-
1
-
-
84867920077
-
Developing strategies for HIV-1 eradication
-
22867874
-
Durand CM, Blankson JN, Siliciano RF, Developing strategies for HIV-1 eradication. Trends in Immunology. 2012;33(11):554–562. Available from: http://www.sciencedirect.com/science/article/pii/S1471490612001123. doi: 10.1016/j.it.2012.07.00122867874
-
(2012)
Trends in Immunology
, vol.33
, Issue.11
, pp. 554-562
-
-
Durand, C.M.1
Blankson, J.N.2
Siliciano, R.F.3
-
2
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
22837004
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012Jul;487(7408):482–485. Available from: http://www.nature.com/nature/journal/v487/n7408/full/nature11286.html. doi: 10.1038/nature1128622837004
-
(2012)
Nature
, vol.487
, Issue.7408
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
Crooks, A.M.6
-
3
-
-
84911460971
-
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
-
26423811
-
Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, et al. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. The Lancet HIV. 2014;1(1):e13–e21. Available from: http://www.sciencedirect.com/science/article/pii/S2352301814700141. doi: 10.1016/S2352-3018(14)70014-126423811
-
(2014)
The Lancet HIV
, vol.1
, Issue.1
, pp. 13-21
-
-
Rasmussen, T.A.1
Tolstrup, M.2
Brinkmann, C.R.3
Olesen, R.4
Erikstrup, C.5
Solomon, A.6
-
4
-
-
84895740875
-
A Pilot Study Assessing the Safety and Latency-Reversing Activity of Disulfiram in HIV-1 Infected Adults on Antiretroviral Therapy
-
24336828
-
Spivak AM, Andrade A, Eisele E, Hoh R, Bacchetti P, Bumpus NN, et al. A Pilot Study Assessing the Safety and Latency-Reversing Activity of Disulfiram in HIV-1 Infected Adults on Antiretroviral Therapy. Clinical Infectious Diseases. 2014Mar;58(6):883–890. Available from: http://cid.oxfordjournals.org/content/58/6/883. doi: 10.1093/cid/cit81324336828
-
(2014)
Clinical Infectious Diseases
, vol.58
, Issue.6
, pp. 883-890
-
-
Spivak, A.M.1
Andrade, A.2
Eisele, E.3
Hoh, R.4
Bacchetti, P.5
Bumpus, N.N.6
-
5
-
-
84878503062
-
Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient
-
23671416
-
Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, et al. Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient. PLoS Pathog. 2013May;9(5):e1003347. doi: 10.1371/journal.ppat.100334723671416
-
(2013)
PLoS Pathog
, vol.9
, Issue.5
, pp. 1003347
-
-
Yukl, S.A.1
Boritz, E.2
Busch, M.3
Bentsen, C.4
Chun, T.W.5
Douek, D.6
-
6
-
-
84877278315
-
Long-Term Reduction in Peripheral Blood HIV-1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation
-
23460751
-
Henrich TJ, Hu Z, Li JZ, Sciaranghella G, Busch MP, Keating SM, et al. Long-Term Reduction in Peripheral Blood HIV-1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation. Journal of Infectious Diseases. 2013Jun;207(11):1694–1702. Available from: http://jid.oxfordjournals.org/content/early/2013/02/28/infdis.jit086. doi: 10.1093/infdis/jit08623460751
-
(2013)
Journal of Infectious Diseases
, vol.207
, Issue.11
, pp. 1694-1702
-
-
Henrich, T.J.1
Hu, Z.2
Li, J.Z.3
Sciaranghella, G.4
Busch, M.P.5
Keating, S.M.6
-
7
-
-
84906970468
-
Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases
-
25047577
-
Henrich TJ, Hanhauser E, Marty FM, Sirignano MN, Keating S, Lee TH, et al. Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation: Report of 2 Cases. Annals of Internal Medicine. 2014Sep;161(5):319–327. doi: 10.7326/M14-102725047577
