Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-Induced Bcl-2 phosphorylation and degradation

Journal of Cellular Biochemistry

Volumn 109, Issue 4, 2010, Pages 764-773

  Zhang, Yu Xi ^a,b   Kong, Chui Ze ^a   Wang, Lin Hui ^b   Li, Jin Yi ^b   Liu, Xian Kui ^a   Xu, Bin ^b   Xu, Chuan Liang ^b   Sun, Ying Hao ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bcl 2; c Jun N terminal kinase; Prostate carcinoma; Ursolic acid

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 8; CASPASE 9; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; URSOLIC ACID;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 9; CELL LINE, TUMOR; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRITERPENES;

EID: 77749311412     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22455     Document Type: Article

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