메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

HIV model parameter estimates from interruption trial data including drug efficacy and reservoir dynamics

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT;

EID: 84864015446     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040198     Document Type: Article
Times cited : (64)

References (47)
  • 1
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, et al. (1995) Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373: 117-122.
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3    Johnson, V.A.4    Emini, E.A.5
  • 2
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, et al. (1995) Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373: 123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, A.U.2    Perelson, A.S.3    Chen, W.4    Leonard, J.M.5
  • 3
    • 0028804588 scopus 로고
    • Modeling defective interfering virus therapy for AIDS: conditions for HIV survival
    • Nelson GW, Perelson AS, (1995) Modeling defective interfering virus therapy for AIDS: conditions for HIV survival. Math Biosci 125: 127-153.
    • (1995) Math Biosci , vol.125 , pp. 127-153
    • Nelson, G.W.1    Perelson, A.S.2
  • 4
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD, (1996) HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271: 1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 5
    • 33750690698 scopus 로고    scopus 로고
    • Model selection and mixed-effects modeling of HIV infection dynamics
    • Bortz DM, Nelson PW, (2006) Model selection and mixed-effects modeling of HIV infection dynamics. Bull Math Biol 68: 2005-2025.
    • (2006) Bull Math Biol , vol.68 , pp. 2005-2025
    • Bortz, D.M.1    Nelson, P.W.2
  • 6
    • 0035875860 scopus 로고    scopus 로고
    • HIV dynamics and t-cell immunity after three structured treatment interruptions in chronic HIV-1 infection
    • Ruiz L, Carcelain G, Martnez-Picado J, Frost S, Marfil S, et al. (2001) HIV dynamics and t-cell immunity after three structured treatment interruptions in chronic HIV-1 infection. AIDS 15: F19-F27.
    • (2001) AIDS , vol.15
    • Ruiz, L.1    Carcelain, G.2    Martnez-Picado, J.3    Frost, S.4    Marfil, S.5
  • 7
    • 0034615789 scopus 로고    scopus 로고
    • Modeling plasma virus concentration during primary HIV infection
    • Stafford MA, Corey L, Cao Y, Daar ES, Ho DD, et al. (2000) Modeling plasma virus concentration during primary HIV infection. J Theor Biol 203: 285-301.
    • (2000) J Theor Biol , vol.203 , pp. 285-301
    • Stafford, M.A.1    Corey, L.2    Cao, Y.3    Daar, E.S.4    Ho, D.D.5
  • 8
    • 0037292271 scopus 로고    scopus 로고
    • Identifiability of nonlinear systems with application to HIV/AIDS models
    • Xia X, Moog CH, (2003) Identifiability of nonlinear systems with application to HIV/AIDS models. IEEE T Automat Contr 48: 330-336.
    • (2003) IEEE T Automat Contr , vol.48 , pp. 330-336
    • Xia, X.1    Moog, C.H.2
  • 9
    • 41049103588 scopus 로고    scopus 로고
    • Parameter identifiability and estimation of HIV/AIDS dynamic models
    • Wu H, Zhu H, Miao H, Perelson AS, (2008) Parameter identifiability and estimation of HIV/AIDS dynamic models. Bull Math Biol 70: 785-799.
    • (2008) Bull Math Biol , vol.70 , pp. 785-799
    • Wu, H.1    Zhu, H.2    Miao, H.3    Perelson, A.S.4
  • 10
    • 62749173565 scopus 로고    scopus 로고
    • Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inference
    • Miao H, Dykes C, Demeter LM, Wu H, (2009) Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inference. Biometrics 65: 292-300.
    • (2009) Biometrics , vol.65 , pp. 292-300
    • Miao, H.1    Dykes, C.2    Demeter, L.M.3    Wu, H.4
  • 11
    • 84870259530 scopus 로고    scopus 로고
    • Estimation of constant and time-varying dynamic parameters of HIV infection in a nonlinear differential equation model
    • Liang H, Miao H, Wu H, (2010) Estimation of constant and time-varying dynamic parameters of HIV infection in a nonlinear differential equation model. Ann Appl Stat 4: 460-483.