-
(2014)
Annals of Internal Medicine
, vol.161
, Issue.5
, pp. 319-327
-
-
Henrich, T.J.1
Hanhauser, E.2
Marty, F.M.3
Sirignano, M.N.4
Keating, S.5
Lee, T.H.6
-
8
-
-
84923064466
-
Viremic relapse after HIV-1 remission in a perinatally infected child
-
25693029
-
Luzuriaga K, Gay H, Ziemniak C, Sanborn KB, Somasundaran M, Rainwater-Lovett K, et al. Viremic relapse after HIV-1 remission in a perinatally infected child. The New England Journal of Medicine. 2015Feb;372(8):786–788. doi: 10.1056/NEJMc141393125693029
-
(2015)
The New England Journal of Medicine
, vol.372
, Issue.8
, pp. 786-788
-
-
Luzuriaga, K.1
Gay, H.2
Ziemniak, C.3
Sanborn, K.B.4
Somasundaran, M.5
Rainwater-Lovett, K.6
-
9
-
-
78549235738
-
Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication
-
20962613
-
Chun TW, Justement JS, Murray D, Hallahan CW, Maenza J, Collier AC, et al. Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication. AIDS. 2010Nov;24(18):2803–2808. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154092/. doi: 10.1097/QAD.0b013e328340a23920962613
-
(2010)
AIDS
, vol.24
, Issue.18
, pp. 2803-2808
-
-
Chun, T.W.1
Justement, J.S.2
Murray, D.3
Hallahan, C.W.4
Maenza, J.5
Collier, A.C.6
-
10
-
-
84907240033
-
Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1
-
25097264
-
Hill AL, Rosenbloom DIS, Fu F, Nowak MA, Siliciano RF, Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1. Proc Natl Acad Sci USA. 2014Sep;111(37):13475–13480. Available from: http://www.pnas.org/content/111/37/13475. doi: 10.1073/pnas.140666311125097264
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.37
, pp. 13475-13480
-
-
Hill, A.L.1
Rosenbloom, D.I.S.2
Fu, F.3
Nowak, M.A.4
Siliciano, R.F.5
-
11
-
-
24944518559
-
Enhanced culture assay for detection and quantitation of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals
-
16061962
-
Siliciano JD, Siliciano RF, Enhanced culture assay for detection and quantitation of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals. Methods in Molecular Biology. 2005;304:3–15. 16061962
-
(2005)
Methods in Molecular Biology
, vol.304
, pp. 3-15
-
-
Siliciano, J.D.1
Siliciano, R.F.2
-
12
-
-
84873472629
-
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
-
23459007
-
Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, et al. Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies. PLoS Pathog. 2013Feb;9(2):e1003174. doi: 10.1371/journal.ppat.100317423459007
-
(2013)
PLoS Pathog
, vol.9
, Issue.2
, pp. 1003174
-
-
Eriksson, S.1
Graf, E.H.2
Dahl, V.3
Strain, M.C.4
Yukl, S.A.5
Lysenko, E.S.6
-
13
-
-
84925842804
-
Towards an HIV-1 cure: measuring the latent reservoir
-
25747663
-
Bruner KM, Hosmane NN, Siliciano RF, Towards an HIV-1 cure: measuring the latent reservoir. Trends in Microbiology. 2015Jan;23(4):192–203. Available from: http://www.cell.com/article/S0966842X1500027X/abstract. doi: 10.1016/j.tim.2015.01.01325747663
-
(2015)
Trends in Microbiology
, vol.23
, Issue.4
, pp. 192-203
-
-
Bruner, K.M.1
Hosmane, N.N.2
Siliciano, R.F.3
-
14
-
-
84964853070
-
-
In preparation
-
Rosenbloom DI, Elliott O, Hill AL, Henrich T, Siliciano J, Siliciano R, Designing and interpreting limiting dilution assays for estimating the size of HIV reservoirs. In preparation. 2015;.
