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Volumn 85, Issue 3 PART B, 2013, Pages 843-853

Assessment of test methods evaluating mucoadhesive polymers and dosage forms: An overview

Author keywords

Mucoadhesion; Mucoadhesive preparation; Oral mucosa; Oromucosal preparation; Polymer; Texture Analyser

Indexed keywords

ALGINIC ACID; CARBOMER; CARBOXYMETHYLCELLULOSE; CHITOSAN; COLLOIDAL GOLD; GELATIN; GLYCEROL; HYALURONIC ACID; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL 6000; MUCIN; OXYCODONE; PECTIN; POLY(METHYL METHACRYLATE); POLYACRYLIC ACID; POLYETHYLENE; POLYETHYLENE TEREPHTHALATE; POLYMER; POVIDONE; SILICATE; SILICON DIOXIDE; SORBITOL; STAINLESS STEEL;

EID: 84889090957     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.06.023     Document Type: Review
Times cited : (106)

References (87)
  • 1
    • 0030208529 scopus 로고    scopus 로고
    • Hydrogels as mucoadhesive and bioadhesive materials: A review
    • N.A. Peppas, and J.J. Sahlin Hydrogels as mucoadhesive and bioadhesive materials: a review Biomaterials 17 1996 1553 1561
    • (1996) Biomaterials , vol.17 , pp. 1553-1561
    • Peppas, N.A.1    Sahlin, J.J.2
  • 2
    • 0022402037 scopus 로고
    • Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues
    • N.A. Peppas, and P.A. Buri Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues Journal of Controlled Release 2 1985 257 275
    • (1985) Journal of Controlled Release , vol.2 , pp. 257-275
    • Peppas, N.A.1    Buri, P.A.2
  • 3
    • 0028330603 scopus 로고
    • On the role of electrostatic forces in the adhesion of polymer particles to solid surfaces
    • B.V. Derjaguin, I.N. Aleinikova, and Y.P. Toporov On the role of electrostatic forces in the adhesion of polymer particles to solid surfaces Progress in Surface Science 45 1994 119 123
    • (1994) Progress in Surface Science , vol.45 , pp. 119-123
    • Derjaguin, B.V.1    Aleinikova, I.N.2    Toporov, Y.P.3
  • 4
    • 0019056719 scopus 로고
    • The science of adhesion - Part 1 Surface and interfacial aspects
    • A.J. Kinloch The science of adhesion - Part 1 Surface and interfacial aspects Journal of Materials Science 15 1980 2141 2166
    • (1980) Journal of Materials Science , vol.15 , pp. 2141-2166
    • Kinloch, A.J.1
  • 5
    • 0023235537 scopus 로고
    • Bioadhesive analysis of controlled-release systems. I. Fracture and interpenetration analysis in poly(acrylic acid)-containing systems
    • G. Ponchel, F. Touchard, D. Duchene, and N.A. Peppas Bioadhesive analysis of controlled-release systems. I. Fracture and interpenetration analysis in poly(acrylic acid)-containing systems Journal of Controlled Release 5 1987 129 141
    • (1987) Journal of Controlled Release , vol.5 , pp. 129-141
    • Ponchel, G.1    Touchard, F.2    Duchene, D.3    Peppas, N.A.4
  • 7
    • 0023892746 scopus 로고
    • Pharmaceutical and medical aspects of bioadhesive systems for drug administration
    • D. Duchene, F. Touchard, and N.A. Peppas Pharmaceutical and medical aspects of bioadhesive systems for drug administration Drug Development and Industrial Pharmacy 14 1988 283 318
    • (1988) Drug Development and Industrial Pharmacy , vol.14 , pp. 283-318
    • Duchene, D.1    Touchard, F.2    Peppas, N.A.3
  • 9
    • 0021344079 scopus 로고
    • Bioadhesive polymers as platforms for oral-controlled drug delivery: Method to study bioadhesion
    • K. Park, and J.R. Robinson Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion International Journal of Pharmaceutics 19 1984 107 127
    • (1984) International Journal of Pharmaceutics , vol.19 , pp. 107-127
    • Park, K.1    Robinson, J.R.2
  • 10
    • 0035678479 scopus 로고    scopus 로고
    • Interpretation of mucoadhesive properties of polymer gel preparations using a tensile strength method