    • (2010) Ann Appl Stat , vol.4 , pp. 460-483
    • Liang, H.1    Miao, H.2    Wu, H.3
  • 12
    • 21544447528 scopus 로고    scopus 로고
    • Modeling long-term HIV dynamics and antiretroviral response: effects of drug potency, pharmacokinetics, adherence, and drug resistance
    • Wu H, Huang Y, Acosta EP, Rosenkranz SL, Kuritzkes DR, et al. (2005) Modeling long-term HIV dynamics and antiretroviral response: effects of drug potency, pharmacokinetics, adherence, and drug resistance. J Acquir Immune Defic Syndr 39: 272-283.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 272-283
    • Wu, H.1    Huang, Y.2    Acosta, E.P.3    Rosenkranz, S.L.4    Kuritzkes, D.R.5
  • 13
    • 33745245700 scopus 로고    scopus 로고
    • Hierarchical bayesian methods for estimation of parameters in a longitudinal HIV dynamic system
    • Huang Y, Liu D, Wu H, (2006) Hierarchical bayesian methods for estimation of parameters in a longitudinal HIV dynamic system. Biometrics 62: 413-423.
    • (2006) Biometrics , vol.62 , pp. 413-423
    • Huang, Y.1    Liu, D.2    Wu, H.3
  • 14
    • 40449119394 scopus 로고    scopus 로고
    • Long-term HIV dynamic models incorporating drug adherence and resistance to treatment for prediction of virological responses
    • Huang Y, (2008) Long-term HIV dynamic models incorporating drug adherence and resistance to treatment for prediction of virological responses. Computational Statistics & Data Analysis 52: 3765-3778.
    • (2008) Computational Statistics & Data Analysis , vol.52 , pp. 3765-3778
    • Huang, Y.1
  • 15
    • 77956289669 scopus 로고    scopus 로고
    • Hierarchical bayesian inference for HIV dynamic differential equation models incorporating multiple treatment factors
    • Huang Y, Wu H, Acosta EP, (2010) Hierarchical bayesian inference for HIV dynamic differential equation models incorporating multiple treatment factors. Biom J 52: 470-486.
    • (2010) Biom J , vol.52 , pp. 470-486
    • Huang, Y.1    Wu, H.2    Acosta, E.P.3
  • 16
    • 0037102904 scopus 로고    scopus 로고
    • A Bayesian approach to parameter estimation in HIV dynamical models
    • Putter H, Heisterkamp SH, Lange JMA, de Wolf F, (2002) A Bayesian approach to parameter estimation in HIV dynamical models. Stat Med 21: 2199-2214.
    • (2002) Stat Med , vol.21 , pp. 2199-2214
    • Putter, H.1    Heisterkamp, S.H.2    Lange, J.M.A.3    de Wolf, F.4
  • 17
    • 0037385686 scopus 로고    scopus 로고
    • A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo
    • Markowitz M, Louie M, Hurley A, Sun E, Di Mascio M, et al. (2003) A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo. J Virol 77: 5037-5038.
    • (2003) J Virol , vol.77 , pp. 5037-5038
    • Markowitz, M.1    Louie, M.2    Hurley, A.3    Sun, E.4    Di Mascio, M.5
  • 18
    • 0027457101 scopus 로고
    • Dynamics of HIV infection of CD4+ T cells
    • Perelson A, (1993) Dynamics of HIV infection of CD4+ T cells. Mathematical Biosciences 114: 81-125.
    • (1993) Mathematical Biosciences , vol.114 , pp. 81-125
    • Perelson, A.1
  • 19
    • 0030952479 scopus 로고    scopus 로고
    • Decay characteristics of HIV-1-infected compartments during combination therapy
    • Perelson AS, Essunger P, Cao Y, Vesanen M, Hurley A, et al. (1997) Decay characteristics of HIV-1-infected compartments during combination therapy. Nature 387: 188-191.
    • (1997) Nature , vol.387 , pp. 188-191
    • Perelson, A.S.1    Essunger, P.2    Cao, Y.3    Vesanen, M.4    Hurley, A.5
  • 20
    • 0030869269 scopus 로고    scopus 로고
    • Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
    • Gulick RM, Mellors JW, Havlir D, Eron JJ, Gonzalez C, et al. (1997) Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 337: 734-739.
    • (1997) N Engl J Med , vol.337 , pp. 734-739
    • Gulick, R.M.1    Mellors, J.W.2    Havlir, D.3    Eron, J.J.4    Gonzalez, C.5
  • 21
    • 0033520673 scopus 로고    scopus 로고
    • Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy
    • Dornadula G, Zhang H, VanUitert B, Stern J, Livornese L, et al. (1999) Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy. JAMA 282: 1627-1632.
    • (1999) JAMA , vol.282 , pp. 1627-1632
    • Dornadula, G.1    Zhang, H.2    VanUitert, B.3    Stern, J.4    Livornese, L.5
  • 22
    • 10744228049 scopus 로고    scopus 로고
    • New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma
    • Palmer S, Wiegand AP, Maldarelli F, Bazmi H, Mican JM, et al. (2003) New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 41: 4531-4536.