-
(2015)
Designing and interpreting limiting dilution assays for estimating the size of HIV reservoirs
-
-
Rosenbloom, D.I.1
Elliott, O.2
Hill, A.L.3
Henrich, T.4
Siliciano, J.5
Siliciano, R.6
-
15
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
-
12754504
-
Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, Margolick JB, et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med. 2003Jun;9(6):727–728. doi: 10.1038/nm88012754504
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
Quinn, T.C.4
Chadwick, K.5
Margolick, J.B.6
-
16
-
-
84946096080
-
Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies
-
25877550
-
Crooks AM, Bateson R, Cope AB, Dahl NP, Griggs MK, Kuruc JD, et al. Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies. Journal of Infectious Diseases. 2015Apr;p. jiv218. Available from: http://jid.oxfordjournals.org/content/early/2015/04/15/infdis.jiv218. doi: 10.1093/infdis/jiv21825877550
-
(2015)
Journal of Infectious Diseases
-
-
Crooks, A.M.1
Bateson, R.2
Cope, A.B.3
Dahl, N.P.4
Griggs, M.K.5
Kuruc, J.D.6
-
17
-
-
84864015446
-
HIV Model Parameter Estimates from Interruption Trial Data including Drug Efficacy and Reservoir Dynamics
-
22815727
-
Luo R, Piovoso MJ, Martinez-Picado J, Zurakowski R, HIV Model Parameter Estimates from Interruption Trial Data including Drug Efficacy and Reservoir Dynamics. PLoS ONE. 2012Jul;7(7):e40198. doi: 10.1371/journal.pone.004019822815727
-
(2012)
PLoS ONE
, vol.7
, Issue.7
, pp. 40198
-
-
Luo, R.1
Piovoso, M.J.2
Martinez-Picado, J.3
Zurakowski, R.4
-
18
-
-
0034071659
-
Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression
-
Ruiz L, Martinez-Picado J, Romeu J, Paredes R, Zayat MK, Marfil S, et al. Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression. AIDS. 2000;14(4):397.
-
(2000)
AIDS
, vol.14
, Issue.4
, pp. 397
-
-
Ruiz, L.1
Martinez-Picado, J.2
Romeu, J.3
Paredes, R.4
Zayat, M.K.5
Marfil, S.6
-
19
-
-
77951604611
-
Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression
-
20409455
-
Singh A, Razooky B, Cox CD, Simpson ML, Weinberger LS, Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression. Biophysical journal. 2010;98(8):L32–4. doi: 10.1016/j.bpj.2010.03.00120409455
-
(2010)
Biophysical journal
, vol.98
, Issue.8
, pp. 32-34
-
-
Singh, A.1
Razooky, B.2
Cox, C.D.3
Simpson, M.L.4
Weinberger, L.S.5
-
20
-
-
84958078498
-
HIV-1 virion production from single inducible proviruses following T-cell activation ex vivo
-
26559835, .;p. JVI.02520–15
-
Bui JK, Mellors JW, Cillo AR, HIV-1 virion production from single inducible proviruses following T-cell activation ex vivo. Journal of Virology. 2015Nov;p. JVI.02520–15. Available from: http://jvi.asm.org.ezp-prod1.hul.harvard.edu/content/early/2015/11/05/JVI.02520-15. doi: 10.1128/JVI.02520-1526559835
-
(2015)
Journal of Virology
-
-
Bui, J.K.1
Mellors, J.W.2
Cillo, A.R.3
-
21
-
-
84864068244
-
Standing Genetic Variation and the Evolution of Drug Resistance in HIV
-
22685388
-
Pennings PS, Standing Genetic Variation and the Evolution of Drug Resistance in HIV. PLoS Comput Biol. 2012Jun;8(6):e1002527. doi: 10.1371/journal.pcbi.100252722685388
-
(2012)
PLoS Comput Biol
, vol.8
, Issue.6
, pp. 1002527
-
-
Pennings, P.S.1
-
22
-
-
84896691480
-
Loss and recovery of genetic diversity in adapting populations of HIV
-
24465214
-
Pennings PS, Kryazhimskiy S, Wakeley J, Loss and recovery of genetic diversity in adapting populations of HIV. PLoS Genetics. 2014;10(1):e1004000. doi: 10.1371/journal.pgen.100400024465214
-
(2014)
PLoS Genetics
, vol.10