    • H. Hägerström, and K. Edsman Interpretation of mucoadhesive properties of polymer gel preparations using a tensile strength method Journal of Pharmacy and Pharmacology 53 2001 1589 1599
    • (2001) Journal of Pharmacy and Pharmacology , vol.53 , pp. 1589-1599
    • Hägerström, H.1    Edsman, K.2
  • 11
    • 0030955984 scopus 로고    scopus 로고
    • Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers
    • D.S. Jones, A.D. Woolfson, and A.F. Brown Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers International Journal of Pharmaceutics 151 1997 223 233
    • (1997) International Journal of Pharmaceutics , vol.151 , pp. 223-233
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 12
    • 0021236615 scopus 로고
    • An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery
    • J.D. Smart, I.W. Kellaway, and H.E.C. Worthington An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery Journal of Pharmacy and Pharmacology 36 1984 295 299
    • (1984) Journal of Pharmacy and Pharmacology , vol.36 , pp. 295-299
    • Smart, J.D.1    Kellaway, I.W.2    Worthington, H.E.C.3
  • 13
    • 0021739215 scopus 로고
    • Bioadhesive intraoral release systems: Design, testing and analysis
    • R. Gurny, J.M. Meyer, and N.A. Peppas Bioadhesive intraoral release systems: design, testing and analysis Biomaterials 5 1984 336 340
    • (1984) Biomaterials , vol.5 , pp. 336-340
    • Gurny, R.1    Meyer, J.M.2    Peppas, N.A.3
  • 14
    • 80053611097 scopus 로고    scopus 로고
    • Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems
    • D.J. Hall, O.V. Khutoryanskaya, and V.V. Khutoryanskiy Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems Soft Matter 7 2011 9620 9623
    • (2011) Soft Matter , vol.7 , pp. 9620-9623
    • Hall, D.J.1    Khutoryanskaya, O.V.2    Khutoryanskiy, V.V.3
  • 15
    • 57349144982 scopus 로고    scopus 로고
    • Mucoadhesive drug delivery systems: Quantitative assessment of interaction between synthetic and natural polymer films and mucosa
    • E.A. Kharenko, N.I. Larionova, and N.B. Demina Mucoadhesive drug delivery systems: quantitative assessment of interaction between synthetic and natural polymer films and mucosa Pharmaceutical Chemistry Journal 42 2008 392 399
    • (2008) Pharmaceutical Chemistry Journal , vol.42 , pp. 392-399
    • Kharenko, E.A.1    Larionova, N.I.2    Demina, N.B.3
  • 16
    • 0025108791 scopus 로고
    • A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength
    • E.E. Hassan, and J.M. Gallo A simple rheological method for the in vitro assessment of mucin-polymer bioadhesive bond strength Pharmaceutical Research 7 1990 491 495
    • (1990) Pharmaceutical Research , vol.7 , pp. 491-495
    • Hassan, E.E.1    Gallo, J.M.2
  • 17
    • 84856089110 scopus 로고    scopus 로고
    • Comparison of in vitro methods of measuring mucoadhesion: Ellipsometry, tensile strength and rheological measurements
    • D. Ivarsson, and M. Wahlgren Comparison of in vitro methods of measuring mucoadhesion: ellipsometry, tensile strength and rheological measurements Colloids and Surfaces B: Biointerfaces 92 2012 353 359
    • (2012) Colloids and Surfaces B: Biointerfaces , vol.92 , pp. 353-359
    • Ivarsson, D.1    Wahlgren, M.2
  • 18
    • 0025355398 scopus 로고
    • Bioadhesive analysis of controlled-release systems. IV. An experimental method for testing the adhesion of microparticles with mucus
    • A.G. Mikos, and N.A. Peppas Bioadhesive analysis of controlled-release systems. IV. An experimental method for testing the adhesion of microparticles with mucus Journal of Controlled Release 12 1990 31 37
    • (1990) Journal of Controlled Release , vol.12 , pp. 31-37
    • Mikos, A.G.1    Peppas, N.A.2
  • 20
    • 0022368327 scopus 로고
    • Physico-chemical properties of water insoluble polymers important to mucin/epithelial adhesion
