Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling

Leukemia

Volumn 30, Issue 10, 2016, Pages 1993-2001

  Tremblay, C S ^a   Brown, F C ^a   Collett, M ^b   Saw, J ^a   Chiu, S K ^a   Sonderegger, S E ^a   Lucas, S E ^a   Alserihi, R ^c   Chau, N ^b   Toribio, M L ^d   McCormack, M P ^c   Chircop, M ^b   Robinson, P J ^b   Jane, S M ^a,e   Curtis, D J ^a,e  

^a MONASH UNIVERSITY   (Australia)

^b CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^e ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIN II; GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; LIM PROTEIN; LMO2 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL COUNT; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVITY; HETEROZYGOTE; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; LEUKEMOGENESIS; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; T CELL ACUTE LYMPHOBLASTIC LEUKEMIA; THYMOCYTE; ANIMAL; GENETICS; LEUKEMIA, T-CELL; METABOLISM; MUTATION; ONCOGENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; DYNAMIN II; ENDOCYTOSIS; GTP PHOSPHOHYDROLASES; HUMANS; INTERLEUKIN-7; LEUKEMIA, T-CELL; LIM DOMAIN PROTEINS; MICE; MUTATION; ONCOGENES; SIGNAL TRANSDUCTION;

EID: 84966460192     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2016.100     Document Type: Article

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