, Issue.1
, pp. 1004000
-
-
Pennings, P.S.1
Kryazhimskiy, S.2
Wakeley, J.3
-
23
-
-
0032824180
-
Linkage disequilibrium test implies a large effective population number for HIV in vivo
-
10485899
-
Rouzine IM, Coffin JM, Linkage disequilibrium test implies a large effective population number for HIV in vivo. Proc Natl Acad Sci USA. 1999;96(19):10758–10763. doi: 10.1073/pnas.96.19.1075810485899
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.19
, pp. 10758-10763
-
-
Rouzine, I.M.1
Coffin, J.M.2
-
24
-
-
84907228543
-
Stochastic variability in HIV affects viral eradication
-
Rouzine IM, Razooky BS, Weinberger LS, Stochastic variability in HIV affects viral eradication. Proceedings of the National Academy of Sciences. 2014Sep;111(37):13251–13252. Available from: http://www.pnas.org/content/111/37/13251. doi: 10.1073/pnas.1413362111
-
(2014)
Proceedings of the National Academy of Sciences
, vol.111
, Issue.37
, pp. 13251-13252
-
-
Rouzine, I.M.1
Razooky, B.S.2
Weinberger, L.S.3
-
25
-
-
84887028999
-
Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant
-
24152233
-
Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M, Chun TW, et al. Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant. New England Journal of Medicine. 2013;369(19):1828–1835. Available from: http://www.nejm.org/doi/full/10.1056/NEJMoa1302976. doi: 10.1056/NEJMoa130297624152233
-
(2013)
New England Journal of Medicine
, vol.369
, Issue.19
, pp. 1828-1835
-
-
Persaud, D.1
Gay, H.2
Ziemniak, C.3
Chen, Y.H.4
Piatak, M.5
Chun, T.W.6
-
26
-
-
84862189831
-
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection
-
22645358
-
Archin NM, Vaidya NK, Kuruc JD, Liberty AL, Wiegand A, Kearney MF, et al. Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection. Proc Natl Acad Sci USA. 2012Jun;109(24):9523–9528. doi: 10.1073/pnas.112024810922645358
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.24
, pp. 9523-9528
-
-
Archin, N.M.1
Vaidya, N.K.2
Kuruc, J.D.3
Liberty, A.L.4
Wiegand, A.5
Kearney, M.F.6
-
27
-
-
60549090253
-
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation
-
19213682
-
Hütter G, Nowak D, Mossner M, Ganepola S, Möig A, Allers K, et al. Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation. New England Journal of Medicine. 2009;360(7):692–698. Available from: http://www.nejm.org/doi/full/10.1056/NEJMoa0802905. doi: 10.1056/NEJMoa080290519213682
-
(2009)
New England Journal of Medicine
, vol.360
, Issue.7
, pp. 692-698
-
-
Hütter, G.1
Nowak, D.2
Mossner, M.3
Ganepola, S.4
Möig, A.5
Allers, K.6
-
28
-
-
84964907500
-
-
Henrich TJ, Hanhauser E, Sirignano M, Davis B, Lee TH, Keating S, et al. In depth investigation of peripheral and gut HIV-1 reservoirs, HIV-specific cellular immunity, and host microchimerism following allogeneic hematopoietic stem cell transplantation. In: International AIDS Society. vol. WELB-05. Kuala Lumpur, Malasia: International AIDS Society; 2013. Available from: http://pag.ias2013.org/Abstracts.aspx?AID=3165.
-
(2013)
International AIDS Society
, vol.vol. WELB-05
-
-
Henrich, T.J.1
Hanhauser, E.2
Sirignano, M.3
Davis, B.4
Lee, T.H.5
Keating, S.6
-
29
-
-
84964878406
-
-
Henrich TJ, Challenges and strategies towards a functional cure: how low do you need to go? In: HIV Persistence during Therapy. Miami, Florida: Informed Horizons, LLC; 2013. Available from: http://pag.ias2013.org/Abstracts.aspx?AID=3165.
-
(2013)
HIV Persistence during Therapy
-
-
Henrich, T.J.1
-
30
-
-
84891586787
-
Hematopoietic cell transplantation and HIV cure: where we are and what next?