    • H. Park, and J.R. Robinson Physico-chemical properties of water insoluble polymers important to mucin/epithelial adhesion Journal of Controlled Release 2 1985 47 57
    • (1985) Journal of Controlled Release , vol.2 , pp. 47-57
    • Park, H.1    Robinson, J.R.2
  • 21
  • 24
    • 0034892282 scopus 로고    scopus 로고
    • In vitro assessment of the mucoadhesion of cholestyramine to porcine and human gastric mucosa
    • S.J. Jackson, and A.C. Perkins In vitro assessment of the mucoadhesion of cholestyramine to porcine and human gastric mucosa European Journal of Pharmaceutics and Biopharmaceutics 52 2001 121 127
    • (2001) European Journal of Pharmaceutics and Biopharmaceutics , vol.52 , pp. 121-127
    • Jackson, S.J.1    Perkins, A.C.2
  • 26
    • 0034925740 scopus 로고    scopus 로고
    • Thiolated polymers - Thiomers: Development and in vitro evaluation of chitosan-thioglycolic acid conjugates
    • C.E. Kast, and A. Bernkop-Schnürch Thiolated polymers - thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates Biomaterials 22 2001 2345 2352
    • (2001) Biomaterials , vol.22 , pp. 2345-2352
    • Kast, C.E.1    Bernkop-Schnürch, A.2
  • 27
    • 0025738301 scopus 로고
    • An in vitro assessment of some mucosa-adhesive dosage forms
    • J.D. Smart An in vitro assessment of some mucosa-adhesive dosage forms International Journal of Pharmaceutics 73 1991 69 74
    • (1991) International Journal of Pharmaceutics , vol.73 , pp. 69-74
    • Smart, J.D.1
  • 30
    • 0142245748 scopus 로고    scopus 로고
    • Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride
    • N.A. Nafee, N.A. Boraie, F.A. Ismail, and L.M. Mortada Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride Acta Pharmaceutica 53 2003 199 212
    • (2003) Acta Pharmaceutica , vol.53 , pp. 199-212
    • Nafee, N.A.1    Boraie, N.A.2    Ismail, F.A.3    Mortada, L.M.4
  • 31
  • 32
    • 0024552779 scopus 로고
    • Evaluation of laminated muco-adhesive patches for buccal drug delivery
    • R. Anders, and H.P. Merkle Evaluation of laminated muco-adhesive patches for buccal drug delivery International Journal of Pharmaceutics 49 1989 231 240
    • (1989) International Journal of Pharmaceutics , vol.49 , pp. 231-240
    • Anders, R.1    Merkle, H.P.2
  • 35
    • 67349189475 scopus 로고    scopus 로고
    • Evaluating the mucoadhesive properties of drug delivery systems based on hydrated thiolated alginate
    • M. Davidovich-Pinhas, O. Harari, and H. Bianco-Peled Evaluating the mucoadhesive properties of drug delivery systems based on hydrated thiolated alginate Journal of Controlled Release 136 2009 38 44
    • (2009) Journal of Controlled Release , vol.136 , pp. 38-44
    • Davidovich-Pinhas, M.1    Harari, O.2    Bianco-Peled, H.3
  • 36
    • 0344519699 scopus 로고    scopus 로고
    • An in vitro investigation for vaginal bioadhesive formulations: Bioadhesive properties and swelling states of polymer mixtures
    • E. BaloÇlu, M. Özyazici, S.Y. HizarcioÇlu, and H.A. Karavana An in vitro investigation for vaginal bioadhesive formulations: bioadhesive properties and swelling states of polymer mixtures Farmaco 58 2003 391 396
    • (2003) Farmaco , vol.58 , pp. 391-396
    • Baloçlu, E.1    Özyazici, M.2    Hizarcioçlu, S.Y.3    Karavana, H.A.4
  • 37
    • 0023637722 scopus 로고
    • Bioadhesive analysis of controlled-release systems. III. Bioadhesive and release behavior of metronidazole-containing poly(acrylic acid)-hydroxypropyl methylcellulose systems
    • G. Ponchel, F. Touchard, D. Wouessidjewe, D. Duchene, and N.A. Peppas Bioadhesive analysis of controlled-release systems. III. Bioadhesive and release behavior of metronidazole-containing poly(acrylic acid)-hydroxypropyl methylcellulose systems International Journal of Pharmaceutics 38 1987 65 70
