. Biodeterior. Biodegrad , vol.42 , pp. 203-211
    • Seves, A.1    Romanò, M.2    Maifreni, T.3    Sora, S.4    Ciferri, O.5
  • 71
    • 26644454810 scopus 로고    scopus 로고
    • The basics and underlying mechanisms of mucoadhesion
    • Smart, J. D. (2005). The basics and underlying mechanisms of mucoadhesion. Adv. Drug Deliv. Rev. 57, 1556-1568. doi: 10.1016/j.addr.2005.07.001
    • (2005) Adv. Drug Deliv. Rev , vol.57 , pp. 1556-1568
    • Smart, J.D.1
  • 73
    • 77950845516 scopus 로고    scopus 로고
    • Adaptation of caddisfly larval silks to aquatic habitats by phosphorylation of H-fibroin serines
    • Stewart, R. J., and Wang, C. S. (2010). Adaptation of caddisfly larval silks to aquatic habitats by phosphorylation of H-fibroin serines. Biomacromolecules 11, 969-974. doi: 10.1021/bm901426d
    • (2010) Biomacromolecules , vol.11 , pp. 969-974
    • Stewart, R.J.1    Wang, C.S.2
  • 74
    • 84855230248 scopus 로고    scopus 로고
    • Mucoadhesive drug delivery: mechanism and methods of evaluation
    • Tangri, P. (2011). Mucoadhesive drug delivery: mechanism and methods of evaluation. Int. J. Pharma Bio Sci. 2, 458-467.
    • (2011) Int. J. Pharma Bio Sci , vol.2 , pp. 458-467
    • Tangri, P.1
  • 75
    • 22944481530 scopus 로고    scopus 로고
    • Molecular orientation behavior of silk sericin film as revealed by ATR infrared spectroscopy
    • Teramoto, H., and Miyazawa, M. (2005). Molecular orientation behavior of silk sericin film as revealed by ATR infrared spectroscopy. Biomacromolecules 6, 2049-2057. doi: 10.1021/bm0500547
    • (2005) Biomacromolecules , vol.6 , pp. 2049-2057
    • Teramoto, H.1    Miyazawa, M.2
  • 77
    • 84889091258 scopus 로고    scopus 로고
    • Physical characterization of the liquid adhesive from orb-weaving spiders
    • Torres, F. G., Troncoso, O. P., and Cavalie, F. (2014). Physical characterization of the liquid adhesive from orb-weaving spiders. Mater. Sci. Eng. C 34, 341-344. doi: 10.1016/j.msec.2013.09.030
    • (2014) Mater. Sci. Eng. C , vol.34 , pp. 341-344
    • Torres, F.G.1    Troncoso, O.P.2    Cavalie, F.3
  • 78
    • 26844560127 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in vaginal delivery
    • Valenta, C. (2005). The use of mucoadhesive polymers in vaginal delivery. Adv. Drug Deliv. Rev. 57, 1692-1712. doi: 10.1016/j.addr.2005.07.004
    • (2005) Adv. Drug Deliv. Rev , vol.57 , pp. 1692-1712
    • Valenta, C.1
  • 79
    • 84867824150 scopus 로고    scopus 로고
    • Spider glue proteins have distinct architectures compared with traditional spidroin family members
    • Vasanthavada, K., Hu, X., Tuton-Blasingame, T., Hsia, Y., Sampath, S., Pacheco, R., et al. (2012). Spider glue proteins have distinct architectures compared with traditional spidroin family members. J. Biol. Chem. 287, 35986-35999. doi: 10.1074/jbc.M112.399816
    • (2012) J. Biol. Chem , vol.287 , pp. 35986-35999
    • Vasanthavada, K.1    Hu, X.2    Tuton-Blasingame, T.3    Hsia, Y.4    Sampath, S.5    Pacheco, R.6
  • 80
    • 74049159523 scopus 로고    scopus 로고
    • A novel bioadhesive protein of silk filaments spun underwater by caddisfly larvae
    • Wang, Y. J., Sanai, K., and Nakagaki, M. (2009). A novel bioadhesive protein of silk filaments spun underwater by caddisfly larvae. Adv. Mater. Res. 79-82, 1631-1634. doi: 10.4028/www.scientific.net/AMR.79-82.1631
    • (2009) Adv. Mater. Res , vol.79-82 , pp. 1631-1634
    • Wang, Y.J.1    Sanai, K.2    Nakagaki, M.3
  • 81
    • 33645037223 scopus 로고    scopus 로고
    • Preparation and in vitro evaluation of mucoadhesive properties of alginate/chitosan microparticles containing prednisolone
    • Wittaya-areekul, S., Kruenate, J., and Prahsarn, C. (2006). Preparation and in vitro evaluation of mucoadhesive properties of alginate/chitosan microparticles containing prednisolone. Int. J. Pharm. 312, 113-118. doi: 10.1016/j.ijpharm.2006.01.003