-
24009230
-
Zou S, Glynn S, Kuritzkes D, Shah M, Cook N, Berliner N, et al. Hematopoietic cell transplantation and HIV cure: where we are and what next?Blood. 2013Oct;122(18):3111–3115. Available from: http://bloodjournal.hematologylibrary.org/content/122/18/3111. doi: 10.1182/blood-2013-07-51831624009230
-
(2013)
Blood
, vol.122
, Issue.18
, pp. 3111-3115
-
-
Zou, S.1
Glynn, S.2
Kuritzkes, D.3
Shah, M.4
Cook, N.5
Berliner, N.6
-
31
-
-
84880191734
-
Plasma viremia and cellular HIV-1 DNA persist despite autologous hematopoietic stem cell transplantation for HIV-related lymphoma
-
23493152
-
Cillo AR, Krishnan A, Mitsuyasu RT, McMahon DK, Li S, Rossi JJ, et al. Plasma viremia and cellular HIV-1 DNA persist despite autologous hematopoietic stem cell transplantation for HIV-related lymphoma. Journal of Acquired Immune Deficiency Syndromes. 2013Aug;63(4):438–441. doi: 10.1097/QAI.0b013e31828e616323493152
-
(2013)
Journal of Acquired Immune Deficiency Syndromes
, vol.63
, Issue.4
, pp. 438-441
-
-
Cillo, A.R.1
Krishnan, A.2
Mitsuyasu, R.T.3
McMahon, D.K.4
Li, S.5
Rossi, J.J.6
-
32
-
-
84886769508
-
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
-
24243014
-
Ho YC, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DIS, et al. Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure. Cell. 2013Oct;155(3):540–551. doi: 10.1016/j.cell.2013.09.02024243014
-
(2013)
Cell
, vol.155
, Issue.3
, pp. 540-551
-
-
Ho, Y.C.1
Shan, L.2
Hosmane, N.N.3
Wang, J.4
Laskey, S.B.5
Rosenbloom, D.I.S.6
-
33
-
-
46049096485
-
Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs
-
Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, et al. Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nature medicine. 2008;14(7):762766. doi: 10.1038/nm1777
-
(2008)
Nature medicine
, vol.14
, Issue.7
, pp. 762766
-
-
Shen, L.1
Peterson, S.2
Sedaghat, A.R.3
McMahon, M.A.4
Callender, M.5
Zhang, H.6
-
34
-
-
84857955750
-
A quantitative basis for antiretroviral therapy for HIV-1 infection
-
22344296
-
Jilek BL, Zarr M, Sampah ME, Rabi SA, Bullen CK, Lai J, et al. A quantitative basis for antiretroviral therapy for HIV-1 infection. Nature Medicine. 2012Feb;18(3):446–451. Available from: http://www.nature.com/nm/journal/v18/n3/full/nm.2649.html. doi: 10.1038/nm.264922344296
-
(2012)
Nature Medicine
, vol.18
, Issue.3
, pp. 446-451
-
-
Jilek, B.L.1
Zarr, M.2
Sampah, M.E.3
Rabi, S.A.4
Bullen, C.K.5
Lai, J.6
-
35
-
-
2142829435
-
Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads
-
15073683
-
Kieffer TL, Finucane MM, Nettles RE, Quinn TC, Broman KW, Ray SC, et al. Genotypic analysis of HIV-1 drug resistance at the limit of detection: virus production without evolution in treated adults with undetectable HIV loads. J Infect Dis. 2004Apr;189(8):1452–1465. doi: 10.1086/38248815073683
-
(2004)
J Infect Dis
, vol.189
, Issue.8
, pp. 1452-1465
-
-
Kieffer, T.L.1
Finucane, M.M.2
Nettles, R.E.3
Quinn, T.C.4
Broman, K.W.5
Ray, S.C.6
-
36
-
-
55949083820
-
HIV rebounds from latently infected cells, rather than from continuing low-level replication
-
18936487
-
Joos B, Fischer M, Kuster H, Pillai SK, Wong JK, Böni J, et al. HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc Natl Acad Sci USA. 2008Oct;105(43):16725–16730. doi: 10.1073/pnas.080419210518936487
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.43
, pp. 16725-16730
-
-
Joos, B.1
Fischer, M.2
Kuster, H.3
Pillai, S.K.4
Wong, J.K.5
Böni, J.6
-
37
-
-
77956856393
-
The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial
-
20711481
-
Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, et al. The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial. PLoS Med. 2010Aug;7(8):e1000321. doi: 10.1371/journal.pmed.100032120711481
-
(2010)
PLoS Med
, vol.7
, Issue.8
