Bioadhesion: New possibilities for drug administration?

Clinical Pharmacokinetics

Volumn 40, Issue 2, 2001, Pages 77-84

  Woodley, J ^a  

^a NONE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ADHESIVE AGENT; ADVANTAGE S; CARBOMER; CHITOSAN DERIVATIVE; INVASIN; MUCIN; NANOPARTICLE; PLANT LECTIN; POLYCARBOPHIL; POLYMER; ULEX EUROPAEUS AGGLUTININ; UNCLASSIFIED DRUG; WHEAT GERM AGGLUTININ;

DRUG ABSORPTION; DRUG ADMINISTRATION ROUTE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; HUMAN; MACROMOLECULE; MUCOSA CELL; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW;

EID: 0035068551     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-200140020-00001     Document Type: Review

References (52)

1. Binding of acrylic polymers to mucin/epithelial surfaces: Structure-property relationships
2. Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues
3. Polymers with thiol groups: A new generation of mucoadhesive polymers?
4. Design and in vivo evaluation of an oral delivery system for insulin
5. Bioadhesive-based dosage forms: The next generation
6. Formulation and characterisation of a buccoadhesive tablet for the treatment of oral lesions
7. Bioavailability of morphine after administration of a new bioadhesive buccal tablet
8. Design, development, and biopharmaceutical properties of buccoadhesive compacts of pentazocine
9. Potential therapeutic levels of glucagon-like peptide I achieved in humans by a buccal tablet
10. Transmucosal delivery of oxytocin to rabbits using a mucoadhesive buccal patch
11. 3M buccal drug delivery system
12. Progesterone bioadhesive vaginal gel: Scientific description
13. Butoconazole nitrate 2% for vulvovaginal candidiasis. New, single-dose vaginal cream formulation vs. seven day treatment with miconazole nitrate
14. Nasal absorption enhancement: Relevance to nasal drug delivery
15. Intranasal insulin delivery and therapy
16. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
17. Chitosans as absorption enhancers for poorly absorbable drugs 2: Mechanism of absorption enhancement
18. Evaluation of the clearance characteristics of bioadhesive systems in humans
19. Enhancement of nasal absorption of insulin using chitosan nanoparticles
20. Chitosan and its use as a pharmaceutical excipient
21. In vitro evaluation of microparticles and polymer gels for use as nasal platforms for protein delivery
22. Improved nasal bioavailability of FITC-dextran (Mw 4300) from mucoadhesive microspheres in rabbits
23. Evaluation of starch-maltodextrin-Carbopol 974 P mixtures for the nasal delivery of insulin in rabbits
24. Nasal toxicological investigations of Carbopol 971P formulation of apomorphine: Effects on ciliary beat frequency of human nasal primary cell culture and in vivo on rabbit nasal mucosa
25. Oral and nasal immunization with microencapsulated clinically relevant proteins
26. Recent strategies for vaccine formulation in biodegradable polymer particles
27. Ophthalmic drug delivery systems
28. Ocular availability of gentamycin in small animals after topical administration of a conventional eye drop solution and novel long acting bioadhesive ophthalmic drug insert
29. Evaluation of pilocarpine-loaded albumin particles as controlled drug delivery systems for the eye. II: Co-administration with bioadhesive and viscous polymers
30. Bioadhesive microspheres for ophthalmic administration of acyclovir
31. Bioadhesive polymers as platforms for the oral controlled drug delivery III: Oral delivery of chlorothiazide using a bioadhesive polymer
32. Use of a bioadhesive polymer to improve the bioavailability of griseofulvin
33. 14C-labelled poly(acrylic acids): An in-vivo study
34. Transit of pharmaceutical dosage forms through the small intestine
35. N-trimethylated chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo in rats
36. Mucoadhesive polymers in peroral peptide drug delivery: VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo
37. The potential of lectins for delaying the intestinal transit of drugs
38. The potential use of tomato lectin for oral drug delivery: 1. Lectin binding to rat small intestine
39. The potential use of tomato lectin for oral drug delivery: 3. Bioadhesion in vivo
40. Bioadhesion by means of specific binding of tomato lectin
41. In vitro study of lectin-latex conjugates for specific bioadhesion
42. The potential of bioadhesive lectins for the delivery of peptide and protein drugs to the gastrointestinal tract
43. Développment de sytèmes bioadhésifs par conjugaison de microsphères de poly (D,L-lactide) à la lectin de Lycopersicon esculentum L. ou de Lotus tetragonotobus
44. Bioadhesion to the intestine by means of E. coli K99-fimbriae: Gastrointestinal stability and specificity of adherence
45. Utilizing bacterial mechanisms of epithelial cell entry: Invasin-induced oral uptake of latex nanoparticles
46. Enhanced oral uptake of tomato lectin-conjugated nanoparticles in the rat
47. Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo
48. Lectin-mediated bioadhesion: Preparation, stability and caco-2 binding of wheat germ agglutinin-functionalized poly(D,L-lactic-co-glycolic acid)-microspheres
49. Lectin-HPMA copolymer conjugates - Drug carriers for gastrointestinal tract targeting
50. Mucoadhesive DL-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of elcatonin
51. Mucosal immunogenicity of plant lectins in mice