Viremic relapse after HIV-1 remission in a perinatally infected child

New England Journal of Medicine

Volumn 372, Issue 8, 2014, Pages 786-788

  Luzuriaga, Katherine ^a   Gay, Hannah ^b   Ziemniak, Carrie ^c   Sanborn, Keri B ^a   Somasundaran, Mohan ^a   Rainwater Lovett, Kaitlin ^c   Mellors, John W ^d   Rosenbloom, Daniel ^e   Persaud, Deborah ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS DNA; VIRUS RNA;

ARTICLE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CHILD; DNA DETERMINATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; PERINATAL INFECTION; PHYLOGENY; REINFECTION; RELAPSE; REMISSION; VERTICAL TRANSMISSION; VIREMIA; VIRUS LATENCY; VIRUS LOAD; VIRUS REPLICATION; BLOOD; CASE REPORT; FOLLOW UP; GENETICS; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOLATION AND PURIFICATION; MOTHER; PHYSIOLOGY; PRESCHOOL CHILD; RECURRENT DISEASE; VIROLOGY;

ANTI-RETROVIRAL AGENTS; CHILD, PRESCHOOL; FOLLOW-UP STUDIES; HIV INFECTIONS; HIV-1; HUMANS; MOTHERS; PHYLOGENY; RECURRENCE; RNA, VIRAL; VIRAL LOAD; VIREMIA; VIRUS LATENCY;

EID: 84923064466     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1413931     Document Type: Letter

References (5)

1. Persaud D, Gay H, Ziemniak C, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 2013;369:1828-35.
2. Kishko M, Somasundaran M, Brewster F, et al. Genotypic and functional properties of early infant HIV-1 envelopes. Retrovirology 2011;8:67.
3. Tomaras GD, Haynes BF. HIV-1-specific antibody responses during acute and chronic HIV-1 infection. Curr Opin HIV AIDS 2009;4:373-9.
4. Wolinsky SM, Wike CM, Korber BT, et al. Selective transmission of human immunodeficiency virus type-1 variants from mothers to infants. Science 1992;255:1134-7.
5. Rainwater-Lovett K, Luzuriaga K, Persaud D. Very early combination antiretroviral therapy in infants: prospects for cure. Curr Opin HIV AIDS 2015;10:4-11.