, pp. 1000321
-
-
Gandhi, R.T.1
Zheng, L.2
Bosch, R.J.3
Chan, E.S.4
Margolis, D.M.5
Read, S.6
-
38
-
-
67249121143
-
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
-
19470482
-
Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, et al. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci USA. 2009;106(23):9403. doi: 10.1073/pnas.090310710619470482
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.23
, pp. 9403
-
-
Dinoso, J.B.1
Kim, S.Y.2
Wiegand, A.M.3
Palmer, S.E.4
Gange, S.J.5
Cranmer, L.6
-
39
-
-
84868664375
-
Antiretroviral dynamics determines HIV evolution and predicts therapy outcome
-
22941277
-
Rosenbloom DIS, Hill AL, Rabi SA, Siliciano RF, Nowak MA, Antiretroviral dynamics determines HIV evolution and predicts therapy outcome. Nature Medicine. 2012;18(9):1378–1385. Available from: http://www.nature.com.ezp-prod1.hul.harvard.edu/nm/journal/v18/n9/full/nm.2892.html. doi: 10.1038/nm.289222941277
-
(2012)
Nature Medicine
, vol.18
, Issue.9
, pp. 1378-1385
-
-
Rosenbloom, D.I.S.1
Hill, A.L.2
Rabi, S.A.3
Siliciano, R.F.4
Nowak, M.A.5
-
40
-
-
84878666650
-
Modelling HIV-1 2-LTR dynamics following raltegravir intensification
-
Luo R, Cardozo EF, Piovoso MJ, Wu H, Buzon MJ, Martinez-Picado J, et al. Modelling HIV-1 2-LTR dynamics following raltegravir intensification. Journal of The Royal Society Interface. 2013Jul;10(84). Available from: http://rsif.royalsocietypublishing.org/content/10/84/20130186. doi: 10.1098/rsif.2013.0186
-
(2013)
Journal of The Royal Society Interface
, vol.10
, Issue.84
-
-
Luo, R.1
Cardozo, E.F.2
Piovoso, M.J.3
Wu, H.4
Buzon, M.J.5
Martinez-Picado, J.6
-
41
-
-
34548424552
-
Limits on Replenishment of the Resting CD4+ T Cell Reservoir for HIV in Patients on HAART
-
17784786
-
Sedaghat AR, Siliciano JD, Brennan TP, Wilke CO, Siliciano RF, Limits on Replenishment of the Resting CD4+ T Cell Reservoir for HIV in Patients on HAART. PLoS Pathog. 2007;3(8):e122. Available from: http://dx.plos.org/10.1371/journal.ppat.0030122. doi: 10.1371/journal.ppat.003012217784786
-
(2007)
PLoS Pathog
, vol.3
, Issue.8
, pp. 122
-
-
Sedaghat, A.R.1
Siliciano, J.D.2
Brennan, T.P.3
Wilke, C.O.4
Siliciano, R.F.5
-
42
-
-
0033592967
-
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
-
Davey RT, JrBhat N, Yoder C, Chun TW, Metcalf JA, Dewar R, et al. HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression. Proc Natl Acad Sci USA. 1999;96(26):1510915114.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.26
, pp. 1510915114
-
-
Davey, R.T.1
Bhat, N.2
Yoder, C.3
Chun, T.W.4
Metcalf, J.A.5
Dewar, R.6
-
43
-
-
77952686145
-
Estimation of the Initial Viral Growth Rate and Basic Reproductive Number during Acute HIV-1 Infection
-
20357090
-
Ribeiro RM, Qin L, Chavez LL, Li D, Self SG, Perelson AS, Estimation of the Initial Viral Growth Rate and Basic Reproductive Number during Acute HIV-1 Infection. Journal of Virology. 2010Jun;84(12):6096–6102. Available from: http://jvi.asm.org/content/84/12/6096.abstract. doi: 10.1128/JVI.00127-1020357090
-
(2010)
Journal of Virology
, vol.84
, Issue.12
, pp. 6096-6102
-
-
Ribeiro, R.M.1
Qin, L.2
Chavez, L.L.3
Li, D.4
Self, S.G.5
Perelson, A.S.6
-
44
-
-
44649102135
-
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
-
18490657, PMC2387184
-
Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proceedings of the National Academy of Sciences of the United States of America. 2008May;105(21):7552–7557. PMC2387184. Available from: http://www.pubmedcentral.nih.gov.ezp-prod1.hul.harvard.edu/articlerender.fcgi?artid=2387184. doi: 10.1073/pnas.080220310518490657
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.21
, pp. 7552-7557
-
-
Keele, B.F.1
Giorgi, E.E.2
Salazar-Gonzalez, J.F.3
Decker, J.M.4
Pham, K.T.5
Salazar, M.G.6
-
45
-
-
