Chicken MDA5 senses short double-stranded RNA with implications for antiviral response against avian influenza viruses in chicken

Journal of Innate Immunity

Volumn 6, Issue 1, 2014, Pages 58-71

  Hayashi, Tsuyoshi ^a   Watanabe, Chiaki ^a   Suzuki, Yasushi ^a   Tanikawa, Taichiro ^a   Uchida, Yuko ^a,c   Saito, Takehiko ^a,b,c  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c Thailand Japan Zoonotic Diseases Collaborating Center (ZDCC)   (Thailand)

Author keywords

Avian influenza virus; Chicken; Melanomadifferentiation associated gene 5; Retinoic acid inducible gene I; Short double stranded RNA; Type I interferon

Indexed keywords

BETA INTERFERON; CASPASE; CYTOKINE; DOUBLE STRANDED RNA; MDA5 PROTEIN; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; MITOCHONDRIAL PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AVIAN INFLUENZA VIRUS; CHICKEN; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; IMMUNE RESPONSE; INNATE IMMUNITY; INTERFERON INDUCTION; MAMMAL; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VIRUS REPLICATION; ANIMAL TISSUE; ANTIVIRAL THERAPY; DUODENUM; GENE AMPLIFICATION; INFLUENZA A; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; THYMUS; TREATMENT RESPONSE;

ANIMALS; ANTIGENS, VIRAL; AVIAN PROTEINS; CELL LINE; CHICKENS; DEAD-BOX RNA HELICASES; FIBROBLASTS; IMMUNITY; INFLUENZA A VIRUS; INFLUENZA IN BIRDS; INTERFERON-BETA; MITOCHONDRIA; POLY I-C; RNA, DOUBLE-STRANDED; RNA, VIRAL; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84893683041     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000351583     Document Type: Article

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