    • (2003) J Clin Microbiol , vol.41 , pp. 4531-4536
    • Palmer, S.1    Wiegand, A.P.2    Maldarelli, F.3    Bazmi, H.4    Mican, J.M.5
  • 23
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
    • Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, et al. (1997) Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278: 1295-1300.
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1    Hermankova, M.2    Pierson, T.3    Carruth, L.M.4    Buck, C.5
  • 24
    • 0030659177 scopus 로고    scopus 로고
    • Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
    • Chun TW, Stuyver L, Mizell SB, Ehler LA, Mican JA, et al. (1997) Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci U S A 94: 13193-13197.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13193-13197
    • Chun, T.W.1    Stuyver, L.2    Mizell, S.B.3    Ehler, L.A.4    Mican, J.A.5
  • 25
    • 70449685916 scopus 로고    scopus 로고
    • A generalized multi-strain model of HIV evolution with implications for drug-resistance management
    • doi:10.1109/ACC.2009.5160358
    • Luo R, Piovoso M, Zurakowski R, (2009) A generalized multi-strain model of HIV evolution with implications for drug-resistance management. In: Proc. American Control Conference. pp. 2295-2300 doi:10.1109/ACC.2009.5160358.
    • (2009) Proc. American Control Conference , pp. 2295-2300
    • Luo, R.1    Piovoso, M.2    Zurakowski, R.3
  • 26
    • 73449117263 scopus 로고    scopus 로고
    • Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
    • Rong L, Perelson AS, (2009) Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy. PLoS Comput Biol 5: e1000533.
    • (2009) PLoS Comput Biol , vol.5
    • Rong, L.1    Perelson, A.S.2
  • 27
    • 68949196315 scopus 로고    scopus 로고
    • Modeling HIV persistence, the latent reservoir, and viral blips
    • Rong L, Perelson AS, (2009) Modeling HIV persistence, the latent reservoir, and viral blips. Journal of Theoretical Biology 260: 308-331.
    • (2009) Journal of Theoretical Biology , vol.260 , pp. 308-331
    • Rong, L.1    Perelson, A.S.2
  • 28
    • 34447648181 scopus 로고    scopus 로고
    • Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission
    • Smith DM, Wong JK, Shao H, Hightower GK, Mai SHT, et al. (2007) Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis 196: 356-360.
    • (2007) J Infect Dis , vol.196 , pp. 356-360
    • Smith, D.M.1    Wong, J.K.2    Shao, H.3    Hightower, G.K.4    Mai, S.H.T.5
  • 29
    • 0035341524 scopus 로고    scopus 로고
    • Residual human immunodeficiency virus (HIV) type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal uid after suppression of viremia for 2 years
    • Gunthard HF, Havlir DV, Fiscus S, Zhang ZQ, Eron J, et al. (2001) Residual human immunodeficiency virus (HIV) type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal uid after suppression of viremia for 2 years. J Infect Dis 183: 1318-1327.
    • (2001) J Infect Dis , vol.183 , pp. 1318-1327
    • Gunthard, H.F.1    Havlir, D.V.2    Fiscus, S.3    Zhang, Z.Q.4    Eron, J.5
  • 30
    • 41649083599 scopus 로고    scopus 로고
    • Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
    • Palmer S, Maldarelli F, Wiegand A, Bernstein B, Hanna GJ, et al. (2008) Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proc Natl Acad Sci U S A 105: 3879-3884.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3879-3884
    • Palmer, S.1    Maldarelli, F.2    Wiegand, A.3    Bernstein, B.4    Hanna, G.J.5
  • 31
    • 0036176509 scopus 로고    scopus 로고
    • The challenge of viral reservoirs in HIV-1 infection
    • Blankson JN, Persaud D, Siliciano RF, (2002) The challenge of viral reservoirs in HIV-1 infection. Annu Rev Med 53: 557-593.
    • (2002) Annu Rev Med , vol.53 , pp. 557-593
    • Blankson, J.N.1    Persaud, D.2    Siliciano, R.F.3
  • 32
    • 0032122490 scopus 로고    scopus 로고
    • Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy
    • Schrager LK, D'Souza MP, (1998) Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy. JAMA 280: 67-71.
    • (1998) JAMA , vol.280 , pp. 67-71
    • Schrager, L.K.1    D'Souza, M.P.2
  • 33
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun TW, Carruth L, Finzi D, Shen X, DiGiuseppe JA, et al. (1997) Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387: 183-188.
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.W.1    Carruth, L.2    Finzi, D.3    Shen, X.4    DiGiuseppe, J.A.5
  • 34
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency
    • Chun TW, Finzi D, Margolick J, Chadwick K, Schwartz D, et al. (1995) In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat Med 1: 1284-1290.