33745245733
-
Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells
-
16775332
-
Bailey JR, Sedaghat AR, Kieffer T, Brennan T, Lee PK, Wind-Rotolo M, et al. Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells. J Virol. 2006;80(13):6441. doi: 10.1128/JVI.00591-0616775332
-
(2006)
J Virol
, vol.80
, Issue.13
, pp. 6441
-
-
Bailey, J.R.1
Sedaghat, A.R.2
Kieffer, T.3
Brennan, T.4
Lee, P.K.5
Wind-Rotolo, M.6
-
46
-
-
84873044224
-
An Increasing Proportion of Monotypic HIV-1 DNA Sequences during Antiretroviral Treatment Suggests Proliferation of HIV-Infected Cells
-
23175380
-
Wagner TA, McKernan JL, Tobin NH, Tapia KA, Mullins JI, Frenkel LM, An Increasing Proportion of Monotypic HIV-1 DNA Sequences during Antiretroviral Treatment Suggests Proliferation of HIV-Infected Cells. Journal of Virology. 2013Feb;87(3):1770–1778. Available from: http://jvi.asm.org/content/87/3/1770. doi: 10.1128/JVI.01985-1223175380
-
(2013)
Journal of Virology
, vol.87
, Issue.3
, pp. 1770-1778
-
-
Wagner, T.A.1
McKernan, J.L.2
Tobin, N.H.3
Tapia, K.A.4
Mullins, J.I.5
Frenkel, L.M.6
-
47
-
-
84897437605
-
Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy
-
24651464
-
Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O’Shea A, et al. Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy. PLoS Pathog. 2014Mar;10(3):e1004010. doi: 10.1371/journal.ppat.100401024651464
-
(2014)
PLoS Pathog
, vol.10
, Issue.3
, pp. 1004010
-
-
Kearney, M.F.1
Spindler, J.2
Shao, W.3
Yu, S.4
Anderson, E.M.5
O’Shea, A.6
-
48
-
-
84904115855
-
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
-
24968937
-
Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science. 2014Jul;345(6193):179–183. Available from: http://www.sciencemag.org/content/345/6193/179. doi: 10.1126/science.125419424968937
-
(2014)
Science
, vol.345
, Issue.6193
, pp. 179-183
-
-
Maldarelli, F.1
Wu, X.2
Su, L.3
Simonetti, F.R.4
Shao, W.5
Hill, S.6
-
49
-
-
84922249841
-
HIV-1 Integration Landscape during Latent and Active Infection
-
25635456
-
Cohn LB, Silva IT, Oliveira TY, Rosales RA, Parrish EH, Learn GH, et al. HIV-1 Integration Landscape during Latent and Active Infection. Cell. 2015Jan;160(3):420–432. doi: 10.1016/j.cell.2015.01.02025635456
-
(2015)
Cell
, vol.160
, Issue.3
, pp. 420-432
-
-
Cohn, L.B.1
Silva, I.T.2
Oliveira, T.Y.3
Rosales, R.A.4
Parrish, E.H.5
Learn, G.H.6
-
50
-
-
84924365877
-
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption
-
25713386
-
Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, et al. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proc Natl Acad Sci USA. 2015Mar;112(10):E1126–E1134. Available from: http://www.pnas.org/content/112/10/E1126. doi: 10.1073/pnas.141492611225713386
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.10
, pp. 1126-1134
-
-
Rothenberger, M.K.1
Keele, B.F.2
Wietgrefe, S.W.3
Fletcher, C.V.4
Beilman, G.J.5
Chipman, J.G.6
-
51
-
-
84938774688
-
HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5–8 Days Implications for HIV Remission
-
26133551
-
Pinkevych M, Cromer D, Tolstrup M, Grimm AJ, Cooper DA, Lewin SR, et al. HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5–8 Days Implications for HIV Remission. PLoS Pathog. 2015Jul;11(7):e1005000. doi: 10.1371/journal.ppat.100500026133551
-
(2015)
PLoS Pathog
, vol.11
, Issue.7
, pp. 1005000
-
-
Pinkevych, M.1
Cromer, D.2
Tolstrup, M.3
Grimm, A.J.4
Cooper, D.A.5
Lewin, S.R.6
-
52
-
-
84984843571
-
Insufficient evidence for rare activation of latent HIV in the absence of reservoir-reducing interventions
-
In press (Formal Comment)
-
Hill AL, Rosenbloom DIS, Siliciano JD, Siliciano RF, Insufficient evidence for rare activation of latent HIV in the absence of reservoir-reducing interventions. PLoS Pathogens. 2016;In press (Formal Comment).