    • (1987) International Journal of Pharmaceutics , vol.38 , pp. 65-70
    • Ponchel, G.1    Touchard, F.2    Wouessidjewe, D.3    Duchene, D.4    Peppas, N.A.5
  • 38
    • 0030068897 scopus 로고    scopus 로고
    • Design and evaluation of sustained-release and buccal adhesive propranolol hydrochloride tablets
    • B. Taylan, Y. Capan, O. Güven, S. Kes, and A.A. Hincal Design and evaluation of sustained-release and buccal adhesive propranolol hydrochloride tablets Journal of Controlled Release 38 1996 11 20
    • (1996) Journal of Controlled Release , vol.38 , pp. 11-20
    • Taylan, B.1    Capan, Y.2    Güven, O.3    Kes, S.4    Hincal, A.A.5
  • 40
    • 33746468534 scopus 로고    scopus 로고
    • Buccal bioadhesive drug delivery - A promising option for orally less efficient drugs
    • Y. Sudhakar, K. Kuotsu, and A.K. Bandyopadhyay Buccal bioadhesive drug delivery - a promising option for orally less efficient drugs Journal of Controlled Release 114 2006 15 40
    • (2006) Journal of Controlled Release , vol.114 , pp. 15-40
    • Sudhakar, Y.1    Kuotsu, K.2    Bandyopadhyay, A.K.3
  • 42
    • 8344252009 scopus 로고    scopus 로고
    • Adhesion of polyether-modified poly(acrylic acid) to mucin
    • J. Cleary, L. Bromberg, and E. Magner Adhesion of polyether-modified poly(acrylic acid) to mucin Langmuir 20 2004 9755 9762
    • (2004) Langmuir , vol.20 , pp. 9755-9762
    • Cleary, J.1    Bromberg, L.2    Magner, E.3
  • 43
  • 44
    • 40849136145 scopus 로고    scopus 로고
    • Evaluation of mucoadhesiveness of polymers by BIACORE method and mucin-particle method
    • J. Thongborisute, and H. Takeuchi Evaluation of mucoadhesiveness of polymers by BIACORE method and mucin-particle method International Journal of Pharmaceutics 354 2008 204 209
    • (2008) International Journal of Pharmaceutics , vol.354 , pp. 204-209
    • Thongborisute, J.1    Takeuchi, H.2
  • 46
    • 0000431772 scopus 로고
    • A new approach to study mucoadhesion: Colloidal gold staining
    • K. Park A new approach to study mucoadhesion: colloidal gold staining International Journal of Pharmaceutics 53 1989 209 217
    • (1989) International Journal of Pharmaceutics , vol.53 , pp. 209-217
    • Park, K.1
  • 47
    • 0023575329 scopus 로고
    • Mechanistic studies in the simultaneous flow and adsorption of polymer-coated latex particles on intestinal mucus I: Methods and physical model development
    • C.L.C. Teng, and N.F.H. Ho Mechanistic studies in the simultaneous flow and adsorption of polymer-coated latex particles on intestinal mucus I: methods and physical model development Journal of Controlled Release 6 1987 133 149
    • (1987) Journal of Controlled Release , vol.6 , pp. 133-149
    • Teng, C.L.C.1    Ho, N.F.H.2
  • 48
    • 0041967089 scopus 로고    scopus 로고
    • Mucoadhesive microspheres containing gentamicin sulfate for nasal administration: Preparation and in vitro characterization
    • C. Hasçiçek, N. Gönül, and N. Erk Mucoadhesive microspheres containing gentamicin sulfate for nasal administration: preparation and in vitro characterization Farmaco 58 2003 11 16
    • (2003) Farmaco , vol.58 , pp. 11-16
    • Hasçiçek, C.1    Gönül, N.2    Erk, N.3
  • 49
    • 0031713288 scopus 로고    scopus 로고
    • Bioadhesive drug delivery systems. I. Characterisation of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinoleate
    • L.S. Nielsen, L. Schubert, and J. Hansen Bioadhesive drug delivery systems. I. Characterisation of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinoleate European Journal of Pharmaceutical Sciences 6 1998 231 239
    • (1998) European Journal of Pharmaceutical Sciences , vol.6 , pp. 231-239
    • Nielsen, L.S.1    Schubert, L.2    Hansen, J.3
  • 52
