Comparison of the mucoadhesive properties of various polymers

Advanced Drug Delivery Reviews

Volumn 57, Issue 11, 2005, Pages 1713-1723

  Grabovac, Vjera ^a   Guggi, Davide ^b   Bernkop Schnürch, Andreas ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adhesion studies; Influence of drying method; Influence of pH; Mucoadhesive polymers

Indexed keywords

ADHESION; ADHESIVES; DERIVATIVES; DRYING; ORGANIC SOLVENTS; PH EFFECTS; POLYACRYLATES; POLYSACCHARIDES; PRECIPITATION (CHEMICAL); SOLUTIONS;

ADHESION STUDIES; INFLUENCE OF DRYING METHOD; INFLUENCE OF PH; MUCOADHESIVE POLYMERS;

POLYMERS;

ALGINIC ACID; CARBOMER; CARBOPOL 971P; CARBOPOL 974P; CARBOPOL 980; CARBOXYMETHYLCELLULOSE; CARRAGEENAN; CHITOSAN DERIVATIVE; CYSTEINE DERIVATIVE; HYALURONIC ACID; HYDROXYETHYLCELLULOSE; HYDROXYPROPYLCELLULOSE; MACROGOL 6000; MUCOADHESIVE POLYMER; POLYACRYLIC ACID; POLYCARBOPHIL; POLYMER; POLYMETHACRYLIC ACID; POVIDONE; UNCLASSIFIED DRUG;

ADHESION; ANIMAL TISSUE; AQUEOUS SOLUTION; COMPARATIVE STUDY; CONTROLLED STUDY; DATA ANALYSIS; DESICCATION; EVALUATION; FREEZE DRYING; INTESTINE MUCOSA; MUCOADHESION; NONHUMAN; PH; PRECIPITATION; PRIORITY JOURNAL; REVIEW; TENSILE STRENGTH; TIME;

ADHESIVENESS; ANIMALS; CHITOSAN; DESICCATION; FREEZE DRYING; INTESTINAL MUCOSA; MUCOUS MEMBRANE; POLYMERS; POLYSACCHARIDES; SULFHYDRYL COMPOUNDS; SWINE; TENSILE STRENGTH; TISSUE ADHESIVES;

EID: 26644434123     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2005.07.006     Document Type: Review

References (25)

1. N.A. Peppas, and J.J. Sahlin Hydrogels as mucoadhesive and bioadhesive materials: a review Biomaterials 17 1996 1553 1561
2. C. Caramella, M.C. Bonferoni, S. Rossi, and F. Ferrari Rheological and tensile tests for the assessment of polymer-mucin interactions Eur. J. Pharm. Biopharm. 40 1994 213 217
3. J.D. Smart, I.W. Kellaway, and H.E.C. Worthington An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery J. Pharm. Pharmacol. 36 1984 295 299
4. C.-M. Lehr, J.A. Bouwstra, E.H. Schacht, and H.E. Junginger In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers Int. J. Pharm. 78 1992 43 48
5. H.S. Ch'ng, H. Park, P. Kelly, and J.R. Robinson Bioadhesive polymers as platforms for oral controlled drug delivery: II. Synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers J. Pharm. Sci. 74 1985 399 405
6. J.D. Smart The role of water movement and polymer hydration in mucoadhesion Drugs Pharm. Sci. 1999 Marcel Dekker 11 23
7. 1 Int. J. Pharm. 73 21-7-1991 239 243
8. C. Ferrero, and M.R. Jiménez-Castellanos The influence of carbohydrate nature and drying methods on the compaction properties and pore structure of new methyl methacrylate copolymers Int. J. Pharm. 248 6-11-2002 157 171
9. A. Bernkop-Schnürch, and S. Steininger Synthesis and characterisation of mucoadhesive thiolated polymers Int. J. Pharm. 194 2000 239 247
10. M.K. Marschütz, and A. Bernkop-Schnürch Thiolated polymers: self-crosslinking properties of thiolated 450 kDa poly(acrylic acid) and their influence on mucoadhesion Eur. J. Pharm. Sci. 15 2002 387 394
11. M. Roldo, M. Hornof, P. Caliceti, and A. Bernkop-Schnurch Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation Eur. J. Pharm. Biopharm. 57 2004 115 121
12. A. Bernkop-Schnürch, and B. Gilge Anionic mucoadhesive polymers as auxiliary agents for the peroral administration of (poly)peptide drugs: influence of the gastric juice Drug Dev. Ind. Pharm. 26 2000 107 113
13. A. Bernkop-Schnürch S. Dumitriu Mucoadhesive Polymers, Polymeric Biomaterials 2000 Marcel Dekker New York 147 165
14. A. Bernkop-Schnürch Thiomers: a new generation of mucoadhesive polymers Adv. Drug Del. Rev. 57 2005 1569 1582
15. A.B. Bashaiwoldu, F. Podczeck, and J.M. Newton A study on the effect of drying techniques on the mechanical properties of pellets and compacted pellets Eur. J. Pharm. Sci. 21 2004 119 129
16. S. Tamburic, and D.Q.M. Craig A comparison of different in vitro methods for measuring mucoadhesive performance Eur. J. Pharm. Biopharm. 44 1997 159 167
17. M.J. Tobyn, J.R. Johnson, and P.W. Dettmar Factors affecting in vitro gastric mucoadhesion: II. Physical properties of polymers Eur. J. Pharm. Biopharm. 42 1996 56 61
18. W.E. Hennink, and C.F. van Nostrum Novel crosslinking methods to design hydrogels Adv. Drug Deliv. Rev. 54 17-1-2002 13 36
19. A.R. Khare, and N.A. Peppas Characterization of water structure in relation to release behaviour of drugs from pH sensitive hydrogels Proc. Int. Symp. Control. Release Bioact. Mater. 1992 200 201
20. S.A. Mortazavi, and J.D. Smart An investigation into the role of water movement and mucus gel dehydration in mucoadhesion J. Control. Release 25 1993 197 203
21. A. Bernkop-Schnürch, C. Humenberger, and C. Valenta Basic studies on bioadhesive delivery systems for peptide and protein drugs Int. J. Pharm. 165 1998 217 225
22. A.B. Bashaiwoldu, F. Podczeck, and J.M. Newton A study on the effect of drying techniques on the mechanical properties of pellets and compacted pellets Eur. J. Pharm. Sci. 21 2004 119 129
23. A.B. Bashaiwoldu, F. Podczeck, and J.M. Newton A study on the effect of drying techniques on the mechanical properties of pellets and compacted pellets Eur. J. Pharm. Sci. 21 2004 119 129
24. F. Madsen, K. Eberth, and J.D. Smart A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration J. Control. Release 50 1998 167 178
25. M.J. Tobyn, J.R. Johnson, and P.W. Dettmar Factors affecting in vitro gastric mucoadhesion: I. Test conditions and instrumental parameters Eur. J. Pharm. Biopharm. 41 1995 235 241