-
(2016)
PLoS Pathogens
-
-
Hill, A.L.1
Rosenbloom, D.I.S.2
Siliciano, J.D.3
Siliciano, R.F.4
-
53
-
-
22744441386
-
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
-
16051143
-
Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV, Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell. 2005;122(2):169–182. doi: 10.1016/j.cell.2005.06.00616051143
-
(2005)
Cell
, vol.122
, Issue.2
, pp. 169-182
-
-
Weinberger, L.S.1
Burnett, J.C.2
Toettcher, J.E.3
Arkin, A.P.4
Schaffer, D.V.5
-
54
-
-
68349139711
-
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
-
19543283
-
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med. 2009;15(8):893–900. doi: 10.1038/nm.197219543283
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 893-900
-
-
Chomont, N.1
El-Far, M.2
Ancuta, P.3
Trautmann, L.4
Procopio, F.A.5
Yassine-Diab, B.6
-
55
-
-
84905917318
-
Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
-
25011556
-
Wagner TA, McLaughlin S, Garg K, Cheung CY, Larsen BB, Styrchak S, et al. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science. 2014;345(6196):570–573. Available from: http://science.sciencemag.org/content/345/6196/570.short. doi: 10.1126/science.125630425011556
-
(2014)
Science
, vol.345
, Issue.6196
, pp. 570-573
-
-
Wagner, T.A.1
McLaughlin, S.2
Garg, K.3
Cheung, C.Y.4
Larsen, B.B.5
Styrchak, S.6
-
56
-
-
84957558724
-
Persistent HIV-1 replication maintains the tissue reservoir during therapy
-
26814962
-
Lorenzo-Redondo R, Fryer HR, Bedford T, Kim EY, Archer J, Kosakovsky Pond SL, et al. Persistent HIV-1 replication maintains the tissue reservoir during therapy. Nature. 2016Feb;530(7588):51–56. Available from: http://www.nature.com/nature/journal/v530/n7588/full/nature16933.html. doi: 10.1038/nature1693326814962
-
(2016)
Nature
, vol.530
, Issue.7588
, pp. 51-56
-
-
Lorenzo-Redondo, R.1
Fryer, H.R.2
Bedford, T.3
Kim, E.Y.4
Archer, J.5
Kosakovsky Pond, S.L.6
-
57
-
-
0033681160
-
Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection
-
11069234
-
Blankson JN, Finzi D, Pierson TC, Sabundayo BP, Chadwick K, Margolick JB, et al. Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection. Journal of Infectious Diseases. 2000;182(6):1636–1642. Available from: http://jid.oxfordjournals.org/content/182/6/1636.short. doi: 10.1086/31761511069234
-
(2000)
Journal of Infectious Diseases
, vol.182
, Issue.6
, pp. 1636-1642
-
-
Blankson, J.N.1
Finzi, D.2
Pierson, T.C.3
Sabundayo, B.P.4
Chadwick, K.5
Margolick, J.B.6
-
58
-
-
84875985311
-
Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study
-
23516360
-
Sáez-Cirión A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, et al. Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study. PLoS pathogens. 2013Mar;9(3):e1003211. doi: 10.1371/journal.ppat.100321123516360
-
(2013)
PLoS pathogens
, vol.9
, Issue.3
, pp. 1003211
-
-
Sáez-Cirión, A.1
Bacchus, C.2
Hocqueloux, L.3
Avettand-Fenoel, V.4
Girault, I.5
Lecuroux, C.6
-
59
-
-
84928718905
-
Post-treatment control of HIV infection
-
Conway JM, Perelson AS, Post-treatment control of HIV infection. Proceedings of the National Academy of Sciences. 2015Apr;112(17):5467–5472. Available from: http://www.pnas.org/content/112/17/5467. doi: 10.1073/pnas.1419162112
-
(2015)
Proceedings of the National Academy of Sciences
, vol.112
, Issue.17
, pp. 5467-5472
-
-
Conway, J.M.1
Perelson, A.S.2
|