    • 1242331449 scopus 로고    scopus 로고
    • The importance of gel properties for mucoadhesion measurements: A multivariate data analysis approach
    • H. Hägerström, C.A.S. Bergström, and K. Edsman The importance of gel properties for mucoadhesion measurements: a multivariate data analysis approach Journal of Pharmacy and Pharmacology 56 2004 161 168
    • (2004) Journal of Pharmacy and Pharmacology , vol.56 , pp. 161-168
    • Hägerström, H.1    Bergström, C.A.S.2    Edsman, K.3
  • 54
    • 83355163301 scopus 로고    scopus 로고
    • Mucoadhesive buccal patches based on interpolymer complexes of chitosan-pectin for delivery of carvedilol
    • A. Kaur, and G. Kaur Mucoadhesive buccal patches based on interpolymer complexes of chitosan-pectin for delivery of carvedilol Saudi Pharmaceutical Journal 20 2012 21 27
    • (2012) Saudi Pharmaceutical Journal , vol.20 , pp. 21-27
    • Kaur, A.1    Kaur, G.2
  • 55
    • 63649104404 scopus 로고    scopus 로고
    • Preparation, in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine
    • C. Juliano, M. Cossu, P. Pigozzi, G. Rassu, and P. Giunchedi Preparation, in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine AAPS PharmSciTech 9 2008 1153 1158
    • (2008) AAPS PharmSciTech , vol.9 , pp. 1153-1158
    • Juliano, C.1    Cossu, M.2    Pigozzi, P.3    Rassu, G.4    Giunchedi, P.5
  • 57
    • 61349119919 scopus 로고    scopus 로고
    • In vitro and ex vivo bioadhesivity analysis of polymeric intravaginal caplets using physicomechanics and computational structural modeling
    • V.M.K. Ndesendo, V. Pillay, Y.E. Choonara, R.A. Khan, L. Meyer, E. Buchmann, and U. Rosin In vitro and ex vivo bioadhesivity analysis of polymeric intravaginal caplets using physicomechanics and computational structural modeling International Journal of Pharmaceutics 370 2009 151 159
    • (2009) International Journal of Pharmaceutics , vol.370 , pp. 151-159
    • Ndesendo, V.M.K.1    Pillay, V.2    Choonara, Y.E.3    Khan, R.A.4    Meyer, L.5    Buchmann, E.6    Rosin, U.7
  • 58
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery II: Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers
    • H.S. Ch'ng, H. Park, P. Kelly, and J.R. Robinson Bioadhesive polymers as platforms for oral controlled drug delivery II: synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers Journal of Pharmaceutical Sciences 74 1985 399 405
    • (1985) Journal of Pharmaceutical Sciences , vol.74 , pp. 399-405
    • Ch'Ng, H.S.1    Park, H.2    Kelly, P.3    Robinson, J.R.4
  • 60
    • 0033123016 scopus 로고    scopus 로고
    • Polymeric films as vehicle for buccal delivery: Swelling, mechanical, and bioadhesive properties
    • K.K. Peh, and C.F. Wong Polymeric films as vehicle for buccal delivery: swelling, mechanical, and bioadhesive properties Journal of Pharmacy & Pharmaceutical Sciences 2 1999 53 61
    • (1999) Journal of Pharmacy & Pharmaceutical Sciences , vol.2 , pp. 53-61
    • Peh, K.K.1    Wong, C.F.2
  • 61
    • 0033006296 scopus 로고    scopus 로고
    • Formulation and evaluation of controlled release Eudragit buccal patches
    • C.F. Wong, K.H. Yuen, and K.K. Peh Formulation and evaluation of controlled release Eudragit buccal patches International Journal of Pharmaceutics 178 1999 11 22
    • (1999) International Journal of Pharmaceutics , vol.178 , pp. 11-22
    • Wong, C.F.1    Yuen, K.H.2    Peh, K.K.3
  • 62
    • 0026565713 scopus 로고
    • Mucoadhesion of both film-forming and non-film-forming polymeric materials as evaluated with the Wilhelmy plate method
    • A.P. Sam, J.T.M. van den Heuij, and J.J. Tukker Mucoadhesion of both film-forming and non-film-forming polymeric materials as evaluated with the Wilhelmy plate method International Journal of Pharmaceutics 79 1992 97 105
