Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia

Neuroscience Research

Volumn 108, Issue , 2016, Pages 24-33

  Nie, Xingju ^a   Lowe, Danielle W ^a   Rollins, Laura Grace ^b   Bentzley, Jessica ^a   Fraser, Jamie L ^c   Martin, Renee ^d   Singh, Inderjit ^a   Jenkins, Dorothea ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

N acetylcysteine; Neonatal hypoxia ischemia; Neuroprotection; Redox regulation; Sex

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; COLLAGENASE 3; CXCL1 CHEMOKINE; GAMMA INTERFERON; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; NEURONAL NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; AUTACOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION SIZE; CELL DEATH; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG MEGADOSE; ENZYME ACTIVATION; FEMALE; HEMISPHERE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INDUCED HYPOTHERMIA; LONG TERM CARE; MALE; MOTONEURON; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORIMOTOR FUNCTION; SEX DIFFERENCE; TRANSLATIONAL RESEARCH; ANIMAL; BRAIN; BRAIN INFARCTION; DOSE RESPONSE; DRUG EFFECTS; HYPOXIA-ISCHEMIA, BRAIN; METABOLISM; MOTOR PERFORMANCE; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME FACTOR;

ACETYLCYSTEINE; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; BRAIN; BRAIN INFARCTION; CASPASE 3; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFLAMMATION MEDIATORS; MALE; MOTOR SKILLS; NITRIC OXIDE SYNTHASE TYPE II; RATS, SPRAGUE-DAWLEY; SEX FACTORS; TIME FACTORS;

EID: 84966269034     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2016.01.008     Document Type: Article

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