Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway

Biochemical Pharmacology

Volumn 88, Issue 2, 2014, Pages 150-157

  Li, Yuhua ^a,b   Sun, Yang ^b   Fan, Lei ^b   Zhang, Feng ^b   Meng, Jin ^c   Han, Jin ^b   Guo, Xin ^d   Zhang, Dian ^b   Zhang, Rong ^b   Yue, Zhenggang ^b   Mei, Qibing ^b  

^a No 422 Hospital of PLA   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c 309TH HOSPITAL OF PLA   (China)

^d EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Colorectal cancer (CRC); Paris saponin VII (PSVII); Ras

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ANTINEOPLASTIC AGENT; CASPASE 3; DEXTRAN SULFATE; FLUOROURACIL; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PARIS SAPONIN VII; PROTEIN KINASE B; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER PREVENTION; CARCINOGENESIS; CHEMOPROPHYLAXIS; COLITIS; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GASTROINTESTINAL TOXICITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; TRILLIUM; TRILLIUM TSCHONOSKII; TUMOR CELL LINE; TUMOR VOLUME; TUMOR XENOGRAFT;

APOPTOSIS; COLORECTAL CANCER (CRC); PARIS SAPONIN VII (PSVII); RAS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; COLORECTAL NEOPLASMS; FEMALE; GENES, RAS; GROWTH INHIBITORS; HT29 CELLS; HUMANS; MICE; MICE, INBRED ICR; MICE, NUDE; PLANT EXTRACTS; SAPONINS; SIGNAL TRANSDUCTION; TRILLIUM; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84895560104     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.01.018     Document Type: Article

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