    • (1992) International Journal of Pharmaceutics , vol.79 , pp. 97-105
    • Sam, A.P.1    Van Den Heuij, J.T.M.2    Tukker, J.J.3
  • 63
    • 79957517835 scopus 로고    scopus 로고
    • Development and characterization of controlled release mucoadhesive tablets of captopril
    • H.P. Dalvadi, J.K. Patel, G.C. Rajput, V. Muruganantham, and B. Jayakar Development and characterization of controlled release mucoadhesive tablets of captopril Ars Pharmaceutica 52 2011 31 37
    • (2011) Ars Pharmaceutica , vol.52 , pp. 31-37
    • Dalvadi, H.P.1    Patel, J.K.2    Rajput, G.C.3    Muruganantham, V.4    Jayakar, B.5
  • 64
    • 0032529057 scopus 로고    scopus 로고
    • Histological and bioadhesion studies on buccal bioadhesive tablets containing a penetration enhancer sodium glycodeoxycholate
    • S. Şenel, Y. Çapan, M.F. Sargon, C.B. Giray, and A.A. Hincal Histological and bioadhesion studies on buccal bioadhesive tablets containing a penetration enhancer sodium glycodeoxycholate International Journal of Pharmaceutics 170 1998 239 245
    • (1998) International Journal of Pharmaceutics , vol.170 , pp. 239-245
    • Şenel, S.1    Çapan, Y.2    Sargon, M.F.3    Giray, C.B.4    Hincal, A.A.5
  • 66
    • 33947681178 scopus 로고    scopus 로고
    • Formulation, evaluation, and comparison of bilayered and multilayered mucoadhesive buccal devices of propranolol hydrochloride
    • V.M. Patel, B.G. Prajapati, and M.M. Patel Formulation, evaluation, and comparison of bilayered and multilayered mucoadhesive buccal devices of propranolol hydrochloride AAPS PharmSciTech 8 2007
    • (2007) AAPS PharmSciTech , vol.8
    • Patel, V.M.1    Prajapati, B.G.2    Patel, M.M.3
  • 67
    • 34548316348 scopus 로고    scopus 로고
    • Mucoadhesive dosage form of lidocaine hydrochloride: I. Mucoadhesive and physicochemical characterization
    • R. Abu-Huwaij, S. Assaf, M. Salem, and A. Sallam Mucoadhesive dosage form of lidocaine hydrochloride: I. Mucoadhesive and physicochemical characterization Drug Development and Industrial Pharmacy 33 2007 855 864
    • (2007) Drug Development and Industrial Pharmacy , vol.33 , pp. 855-864
    • Abu-Huwaij, R.1    Assaf, S.2    Salem, M.3    Sallam, A.4
  • 68
    • 0037712690 scopus 로고    scopus 로고
    • Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery
    • C. Remuñán-López, A. Portero, J.L. Vila-Jato, and M.J. Alonso Design and evaluation of chitosan/ethylcellulose mucoadhesive bilayered devices for buccal drug delivery Journal of Controlled Release 55 1998 143 152
    • (1998) Journal of Controlled Release , vol.55 , pp. 143-152
    • Remuñán-López, C.1    Portero, A.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 69
    • 0029901479 scopus 로고    scopus 로고
    • Characterization of mucin interaction with three viscosity grades of sodium carboxymethylcellulose. Comparison between rheological and tensile testing
    • S. Rossi, M.C. Bonferoni, F. Ferrari, M. Bertoni, and C. Caramella Characterization of mucin interaction with three viscosity grades of sodium carboxymethylcellulose. Comparison between rheological and tensile testing European Journal of Pharmaceutical Sciences 4 1996 189 196
    • (1996) European Journal of Pharmaceutical Sciences , vol.4 , pp. 189-196
    • Rossi, S.1    Bonferoni, M.C.2    Ferrari, F.3    Bertoni, M.4    Caramella, C.5
  • 71
    • 34249279844 scopus 로고    scopus 로고
    • In vitro measurements of mucoadhesive properties of six types of pectin
    • E. Hagesaether, and S.A. Sande In vitro measurements of mucoadhesive properties of six types of pectin Drug Development and Industrial Pharmacy 33 2007 417 425
    • (2007) Drug Development and Industrial Pharmacy , vol.33 , pp. 417-425
    • Hagesaether, E.1    Sande, S.A.2
  • 72
    • 0037241111 scopus 로고    scopus 로고