    • (1995) Nat Med , vol.1 , pp. 1284-1290
    • Chun, T.W.1    Finzi, D.2    Margolick, J.3    Chadwick, K.4    Schwartz, D.5
  • 35
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, et al. (2003) Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 9: 727-728.
    • (2003) Nat Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3    Quinn, T.C.4    Chadwick, K.5
  • 36
    • 0028375708 scopus 로고
    • On global identifiability for arbitrary model parameterizations
    • Ljung L, Glad S, (1994) On global identifiability for arbitrary model parameterizations. Automatica 30: 265-76.
    • (1994) Automatica , vol.30 , pp. 265-276
    • Ljung, L.1    Glad, S.2
  • 37
    • 0037399670 scopus 로고    scopus 로고
    • Parameter identifiability of nonlinear systems: the role of initial conditions
    • Saccomani MP, Audoly S, D'Angio L, (2003) Parameter identifiability of nonlinear systems: the role of initial conditions. Automatica 39: 619-632.
    • (2003) Automatica , vol.39 , pp. 619-632
    • Saccomani, M.P.1    Audoly, S.2    D'Angio, L.3
  • 38
    • 77950865238 scopus 로고    scopus 로고
    • Examples of testing global identifiability of biological and biomedical models with the daisy software
    • Saccomani MP, Audoly S, Bellu G, D'Angio L, (2010) Examples of testing global identifiability of biological and biomedical models with the daisy software. Computers in Biology and Medicine 40: 402-407.
    • (2010) Computers in Biology and Medicine , vol.40 , pp. 402-407
    • Saccomani, M.P.1    Audoly, S.2    Bellu, G.3    D'Angio, L.4
  • 39
    • 0004119251 scopus 로고
    • Providence, R.I.: American Mathematical Society
    • Ritt JF, (1950) Differential algebra. Providence, R.I.: American Mathematical Society.
    • (1950) Differential algebra
    • Ritt, J.F.1
  • 40
    • 0033589745 scopus 로고    scopus 로고
    • Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis
    • Ramratnam B, Bonhoeffer S, Binley J, Hurley A, Zhang L, et al. (1999) Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis. The Lancet 354: 1782-1785.
    • (1999) The Lancet , vol.354 , pp. 1782-1785
    • Ramratnam, B.1    Bonhoeffer, S.2    Binley, J.3    Hurley, A.4    Zhang, L.5
  • 41
    • 52449128028 scopus 로고    scopus 로고
    • A new strategy to decrease risk of resistance emerging during therapy switching in HIV treatment
    • doi:10.1109/ACC.2008.4586804
    • Luo R, Zurakowski R, (2008) A new strategy to decrease risk of resistance emerging during therapy switching in HIV treatment. In: Proc. American Control Conference. pp. 2112-2117 doi:10.1109/ACC.2008.4586804.
    • (2008) Proc. American Control Conference , pp. 2112-2117
    • Luo, R.1    Zurakowski, R.2
  • 43
    • 80455174313 scopus 로고    scopus 로고
    • Optimal Antiviral Switching to Minimize Resistance Risk in HIV Therapy
    • Luo R, Piovoso MJ, Martinez-Picado J, Zurakowski R, (2011) Optimal Antiviral Switching to Minimize Resistance Risk in HIV Therapy. PLoS ONE 6: e27047.
    • (2011) PLoS ONE , vol.6
    • Luo, R.1    Piovoso, M.J.2    Martinez-Picado, J.3    Zurakowski, R.4
  • 44
    • 37249076594 scopus 로고    scopus 로고
    • Antiretroviral therapy: optimal sequencing of therapy to avoid resistance
    • Martinez-Cajas JL, Wainberg MA, (2008) Antiretroviral therapy: optimal sequencing of therapy to avoid resistance. Drugs 68: 43-72.
    • (2008) Drugs , vol.68 , pp. 43-72
    • Martinez-Cajas, J.L.1    Wainberg, M.A.2
  • 45
    • 84864016280 scopus 로고    scopus 로고
    • Robust Closed-Loop Minimal Sampling Method for HIV Therapy Switching Strategies
    • doi:10.1109/TBME.2012.2201479, In Press
    • Cardozo EF, Zurakowski R, (2012) Robust Closed-Loop Minimal Sampling Method for HIV Therapy Switching Strategies. Biomedical Engineering, IEEE Transactions on 59: In press doi:10.1109/TBME.2012.2201479.
    • (2012) Biomedical Engineering, IEEE Transactions on , vol.59
    • Cardozo, E.F.1    Zurakowski, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.