Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses

Pharmacology Research and Perspectives

Volumn 3, Issue 2, 2015, Pages 1-15

  Keizer, Ron J ^a,b   Jansen, Robert S ^b   Rosing, Hilde ^b   Thijssen, Bas ^b   Beijnen, Jos H ^b,c   Schellens, Jan H M ^b,c   Huitema, Alwin D R ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Bioanalysis; BLOQ; Limit of quantification; Pharmacometrics; Population pharmacokinetics

Indexed keywords

ALGORITHM; ANALYTIC METHOD; ANALYTICAL ERROR; ANALYTICAL PARAMETERS; ARTICLE; CALIBRATION; COMPARTMENT MODEL; COMPUTER MODEL; COMPUTER SIMULATION; DATA PROCESSING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEARITY; MATHEMATICAL MODEL; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; PHARMACOKINETIC ASSAY; PRIORITY JOURNAL;

EID: 84964625903     PISSN: None     EISSN: 20521707     Source Type: Journal    
DOI: 10.1002/prp2.131     Document Type: Article

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