    • Mucoadhesive and cohesive properties of poly(acrylic acid)-cysteine conjugates with regard to their molecular mass
    • V.M. Leitner, M.K. Marschütz, and A. Bernkop-Schnürch Mucoadhesive and cohesive properties of poly(acrylic acid)-cysteine conjugates with regard to their molecular mass European Journal of Pharmaceutical Sciences 18 2003 89 96
    • (2003) European Journal of Pharmaceutical Sciences , vol.18 , pp. 89-96
    • Leitner, V.M.1    Marschütz, M.K.2    Bernkop-Schnürch, A.3
  • 73
    • 0029007380 scopus 로고
    • Bioadhesive microspheres: I. A novel electrobalance-based method to study adhesive interactions between individual microspheres and intestinal mucosa
    • D.E. Chickering, and E. Mathiowitz Bioadhesive microspheres: I. A novel electrobalance-based method to study adhesive interactions between individual microspheres and intestinal mucosa Journal of Controlled Release 34 1995 251 261
    • (1995) Journal of Controlled Release , vol.34 , pp. 251-261
    • Chickering, D.E.1    Mathiowitz, E.2
  • 75
    • 84855174405 scopus 로고    scopus 로고
    • Development and evaluation of mucoadhesive buccal patches of flurbiprofen
    • S.K. Mishra, N. Garud, and R. Singh Development and evaluation of mucoadhesive buccal patches of flurbiprofen Acta Poloniae Pharmaceutica 68 2011 955 964
    • (2011) Acta Poloniae Pharmaceutica , vol.68 , pp. 955-964
    • Mishra, S.K.1    Garud, N.2    Singh, R.3
  • 77
    • 0035999871 scopus 로고    scopus 로고
    • Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: Optimization of bioadhesion, dissolution, and diffusion parameters
    • B. Singh, and N. Ahuja Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: optimization of bioadhesion, dissolution, and diffusion parameters Drug Development and Industrial Pharmacy 28 2002 431 442
    • (2002) Drug Development and Industrial Pharmacy , vol.28 , pp. 431-442
    • Singh, B.1    Ahuja, N.2
  • 79
    • 23144451894 scopus 로고    scopus 로고
    • Preparation and evaluation of a novel buccal adhesive system
    • (electronic resource)
    • K.G. Desai, and T.M. Kumar Preparation and evaluation of a novel buccal adhesive system AAPS PharmSciTech 5 2004 (electronic resource)
    • (2004) AAPS PharmSciTech , vol.5
    • Desai, K.G.1    Kumar, T.M.2
  • 81
    • 0028153112 scopus 로고
    • Bioadhesive polymer buccal patches for buprenorphine controlled delivery: Formulation, in-vitro adhesion and release properties
    • J.H. Guo Bioadhesive polymer buccal patches for buprenorphine controlled delivery: formulation, in-vitro adhesion and release properties Drug Development and Industrial Pharmacy 20 1994 2809 2821
    • (1994) Drug Development and Industrial Pharmacy , vol.20 , pp. 2809-2821
    • Guo, J.H.1
  • 83
    • 0025383213 scopus 로고
    • Ellipsometry studies of the adsorption of cellulose ethers
    • M. Malmsten, and B. Lindman Ellipsometry studies of the adsorption of cellulose ethers Langmuir 6 1990 357 364
    • (1990) Langmuir , vol.6 , pp. 357-364
    • Malmsten, M.1    Lindman, B.2
  • 85
    • 0023529793 scopus 로고
    • Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels
    • H. Park, and J.R. Robinson Mechanisms of mucoadhesion of poly(acrylic acid) hydrogels Pharmaceutical Research 4 1987 457 464
    • (1987) Pharmaceutical Research , vol.4 , pp. 457-464
    • Park, H.1    Robinson, J.R.2
  • 86
    • 0024352077 scopus 로고
    • A novel in situ method to test polymers and coated microparticles for bioadhesion
    • K.V. Ranga Rao, and P. Buri A novel in situ method to test polymers and coated microparticles for bioadhesion International Journal of Pharmaceutics 52 1989 265 270
    • (1989) International Journal of Pharmaceutics , vol.52 , pp. 265-270
    • Ranga Rao, K.V.1    Buri, P.2


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