    • (2006) Int. J. Pharm , vol.312 , pp. 113-118
    • Wittaya-areekul, S.1    Kruenate, J.2    Prahsarn, C.3
  • 82
    • 84889090957 scopus 로고    scopus 로고
    • Assessment of test methods evaluating mucoadhesive polymers and dosage forms: an overview
    • Woertz, C., Preis, M., Breitkreutz, J., and Kleinebudde, P. (2013). Assessment of test methods evaluating mucoadhesive polymers and dosage forms: an overview. Eur. J. Pharm. Biopharm. 85, 843-853. doi: 10.1016/j.ejpb.2013.06.023
    • (2013) Eur. J. Pharm. Biopharm , vol.85 , pp. 843-853
    • Woertz, C.1    Preis, M.2    Breitkreutz, J.3    Kleinebudde, P.4
  • 83
    • 84924859502 scopus 로고    scopus 로고
    • Spider's super-glue: thread anchors are composite adhesives with synergistic hierarchical organization
    • Wolff, J. O., Grawe, I., Wirth, M., Karstedt, A., and Gorb, S. N. (2015). Spider's super-glue: thread anchors are composite adhesives with synergistic hierarchical organization. Soft Matter 11, 2394-2403. doi: 10.1039/C4SM02130D
    • (2015) Soft Matter , vol.11 , pp. 2394-2403
    • Wolff, J.O.1    Grawe, I.2    Wirth, M.3    Karstedt, A.4    Gorb, S.N.5
  • 84
    • 0035068551 scopus 로고    scopus 로고
    • Bioadhesion: new possibilities for drug administration?
    • Woodley, J. (2001). Bioadhesion: new possibilities for drug administration? Clin. Pharmacokinet. 40, 77-84. doi: 10.2165/00003088-200140020-00001
    • (2001) Clin. Pharmacokinet , vol.40 , pp. 77-84
    • Woodley, J.1
  • 85
    • 84867063855 scopus 로고    scopus 로고
    • Mollusk glue inspired mucoadhesives for biomedical applications
    • Xu, J., Soliman, G. M., Barralet, J., and Cerruti, M. (2012). Mollusk glue inspired mucoadhesives for biomedical applications. Langmuir 28, 14010-14017. doi: 10.1021/la3025414
    • (2012) Langmuir , vol.28 , pp. 14010-14017
    • Xu, J.1    Soliman, G.M.2    Barralet, J.3    Cerruti, M.4
  • 86
    • 79961237547 scopus 로고    scopus 로고
    • Mucoadhesive polymers: means of improving the mucoadhesion properties of drug delivery system
    • Yadav, V. K., Gupta, A. B., Kumar, R., Yadev, J. S., and Kumar, B. (2010). Mucoadhesive polymers: means of improving the mucoadhesion properties of drug delivery system. J. Chem. Pharm. Res. 2, 418-432.
    • (2010) J. Chem. Pharm. Res , vol.2 , pp. 418-432
    • Yadav, V.K.1    Gupta, A.B.2    Kumar, R.3    Yadev, J.S.4    Kumar, B.5
  • 87
    • 84930017783 scopus 로고    scopus 로고
    • "Mucoadhesion and characterization of mucoadhesive properties, "
    • eds J. das Neves and B. Sarmento (Boston, MA: Springer US) [Accessed August 4, 2015]
    • Yu, T., Andrews, G. P., and Jones, D. S. (2014). "Mucoadhesion and characterization of mucoadhesive properties, "in Mucosal Delivery of Biopharmaceuticals, eds J. das Neves and B. Sarmento (Boston, MA: Springer US), 35-58. Available at: http://link.springer.com/10.1007/978-1-4614-9524-6_2 [Accessed August 4, 2015].
    • (2014) Mucosal Delivery of Biopharmaceuticals , pp. 35-58
    • Yu, T.1    Andrews, G.P.2    Jones, D.S.3
  • 88
    • 77951976607 scopus 로고    scopus 로고
    • Non-equilibrium silk fibroin adhesives
    • Yucel, T., Kojic, N., Leisk, G. G., Lo, T. J., and Kaplan, D. L. (2010). Non-equilibrium silk fibroin adhesives. J. Struct. Biol. 170, 406-412. doi: 10.1016/j.jsb.2009.12.012
    • (2010) J. Struct. Biol , vol.170 , pp. 406-412
    • Yucel, T.1    Kojic, N.2    Leisk, G.G.3    Lo, T.J.4    Kaplan, D.L.5
  • 89
    • 0036268771 scopus 로고    scopus 로고
    • Applications of natural silk protein sericin in biomaterials
    • Zhang, Y.Q. (2002). Applications of natural silk protein sericin in biomaterials. Biotechnol. Adv. 20, 91-100. doi: 10.1016/S0734-9750(02)00003-4
    • (2002) Biotechnol. Adv , vol.20 , pp. 91-100
    • Zhang, Y.Q.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.