Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

Molecular Cell

Volumn 62, Issue 4, 2016, Pages 586-602

  Uchikawa, Emiko ^a,b   Lethier, Mathilde ^a,b   Malet, Hélène ^a,b   Brunel, Joanna ^c,d,e,f   Gerlier, Denis ^c,d,e,f   Cusack, Stephen ^a,b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^b UNIV GRENOBLE ALPES   (France)

^c CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^d INSERM   (France)

^e CNRS   (France)

^f UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; PATTERN RECOGNITION RECEPTOR; RNA HELICASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; AVIAN PROTEIN; INTERFERON INDUCED HELICASE C DOMAIN CONTAINING PROTEIN 1; PROTEIN BINDING; RETINOIC ACID INDUCIBLE PROTEIN I; RNA BINDING PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; HUMAN; NONHUMAN; OLIGOMERIZATION; PROTEIN DOMAIN; PROTEIN RNA BINDING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; ANIMAL; BINDING SITE; CELL LINE; CHEMISTRY; CHICKEN; CONFORMATION; GENETIC TRANSFECTION; GENETICS; HYDROLYSIS; METABOLISM; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; AVIAN PROTEINS; BINDING SITES; CELL LINE; CHICKENS; DEAD BOX PROTEIN 58; HUMANS; HYDROLYSIS; INTERFERON-INDUCED HELICASE, IFIH1; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECEPTORS, PATTERN RECOGNITION; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 84969263223     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.04.021     Document Type: Article

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