Polyphyllin VII induces an autophagic cell death by activation of the JNK pathway and inhibition of PI3K/Akt/mTOR pathway in HepG2 cells

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Zhang, Chao ^a   Jia, Xuejing ^a   Wang, Kai ^a   Bao, Jiaolin ^a   Li, Peng ^a   Chen, Meiwan ^a   Wan, Jian Bo ^a   Su, Huanxing ^a   Mei, Zhinan ^b   He, Chengwei ^a  

^a University of Macau   (Macao)

^b SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MTOR PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHYLLIN VII; PROTEIN KINASE B; SAPONIN; TARGET OF RAPAMYCIN KINASE;

ANTAGONISTS AND INHIBITORS; AUTOPHAGY; DRUG EFFECTS; ENZYME ACTIVATION; HEP-G2 CELL LINE; HUMAN; METABOLISM;

AUTOPHAGY; ENZYME ACTIVATION; HEP G2 CELLS; HUMANS; MAP KINASE KINASE 4; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SAPONINS; TOR SERINE-THREONINE KINASES;

EID: 84969165274     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0147405     Document Type: Article

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